Author: Wei Wang

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Preprints

Comorbidity and its impact on 1,590 patients with COVID-19 in China: A Nationwide Analysis

• Downloaded 26,355 times
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  • Site-wide: 417
  • In respiratory medicine: 4
• Year to date:
  • Site-wide: 11,488
• Since beginning of last month:
  • Site-wide: 10,881

COVID-19 in Wuhan: Immediate Psychological Impact on 5062 Health Workers

• Downloaded 11,775 times
• Download rankings, all-time:
  • Site-wide: 1,122
  • In psychiatry and clinical psychology: 6
• Year to date:
  • Site-wide: 13,027
• Since beginning of last month:
  • Site-wide: 7,870

Age profile of susceptibility, mixing, and social distancing shape the dynamics of the novel coronavirus disease 2019 outbreak in China

• Downloaded 11,232 times
• Download rankings, all-time:
  • Site-wide: 1,198
  • In epidemiology: 171
• Year to date:
  • Site-wide: 9,249
• Since beginning of last month:
  • Site-wide: 24,336

Modified TCA/acetone precipitation of plant proteins for proteomic analysis

• Downloaded 9,870 times
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  • Site-wide: 1,388
  • In biochemistry: 17
• Year to date:
  • Site-wide: 16,715
• Since beginning of last month:
  • Site-wide: 10,762

Environmental contamination of the SARS-CoV-2 in healthcare premises: An urgent call for protection for healthcare workers

• Downloaded 8,390 times
• Download rankings, all-time:
  • Site-wide: 1,727
  • In infectious diseases: 511
• Year to date:
  • Site-wide: 63,742
• Since beginning of last month:
  • Site-wide: 103,756

Global profiling of SARS-CoV-2 specific IgG/ IgM responses of convalescents using a proteome microarray

• Downloaded 6,819 times
• Download rankings, all-time:
  • Site-wide: 2,295
  • In infectious diseases: 627
• Year to date:
  • Site-wide: 48,644
• Since beginning of last month:
  • Site-wide: 66,273

Ensovibep, a novel trispecific DARPin candidate that protects against SARS-CoV-2 variants

• Downloaded 6,582 times
• Download rankings, all-time:
  • Site-wide: 2,402
  • In immunology: 100
• Year to date:
  • Site-wide: 2,551
• Since beginning of last month:
  • Site-wide: 6,930

Is Oculudentavis a bird or even archosaur?

• Downloaded 5,519 times
• Download rankings, all-time:
  • Site-wide: 3,060
  • In evolutionary biology: 38
• Year to date:
  • Site-wide: 89,701
• Since beginning of last month:
  • Site-wide: 66,074

Systematic mapping of chromatin state landscapes during mouse development

• Downloaded 5,171 times
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  • Site-wide: 3,340
  • In genomics: 290
• Year to date:
  • Site-wide: 23,614
• Since beginning of last month:
  • Site-wide: 51,992

Detection of 2019 novel coronavirus in semen and testicular biopsy specimen of COVID-19 patients

• Downloaded 5,038 times
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  • Site-wide: 3,453
  • In infectious diseases: 827
• Year to date:
  • Site-wide: 24,430
• Since beginning of last month:
  • Site-wide: 76,240

CRISPR-Cas13d induces efficient mRNA knock-down in animal embryos

• Downloaded 4,928 times
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  • Site-wide: 3,565
  • In developmental biology: 23
• Year to date:
  • Site-wide: 28,924
• Since beginning of last month:
  • Site-wide: 79,797

Evolving epidemiology of novel coronavirus diseases 2019 and possible interruption of local transmission outside Hubei Province in China: a descriptive and modeling study

• Downloaded 4,172 times
• Download rankings, all-time:
  • Site-wide: 4,506
  • In infectious diseases: 975
• Year to date:
  • Site-wide: 63,702
• Since beginning of last month:
  • Site-wide: 38,939

Infectivity, susceptibility, and risk factors associated with SARS-CoV-2 transmission under intensive contact tracing in Hunan, China

• Downloaded 3,403 times
• Download rankings, all-time:
  • Site-wide: 6,079
  • In infectious diseases: 1,177
• Year to date:
  • Site-wide: 66,390
• Since beginning of last month:
  • Site-wide: 30,181

Recurrence of cancer cell states across diverse tumors and their interactions with the microenvironment

• Downloaded 3,324 times
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  • Site-wide: 6,311
  • In cancer biology: 90
• Year to date:
  • Site-wide: 14,195
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  • Site-wide: 18,824

The Use of Adjuvant Therapy in Preventing Progression to Severe Pneumonia in Patients with Coronavirus Disease 2019: A Multicenter Data Analysis

• Downloaded 3,185 times
• Download rankings, all-time:
  • Site-wide: 6,713
  • In infectious diseases: 1,263
• Year to date:
  • Site-wide: 44,838
• Since beginning of last month:
  • Site-wide: 125,055

A single cell transcriptional roadmap for cardiopharyngeal fate diversification

• Downloaded 2,987 times
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  • Site-wide: 7,345
  • In developmental biology: 82
• Year to date:
  • Site-wide: 18,282
• Since beginning of last month:
  • Site-wide: 75,386

Early Prediction of Disease Progression in 2019 Novel Coronavirus Pneumonia Patients Outside Wuhan with CT and Clinical Characteristics

• Downloaded 2,889 times
• Download rankings, all-time:
  • Site-wide: 7,685
  • In infectious diseases: 1,371
• Year to date:
  • Site-wide: 90,938
• Since beginning of last month:
  • Site-wide: 164,680

In-Vivo Toxicity Studies and In-Vitro Inactivation of SARS-CoV-2 by Povidone-iodine In-situ Gel Forming Formulations

• Downloaded 2,709 times
• Download rankings, all-time:
  • Site-wide: 8,473
  • In microbiology: 516
• Year to date:
  • Site-wide: 11,614
• Since beginning of last month:
  • Site-wide: 52,211

GSKB: A gene set database for pathway analysis in mouse

• Downloaded 2,563 times
• Download rankings, all-time:
  • Site-wide: 9,210
  • In bioinformatics: 957
• Year to date:
  • Site-wide: 72,656
• Since beginning of last month:
  • Site-wide: 25,996

Assessment of single cell RNA-seq normalization methods

• Downloaded 2,370 times
• Download rankings, all-time:
  • Site-wide: 10,394
  • In bioinformatics: 1,106
• Year to date:
  • Site-wide: 173,789
• Since beginning of last month:
  • Site-wide: 119,358

SHP2 Inhibition Abrogates Adaptive Resistance to KRASG12C-Inhibition and Remodels the Tumor Microenvironment of KRAS-Mutant Tumors

• Downloaded 2,359 times
• Download rankings, all-time:
  • Site-wide: 10,478
  • In cancer biology: 184
• Year to date:
  • Site-wide: 36,487
• Since beginning of last month:
  • Site-wide: 11,642

Case fatality risk of novel coronavirus diseases 2019 in China

• Downloaded 2,341 times
• Download rankings, all-time:
  • Site-wide: 10,602
  • In infectious diseases: 1,639
• Year to date:
  • Site-wide: 90,870
• Since beginning of last month:
  • Site-wide: 79,914

Post-vaccination Omicron infections induce broader immunity across antigenic space than prototype mRNA COVID-19 booster vaccination or primary infection

• Downloaded 2,152 times
• Download rankings, all-time:
  • Site-wide: 12,037
  • In microbiology: 735
• Year to date:
  • Site-wide: 6,157
• Since beginning of last month:
  • Site-wide: 8,912

Persistent SARS-CoV-2 presence is companied with defects in adaptive immune system in non-severe COVID-19 patients

• Downloaded 2,021 times
• Download rankings, all-time:
  • Site-wide: 13,221
  • In infectious diseases: 1,855
• Year to date:
  • Site-wide: 80,764
• Since beginning of last month:
  • Site-wide: 164,845

Establishment In Culture Of Expanded Potential Stem Cells

• Downloaded 1,929 times
• Download rankings, all-time:
  • Site-wide: 14,194
  • In developmental biology: 191
• Year to date:
  • Site-wide: 163,180
• Since beginning of last month:
  • Site-wide: 203,952

Mitochondrial phenotypes in purified human immune cell subtypes and cell mixtures

• Downloaded 1,894 times
• Download rankings, all-time:
  • Site-wide: 14,594
  • In cell biology: 388
• Year to date:
  • Site-wide: 19,758
• Since beginning of last month:
  • Site-wide: 79,313

Role of short-chain fatty acids in the gut-brain axis in schizophrenia: contribution to immune activation and pathophysiology in humans and mice

• Downloaded 1,855 times
• Download rankings, all-time:
  • Site-wide: 15,097
  • In neuroscience: 1,614
• Year to date:
  • Site-wide: 29,444
• Since beginning of last month:
  • Site-wide: 46,117

Spatially clustered loci with multiple enhancers are frequent targets of HIV-1

• Downloaded 1,823 times
• Download rankings, all-time:
  • Site-wide: 15,516
  • In genomics: 1,397
• Year to date:
  • Site-wide: 132,199
• Since beginning of last month:
  • Site-wide: 174,677

Identification of protein aggregates in the aging vertebrate brain with prion-like andphase separation properties

• Downloaded 1,737 times
• Download rankings, all-time:
  • Site-wide: 16,702
  • In neuroscience: 1,985
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 3,947

Interferon alpha-based combinations suppress SARS-CoV-2 infection in vitro and in vivo

• Downloaded 1,694 times
• Download rankings, all-time:
  • Site-wide: 17,348
  • In microbiology: 1,017
• Year to date:
  • Site-wide: 185,826
• Since beginning of last month:
  • Site-wide: 55,034

The Effectiveness of China’s National Forest Protection Program and National-level Nature Reserves, 2000 to 2010

• Downloaded 1,662 times
• Download rankings, all-time:
  • Site-wide: 17,895
  • In ecology: 239
• Year to date:
  • Site-wide: 133,840
• Since beginning of last month:
  • Site-wide: 91,229

Identification of DNA motifs that regulate DNA methylation

• Downloaded 1,604 times
• Download rankings, all-time:
  • Site-wide: 18,930
  • In bioinformatics: 2,094
• Year to date:
  • Site-wide: 20,489
• Since beginning of last month:
  • Site-wide: 59,675

Single-cell transcriptome profiling of the Ciona larval brain

• Downloaded 1,494 times
• Download rankings, all-time:
  • Site-wide: 21,187
  • In developmental biology: 335
• Year to date:
  • Site-wide: 92,490
• Since beginning of last month:
  • Site-wide: 118,979

Cardiac Structural and Functional Characteristics in Patients with Coronavirus Disease 2019: A Serial Echocardiographic Study

• Downloaded 1,390 times
• Download rankings, all-time:
  • Site-wide: 23,812
  • In cardiovascular medicine: 46
• Year to date:
  • Site-wide: 47,033
• Since beginning of last month:
  • Site-wide: 34,412

Association of Personal Protective Equipment Use with Successful Protection Against COVID-19 Infection Among Health Care Workers

• Downloaded 1,302 times
• Download rankings, all-time:
  • Site-wide: 26,475
  • In epidemiology: 1,576
• Year to date:
  • Site-wide: 63,585
• Since beginning of last month:
  • Site-wide: 54,601

Symptom-level genetic modelling identifies novel risk loci and unravels the shared genetic architecture of anxiety and depression

• Downloaded 1,251 times
• Download rankings, all-time:
  • Site-wide: 28,186
  • In genetic and genomic medicine: 170
• Year to date:
  • Site-wide: 29,342
• Since beginning of last month:
  • Site-wide: 27,136

Assessing the measurement transfer function of single-cell RNA sequencing

• Downloaded 1,225 times
• Download rankings, all-time:
  • Site-wide: 29,098
  • In genomics: 2,442
• Year to date:
  • Site-wide: 168,927
• Since beginning of last month:
  • Site-wide: 198,722

TahcoRoll: An Efficient Approach for Signature Profiling in Genomic Data through Variable-Length k-mers

• Downloaded 1,222 times
• Download rankings, all-time:
  • Site-wide: 29,197
  • In bioinformatics: 3,109
• Year to date:
  • Site-wide: 131,811
• Since beginning of last month:
  • Site-wide: 204,621

Large-scale trans-ethnic replication and discovery of genetic associations for rare diseases with self-reported medical data

• Downloaded 1,220 times
• Download rankings, all-time:
  • Site-wide: 29,281
  • In genetic and genomic medicine: 179
• Year to date:
  • Site-wide: 100,644
• Since beginning of last month:
  • Site-wide: 15,869

Finding de novo methylated DNA motifs

• Downloaded 1,200 times
• Download rankings, all-time:
  • Site-wide: 30,042
  • In bioinformatics: 3,201
• Year to date:
  • Site-wide: 96,607
• Since beginning of last month:
  • Site-wide: 145,889

Hybrid origins and the earliest stages of diploidization in the highly successful recent polyploid Capsella bursa-pastoris

• Downloaded 1,189 times
• Download rankings, all-time:
  • Site-wide: 30,490
  • In evolutionary biology: 1,097
• Year to date:
  • Site-wide: 93,727
• Since beginning of last month:
  • Site-wide: 208,319

Loss of SATB1 Induces a p21 Dependent Cellular Senescence Phenotype in Dopaminergic Neurons

• Downloaded 1,163 times
• Download rankings, all-time:
  • Site-wide: 31,591
  • In neuroscience: 3,926
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 116,181

Parallel Characterization of cis-Regulatory Elements for Multiple Genes Using CRISPRpath

• Downloaded 1,162 times
• Download rankings, all-time:
  • Site-wide: 31,657
  • In genomics: 2,619
• Year to date:
  • Site-wide: 161,891
• Since beginning of last month:
  • Site-wide: 71,057

Keystone species determine the productivity of synthetic microbial biofilm communities

• Downloaded 1,161 times
• Download rankings, all-time:
  • Site-wide: 31,668
  • In microbiology: 2,103
• Year to date:
  • Site-wide: 104,656
• Since beginning of last month:
  • Site-wide: 6,688

Identification of gut microbiome markers for schizophrenia delineates a potential role of Streptococcus

• Downloaded 1,151 times
• Download rankings, all-time:
  • Site-wide: 32,140
  • In microbiology: 1,856
• Year to date:
  • Site-wide: 140,405
• Since beginning of last month:
  • Site-wide: 126,615

Molecular Crowding Tunes Material States of Ribonucleoprotein Condensates

• Downloaded 1,120 times
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  • Site-wide: 33,510
  • In biophysics: 983
• Year to date:
  • Site-wide: 70,343
• Since beginning of last month:
  • Site-wide: 153,677

The RNA-binding ATPase, Armitage, Couples piRNA Amplification in Nuage to Phased piRNA Production on Mitochondria

• Downloaded 1,101 times
• Download rankings, all-time:
  • Site-wide: 34,364
  • In genetics: 1,368
• Year to date:
  • Site-wide: 74,047
• Since beginning of last month:
  • Site-wide: 151,919

Hiplot: a comprehensive and easy-to-use web service boosting publication-ready biomedical data visualization

• Downloaded 1,100 times
• Download rankings, all-time:
  • Site-wide: 34,409
  • In bioinformatics: 3,870
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 9,884

Association of 25 hydroxyvitamin D concentration with risk of COVID-19: a Mendelian randomization study

• Downloaded 1,092 times
• Download rankings, all-time:
  • Site-wide: 34,792
  • In infectious diseases: 3,105
• Year to date:
  • Site-wide: 46,615
• Since beginning of last month:
  • Site-wide: 65,994

A nuclear hormone receptor and lipid metabolism axis are required for the maintenance and regeneration of reproductive organs

• Downloaded 1,072 times
• Download rankings, all-time:
  • Site-wide: 35,802
  • In developmental biology: 694
• Year to date:
  • Site-wide: 41,217
• Since beginning of last month:
  • Site-wide: 61,351

Global, regional, and national estimates of target population sizes for COVID-19 vaccination

• Downloaded 1,047 times
• Download rankings, all-time:
  • Site-wide: 37,151
  • In infectious diseases: 3,224
• Year to date:
  • Site-wide: 48,309
• Since beginning of last month:
  • Site-wide: 71,851

Co-expression enrichment analysis at the single-cell level reveals convergent defects in neural progenitor cells and their cell-type transitions in neurodevelopmental disorders

• Downloaded 976 times
• Download rankings, all-time:
  • Site-wide: 41,391
  • In genetics: 1,639
• Year to date:
  • Site-wide: 90,518
• Since beginning of last month:
  • Site-wide: 215,059

Linear epitopes of SARS-CoV-2 spike protein elicit neutralizing antibodies in COVID-19 patients

• Downloaded 967 times
• Download rankings, all-time:
  • Site-wide: 42,005
  • In infectious diseases: 3,445
• Year to date:
  • Site-wide: 125,112
• Since beginning of last month:
  • Site-wide: 79,638

Contemporary circulating enterovirus D68 strains show differential viral entry and replication in human neuronal cells

• Downloaded 964 times
• Download rankings, all-time:
  • Site-wide: 42,210
  • In microbiology: 2,486
• Year to date:
  • Site-wide: 61,517
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  • Site-wide: 38,148

Single-cell Characterization of Acute Myeloid Leukemia and its Microenvironment Following PD-1 Blockade Based Therapy

• Downloaded 954 times
• Download rankings, all-time:
  • Site-wide: 42,866
  • In cancer biology: 1,214
• Year to date:
  • Site-wide: 45,393
• Since beginning of last month:
  • Site-wide: 54,881

Full-genome evolutionary histories of selfing, splitting and selection in Caenorhabditis

• Downloaded 935 times
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  • Site-wide: 44,215
  • In genomics: 3,340
• Year to date:
  • Site-wide: 192,119
• Since beginning of last month:
  • Site-wide: 175,008

Computational Study of Ions and Water Permeation and Transportation Mechanisms of the SARS-CoV-2 Pentameric E Protein Channel

• Downloaded 904 times
• Download rankings, all-time:
  • Site-wide: 46,553
  • In biophysics: 1,446
• Year to date:
  • Site-wide: 156,171
• Since beginning of last month:
  • Site-wide: 189,324

An FGF-driven feed-forward circuit patterns the cardiopharyngeal mesoderm in space and time

• Downloaded 903 times
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  • Site-wide: 46,711
  • In developmental biology: 965
• Year to date:
  • Site-wide: 189,609
• Since beginning of last month:
  • Site-wide: 177,659

Single cell multi-omic analysis identifies a Tbx1-dependent multilineage primed population in the murine cardiopharyngeal mesoderm

• Downloaded 887 times
• Download rankings, all-time:
  • Site-wide: 48,058
  • In developmental biology: 1,018
• Year to date:
  • Site-wide: 185,763
• Since beginning of last month:
  • Site-wide: 171,752

Paralogues of the PXY and ER receptor kinases enforce radial patterning in plant vascular tissue.

• Downloaded 872 times
• Download rankings, all-time:
  • Site-wide: 49,257
  • In plant biology: 993
• Year to date:
  • Site-wide: 40,915
• Since beginning of last month:
  • Site-wide: 61,244

Molecular evolution across developmental time reveals rapid divergence in early embryogenesis

• Downloaded 869 times
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  • Site-wide: 49,514
  • In evolutionary biology: 2,028
• Year to date:
  • Site-wide: 167,996
• Since beginning of last month:
  • Site-wide: 116,911

Motto: Representing motifs in consensus sequences with minimum information loss

• Downloaded 846 times
• Download rankings, all-time:
  • Site-wide: 51,670
  • In bioinformatics: 5,173
• Year to date:
  • Site-wide: 168,808
• Since beginning of last month:
  • Site-wide: 119,152

MiniScrub: de novo long read scrubbing using approximate alignment and deep learning

• Downloaded 838 times
• Download rankings, all-time:
  • Site-wide: 52,386
  • In bioinformatics: 5,209
• Year to date:
  • Site-wide: 136,137
• Since beginning of last month:
  • Site-wide: 153,750

NF-κB modifies the mammalian circadian clock through interaction with the core clock protein BMAL1

• Downloaded 820 times
• Download rankings, all-time:
  • Site-wide: 54,059
  • In molecular biology: 1,575
• Year to date:
  • Site-wide: 14,877
• Since beginning of last month:
  • Site-wide: 76,785

Systems-level identification of transcription factors critical for mouse embryonic development

• Downloaded 816 times
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  • Site-wide: 54,479
  • In bioinformatics: 5,349
• Year to date:
  • Site-wide: None
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  • Site-wide: 203,419

Systematic identification of cooperation between DNA binding proteins in 3D space

• Downloaded 804 times
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  • Site-wide: 55,719
  • In bioinformatics: 5,470
• Year to date:
  • Site-wide: 118,627
• Since beginning of last month:
  • Site-wide: 207,740

Lasagna: Multifaceted Protein-Protein Interaction Prediction Based on Siamese Residual RCNN

• Downloaded 802 times
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  • Site-wide: 55,920
  • In bioinformatics: 5,498
• Year to date:
  • Site-wide: 137,010
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  • Site-wide: 180,459

Genome-wide association analysis and replication in 810,625 individuals identifies novel therapeutic targets for varicose veins

• Downloaded 783 times
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  • Site-wide: 57,810
  • In genetics: 2,271
• Year to date:
  • Site-wide: 37,793
• Since beginning of last month:
  • Site-wide: 78,186

Genome structure predicts modular transcriptome responses to genetic and environmental conditions

• Downloaded 766 times
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  • Site-wide: 59,874
  • In genomics: 4,226
• Year to date:
  • Site-wide: 61,740
• Since beginning of last month:
  • Site-wide: 116,897

Association between Alzheimer's disease and COVID-19: A bidirectional Mendelian randomization

• Downloaded 765 times
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  • Site-wide: 59,914
  • In genetic and genomic medicine: 383
• Year to date:
  • Site-wide: 66,333
• Since beginning of last month:
  • Site-wide: 64,885

Prophase removal of chromosome-associated RNAs facilitates anaphase chromosome segregation

• Downloaded 760 times
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  • Site-wide: 60,486
  • In cell biology: 2,584
• Year to date:
  • Site-wide: 61,099
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  • Site-wide: 184,271

Genome-wide study identifies association between HLA-B*55:01 and penicillin allergy

• Downloaded 739 times
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  • Site-wide: 63,062
  • In genetics: 2,438
• Year to date:
  • Site-wide: 120,387
• Since beginning of last month:
  • Site-wide: 161,998

Neurogenin regulates effectors of migratory neuron cell behaviors in Ciona

• Downloaded 736 times
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  • Site-wide: 63,510
  • In developmental biology: 1,489
• Year to date:
  • Site-wide: 113,470
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  • Site-wide: 75,438

JEDI: Circular RNA Prediction based on Junction Encoders and Deep Interaction among Splice Sites

• Downloaded 735 times
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  • Site-wide: 63,543
  • In bioinformatics: 6,071
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 162,921

Interplay Between Short-range Attraction and Long-range Repulsion Controls Reentrant Liquid Condensation of Ribonucleoprotein-RNA Complexes

• Downloaded 722 times
• Download rankings, all-time:
  • Site-wide: 65,218
  • In biophysics: 2,172
• Year to date:
  • Site-wide: 111,950
• Since beginning of last month:
  • Site-wide: 119,348

Global variability of the human IgG glycome

• Downloaded 704 times
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  • Site-wide: 67,621
  • In biochemistry: 1,810
• Year to date:
  • Site-wide: 113,310
• Since beginning of last month:
  • Site-wide: 93,205

Mechanisms of integrin αVβ5 clustering in flat clathrin lattices

• Downloaded 693 times
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  • Site-wide: 69,230
  • In cell biology: 3,018
• Year to date:
  • Site-wide: 114,016
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  • Site-wide: 201,226

Nationwide population genetic screening improves outcomes of newborn screening for hearing loss in China

• Downloaded 680 times
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  • Site-wide: 70,952
  • In genetics: 2,719
• Year to date:
  • Site-wide: 168,360
• Since beginning of last month:
  • Site-wide: 199,628

Experimental Stroke Induces Chronic Gut Dysbiosis and Neuroinflammation in Male Mice

• Downloaded 678 times
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  • Site-wide: 71,253
  • In neuroscience: 10,107
• Year to date:
  • Site-wide: 37,576
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  • Site-wide: 101,148

Fecal microbiota as a non-invasive biomarker to predict the tissue iron accumulation in intestine epithelial cells and liver

• Downloaded 669 times
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  • Site-wide: 72,599
  • In microbiology: 4,548
• Year to date:
  • Site-wide: 40,675
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  • Site-wide: 74,906

Genome of the estuarine oyster provides insights into climate impact and adaptive plasticity

• Downloaded 639 times
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  • Site-wide: 77,213
  • In evolutionary biology: 3,465
• Year to date:
  • Site-wide: 104,523
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  • Site-wide: 85,418

Identification of 67 pleiotropic genes for seven autoimmune diseases using multivariate statistical analysis

• Downloaded 635 times
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  • Site-wide: 77,792
  • In genetics: 2,988
• Year to date:
  • Site-wide: 70,790
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  • Site-wide: 153,902

Optimized Quantification of Intrahost Viral Diversity in SARS-CoV-2 and Influenza Virus Sequence Data

• Downloaded 633 times
• Download rankings, all-time:
  • Site-wide: 78,079
  • In microbiology: 5,104
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 22,481

Bacterial Glycogen as a Durable Energy Reserve Contributing to Persistence: An Updated Bibliography and Mathematical Model

• Downloaded 628 times
• Download rankings, all-time:
  • Site-wide: 78,939
  • In microbiology: 4,951
• Year to date:
  • Site-wide: 49,978
• Since beginning of last month:
  • Site-wide: 93,327

Xist Intron 1 Repression by TALE Transcriptional Factor Improves Somatic Cell Reprogamming in Mice

• Downloaded 624 times
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  • Site-wide: 79,612
  • In developmental biology: 1,960
• Year to date:
  • Site-wide: 163,302
• Since beginning of last month:
  • Site-wide: 146,501

Spontaneous dormancy protects Trypanosoma cruzi during extended drug exposure

• Downloaded 622 times
• Download rankings, all-time:
  • Site-wide: 79,918
  • In microbiology: 4,979
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 142,805

Cell Cycle, Energy Metabolism and DNA Repair Pathways in Cancer Cells are Suppressed by Compound Kushen Injection.

• Downloaded 615 times
• Download rankings, all-time:
  • Site-wide: 81,119
  • In cancer biology: 2,370
• Year to date:
  • Site-wide: 191,746
• Since beginning of last month:
  • Site-wide: 177,158

Chemical, physical and biological triggers of Bcl-xL-mediated apoptosis

• Downloaded 607 times
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  • Site-wide: 82,387
  • In cancer biology: 2,437
• Year to date:
  • Site-wide: 154,595
• Since beginning of last month:
  • Site-wide: 121,042

Lactate receptor HCAR1 regulates neurogenesis and microglia activation after neonatal hypoxia-ischemia

• Downloaded 599 times
• Download rankings, all-time:
  • Site-wide: 83,878
  • In neuroscience: 12,279
• Year to date:
  • Site-wide: 85,777
• Since beginning of last month:
  • Site-wide: 26,346

Systematic profiling of SARS-CoV-2 specific IgG epitopes at single amino acid resolution

• Downloaded 588 times
• Download rankings, all-time:
  • Site-wide: 85,848
  • In epidemiology: 3,794
• Year to date:
  • Site-wide: 125,692
• Since beginning of last month:
  • Site-wide: 70,864

NEIL1 and NEIL2 DNA glycosylases regulate anxiety and learning in a cooperative manner

• Downloaded 582 times
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  • Site-wide: 86,967
  • In molecular biology: 2,528
• Year to date:
  • Site-wide: 65,443
• Since beginning of last month:
  • Site-wide: 95,955

Role of Water-bridged Interactions in Metal Ion Coupled Protein Allostery

• Downloaded 580 times
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  • Site-wide: 87,386
  • In biochemistry: 2,413
• Year to date:
  • Site-wide: 118,677
• Since beginning of last month:
  • Site-wide: 149,264

Non-parametric and semi-parametric support estimation using SEquential RESampling random walks on biomolecular sequences

• Downloaded 573 times
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  • Site-wide: 88,801
  • In bioinformatics: 7,925
• Year to date:
  • Site-wide: 92,645
• Since beginning of last month:
  • Site-wide: 173,860

Cell cycle-gated feedback control mediates desensitization to interferon stimulation

• Downloaded 562 times
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  • Site-wide: 90,856
  • In systems biology: 1,871
• Year to date:
  • Site-wide: 121,546
• Since beginning of last month:
  • Site-wide: 122,194

DTI-CDF: a CDF model towards the prediction of DTIs based on hybrid features

• Downloaded 560 times
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  • Site-wide: 91,243
  • In bioinformatics: 8,223
• Year to date:
  • Site-wide: 49,518
• Since beginning of last month:
  • Site-wide: 117,991

Build a Better Bootstrap and the RAWR Shall Beat a Random Path to Your Door: Phylogenetic Support Estimation Revisited

• Downloaded 556 times
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  • Site-wide: 92,069
  • In bioinformatics: 8,125
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 213,738

The Effect of Compound Kushen Injection on Cancer Cells: Integrated Identification of Candidate Molecular Mechanisms.

• Downloaded 550 times
• Download rankings, all-time:
  • Site-wide: 93,370
  • In pharmacology and toxicology: 605
• Year to date:
  • Site-wide: 137,064
• Since beginning of last month:
  • Site-wide: 146,734

Targeted mutations on 3D hub loci alter spatial interaction environment

• Downloaded 543 times
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  • Site-wide: 94,793
  • In biophysics: 3,397
• Year to date:
  • Site-wide: 171,558
• Since beginning of last month:
  • Site-wide: 201,906

Mutation effect estimation on protein-protein interactions using deep contextualized representation learning

• Downloaded 542 times
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  • Site-wide: 94,936
  • In bioinformatics: 8,330
• Year to date:
  • Site-wide: 141,552
• Since beginning of last month:
  • Site-wide: 187,264

Bio-JOIE: Joint Representation Learning of Biological Knowledge Bases

• Downloaded 540 times
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  • Site-wide: 95,347
  • In bioinformatics: 8,420
• Year to date:
  • Site-wide: 159,928
• Since beginning of last month:
  • Site-wide: 104,131

Screening of FDA-approved Drugs and Identification of Novel Lassa Virus Entry Inhibitors

• Downloaded 535 times
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  • Site-wide: 96,472
  • In microbiology: 6,130
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 154,610

A multiethnic GWAS meta-analysis of 585,243 individuals identifies new risk loci associated with cataract and reveals sex-specific effects

• Downloaded 535 times
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  • Site-wide: 96,336
  • In genetic and genomic medicine: 623
• Year to date:
  • Site-wide: 44,589
• Since beginning of last month:
  • Site-wide: 112,077

Association between ocular biometrical parameters and diabetic retinopathy in Chinese adults with type 2 diabetes mellitus

• Downloaded 529 times
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  • Site-wide: 97,639
  • In pathology: 482
• Year to date:
  • Site-wide: 44,637
• Since beginning of last month:
  • Site-wide: 65,667

Surfaceome CRISPR Screen Identifies OLFML3 as a Rhinovirus-inducible IFN Antagonist

• Downloaded 528 times
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  • Site-wide: 97,837
  • In molecular biology: 2,869
• Year to date:
  • Site-wide: 91,348
• Since beginning of last month:
  • Site-wide: 131,610

Loss of Dnmt3a dependent methylation in inhibitory neurons impairs neural function through a mechanism that impacts Rett syndrome

• Downloaded 512 times
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  • Site-wide: 101,475
  • In neuroscience: 14,660
• Year to date:
  • Site-wide: 116,186
• Since beginning of last month:
  • Site-wide: 184,493

Latent defense response to non-pathogenic microbial factors impairs plant-rhizobacteria mutualism

• Downloaded 508 times
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  • Site-wide: 102,439
  • In plant biology: 2,667
• Year to date:
  • Site-wide: 64,498
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  • Site-wide: 211,400

Uncovering Medical Insights from Vast Amounts of Biomedical Data in Clinical Case Reports

• Downloaded 503 times
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  • Site-wide: 103,482
  • In bioinformatics: 8,888
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 174,109

Strain-specific genome evolution in Trypanosoma cruzi, the agent of Chagas disease

• Downloaded 500 times
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  • Site-wide: 104,290
  • In microbiology: 6,929
• Year to date:
  • Site-wide: 48,400
• Since beginning of last month:
  • Site-wide: 77,988

Recovery of Consciousness and Cognition after General Anesthesia in Humans

• Downloaded 500 times
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  • Site-wide: 104,315
  • In neuroscience: 15,219
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 100,803

Dual functions of Discoidin domain receptor coordinate cell-matrix adhesion and collective polarity in migratory cardiopharyngeal progenitors

• Downloaded 483 times
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  • Site-wide: 108,327
  • In developmental biology: 2,836
• Year to date:
  • Site-wide: 92,635
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  • Site-wide: 151,904

The proto-oncogene DEK regulates neuronal excitability and tau accumulation in Alzheimer's disease vulnerable neurons

• Downloaded 477 times
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  • Site-wide: 109,598
  • In neuroscience: 16,643
• Year to date:
  • Site-wide: 16,140
• Since beginning of last month:
  • Site-wide: 18,704

Contextual Regression: An Accurate and Conveniently Interpretable Nonlinear Model for Mining Discovery from Scientific Data

• Downloaded 467 times
• Download rankings, all-time:
  • Site-wide: 112,037
  • In bioinformatics: 9,443
• Year to date:
  • Site-wide: 114,049
• Since beginning of last month:
  • Site-wide: 174,063

Screening of Botanical Drugs against SARS-CoV-2 Entry

• Downloaded 466 times
• Download rankings, all-time:
  • Site-wide: 112,320
  • In microbiology: 7,485
• Year to date:
  • Site-wide: 78,092
• Since beginning of last month:
  • Site-wide: 112,871

Association of Retinal Age Gap with Arterial Stiffness and Incident Cardiovascular Disease

• Downloaded 463 times
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  • Site-wide: 113,204
  • In cardiovascular medicine: 304
• Year to date:
  • Site-wide: 54,933
• Since beginning of last month:
  • Site-wide: 49,081

Genome-wide analysis identifies cis-acting elements regulating mRNA polyadenylation and translation during vertebrate oocyte maturation

• Downloaded 451 times
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  • Site-wide: 116,166
  • In genomics: 6,668
• Year to date:
  • Site-wide: 193,462
• Since beginning of last month:
  • Site-wide: 199,216

The Report on China-Spain Joint Clinical Testing for Rapid COVID-19 Risk Screening by Eye-region Manifestations

• Downloaded 445 times
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  • Site-wide: 117,571
  • In ophthalmology: 116
• Year to date:
  • Site-wide: 58,999
• Since beginning of last month:
  • Site-wide: 57,213

Human Cytomegalovirus Immediate-Early 1 Protein Causes Loss of SOX2 from Neural Progenitor Cells by Trapping Unphosphorylated STAT3 in the Nucleus

• Downloaded 441 times
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  • Site-wide: 118,835
  • In microbiology: 7,875
• Year to date:
  • Site-wide: 164,995
• Since beginning of last month:
  • Site-wide: 173,665

Structural basis for transfer RNA mimicry by a bacterial Y RNA

• Downloaded 435 times
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  • Site-wide: 120,319
  • In biochemistry: 3,533
• Year to date:
  • Site-wide: 117,387
• Since beginning of last month:
  • Site-wide: 142,705

Causal associations between COVID-19 and Atrial Fibrillation: A bidirectional Mendelian randomization study

• Downloaded 434 times
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  • Site-wide: 120,583
  • In genetic and genomic medicine: 815
• Year to date:
  • Site-wide: 125,552
• Since beginning of last month:
  • Site-wide: 94,510

Efficacy and Acceptability Comparisons of Cognitive Behavior Therapy, Drugs, and Their Combination for Panic Disorder in Adults: a Network Meta-analysis

• Downloaded 434 times
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  • Site-wide: 120,497
  • In psychiatry and clinical psychology: 673
• Year to date:
  • Site-wide: 81,257
• Since beginning of last month:
  • Site-wide: 164,697

Multiplexed promoter and gene editing in wheat using the virus-based guide RNA delivery system

• Downloaded 427 times
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  • Site-wide: 122,569
  • In genetics: 4,660
• Year to date:
  • Site-wide: 42,031
• Since beginning of last month:
  • Site-wide: 139,633

A universal approach for integrating super large-scale single-cell transcriptomes by exploring gene rankings

• Downloaded 426 times
• Download rankings, all-time:
  • Site-wide: 122,702
  • In bioinformatics: 10,156
• Year to date:
  • Site-wide: 75,920
• Since beginning of last month:
  • Site-wide: 61,960

Generative pretraining from large-scale transcriptomes: Implications for single-cell deciphering and clinical translation

• Downloaded 421 times
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  • Site-wide: 124,165
  • In bioinformatics: 10,341
• Year to date:
  • Site-wide: 108,292
• Since beginning of last month:
  • Site-wide: 46,512

An Analysis of Outbreak Dynamics and Intervention Effects for COVID-19 Transmission in Europe

• Downloaded 420 times
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  • Site-wide: 124,244
  • In infectious diseases: 6,156
• Year to date:
  • Site-wide: 89,867
• Since beginning of last month:
  • Site-wide: 129,230

Chinese medicine (Q-14) in the Treatment of Patients with Coronavirus Disease 2019 (COVID-19): A Single-center, Open label, Randomised Controlled Trial

• Downloaded 406 times
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  • Site-wide: 128,069
  • In infectious diseases: 6,292
• Year to date:
  • Site-wide: 84,308
• Since beginning of last month:
  • Site-wide: 115,828

Comparative Transcriptomes Analysis of Taenia pisiformis at Different Development Stages

• Downloaded 406 times
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  • Site-wide: 128,241
  • In molecular biology: 3,754
• Year to date:
  • Site-wide: 168,933
• Since beginning of last month:
  • Site-wide: 199,971

Testosterone Changes in Female Pandas in Estrus

• Downloaded 405 times
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  • Site-wide: 128,477
  • In zoology: 464
• Year to date:
  • Site-wide: 115,243
• Since beginning of last month:
  • Site-wide: 190,784

Sulforaphane modulates microRNA expression in colon cancer cells to implicate the regulation of oncogenes CDC25A, HMGA2 and MYC

• Downloaded 398 times
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  • Site-wide: 130,446
  • In cancer biology: 3,970
• Year to date:
  • Site-wide: 134,221
• Since beginning of last month:
  • Site-wide: 150,586

The inner membrane protein YhdP modulates the rate of anterograde phospholipid flow in Escherichia coli

• Downloaded 394 times
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  • Site-wide: 131,740
  • In molecular biology: 3,873
• Year to date:
  • Site-wide: 184,365
• Since beginning of last month:
  • Site-wide: 102,940

Understanding the Mechanistic Contribution of Herbal Extracts in Compound Kushen Injection with Transcriptome Analysis

• Downloaded 382 times
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  • Site-wide: 135,320
  • In pharmacology and toxicology: 989
• Year to date:
  • Site-wide: 187,639
• Since beginning of last month:
  • Site-wide: 203,036

Exploring the Changing Landscape of Cell-to-Cell Variation After CTCF Knockdown via Single Cell RNA-seq

• Downloaded 377 times
• Download rankings, all-time:
  • Site-wide: 136,778
  • In genomics: 7,375
• Year to date:
  • Site-wide: 163,440
• Since beginning of last month:
  • Site-wide: 102,576

Systems-level identification of key transcription factors in immune cell specification

• Downloaded 372 times
• Download rankings, all-time:
  • Site-wide: 138,124
  • In systems biology: 2,937
• Year to date:
  • Site-wide: 102,883
• Since beginning of last month:
  • Site-wide: 15,459

RNAi screening reveals requirement for PDGFRβ in JEV infection.

• Downloaded 365 times
• Download rankings, all-time:
  • Site-wide: 140,397
  • In microbiology: 9,722
• Year to date:
  • Site-wide: 127,064
• Since beginning of last month:
  • Site-wide: 54,909

Loss-of-function mutation in human Oxidation Resistance gene 1 disrupts the spatial-temporal regulation of histone arginine methylation in early brain development

• Downloaded 363 times
• Download rankings, all-time:
  • Site-wide: 140,774
  • In pathology: 822
• Year to date:
  • Site-wide: 12,518
• Since beginning of last month:
  • Site-wide: 19,353

Impact of Retinopathy and Systemic Vascular Comorbidities on All-Cause Mortality

• Downloaded 358 times
• Download rankings, all-time:
  • Site-wide: 142,272
  • In ophthalmology: 156
• Year to date:
  • Site-wide: 154,267
• Since beginning of last month:
  • Site-wide: 115,416

Deeply conserved super-enhancers maintain stem cell pluripotency in placental mammals

• Downloaded 356 times
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  • Site-wide: 142,958
  • In cell biology: 6,786
• Year to date:
  • Site-wide: 175,751
• Since beginning of last month:
  • Site-wide: 36,222

Autophagy Decreases Alveolar Epithelial Cell Injury by Suppressing the NF-κB Signaling Pathway and Regulating the Release of Inflammatory Mediators

• Downloaded 355 times
• Download rankings, all-time:
  • Site-wide: 143,325
  • In cell biology: 6,658
• Year to date:
  • Site-wide: 163,810
• Since beginning of last month:
  • Site-wide: 90,793

Mechanical dysfunction induced by a hypertrophic cardiomyopathy mutation is the primary driver of cellular adaptation

• Downloaded 349 times
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  • Site-wide: 145,082
  • In biophysics: 5,545
• Year to date:
  • Site-wide: 64,632
• Since beginning of last month:
  • Site-wide: 166,298

Androgen Promotes Differentiation of PLZF+ Spermatogonia pool via Indirect Regulatory Pattern

• Downloaded 347 times
• Download rankings, all-time:
  • Site-wide: 145,615
  • In developmental biology: 3,854
• Year to date:
  • Site-wide: 163,330
• Since beginning of last month:
  • Site-wide: 204,064

A new strategy for identifying mechanisms of drug-drug interaction using transcriptome analysis: Compound Kushen injection as a proof of principle

• Downloaded 344 times
• Download rankings, all-time:
  • Site-wide: 146,558
  • In pharmacology and toxicology: 1,093
• Year to date:
  • Site-wide: 168,186
• Since beginning of last month:
  • Site-wide: 207,986

Striatal Mu-Opioid Receptor Activation Triggers Direct-Pathway GABAergic Plasticity to Induce Negative Affect

• Downloaded 339 times
• Download rankings, all-time:
  • Site-wide: 148,086
  • In neuroscience: 22,594
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 20,908

Loss of tissue non-specific alkaline phosphatase (TNAP) enzyme activity in cerebral microvessels is coupled to persistent neuroinflammation and behavioral deficits in late sepsis

• Downloaded 336 times
• Download rankings, all-time:
  • Site-wide: 149,294
  • In neuroscience: 21,778
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 183,301

Thm2 interacts with paralog, Thm1, and sensitizes to Hedgehog signaling in postnatal skeletogenesis

• Downloaded 334 times
• Download rankings, all-time:
  • Site-wide: 149,803
  • In developmental biology: 3,989
• Year to date:
  • Site-wide: 79,939
• Since beginning of last month:
  • Site-wide: 163,133

Increased p53 signaling impairs neural differentiation causing HUWE1-promoted intellectual disabilities

• Downloaded 329 times
• Download rankings, all-time:
  • Site-wide: 151,298
  • In cell biology: 7,059
• Year to date:
  • Site-wide: 156,868
• Since beginning of last month:
  • Site-wide: 78,473

Genetic interaction of mammalian IFT-A paralogs regulates cilia disassembly, ciliary protein trafficking, Hedgehog signaling and embryogenesis

• Downloaded 326 times
• Download rankings, all-time:
  • Site-wide: 152,150
  • In genetics: 5,665
• Year to date:
  • Site-wide: 114,490
• Since beginning of last month:
  • Site-wide: 192,827

Heterodimerization of UNC-13/RIM regulates synaptic vesicle release probability but not priming

• Downloaded 322 times
• Download rankings, all-time:
  • Site-wide: 153,427
  • In neuroscience: 22,497
• Year to date:
  • Site-wide: 116,513
• Since beginning of last month:
  • Site-wide: 150,602

Oncogenic Activation of AKT by MAPK6

• Downloaded 321 times
• Download rankings, all-time:
  • Site-wide: 153,652
  • In cancer biology: 4,738
• Year to date:
  • Site-wide: 90,402
• Since beginning of last month:
  • Site-wide: 162,689

Prediction of LncRNA Encoded Small Peptides in Glioma and The Oligomer Channel Functional Analysis Using in Silico Approaches

• Downloaded 297 times
• Download rankings, all-time:
  • Site-wide: 160,868
  • In biophysics: 6,162
• Year to date:
  • Site-wide: 153,112
• Since beginning of last month:
  • Site-wide: 165,815

Stand-alone lipoylated H-protein of the glycine cleavage system enables glycine cleavage and the synthesis of glycine from one-carbon compounds in vitro

• Downloaded 284 times
• Download rankings, all-time:
  • Site-wide: 164,926
  • In biochemistry: 5,147
• Year to date:
  • Site-wide: 52,643
• Since beginning of last month:
  • Site-wide: 64,359

Epidemiological and Clinical Features, Treatment Status, and Economic Burden of Traumatic Spinal Cord Injury in China

• Downloaded 279 times
• Download rankings, all-time:
  • Site-wide: 166,422
  • In epidemiology: 6,757
• Year to date:
  • Site-wide: 78,834
• Since beginning of last month:
  • Site-wide: 61,964

Integrative analysis with expanded DNA methylation data reveals common key regulators and pathways in cancers

• Downloaded 267 times
• Download rankings, all-time:
  • Site-wide: 169,992
  • In bioinformatics: 13,053
• Year to date:
  • Site-wide: 112,226
• Since beginning of last month:
  • Site-wide: 199,736

T-cell Repertoire Characteristics of Asymptomatic and Re-detectable Positive COVID-19 Patients

• Downloaded 252 times
• Download rankings, all-time:
  • Site-wide: 174,161
  • In immunology: 5,511
• Year to date:
  • Site-wide: 147,203
• Since beginning of last month:
  • Site-wide: 156,328

The influence of insulin therapy on measurements of optical coherence tomography parameters in diabetic patients without retinopathy

• Downloaded 251 times
• Download rankings, all-time:
  • Site-wide: 174,324
  • In physiology: 1,951
• Year to date:
  • Site-wide: 85,903
• Since beginning of last month:
  • Site-wide: 215,100

Brassinosteroids Promote Parenchyma Cell and Secondary Xylem Development in Sugar Beet (Beta vulgaris L.) Root

• Downloaded 245 times
• Download rankings, all-time:
  • Site-wide: 175,945
  • In plant biology: 4,913
• Year to date:
  • Site-wide: 81,784
• Since beginning of last month:
  • Site-wide: 212,282

Limbal Niche Cells in Three-Dimensional Matrigel Induced Dedifferentiation of Mature Corneal Epithelial Cells toward a Progenitor State

• Downloaded 244 times
• Download rankings, all-time:
  • Site-wide: 176,264
  • In bioengineering: 3,768
• Year to date:
  • Site-wide: 152,499
• Since beginning of last month:
  • Site-wide: 122,368

Identification of biomarkers and candidate inhibitors for multiple myeloma

• Downloaded 231 times
• Download rankings, all-time:
  • Site-wide: 179,811
  • In bioinformatics: 13,485
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 156,410

Functional Characterization of a Lassa Virus Fusion Inhibitors Adaptive Mutant

• Downloaded 220 times
• Download rankings, all-time:
  • Site-wide: 182,588
  • In microbiology: 13,534
• Year to date:
  • Site-wide: 126,582
• Since beginning of last month:
  • Site-wide: 158,181

Screening and Identification of Lassa Virus Endonuclease-targeting Inhibitors from a Fragment-based Drug Development Library

• Downloaded 217 times
• Download rankings, all-time:
  • Site-wide: 183,341
  • In microbiology: 13,604
• Year to date:
  • Site-wide: 176,371
• Since beginning of last month:
  • Site-wide: 137,960

IFT-A deficiency in juvenile mice impairs biliary development and exacerbates ADPKD liver disease

• Downloaded 216 times
• Download rankings, all-time:
  • Site-wide: 183,734
  • In genetics: 6,605
• Year to date:
  • Site-wide: 81,631
• Since beginning of last month:
  • Site-wide: 123,989

Identification of residues in Lassa virus glycoprotein 1 involved in receptor switch

• Downloaded 215 times
• Download rankings, all-time:
  • Site-wide: 183,883
  • In microbiology: 13,696
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 156,281

CD98 is critical for a conserved inflammatory response to diverse injury stimuli relevant to IPF exacerbations and COVID pneumonitis

• Downloaded 211 times
• Download rankings, all-time:
  • Site-wide: 184,809
  • In cell biology: 8,833
• Year to date:
  • Site-wide: 15,171
• Since beginning of last month:
  • Site-wide: 28,593

Association of Visual Impairment with Risk for Future Parkinson's Disease

• Downloaded 210 times
• Download rankings, all-time:
  • Site-wide: 185,035
  • In epidemiology: 7,345
• Year to date:
  • Site-wide: 161,023
• Since beginning of last month:
  • Site-wide: 172,056

Genome-wide identification of long non-coding RNAs in the gravid ectoparasite Varroa destructor

• Downloaded 200 times
• Download rankings, all-time:
  • Site-wide: 187,474
  • In genomics: 8,920
• Year to date:
  • Site-wide: 152,071
• Since beginning of last month:
  • Site-wide: 166,557

Enhanced clinical assessment of hematologic malignancies through routine paired tumor:normal sequencing

• Downloaded 194 times
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  • Site-wide: 188,946
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Screening of Botanical Drugs Against Lassa Virus Entry

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Young APPKI NL-G-F/NL-G-F mice display high-fat diet-induced metabolic disturbances and specific disorders associated with brain energy homeostasis.

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Effects of N-linked glycan of Lassa Virus Envelope Glycoprotein on the Immune Response

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Association of Age-Related Macular Degeneration With Mortality: A Propensity Score-Matched Analysis

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Screening and Identification of Lujo Virus Entry Inhibitors from an FDA-Approved Drugs Library

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Inferring CTCF insulators and anchored loops across human tissues and cell types

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Neural network facilitated ab initio derivation of linear formula: A case study on formulating the relationship between DNA motifs and gene expression

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SARS-CoV-2 containment was achievable during the early stage of the pandemic: a retrospective modelling study of the Xinfadi outbreak in Beijing

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Association of cortical arousals with sleep-disordered breathing events

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Mechanism through which retrocyclin targets flavivirus multiplication

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Diurnal rhythm of temporal reproduction in the visual field.

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A tracheal aspirate-derived airway basal cell model reveals a pro-inflammatory epithelial defect in congenital diaphragmatic hernia

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Interpretable Prediction of mRNA Abundance from Promoter Sequence using Contextual Regression Models

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