Author: Rogier W. Sanders

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Preprints

Comparative assessment of multiple COVID-19 serological technologies supports continued evaluation of point-of-care lateral flow assays in hospital and community healthcare settings

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  • Site-wide: 1,481
  • In infectious diseases: 352
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 1,529

Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability

• Downloaded 3,707 times
• Download rankings, all-time:
  • Site-wide: 2,604
  • In microbiology: 176
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 86,911

Afucosylated immunoglobulin G responses are a hallmark of enveloped virus infections and show an exacerbated phenotype in COVID-19

• Downloaded 2,531 times
• Download rankings, all-time:
  • Site-wide: 4,511
  • In immunology: 115
• Year to date:
  • Site-wide: 1,081
• Since beginning of last month:
  • Site-wide: 994

SARS-CoV-2 Infection and Transmission Depends on Heparan Sulfates and Is Blocked by Low Molecular Weight Heparins

• Downloaded 1,765 times
• Download rankings, all-time:
  • Site-wide: 7,685
  • In immunology: 204
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 21,913

Cross-neutralization of a SARS-CoV-2 antibody to a functionally conserved site is mediated by avidity

• Downloaded 809 times
• Download rankings, all-time:
  • Site-wide: 24,597
  • In microbiology: 1,388
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 37,362

An alternative binding mode of IGHV3-53 antibodies to the SARS-CoV-2 receptor binding domain

• Downloaded 677 times
• Download rankings, all-time:
  • Site-wide: 31,498
  • In microbiology: 1,835
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 81,841

Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens

• Downloaded 654 times
• Download rankings, all-time:
  • Site-wide: 32,999
  • In immunology: 878
• Year to date:
  • Site-wide: 33,689
• Since beginning of last month:
  • Site-wide: 32,604

Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates

• Downloaded 559 times
• Download rankings, all-time:
  • Site-wide: 40,199
  • In immunology: 1,067
• Year to date:
  • Site-wide: 32,155
• Since beginning of last month:
  • Site-wide: 28,246

Vaccine-induced protection from homologous Tier 2 simian-human immunodeficiency virus challenge in nonhuman primates

• Downloaded 536 times
• Download rankings, all-time:
  • Site-wide: 42,356
  • In immunology: 1,125
• Year to date:
  • Site-wide: 22,459
• Since beginning of last month:
  • Site-wide: 56,477

Two-component spike nanoparticle vaccine protects macaques from SARS-CoV-2 infection

• Downloaded 509 times
• Download rankings, all-time:
  • Site-wide: 45,130
  • In immunology: 1,205
• Year to date:
  • Site-wide: 2,654
• Since beginning of last month:
  • Site-wide: 5,654

Similarities and differences between native HIV-1 envelope glycoprotein trimers and stabilized soluble trimer mimetics

• Downloaded 438 times
• Download rankings, all-time:
  • Site-wide: 53,346
  • In immunology: 1,424
• Year to date:
  • Site-wide: 56,918
• Since beginning of last month:
  • Site-wide: 111,545

Neutralizing antibody responses to an HIV envelope glycan hole are not easily broadened

• Downloaded 316 times
• Download rankings, all-time:
  • Site-wide: 72,305
  • In immunology: 1,941
• Year to date:
  • Site-wide: 58,148
• Since beginning of last month:
  • Site-wide: 63,944

HIV Envelope Trimer-Elicited Autologous Neutralizing Antibodies Bind a Region Overlapping the N332 Glycan Supersite

• Downloaded 287 times
• Download rankings, all-time:
  • Site-wide: 77,660
  • In immunology: 2,086
• Year to date:
  • Site-wide: 61,318
• Since beginning of last month:
  • Site-wide: 69,122

Networks of HIV-1 envelope glycans maintain antibody epitopes in the face of glycan additions and deletions

• Downloaded 257 times
• Download rankings, all-time:
  • Site-wide: 83,753
  • In immunology: 2,281
• Year to date:
  • Site-wide: 68,877
• Since beginning of last month:
  • Site-wide: 70,842

Enhancing glycan occupancy of soluble HIV-1 envelope trimers to mimic the native viral spike

• Downloaded 192 times
• Download rankings, all-time:
  • Site-wide: 97,443
  • In biochemistry: 2,899
• Year to date:
  • Site-wide: 26,471
• Since beginning of last month:
  • Site-wide: 34,306

Intramolecular quality control: HIV-1 Envelope gp160 signal-peptide cleavage as a functional folding checkpoint

• Downloaded 103 times
• Download rankings, all-time:
  • Site-wide: 113,913
  • In biochemistry: 3,470
• Year to date:
  • Site-wide: 7,784
• Since beginning of last month:
  • Site-wide: 45,483

Immunofocusing and enhancing autologous Tier-2 HIV-1 neutralization by displaying Env trimers on two-component protein nanoparticles

• Downloaded 103 times
• Download rankings, all-time:
  • Site-wide: 113,805
  • In microbiology: 8,593
• Year to date:
  • Site-wide: 19,452
• Since beginning of last month:
  • Site-wide: 4,806