Author: Wei Wang

Downloads per author, site-wide

Preprints

Brassinosteroids Promote Parenchyma Cell and Secondary Xylem Development in Sugar Beet (Beta vulgaris L.) Root

No bioRxiv download data for this paper yet.

Modified TCA/acetone precipitation of plant proteins for proteomic analysis

• Downloaded 4,583 times
• Download rankings, all-time:
  • Site-wide: 945 out of 100,173
  • In biochemistry: 25 out of 3,421
• Year to date:
  • Site-wide: 1,625 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Is Oculudentavis a bird or even archosaur?

• Downloaded 4,569 times
• Download rankings, all-time:
  • Site-wide: 955 out of 100,173
  • In evolutionary biology: 24 out of 5,984
• Year to date:
  • Site-wide: 277 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Systematic mapping of chromatin state landscapes during mouse development

• Downloaded 4,385 times
• Download rankings, all-time:
  • Site-wide: 1,034 out of 100,173
  • In genomics: 211 out of 6,213
• Year to date:
  • Site-wide: 3,222 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

CRISPR-Cas13d induces efficient mRNA knock-down in animal embryos

• Downloaded 3,092 times
• Download rankings, all-time:
  • Site-wide: 1,908 out of 100,173
  • In developmental biology: 24 out of 2,997
• Year to date:
  • Site-wide: 438 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

A single cell transcriptional roadmap for cardiopharyngeal fate diversification

• Downloaded 2,515 times
• Download rankings, all-time:
  • Site-wide: 2,693 out of 100,173
  • In developmental biology: 42 out of 2,997
• Year to date:
  • Site-wide: 14,123 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Assessment of single cell RNA-seq normalization methods

• Downloaded 2,181 times
• Download rankings, all-time:
  • Site-wide: 3,412 out of 100,173
  • In bioinformatics: 616 out of 9,208
• Year to date:
  • Site-wide: 72,731 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Spatially clustered loci with multiple enhancers are frequent targets of HIV-1

• Downloaded 1,625 times
• Download rankings, all-time:
  • Site-wide: 5,523 out of 100,173
  • In genomics: 892 out of 6,213
• Year to date:
  • Site-wide: 37,226 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Establishment In Culture Of Expanded Potential Stem Cells

• Downloaded 1,610 times
• Download rankings, all-time:
  • Site-wide: 5,617 out of 100,173
  • In developmental biology: 101 out of 2,997
• Year to date:
  • Site-wide: 37,482 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

The Effectiveness of China’s National Forest Protection Program and National-level Nature Reserves, 2000 to 2010

• Downloaded 1,427 times
• Download rankings, all-time:
  • Site-wide: 6,864 out of 100,173
  • In ecology: 124 out of 4,398
• Year to date:
  • Site-wide: 42,395 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

GSKB: A gene set database for pathway analysis in mouse

• Downloaded 1,278 times
• Download rankings, all-time:
  • Site-wide: 8,287 out of 100,173
  • In bioinformatics: 1,398 out of 9,208
• Year to date:
  • Site-wide: 15,360 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Identification of DNA motifs that regulate DNA methylation

• Downloaded 1,169 times
• Download rankings, all-time:
  • Site-wide: 9,637 out of 100,173
  • In bioinformatics: 1,577 out of 9,208
• Year to date:
  • Site-wide: 29,030 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Single-cell transcriptome profiling of the Ciona larval brain

• Downloaded 1,150 times
• Download rankings, all-time:
  • Site-wide: 9,898 out of 100,173
  • In developmental biology: 196 out of 2,997
• Year to date:
  • Site-wide: 32,723 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Assessing the measurement transfer function of single-cell RNA sequencing

• Downloaded 1,067 times
• Download rankings, all-time:
  • Site-wide: 11,196 out of 100,173
  • In genomics: 1,569 out of 6,213
• Year to date:
  • Site-wide: 87,178 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Hybrid origins and the earliest stages of diploidization in the highly successful recent polyploid Capsella bursa-pastoris

• Downloaded 1,021 times
• Download rankings, all-time:
  • Site-wide: 12,024 out of 100,173
  • In evolutionary biology: 669 out of 5,984
• Year to date:
  • Site-wide: 82,955 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Finding de novo methylated DNA motifs

• Downloaded 963 times
• Download rankings, all-time:
  • Site-wide: 13,163 out of 100,173
  • In bioinformatics: 2,061 out of 9,208
• Year to date:
  • Site-wide: 53,425 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

TahcoRoll: An Efficient Approach for Signature Profiling in Genomic Data through Variable-Length k-mers

• Downloaded 928 times
• Download rankings, all-time:
  • Site-wide: 13,962 out of 100,173
  • In bioinformatics: 2,166 out of 9,208
• Year to date:
  • Site-wide: 25,485 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

The RNA-binding ATPase, Armitage, Couples piRNA Amplification in Nuage to Phased piRNA Production on Mitochondria

• Downloaded 909 times
• Download rankings, all-time:
  • Site-wide: 14,414 out of 100,173
  • In genetics: 936 out of 4,991
• Year to date:
  • Site-wide: 36,656 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Loss of SATB1 Induces a p21 Dependent Cellular Senescence Phenotype in Dopaminergic Neurons

• Downloaded 817 times
• Download rankings, all-time:
  • Site-wide: 17,028 out of 100,173
  • In neuroscience: 2,748 out of 17,827
• Year to date:
  • Site-wide: 34,808 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Full-genome evolutionary histories of selfing, splitting and selection in Caenorhabditis

• Downloaded 791 times
• Download rankings, all-time:
  • Site-wide: 17,907 out of 100,173
  • In genomics: 2,199 out of 6,213
• Year to date:
  • Site-wide: 87,230 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

In-Vivo Toxicity Studies and In-Vitro Inactivation of SARS-CoV-2 by Povidone-iodine In-situ Gel Forming Formulations

• Downloaded 778 times
• Download rankings, all-time:
  • Site-wide: 18,386 out of 100,173
  • In microbiology: 1,195 out of 8,867
• Year to date:
  • Site-wide: 2,962 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Co-expression enrichment analysis at the single-cell level reveals convergent defects in neural progenitor cells and their cell-type transitions in neurodevelopmental disorders

• Downloaded 776 times
• Download rankings, all-time:
  • Site-wide: 18,451 out of 100,173
  • In genetics: 1,158 out of 4,991
• Year to date:
  • Site-wide: 2,980 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Molecular Crowding Tunes Material States of Ribonucleoprotein Condensates

• Downloaded 768 times
• Download rankings, all-time:
  • Site-wide: 18,740 out of 100,173
  • In biophysics: 639 out of 4,409
• Year to date:
  • Site-wide: 21,918 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Identification of gut microbiome markers for schizophrenia delineates a potential role of Streptococcus

• Downloaded 701 times
• Download rankings, all-time:
  • Site-wide: 21,433 out of 100,173
  • In microbiology: 1,409 out of 8,867
• Year to date:
  • Site-wide: 15,098 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

A nuclear hormone receptor and lipid metabolism axis are required for the maintenance and regeneration of reproductive organs

• Downloaded 695 times
• Download rankings, all-time:
  • Site-wide: 21,722 out of 100,173
  • In developmental biology: 543 out of 2,997
• Year to date:
  • Site-wide: 47,936 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Systems-level identification of transcription factors critical for mouse embryonic development

• Downloaded 686 times
• Download rankings, all-time:
  • Site-wide: 22,207 out of 100,173
  • In bioinformatics: 3,152 out of 9,208
• Year to date:
  • Site-wide: 84,459 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Molecular evolution across developmental time reveals rapid divergence in early embryogenesis

• Downloaded 677 times
• Download rankings, all-time:
  • Site-wide: 22,587 out of 100,173
  • In evolutionary biology: 1,435 out of 5,984
• Year to date:
  • Site-wide: 37,088 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

An FGF-driven feed-forward circuit patterns the cardiopharyngeal mesoderm in space and time

• Downloaded 665 times
• Download rankings, all-time:
  • Site-wide: 23,205 out of 100,173
  • In developmental biology: 584 out of 2,997
• Year to date:
  • Site-wide: 69,077 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Contemporary circulating enterovirus D68 strains show differential viral entry and replication in human neuronal cells

• Downloaded 642 times
• Download rankings, all-time:
  • Site-wide: 24,441 out of 100,173
  • In microbiology: 1,610 out of 8,867
• Year to date:
  • Site-wide: 48,999 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Systematic identification of cooperation between DNA binding proteins in 3D space

• Downloaded 640 times
• Download rankings, all-time:
  • Site-wide: 24,515 out of 100,173
  • In bioinformatics: 3,407 out of 9,208
• Year to date:
  • Site-wide: 86,633 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

MiniScrub: de novo long read scrubbing using approximate alignment and deep learning

• Downloaded 613 times
• Download rankings, all-time:
  • Site-wide: 26,005 out of 100,173
  • In bioinformatics: 3,563 out of 9,208
• Year to date:
  • Site-wide: 49,531 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Computational Study of Ions and Water Permeation and Transportation Mechanisms of the SARS-CoV-2 Pentameric E Protein Channel

• Downloaded 599 times
• Download rankings, all-time:
  • Site-wide: 26,864 out of 100,173
  • In biophysics: 1,014 out of 4,409
• Year to date:
  • Site-wide: 4,410 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Paralogues of the PXY and ER receptor kinases enforce radial patterning in plant vascular tissue.

• Downloaded 599 times
• Download rankings, all-time:
  • Site-wide: 26,899 out of 100,173
  • In plant biology: 664 out of 3,162
• Year to date:
  • Site-wide: 45,363 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Lasagna: Multifaceted Protein-Protein Interaction Prediction Based on Siamese Residual RCNN

• Downloaded 564 times
• Download rankings, all-time:
  • Site-wide: 29,016 out of 100,173
  • In bioinformatics: 3,863 out of 9,208
• Year to date:
  • Site-wide: 57,967 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

SHP2 Inhibition Abrogates Adaptive Resistance to KRASG12C-Inhibition and Remodels the Tumor Microenvironment of KRAS-Mutant Tumors

• Downloaded 557 times
• Download rankings, all-time:
  • Site-wide: 29,508 out of 100,173
  • In cancer biology: 926 out of 3,582
• Year to date:
  • Site-wide: 4,945 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Role of short-chain fatty acids in the gut-brain axis in schizophrenia: contribution to immune activation and pathophysiology in humans and mice

• Downloaded 548 times
• Download rankings, all-time:
  • Site-wide: 30,104 out of 100,173
  • In neuroscience: 5,107 out of 17,827
• Year to date:
  • Site-wide: 5,071 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Xist Intron 1 Repression by TALE Transcriptional Factor Improves Somatic Cell Reprogamming in Mice

• Downloaded 491 times
• Download rankings, all-time:
  • Site-wide: 34,614 out of 100,173
  • In developmental biology: 970 out of 2,997
• Year to date:
  • Site-wide: 86,024 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Interplay Between Short-range Attraction and Long-range Repulsion Controls Reentrant Liquid Condensation of Ribonucleoprotein-RNA Complexes

• Downloaded 490 times
• Download rankings, all-time:
  • Site-wide: 34,704 out of 100,173
  • In biophysics: 1,365 out of 4,409
• Year to date:
  • Site-wide: 56,932 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Global variability of the human IgG glycome

• Downloaded 473 times
• Download rankings, all-time:
  • Site-wide: 36,208 out of 100,173
  • In biochemistry: 1,054 out of 3,421
• Year to date:
  • Site-wide: 42,459 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Motto: Representing motifs in consensus sequences with minimum information loss

• Downloaded 470 times
• Download rankings, all-time:
  • Site-wide: 36,523 out of 100,173
  • In bioinformatics: 4,560 out of 9,208
• Year to date:
  • Site-wide: 28,411 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Prophase removal of chromosome-associated RNAs facilitates anaphase chromosome segregation

• Downloaded 460 times
• Download rankings, all-time:
  • Site-wide: 37,486 out of 100,173
  • In cell biology: 1,822 out of 5,188
• Year to date:
  • Site-wide: 26,828 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Mechanisms of integrin αVβ5 clustering in flat clathrin lattices

• Downloaded 451 times
• Download rankings, all-time:
  • Site-wide: 38,267 out of 100,173
  • In cell biology: 1,865 out of 5,188
• Year to date:
  • Site-wide: 38,677 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Genome structure predicts modular transcriptome responses to genetic and environmental conditions

• Downloaded 450 times
• Download rankings, all-time:
  • Site-wide: 38,403 out of 100,173
  • In genomics: 3,608 out of 6,213
• Year to date:
  • Site-wide: 65,840 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Nationwide population genetic screening improves outcomes of newborn screening for hearing loss in China

• Downloaded 446 times
• Download rankings, all-time:
  • Site-wide: 38,805 out of 100,173
  • In genetics: 2,243 out of 4,991
• Year to date:
  • Site-wide: 36,734 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Genome-wide study identifies association between HLA-B*55:01 and penicillin allergy

• Downloaded 444 times
• Download rankings, all-time:
  • Site-wide: 39,002 out of 100,173
  • In genetics: 2,261 out of 4,991
• Year to date:
  • Site-wide: 6,987 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Neurogenin regulates effectors of migratory neuron cell behaviors in Ciona

• Downloaded 434 times
• Download rankings, all-time:
  • Site-wide: 40,088 out of 100,173
  • In developmental biology: 1,162 out of 2,997
• Year to date:
  • Site-wide: 47,049 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Non-parametric and semi-parametric support estimation using SEquential RESampling random walks on biomolecular sequences

• Downloaded 433 times
• Download rankings, all-time:
  • Site-wide: 40,207 out of 100,173
  • In bioinformatics: 4,886 out of 9,208
• Year to date:
  • Site-wide: 44,597 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Spontaneous dormancy protects Trypanosoma cruzi during extended drug exposure

• Downloaded 427 times
• Download rankings, all-time:
  • Site-wide: 40,785 out of 100,173
  • In microbiology: 2,888 out of 8,867
• Year to date:
  • Site-wide: 67,289 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Identification of 67 pleiotropic genes for seven autoimmune diseases using multivariate statistical analysis

• Downloaded 422 times
• Download rankings, all-time:
  • Site-wide: 41,337 out of 100,173
  • In genetics: 2,385 out of 4,991
• Year to date:
  • Site-wide: 42,495 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Cell Cycle, Energy Metabolism and DNA Repair Pathways in Cancer Cells are Suppressed by Compound Kushen Injection.

• Downloaded 409 times
• Download rankings, all-time:
  • Site-wide: 42,717 out of 100,173
  • In cancer biology: 1,355 out of 3,582
• Year to date:
  • Site-wide: 63,844 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Targeted mutations on 3D hub loci alter spatial interaction environment

• Downloaded 393 times
• Download rankings, all-time:
  • Site-wide: 44,638 out of 100,173
  • In biophysics: 1,809 out of 4,409
• Year to date:
  • Site-wide: 93,579 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Screening of FDA-approved Drugs and Identification of Novel Lassa Virus Entry Inhibitors

• Downloaded 392 times
• Download rankings, all-time:
  • Site-wide: 44,742 out of 100,173
  • In microbiology: 3,217 out of 8,867
• Year to date:
  • Site-wide: 54,103 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

JEDI: Circular RNA Prediction based on Junction Encoders and Deep Interaction among Splice Sites

• Downloaded 369 times
• Download rankings, all-time:
  • Site-wide: 47,515 out of 100,173
  • In bioinformatics: 5,508 out of 9,208
• Year to date:
  • Site-wide: 9,342 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Fecal microbiota as a non-invasive biomarker to predict the tissue iron accumulation in intestine epithelial cells and liver

• Downloaded 357 times
• Download rankings, all-time:
  • Site-wide: 49,103 out of 100,173
  • In microbiology: 3,604 out of 8,867
• Year to date:
  • Site-wide: 52,355 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Mutation effect estimation on protein-protein interactions using deep contextualized representation learning

• Downloaded 353 times
• Download rankings, all-time:
  • Site-wide: 49,584 out of 100,173
  • In bioinformatics: 5,692 out of 9,208
• Year to date:
  • Site-wide: 18,251 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Loss of Dnmt3a dependent methylation in inhibitory neurons impairs neural function through a mechanism that impacts Rett syndrome

• Downloaded 339 times
• Download rankings, all-time:
  • Site-wide: 51,522 out of 100,173
  • In neuroscience: 9,044 out of 17,827
• Year to date:
  • Site-wide: 37,237 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Bacterial Glycogen as a Durable Energy Reserve Contributing to Persistence: An Updated Bibliography and Mathematical Model

• Downloaded 337 times
• Download rankings, all-time:
  • Site-wide: 51,803 out of 100,173
  • In microbiology: 3,846 out of 8,867
• Year to date:
  • Site-wide: 40,609 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Uncovering Medical Insights from Vast Amounts of Biomedical Data in Clinical Case Reports

• Downloaded 335 times
• Download rankings, all-time:
  • Site-wide: 52,161 out of 100,173
  • In bioinformatics: 5,900 out of 9,208
• Year to date:
  • Site-wide: 77,550 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

The Effect of Compound Kushen Injection on Cancer Cells: Integrated Identification of Candidate Molecular Mechanisms.

• Downloaded 334 times
• Download rankings, all-time:
  • Site-wide: 52,216 out of 100,173
  • In pharmacology and toxicology: 357 out of 971
• Year to date:
  • Site-wide: 66,594 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Human Cytomegalovirus Immediate-Early 1 Protein Causes Loss of SOX2 from Neural Progenitor Cells by Trapping Unphosphorylated STAT3 in the Nucleus

• Downloaded 319 times
• Download rankings, all-time:
  • Site-wide: 54,451 out of 100,173
  • In microbiology: 4,089 out of 8,867
• Year to date:
  • Site-wide: 54,547 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Dual functions of Discoidin domain receptor coordinate cell-matrix adhesion and collective polarity in migratory cardiopharyngeal progenitors

• Downloaded 318 times
• Download rankings, all-time:
  • Site-wide: 54,599 out of 100,173
  • In developmental biology: 1,650 out of 2,997
• Year to date:
  • Site-wide: 88,510 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Cell cycle-gated feedback control mediates desensitization to interferon stimulation

• Downloaded 315 times
• Download rankings, all-time:
  • Site-wide: 55,102 out of 100,173
  • In systems biology: 1,595 out of 2,549
• Year to date:
  • Site-wide: 11,897 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Genome-wide analysis identifies cis-acting elements regulating mRNA polyadenylation and translation during vertebrate oocyte maturation

• Downloaded 298 times
• Download rankings, all-time:
  • Site-wide: 57,620 out of 100,173
  • In genomics: 4,629 out of 6,213
• Year to date:
  • Site-wide: 46,239 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Contextual Regression: An Accurate and Conveniently Interpretable Nonlinear Model for Mining Discovery from Scientific Data

• Downloaded 297 times
• Download rankings, all-time:
  • Site-wide: 57,734 out of 100,173
  • In bioinformatics: 6,334 out of 9,208
• Year to date:
  • Site-wide: 89,484 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Structural basis for transfer RNA mimicry by a bacterial Y RNA

• Downloaded 289 times
• Download rankings, all-time:
  • Site-wide: 59,021 out of 100,173
  • In biochemistry: 1,818 out of 3,421
• Year to date:
  • Site-wide: 89,197 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

DTI-CDF: a CDF model towards the prediction of DTIs based on hybrid features

• Downloaded 289 times
• Download rankings, all-time:
  • Site-wide: 59,092 out of 100,173
  • In bioinformatics: 6,429 out of 9,208
• Year to date:
  • Site-wide: 57,610 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Chemical, physical and biological triggers of Bcl-xL-mediated apoptosis

• Downloaded 276 times
• Download rankings, all-time:
  • Site-wide: 61,142 out of 100,173
  • In cancer biology: 1,973 out of 3,582
• Year to date:
  • Site-wide: 14,453 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Genome-wide association analysis and replication in 810,625 individuals identifies novel therapeutic targets for varicose veins

• Downloaded 264 times
• Download rankings, all-time:
  • Site-wide: 63,018 out of 100,173
  • In genetics: 3,465 out of 4,991
• Year to date:
  • Site-wide: 15,405 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

A new strategy for identifying mechanisms of drug-drug interaction using transcriptome analysis: Compound Kushen injection as a proof of principle

• Downloaded 264 times
• Download rankings, all-time:
  • Site-wide: 63,104 out of 100,173
  • In pharmacology and toxicology: 454 out of 971
• Year to date:
  • Site-wide: 96,051 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Understanding the Mechanistic Contribution of Herbal Extracts in Compound Kushen Injection with Transcriptome Analysis

• Downloaded 253 times
• Download rankings, all-time:
  • Site-wide: 64,957 out of 100,173
  • In pharmacology and toxicology: 475 out of 971
• Year to date:
  • Site-wide: 82,499 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Sulforaphane modulates microRNA expression in colon cancer cells to implicate the regulation of oncogenes CDC25A, HMGA2 and MYC

• Downloaded 249 times
• Download rankings, all-time:
  • Site-wide: 65,671 out of 100,173
  • In cancer biology: 2,158 out of 3,582
• Year to date:
  • Site-wide: 88,368 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Build a Better Bootstrap and the RAWR Shall Beat a Random Path to Your Door: Phylogenetic Support Estimation Revisited

• Downloaded 247 times
• Download rankings, all-time:
  • Site-wide: 66,112 out of 100,173
  • In bioinformatics: 6,925 out of 9,208
• Year to date:
  • Site-wide: 16,929 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Exploring the Changing Landscape of Cell-to-Cell Variation After CTCF Knockdown via Single Cell RNA-seq

• Downloaded 236 times
• Download rankings, all-time:
  • Site-wide: 68,040 out of 100,173
  • In genomics: 5,031 out of 6,213
• Year to date:
  • Site-wide: 60,290 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Role of Water Mediated Interactions in Calcium-Coupled Allostery of Calmodulin Domains

• Downloaded 229 times
• Download rankings, all-time:
  • Site-wide: 69,271 out of 100,173
  • In biochemistry: 2,207 out of 3,421
• Year to date:
  • Site-wide: 70,724 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Comparative Transcriptomes Analysis of Taenia pisiformis at Different Development Stages

• Downloaded 226 times
• Download rankings, all-time:
  • Site-wide: 69,740 out of 100,173
  • In molecular biology: 2,329 out of 3,470
• Year to date:
  • Site-wide: 75,252 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Autophagy Decreases Alveolar Epithelial Cell Injury by Suppressing the NF-κB Signaling Pathway and Regulating the Release of Inflammatory Mediators

• Downloaded 221 times
• Download rankings, all-time:
  • Site-wide: 70,670 out of 100,173
  • In cell biology: 3,645 out of 5,188
• Year to date:
  • Site-wide: 78,852 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Androgen Promotes Differentiation of PLZF+ Spermatogonia pool via Indirect Regulatory Pattern

• Downloaded 217 times
• Download rankings, all-time:
  • Site-wide: 71,386 out of 100,173
  • In developmental biology: 2,229 out of 2,997
• Year to date:
  • Site-wide: 80,714 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Thm2 interacts with paralog, Thm1, and sensitizes to Hedgehog signaling in postnatal skeletogenesis

• Downloaded 217 times
• Download rankings, all-time:
  • Site-wide: 71,413 out of 100,173
  • In developmental biology: 2,231 out of 2,997
• Year to date:
  • Site-wide: 20,335 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Latent defense response to non-pathogenic microbial factors impairs plant-rhizobacteria mutualism

• Downloaded 213 times
• Download rankings, all-time:
  • Site-wide: 72,027 out of 100,173
  • In plant biology: 2,148 out of 3,162
• Year to date:
  • Site-wide: 20,779 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Single-cell Characterization of Acute Myeloid Leukemia and its Microenvironment Following PD-1 Blockade Based Therapy

• Downloaded 205 times
• Download rankings, all-time:
  • Site-wide: 73,610 out of 100,173
  • In cancer biology: 2,440 out of 3,582
• Year to date:
  • Site-wide: 21,905 out of 100,173
• Since beginning of last month:
  • Site-wide: 866 out of 100,173

NF-κB modifies the mammalian circadian clock through interaction with the core clock protein BMAL1

• Downloaded 194 times
• Download rankings, all-time:
  • Site-wide: 75,651 out of 100,173
  • In molecular biology: 2,524 out of 3,470
• Year to date:
  • Site-wide: 23,657 out of 100,173
• Since beginning of last month:
  • Site-wide: 959 out of 100,173

Integrative analysis with expanded DNA methylation data reveals common key regulators and pathways in cancers

• Downloaded 192 times
• Download rankings, all-time:
  • Site-wide: 75,893 out of 100,173
  • In bioinformatics: 7,644 out of 9,208
• Year to date:
  • Site-wide: 93,252 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Heterodimerization of UNC-13/RIM regulates synaptic vesicle release probability but not priming

• Downloaded 191 times
• Download rankings, all-time:
  • Site-wide: 75,993 out of 100,173
  • In neuroscience: 13,612 out of 17,827
• Year to date:
  • Site-wide: 93,970 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Genetic interaction of mammalian IFT-A paralogs regulates cilia disassembly, ciliary protein trafficking, Hedgehog signaling and embryogenesis

• Downloaded 191 times
• Download rankings, all-time:
  • Site-wide: 76,040 out of 100,173
  • In genetics: 4,073 out of 4,991
• Year to date:
  • Site-wide: 62,776 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Testosterone Changes in Female Pandas in Estrus

• Downloaded 189 times
• Download rankings, all-time:
  • Site-wide: 76,400 out of 100,173
  • In zoology: 384 out of 522
• Year to date:
  • Site-wide: 50,700 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Bio-JOIE: Joint Representation Learning of Biological Knowledge Bases

• Downloaded 183 times
• Download rankings, all-time:
  • Site-wide: 77,541 out of 100,173
  • In bioinformatics: 7,735 out of 9,208
• Year to date:
  • Site-wide: 25,598 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Loss of tissue non-specific alkaline phosphatase (TNAP) enzyme activity in cerebral microvessels is coupled to persistent neuroinflammation and behavioral deficits in late sepsis

• Downloaded 177 times
• Download rankings, all-time:
  • Site-wide: 78,560 out of 100,173
  • In neuroscience: 14,060 out of 17,827
• Year to date:
  • Site-wide: 61,525 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Association between ocular biometrical parameters and diabetic retinopathy in Chinese adults with type 2 diabetes mellitus

• Downloaded 167 times
• Download rankings, all-time:
  • Site-wide: 80,186 out of 100,173
  • In pathology: 430 out of 582
• Year to date:
  • Site-wide: 28,880 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Transduction catalysis: doxorubicin accelerates and enhances rAAV-mediated gene expression in the cortex of mouse, cat and monkey

• Downloaded 160 times
• Download rankings, all-time:
  • Site-wide: 81,446 out of 100,173
  • In neuroscience: 14,576 out of 17,827
• Year to date:
  • Site-wide: 30,420 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Increased p53 signaling impairs neural differentiation causing HUWE1-promoted intellectual disabilities

• Downloaded 146 times
• Download rankings, all-time:
  • Site-wide: 83,636 out of 100,173
  • In cell biology: 4,309 out of 5,188
• Year to date:
  • Site-wide: 34,114 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Recovery of Consciousness and Cognition after General Anesthesia in Humans

• Downloaded 139 times
• Download rankings, all-time:
  • Site-wide: 84,697 out of 100,173
  • In neuroscience: 15,152 out of 17,827
• Year to date:
  • Site-wide: 36,166 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Experimental Stroke Induces Chronic Gut Dysbiosis and Neuroinflammation in Male Mice

• Downloaded 135 times
• Download rankings, all-time:
  • Site-wide: 85,283 out of 100,173
  • In neuroscience: 15,267 out of 17,827
• Year to date:
  • Site-wide: 37,481 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Intraflagellar transport-A deficiency ameliorates ADPKD renal cystogenesis in a renal tubular- and maturation-dependent manner

• Downloaded 135 times
• Download rankings, all-time:
  • Site-wide: 85,252 out of 100,173
  • In genetics: 4,468 out of 4,991
• Year to date:
  • Site-wide: 37,401 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Strain-specific genome evolution in Trypanosoma cruzi, the agent of Chagas disease

• Downloaded 124 times
• Download rankings, all-time:
  • Site-wide: 86,883 out of 100,173
  • In microbiology: 7,320 out of 8,867
• Year to date:
  • Site-wide: 41,219 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Mechanical dysfunction induced by a hypertrophic cardiomyopathy mutation is the primary driver of cellular adaptation

• Downloaded 121 times
• Download rankings, all-time:
  • Site-wide: 87,309 out of 100,173
  • In biophysics: 3,835 out of 4,409
• Year to date:
  • Site-wide: 42,320 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

The inner membrane protein YhdP modulates the rate of anterograde phospholipid flow in Escherichia coli

• Downloaded 103 times
• Download rankings, all-time:
  • Site-wide: 89,410 out of 100,173
  • In molecular biology: 3,024 out of 3,470
• Year to date:
  • Site-wide: 50,006 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

The influence of insulin therapy on measurements of optical coherence tomography parameters in diabetic patients without retinopathy

• Downloaded 98 times
• Download rankings, all-time:
  • Site-wide: 90,068 out of 100,173
  • In physiology: 1,170 out of 1,423
• Year to date:
  • Site-wide: 52,576 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Oncogenic Activation of AKT by MAPK6

• Downloaded 93 times
• Download rankings, all-time:
  • Site-wide: 90,687 out of 100,173
  • In cancer biology: 3,164 out of 3,582
• Year to date:
  • Site-wide: 55,504 out of 100,173
• Since beginning of last month:
  • Site-wide: 2,575 out of 100,173

Genome-wide identification of long non-coding RNAs in the gravid ectoparasite Varroa destructor

• Downloaded 91 times
• Download rankings, all-time:
  • Site-wide: 90,831 out of 100,173
  • In genomics: 5,882 out of 6,213
• Year to date:
  • Site-wide: 56,708 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Prediction of LncRNA Encoded Small Peptides in Glioma and The Oligomer Channel Functional Analysis Using in Silico Approaches

• Downloaded 90 times
• Download rankings, all-time:
  • Site-wide: 91,013 out of 100,173
  • In biophysics: 4,013 out of 4,409
• Year to date:
  • Site-wide: 57,166 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

Limbal Niche Cells in Three-Dimensional Matrigel Induced Dedifferentiation of Mature Corneal Epithelial Cells toward a Progenitor State

• Downloaded 56 times
• Download rankings, all-time:
  • Site-wide: 94,796 out of 100,173
  • In bioengineering: 2,168 out of 2,325
• Year to date:
  • Site-wide: 83,154 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173

IFT-A deficiency in juvenile mice impairs biliary development and exacerbates ADPKD liver disease

• Downloaded 35 times
• Download rankings, all-time:
  • Site-wide: 96,566 out of 100,173
  • In genetics: 4,879 out of 4,991
• Year to date:
  • Site-wide: 96,246 out of 100,173
• Since beginning of last month:
  • Site-wide: 5,784 out of 100,173

Effects of N-linked glycan of Lassa Virus Envelope Glycoprotein on the Immune Response

• Downloaded 33 times
• Download rankings, all-time:
  • Site-wide: 96,703 out of 100,173
  • In microbiology: 8,426 out of 8,867
• Year to date:
  • Site-wide: 96,544 out of 100,173
• Since beginning of last month:
  • Site-wide: 5,920 out of 100,173

Screening of Botanical Drugs Against Lassa Virus Entry

• Downloaded 30 times
• Download rankings, all-time:
  • Site-wide: 96,845 out of 100,173
  • In microbiology: 8,455 out of 8,867
• Year to date:
  • Site-wide: 96,762 out of 100,173
• Since beginning of last month:
  • Site-wide: None out of 100,173