Author: Ruotian Jiang

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Preprints

Structure of Mpro from COVID-19 virus and discovery of its inhibitors

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  • Site-wide: 272
  • In biochemistry: 1
• Year to date:
  • Site-wide: 1,049
• Since beginning of last month:
  • Site-wide: 1,049

Structural Basis for the Inhibition of the RNA-Dependent RNA Polymerase from SARS-CoV-2 by Remdesivir

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  • Site-wide: 1,123
  • In molecular biology: 17
• Year to date:
  • Site-wide: 11,554
• Since beginning of last month:
  • Site-wide: 11,554

Discovery of baicalin and baicalein as novel, natural product inhibitors of SARS-CoV-2 3CL protease in vitro

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  • Site-wide: 2,864
  • In molecular biology: 63
• Year to date:
  • Site-wide: 4,451
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  • Site-wide: 4,451

The Dynamic Conformational Landscapes of the Protein Methyltransferase SETD8

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  • Site-wide: 8,356
  • In biophysics: 181
• Year to date:
  • Site-wide: 90,797
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  • Site-wide: 90,797

Structure Basis for Inhibition of SARS-CoV-2 by the Feline Drug GC376

• Downloaded 993 times
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  • Site-wide: 19,688
  • In biophysics: 534
• Year to date:
  • Site-wide: 18,118
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  • Site-wide: 18,118

SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damage and constitutes an antiviral target

• Downloaded 754 times
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  • Site-wide: 29,045
  • In microbiology: 1,709
• Year to date:
  • Site-wide: 23,951
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  • Site-wide: 23,951

Selective Activation of TASK-3-containing K+ Channels Reveals Their Therapeutic Potentials in Analgesia

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  • Site-wide: 52,829
  • In pharmacology and toxicology: 309
• Year to date:
  • Site-wide: 57,058
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  • Site-wide: 57,058

Astroglial dysfunctions drive aberrant synaptogenesis in developing brain with lengthy general anesthesia

• Downloaded 313 times
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  • Site-wide: 77,410
  • In neuroscience: 11,948
• Year to date:
  • Site-wide: 90,481
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  • Site-wide: 90,481

Automated design and optimization of multitarget schizophrenia drug candidates by deep learning

• Downloaded 255 times
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  • Site-wide: 89,334
  • In bioinformatics: 7,889
• Year to date:
  • Site-wide: 75,245
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  • Site-wide: 75,245

Computational target fishing by mining transcriptional data using a novel Siamese spectral-based graph convolutional network

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• Download rankings, all-time:
  • Site-wide: 95,296
  • In bioinformatics: 8,287
• Year to date:
  • Site-wide: 50,684
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  • Site-wide: 50,684