Author: Wei Wang

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Preprints

The inner membrane protein YhdP modulates the rate of anterograde phospholipid flow in Escherichia coli

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Modified TCA/acetone precipitation of plant proteins for proteomic analysis

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Is Oculudentavis a bird or even archosaur?

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Systematic mapping of chromatin state landscapes during mouse development

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CRISPR-Cas13d induces efficient mRNA knock-down in animal embryos

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A single cell transcriptional roadmap for cardiopharyngeal fate diversification

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Assessment of single cell RNA-seq normalization methods

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Spatially clustered loci with multiple enhancers are frequent targets of HIV-1

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Establishment In Culture Of Expanded Potential Stem Cells

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The Effectiveness of China’s National Forest Protection Program and National-level Nature Reserves, 2000 to 2010

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GSKB: A gene set database for pathway analysis in mouse

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Identification of DNA motifs that regulate DNA methylation

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Single-cell transcriptome profiling of the Ciona larval brain

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Assessing the measurement transfer function of single-cell RNA sequencing

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Hybrid origins and the earliest stages of diploidization in the highly successful recent polyploid Capsella bursa-pastoris

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Finding de novo methylated DNA motifs

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TahcoRoll: An Efficient Approach for Signature Profiling in Genomic Data through Variable-Length k-mers

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The RNA-binding ATPase, Armitage, Couples piRNA Amplification in Nuage to Phased piRNA Production on Mitochondria

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Loss of SATB1 Induces a p21 Dependent Cellular Senescence Phenotype in Dopaminergic Neurons

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Full-genome evolutionary histories of selfing, splitting and selection in Caenorhabditis

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Co-expression enrichment analysis at the single-cell level reveals convergent defects in neural progenitor cells and their cell-type transitions in neurodevelopmental disorders

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Molecular Crowding Tunes Material States of Ribonucleoprotein Condensates

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In-Vivo Toxicity Studies and In-Vitro Inactivation of SARS-CoV-2 by Povidone-iodine In-situ Gel Forming Formulations

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A nuclear hormone receptor and lipid metabolism axis are required for the maintenance and regeneration of reproductive organs

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Systems-level identification of transcription factors critical for mouse embryonic development

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Identification of gut microbiome markers for schizophrenia delineates a potential role of Streptococcus

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Molecular evolution across developmental time reveals rapid divergence in early embryogenesis

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An FGF-driven feed-forward circuit patterns the cardiopharyngeal mesoderm in space and time

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Contemporary circulating enterovirus D68 strains show differential viral entry and replication in human neuronal cells

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Systematic identification of cooperation between DNA binding proteins in 3D space

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MiniScrub: de novo long read scrubbing using approximate alignment and deep learning

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Paralogues of the PXY and ER receptor kinases enforce radial patterning in plant vascular tissue.

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Computational Study of Ions and Water Permeation and Transportation Mechanisms of the SARS-CoV-2 Pentameric E Protein Channel

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Lasagna: Multifaceted Protein-Protein Interaction Prediction Based on Siamese Residual RCNN

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Role of short-chain fatty acids in the gut-brain axis in schizophrenia: contribution to immune activation and pathophysiology in humans and mice

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Interplay Between Short-range Attraction and Long-range Repulsion Controls Reentrant Liquid Condensation of Ribonucleoprotein-RNA Complexes

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SHP2 Inhibition Abrogates Adaptive Resistance to KRASG12C-Inhibition and Remodels the Tumor Microenvironment of KRAS-Mutant Tumors

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Xist Intron 1 Repression by TALE Transcriptional Factor Improves Somatic Cell Reprogamming in Mice

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Motto: Representing motifs in consensus sequences with minimum information loss

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Prophase removal of chromosome-associated RNAs facilitates anaphase chromosome segregation

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Global variability of the human IgG glycome

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Genome structure predicts modular transcriptome responses to genetic and environmental conditions

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Mechanisms of integrin αVβ5 clustering in flat clathrin lattices

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Nationwide population genetic screening improves outcomes of newborn screening for hearing loss in China

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Genome-wide study identifies association between HLA-B*55:01 and penicillin allergy

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Non-parametric and semi-parametric support estimation using SEquential RESampling random walks on biomolecular sequences

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Neurogenin regulates effectors of migratory neuron cell behaviors in Ciona

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A single-cell transcriptome atlas of the aging human and macaque retina

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Spontaneous dormancy protects Trypanosoma cruzi during extended drug exposure

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Identification of 67 pleiotropic genes for seven autoimmune diseases using multivariate statistical analysis

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Cell Cycle, Energy Metabolism and DNA Repair Pathways in Cancer Cells are Suppressed by Compound Kushen Injection.

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Targeted mutations on 3D hub loci alter spatial interaction environment

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Structure-function analysis of Arabidopsis TOPLESS reveals conservation of repression mechanisms across eukaryotes

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Screening of FDA-approved Drugs and Identification of Novel Lassa Virus Entry Inhibitors

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JEDI: Circular RNA Prediction based on Junction Encoders and Deep Interaction among Splice Sites

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Fecal microbiota as a non-invasive biomarker to predict the tissue iron accumulation in intestine epithelial cells and liver

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Mutation effect estimation on protein-protein interactions using deep contextualized representation learning

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Loss of Dnmt3a dependent methylation in inhibitory neurons impairs neural function through a mechanism that impacts Rett syndrome

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Bacterial Glycogen as a Durable Energy Reserve Contributing to Persistence: An Updated Bibliography and Mathematical Model

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Uncovering Medical Insights from Vast Amounts of Biomedical Data in Clinical Case Reports

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The Effect of Compound Kushen Injection on Cancer Cells: Integrated Identification of Candidate Molecular Mechanisms.

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Human Cytomegalovirus Immediate-Early 1 Protein Causes Loss of SOX2 from Neural Progenitor Cells by Trapping Unphosphorylated STAT3 in the Nucleus

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Dual functions of Discoidin domain receptor coordinate cell-matrix adhesion and collective polarity in migratory cardiopharyngeal progenitors

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Cell cycle-gated feedback control mediates desensitization to interferon stimulation

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Contextual Regression: An Accurate and Conveniently Interpretable Nonlinear Model for Mining Discovery from Scientific Data

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Genome-wide analysis identifies cis-acting elements regulating mRNA polyadenylation and translation during vertebrate oocyte maturation

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Structural basis for transfer RNA mimicry by a bacterial Y RNA

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DTI-CDF: a CDF model towards the prediction of DTIs based on hybrid features

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Chemical, physical and biological triggers of Bcl-xL-mediated apoptosis

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A new strategy for identifying mechanisms of drug-drug interaction using transcriptome analysis: Compound Kushen injection as a proof of principle

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Genome-wide association analysis and replication in 810,625 individuals identifies novel therapeutic targets for varicose veins

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Understanding the Mechanistic Contribution of Herbal Extracts in Compound Kushen Injection with Transcriptome Analysis

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Sulforaphane modulates microRNA expression in colon cancer cells to implicate the regulation of oncogenes CDC25A, HMGA2 and MYC

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Build a Better Bootstrap and the RAWR Shall Beat a Random Path to Your Door: Phylogenetic Support Estimation Revisited

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Exploring the Changing Landscape of Cell-to-Cell Variation After CTCF Knockdown via Single Cell RNA-seq

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Role of Water Mediated Interactions in Calcium-Coupled Allostery of Calmodulin Domains

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Comparative Transcriptomes Analysis of Taenia pisiformis at Different Development Stages

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Autophagy Decreases Alveolar Epithelial Cell Injury by Suppressing the NF-κB Signaling Pathway and Regulating the Release of Inflammatory Mediators

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Androgen Promotes Differentiation of PLZF+ Spermatogonia pool via Indirect Regulatory Pattern

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Thm2 interacts with paralog, Thm1, and sensitizes to Hedgehog signaling in postnatal skeletogenesis

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Latent defense response to non-pathogenic microbial factors impairs plant-rhizobacteria mutualism

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Heterodimerization of UNC-13/RIM regulates synaptic vesicle release probability but not priming

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Integrative analysis with expanded DNA methylation data reveals common key regulators and pathways in cancers

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Testosterone Changes in Female Pandas in Estrus

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Genetic interaction of mammalian IFT-A paralogs regulates cilia disassembly, ciliary protein trafficking, Hedgehog signaling and embryogenesis

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Loss of tissue non-specific alkaline phosphatase (TNAP) enzyme activity in cerebral microvessels is coupled to persistent neuroinflammation and behavioral deficits in late sepsis

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Association between ocular biometrical parameters and diabetic retinopathy in Chinese adults with type 2 diabetes mellitus

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Bio-JOIE: Joint Representation Learning of Biological Knowledge Bases

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Transduction catalysis: doxorubicin accelerates and enhances rAAV-mediated gene expression in the cortex of mouse, cat and monkey

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Increased p53 signaling impairs neural differentiation causing HUWE1-promoted intellectual disabilities

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Intraflagellar transport-A deficiency ameliorates ADPKD renal cystogenesis in a renal tubular- and maturation-dependent manner

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Experimental Stroke Induces Chronic Gut Dysbiosis and Neuroinflammation in Male Mice

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Recovery of Consciousness and Cognition after General Anesthesia in Humans

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Mechanical dysfunction induced by a hypertrophic cardiomyopathy mutation is the primary driver of cellular adaptation

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The influence of insulin therapy on measurements of optical coherence tomography parameters in diabetic patients without retinopathy

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Prediction of LncRNA Encoded Small Peptides in Glioma and The Oligomer Channel Functional Analysis Using in Silico Approaches

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Genome-wide identification of long non-coding RNAs in the gravid ectoparasite Varroa destructor

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Strain-specific genome evolution in Trypanosoma cruzi, the agent of Chagas disease

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Limbal Niche Cells in Three-Dimensional Matrigel Induced Dedifferentiation of Mature Corneal Epithelial Cells toward a Progenitor State

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Screening of Botanical Drugs Against Lassa Virus Entry

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