Author: Kent D. Taylor

Downloads per author, site-wide

Preprints

An open resource of structural variation for medical and population genetics

• Downloaded 9,267 times
• Download rankings, all-time:
  • Site-wide: 195 out of 77,629
  • In genomics: 49 out of 5,088
• Year to date:
  • Site-wide: 322 out of 77,629
• Since beginning of last month:
  • Site-wide: 582 out of 77,629

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

• Downloaded 4,846 times
• Download rankings, all-time:
  • Site-wide: 596 out of 77,629
  • In genomics: 137 out of 5,088
• Year to date:
  • Site-wide: 851 out of 77,629
• Since beginning of last month:
  • Site-wide: 1,244 out of 77,629

Fine-mapping of an expanded set of type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

• Downloaded 3,098 times
• Download rankings, all-time:
  • Site-wide: 1,368 out of 77,629
  • In genomics: 300 out of 5,088
• Year to date:
  • Site-wide: 18,203 out of 77,629
• Since beginning of last month:
  • Site-wide: 11,492 out of 77,629

Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

• Downloaded 3,020 times
• Download rankings, all-time:
  • Site-wide: 1,420 out of 77,629
  • In genetics: 122 out of 4,189
• Year to date:
  • Site-wide: 24,338 out of 77,629
• Since beginning of last month:
  • Site-wide: 19,674 out of 77,629

Genetic analysis of over one million people identifies 535 novel loci for blood pressure.

• Downloaded 2,855 times
• Download rankings, all-time:
  • Site-wide: 1,577 out of 77,629
  • In genetics: 138 out of 4,189
• Year to date:
  • Site-wide: 21,040 out of 77,629
• Since beginning of last month:
  • Site-wide: 20,830 out of 77,629

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

• Downloaded 1,741 times
• Download rankings, all-time:
  • Site-wide: 3,727 out of 77,629
  • In genetics: 296 out of 4,189
• Year to date:
  • Site-wide: 32,339 out of 77,629
• Since beginning of last month:
  • Site-wide: 26,925 out of 77,629

Inherited Causes of Clonal Hematopoiesis of Indeterminate Potential in TOPMed Whole Genomes

• Downloaded 1,427 times
• Download rankings, all-time:
  • Site-wide: 5,212 out of 77,629
  • In genomics: 893 out of 5,088
• Year to date:
  • Site-wide: 1,384 out of 77,629
• Since beginning of last month:
  • Site-wide: 1,309 out of 77,629

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

• Downloaded 1,318 times
• Download rankings, all-time:
  • Site-wide: 5,953 out of 77,629
  • In genetics: 453 out of 4,189
• Year to date:
  • Site-wide: 16,756 out of 77,629
• Since beginning of last month:
  • Site-wide: 12,232 out of 77,629

Genome-wide association study provides new insights into the genetic architecture and pathogenesis of heart failure

• Downloaded 1,277 times
• Download rankings, all-time:
  • Site-wide: 6,262 out of 77,629
  • In genetics: 476 out of 4,189
• Year to date:
  • Site-wide: 8,426 out of 77,629
• Since beginning of last month:
  • Site-wide: 30,207 out of 77,629

Atrial Fibrillation Genetic Risk Differentiates Cardioembolic Stroke from other Stroke Subtypes

• Downloaded 676 times
• Download rankings, all-time:
  • Site-wide: 17,184 out of 77,629
  • In genetics: 1,140 out of 4,189
• Year to date:
  • Site-wide: 38,016 out of 77,629
• Since beginning of last month:
  • Site-wide: 29,177 out of 77,629

Novel blood pressure locus and gene discovery using GWAS and expression datasets from blood and the kidney

• Downloaded 664 times
• Download rankings, all-time:
  • Site-wide: 17,648 out of 77,629
  • In genomics: 2,153 out of 5,088
• Year to date:
  • Site-wide: 34,269 out of 77,629
• Since beginning of last month:
  • Site-wide: 35,322 out of 77,629

Novel genetic determinants of telomere length from a multi-ethnic analysis of 75,000 whole genome sequences in TOPMed

• Downloaded 645 times
• Download rankings, all-time:
  • Site-wide: 18,403 out of 77,629
  • In genetics: 1,217 out of 4,189
• Year to date:
  • Site-wide: 4,979 out of 77,629
• Since beginning of last month:
  • Site-wide: 5,584 out of 77,629

Trans-ethnic genome-wide association study provides insight into effector genes and molecular mechanisms for kidney function and highlights a causal effect on kidney-specific disease aetiologies

• Downloaded 644 times
• Download rankings, all-time:
  • Site-wide: 18,465 out of 77,629
  • In genetics: 1,221 out of 4,189
• Year to date:
  • Site-wide: 53,101 out of 77,629
• Since beginning of last month:
  • Site-wide: 47,684 out of 77,629

Loss-of-function genomic variants with impact on liver-related blood traits highlight potential therapeutic targets for cardiovascular disease

• Downloaded 562 times
• Download rankings, all-time:
  • Site-wide: 22,285 out of 77,629
  • In genomics: 2,495 out of 5,088
• Year to date:
  • Site-wide: 18,850 out of 77,629
• Since beginning of last month:
  • Site-wide: 29,508 out of 77,629

Mitochondrial DNA Copy Number (mtDNA-CN) Can Influence Mortality and Cardiovascular Disease via Methylation of Nuclear DNA CpGs

• Downloaded 537 times
• Download rankings, all-time:
  • Site-wide: 23,696 out of 77,629
  • In genomics: 2,604 out of 5,088
• Year to date:
  • Site-wide: 10,906 out of 77,629
• Since beginning of last month:
  • Site-wide: 5,305 out of 77,629

Multiethnic Meta-analysis Identifies New Loci for Pulmonary Function

• Downloaded 531 times
• Download rankings, all-time:
  • Site-wide: 24,013 out of 77,629
  • In genetics: 1,551 out of 4,189
• Year to date:
  • Site-wide: 67,282 out of 77,629
• Since beginning of last month:
  • Site-wide: 61,135 out of 77,629

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

• Downloaded 515 times
• Download rankings, all-time:
  • Site-wide: 24,972 out of 77,629
  • In genomics: 2,686 out of 5,088
• Year to date:
  • Site-wide: 21,810 out of 77,629
• Since beginning of last month:
  • Site-wide: 48,567 out of 77,629

Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation

• Downloaded 488 times
• Download rankings, all-time:
  • Site-wide: 26,662 out of 77,629
  • In genetics: 1,697 out of 4,189
• Year to date:
  • Site-wide: 10,495 out of 77,629
• Since beginning of last month:
  • Site-wide: 17,425 out of 77,629

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 210 loci underlying cardiac conduction

• Downloaded 432 times
• Download rankings, all-time:
  • Site-wide: 30,794 out of 77,629
  • In genetics: 1,905 out of 4,189
• Year to date:
  • Site-wide: 17,371 out of 77,629
• Since beginning of last month:
  • Site-wide: 19,317 out of 77,629

Multi-ancestry analysis of gene-sleep interactions in 126,926 individuals identifies multiple novel blood lipid loci that contribute to our understanding of sleep-associated adverse blood lipid profile

• Downloaded 430 times
• Download rankings, all-time:
  • Site-wide: 31,025 out of 77,629
  • In genomics: 3,097 out of 5,088
• Year to date:
  • Site-wide: 54,425 out of 77,629
• Since beginning of last month:
  • Site-wide: 40,768 out of 77,629

Meta-analysis of exome array data identifies six novel genetic loci for lung function

• Downloaded 418 times
• Download rankings, all-time:
  • Site-wide: 32,016 out of 77,629
  • In genetics: 1,964 out of 4,189
• Year to date:
  • Site-wide: 62,246 out of 77,629
• Since beginning of last month:
  • Site-wide: 55,882 out of 77,629

Multi-ethnic genome-wide association study of decomposed cardioelectric phenotypes illustrates strategies to identify and characterize evidence of shared genetic effects for complex traits

• Downloaded 241 times
• Download rankings, all-time:
  • Site-wide: 52,503 out of 77,629
  • In epidemiology: 961 out of 1,556
• Year to date:
  • Site-wide: 52,268 out of 77,629
• Since beginning of last month:
  • Site-wide: 39,562 out of 77,629

Evaluation of the causal effect of fibrinogen on incident coronary heart disease via Mendelian randomization

• Downloaded 216 times
• Download rankings, all-time:
  • Site-wide: 56,298 out of 77,629
  • In genetics: 3,230 out of 4,189
• Year to date:
  • Site-wide: 47,214 out of 77,629
• Since beginning of last month:
  • Site-wide: 36,615 out of 77,629

GWAS of QRS Duration Identifies New Loci Specific to Hispanic/Latino Populations

• Downloaded 207 times
• Download rankings, all-time:
  • Site-wide: 57,611 out of 77,629
  • In genetics: 3,293 out of 4,189
• Year to date:
  • Site-wide: 66,278 out of 77,629
• Since beginning of last month:
  • Site-wide: 52,558 out of 77,629

Genetic loci associated with prevalent and incident myocardial infarction and coronary heart disease in the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium

• Downloaded 152 times
• Download rankings, all-time:
  • Site-wide: 66,441 out of 77,629
  • In genetics: 3,706 out of 4,189
• Year to date:
  • Site-wide: 7,407 out of 77,629
• Since beginning of last month:
  • Site-wide: 6,981 out of 77,629