Rxivist combines preprints from bioRxiv with data from Twitter to help you find the papers being discussed in your field. Currently indexing 72,923 bioRxiv papers from 317,485 authors.

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Preprints

An open resource of structural variation for medical and population genetics

• Downloaded 8,772 times
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  • In genomics: 51 out of 4,843
• Year to date:
  • Site-wide: 225 out of 72,924
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  • Site-wide: 225 out of 72,924

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

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  • In genomics: 146 out of 4,843
• Year to date:
  • Site-wide: 598 out of 72,924
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  • Site-wide: 598 out of 72,924

Fine-mapping of an expanded set of type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

• Downloaded 3,053 times
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  • In genomics: 285 out of 4,843
• Year to date:
  • Site-wide: 15,079 out of 72,924
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Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

• Downloaded 2,987 times
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  • In genetics: 119 out of 4,008
• Year to date:
  • Site-wide: 18,513 out of 72,924
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  • Site-wide: 18,513 out of 72,924

Genetic analysis of over one million people identifies 535 novel loci for blood pressure.

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  • In genetics: 134 out of 4,008
• Year to date:
  • Site-wide: 12,335 out of 72,924
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  • Site-wide: 12,335 out of 72,924

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

• Downloaded 1,720 times
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  • In genetics: 288 out of 4,008
• Year to date:
  • Site-wide: 20,112 out of 72,924
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  • Site-wide: 20,112 out of 72,924

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

• Downloaded 1,273 times
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  • In genetics: 452 out of 4,008
• Year to date:
  • Site-wide: 12,424 out of 72,924
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  • Site-wide: 12,424 out of 72,924

Genome-wide association study provides new insights into the genetic architecture and pathogenesis of heart failure

• Downloaded 1,236 times
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  • In genetics: 472 out of 4,008
• Year to date:
  • Site-wide: 3,844 out of 72,924
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  • Site-wide: 3,844 out of 72,924

Inherited Causes of Clonal Hematopoiesis of Indeterminate Potential in TOPMed Whole Genomes

• Downloaded 1,174 times
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  • In genomics: 1,071 out of 4,843
• Year to date:
  • Site-wide: 1,632 out of 72,924
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  • Site-wide: 1,632 out of 72,924

Atrial Fibrillation Genetic Risk Differentiates Cardioembolic Stroke from other Stroke Subtypes

• Downloaded 656 times
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  • Site-wide: 16,322 out of 72,924
  • In genetics: 1,108 out of 4,008
• Year to date:
  • Site-wide: 26,096 out of 72,924
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  • Site-wide: 26,096 out of 72,924

Novel blood pressure locus and gene discovery using GWAS and expression datasets from blood and the kidney

• Downloaded 641 times
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  • In genomics: 2,103 out of 4,843
• Year to date:
  • Site-wide: 25,371 out of 72,924
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  • Site-wide: 25,371 out of 72,924

Trans-ethnic genome-wide association study provides insight into effector genes and molecular mechanisms for kidney function and highlights a causal effect on kidney-specific disease aetiologies

• Downloaded 629 times
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  • Site-wide: 17,314 out of 72,924
  • In genetics: 1,175 out of 4,008
• Year to date:
  • Site-wide: 40,269 out of 72,924
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  • Site-wide: 40,269 out of 72,924

Loss-of-function genomic variants with impact on liver-related blood traits highlight potential therapeutic targets for cardiovascular disease

• Downloaded 526 times
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  • In genomics: 2,489 out of 4,843
• Year to date:
  • Site-wide: 11,972 out of 72,924
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  • Site-wide: 11,972 out of 72,924

Multiethnic Meta-analysis Identifies New Loci for Pulmonary Function

• Downloaded 518 times
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  • In genetics: 1,499 out of 4,008
• Year to date:
  • Site-wide: 67,144 out of 72,924
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  • Site-wide: 67,144 out of 72,924

Novel genetic determinants of telomere length from a multi-ethnic analysis of 75,000 whole genome sequences in TOPMed

• Downloaded 500 times
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  • Site-wide: 23,637 out of 72,924
  • In genetics: 1,548 out of 4,008
• Year to date:
  • Site-wide: 9,321 out of 72,924
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  • Site-wide: 9,321 out of 72,924

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

• Downloaded 490 times
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  • Site-wide: 24,211 out of 72,924
  • In genomics: 2,638 out of 4,843
• Year to date:
  • Site-wide: 11,248 out of 72,924
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  • Site-wide: 11,248 out of 72,924

Mitochondrial DNA Copy Number (mtDNA-CN) Can Influence Mortality and Cardiovascular Disease via Methylation of Nuclear DNA CpGs

• Downloaded 461 times
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  • In genomics: 2,769 out of 4,843
• Year to date:
  • Site-wide: 11,852 out of 72,924
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  • Site-wide: 11,852 out of 72,924

Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation

• Downloaded 436 times
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  • Site-wide: 27,767 out of 72,924
  • In genetics: 1,785 out of 4,008
• Year to date:
  • Site-wide: 6,314 out of 72,924
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  • Site-wide: 6,314 out of 72,924

Multi-ancestry analysis of gene-sleep interactions in 126,926 individuals identifies multiple novel blood lipid loci that contribute to our understanding of sleep-associated adverse blood lipid profile

• Downloaded 416 times
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  • Site-wide: 29,371 out of 72,924
  • In genomics: 2,994 out of 4,843
• Year to date:
  • Site-wide: 42,552 out of 72,924
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  • Site-wide: 42,552 out of 72,924

Meta-analysis of exome array data identifies six novel genetic loci for lung function

• Downloaded 405 times
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  • Site-wide: 30,264 out of 72,924
  • In genetics: 1,910 out of 4,008
• Year to date:
  • Site-wide: 57,490 out of 72,924
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  • Site-wide: 57,490 out of 72,924

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 210 loci underlying cardiac conduction

• Downloaded 389 times
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  • Site-wide: 31,548 out of 72,924
  • In genetics: 1,982 out of 4,008
• Year to date:
  • Site-wide: 12,655 out of 72,924
• Since beginning of last month:
  • Site-wide: 12,655 out of 72,924

Multi-ethnic genome-wide association study of decomposed cardioelectric phenotypes illustrates strategies to identify and characterize evidence of shared genetic effects for complex traits

• Downloaded 224 times
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  • Site-wide: 50,414 out of 72,924
  • In epidemiology: 938 out of 1,556
• Year to date:
  • Site-wide: 47,558 out of 72,924
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  • Site-wide: 47,558 out of 72,924

GWAS of QRS Duration Identifies New Loci Specific to Hispanic/Latino Populations

• Downloaded 197 times
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  • Site-wide: 54,457 out of 72,924
  • In genetics: 3,180 out of 4,008
• Year to date:
  • Site-wide: 53,672 out of 72,924
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  • Site-wide: 53,672 out of 72,924

Evaluation of the causal effect of fibrinogen on incident coronary heart disease via Mendelian randomization

• Downloaded 193 times
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  • Site-wide: 54,983 out of 72,924
  • In genetics: 3,205 out of 4,008
• Year to date:
  • Site-wide: 55,525 out of 72,924
• Since beginning of last month:
  • Site-wide: 55,525 out of 72,924