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Author: Mark R. Cookson

  • ORCiD: http://orcid.org/0000-0002-1058-3831
  • Most recently observed institution: Cell Biology and Gene Expression Section, Laboratory of Neurogenetics, National Institute on Aging

Rankings

  • All-time downloads: 14,178 (rank: 15,271 )
  • Categories:
    • animal behavior and cognition: 301 (rank: 4,782 (tie) )
    • biochemistry: 546 (rank: 11,444 (tie) )
    • bioinformatics: 490 (rank: 27,935 (tie) )
    • cell biology: 3,065 (rank: 1,786 (tie) )
    • genetic and genomic medicine: 370 (rank: 7,762 (tie) )
    • genetics: 2,685 (rank: 7,315 )
    • genomics: 755 (rank: 29,086 (tie) )
    • molecular biology: 522 (rank: 13,353 (tie) )
    • neurology: 422 (rank: 3,181 (tie) )
    • neuroscience: 5,022 (rank: 4,142 (tie) )

Downloads per author, site-wide

Preprints

LRRK2 mediates tubulation and vesicle sorting from membrane damaged lysosomes

cell biology more details view paper
  • Downloaded 2,049 times
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    • Site-wide: 8,412
    • In cell biology: 183
  • Year to date:
    • Site-wide: 49,681
  • Since beginning of last month:
    • Site-wide: 18,359

Large-scale pathway-specific polygenic risk, transcriptomic community networks and functional inferences in Parkinson disease

genetics more details view paper
  • Downloaded 1,462 times
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    • Site-wide: 13,895
    • In genetics: 635
  • Year to date:
    • Site-wide: 12,647
  • Since beginning of last month:
    • Site-wide: 83,335

APOE4 is Associated with Differential Regional Vulnerability to Bioenergetic Deficits in Aged APOE Mice

neuroscience more details view paper
  • Downloaded 1,281 times
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    • Site-wide: 16,985
    • In neuroscience: 2,027
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    • Site-wide: 19,013
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    • Site-wide: 34,133

Regulation of mitophagy by the NSL complex underlies genetic risk for Parkinson's disease at Chr16q11.2 and on the MAPT H1 allele

neuroscience more details view paper
  • Downloaded 1,078 times
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    • Site-wide: 21,866
    • In neuroscience: 2,725
  • Year to date:
    • Site-wide: 21,829
  • Since beginning of last month:
    • Site-wide: 19,232

Mutations in Auxilin cause parkinsonism via impaired clathrin-mediated trafficking at the Golgi apparatus and synapse

neuroscience more details view paper
  • Downloaded 938 times
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    • Site-wide: 26,807
    • In neuroscience: 3,469
  • Year to date:
    • Site-wide: 40,885
  • Since beginning of last month:
    • Site-wide: None

Common variation at the LRRK2 locus is associated with survival in the primary tauopathy progressive supranuclear palsy

genetics more details view paper
  • Downloaded 843 times
  • Download rankings, all-time:
    • Site-wide: 31,101
    • In genetics: 1,430
  • Year to date:
    • Site-wide: 61,551
  • Since beginning of last month:
    • Site-wide: 88,164

LAG3 is not expressed in human and murine neurons and does not modulate α-synucleinopathies

neuroscience more details view paper
  • Downloaded 833 times
  • Download rankings, all-time:
    • Site-wide: 31,686
    • In neuroscience: 4,195
  • Year to date:
    • Site-wide: 4,047
  • Since beginning of last month:
    • Site-wide: 1,594

The Foundational data initiative for Parkinsons disease (FOUNDIN-PD): enabling efficient translation from genetic maps to mechanism

genomics more details view paper
  • Downloaded 755 times
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    • Site-wide: 36,343
    • In genomics: 3,053
  • Year to date:
    • Site-wide: 4,674
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    • Site-wide: 13,361

Association of a common genetic variant with Parkinson's disease is propagated through microglia

neuroscience more details view paper
  • Downloaded 703 times
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    • Site-wide: 39,981
    • In neuroscience: 5,547
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    • Site-wide: 5,186
  • Since beginning of last month:
    • Site-wide: 44,393

Pathogenic mutations in LRRK2 sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia

cell biology more details view paper
  • Downloaded 596 times
  • Download rankings, all-time:
    • Site-wide: 49,504
    • In cell biology: 2,107
  • Year to date:
    • Site-wide: 27,754
  • Since beginning of last month:
    • Site-wide: 16,796

A revised 1.6 A structure of the GTPase domain of the Parkinson's disease-associated protein LRRK2 provides insights into mechanisms

biochemistry more details view paper
  • Downloaded 546 times
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    • Site-wide: 55,160
    • In biochemistry: 1,417
  • Year to date:
    • Site-wide: 78,998
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    • Site-wide: 73,463

Sequential screening nominates the Parkinson's disease associated kinase LRRK2 as a regulator of Clathrin-mediated endocytosis

molecular biology more details view paper
  • Downloaded 522 times
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    • Site-wide: 58,175
    • In molecular biology: 1,641
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    • Site-wide: 126,366
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    • Site-wide: 79,616

CoExp Web, a web tool for the exploitation of co-expression networks

bioinformatics more details view paper
  • Downloaded 490 times
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    • Site-wide: 62,593
    • In bioinformatics: 6,167
  • Year to date:
    • Site-wide: 24,237
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    • Site-wide: 30,547

Membrane targeting activates Leucine-rich repeat kinase 2 with differential effects on downstream Rab activation

cell biology more details view paper
  • Downloaded 420 times
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    • Site-wide: 73,488
    • In cell biology: 3,305
  • Year to date:
    • Site-wide: 38,149
  • Since beginning of last month:
    • Site-wide: 43,784

Genetic analysis of amyotrophic lateral sclerosis identifies contributing pathways and cell types.

genetics more details view paper
  • Downloaded 380 times
  • Download rankings, all-time:
    • Site-wide: 80,762
    • In genetics: 3,524
  • Year to date:
    • Site-wide: 84,624
  • Since beginning of last month:
    • Site-wide: None

Quality Control Metrics for Whole Blood Transcriptome Analysis in the Parkinson's Progression Markers Initiative (PPMI)

genetic and genomic medicine more details view paper
  • Downloaded 370 times
  • Download rankings, all-time:
    • Site-wide: 82,565
    • In genetic and genomic medicine: 353
  • Year to date:
    • Site-wide: 13,179
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    • Site-wide: 32,905

Combined knockout of Lrrk2 and Rab29 does not result in behavioral abnormalities in vivo

animal behavior and cognition more details view paper
  • Downloaded 301 times
  • Download rankings, all-time:
    • Site-wide: 97,541
    • In animal behavior and cognition: 1,126
  • Year to date:
    • Site-wide: 82,090
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    • Site-wide: 88,767

Evidence for GRN as part of a neuroinflammatory mechanism connecting common neurodegenerative diseases.

neurology more details view paper
  • Downloaded 283 times
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    • Site-wide: 101,492
    • In neurology: 321
  • Year to date:
    • Site-wide: 76,453
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THAP1 Modulates Oligodendrocyte Maturation by Regulating ECM Degradation in Lysosomes

neuroscience more details view paper
  • Downloaded 189 times
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    • Site-wide: 124,629
    • In neuroscience: 19,065
  • Year to date:
    • Site-wide: 100,584
  • Since beginning of last month:
    • Site-wide: None

LRRK2 coding variants and the risk of Parkinson's disease

neurology more details view paper
  • Downloaded 139 times
  • Download rankings, all-time:
    • Site-wide: 136,062
    • In neurology: 648
  • Year to date:
    • Site-wide: 46,122
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    • Site-wide: 21,711

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