Author: Steven A. Lubitz

Downloads per author, site-wide

Preprints

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

• Downloaded 8,465 times
• Download rankings, all-time:
  • Site-wide: 1,202
  • In genomics: 97
• Year to date:
  • Site-wide: 3,936
• Since beginning of last month:
  • Site-wide: 57,857

Inherited Causes of Clonal Hematopoiesis of Indeterminate Potential in TOPMed Whole Genomes

• Downloaded 3,094 times
• Download rankings, all-time:
  • Site-wide: 4,719
  • In genomics: 488
• Year to date:
  • Site-wide: 10,255
• Since beginning of last month:
  • Site-wide: 88,996

Rare Genetic Variation Underlying Human Diseases and Traits: Results from 200,000 Individuals in the UK Biobank

• Downloaded 2,760 times
• Download rankings, all-time:
  • Site-wide: 5,525
  • In genetics: 231
• Year to date:
  • Site-wide: 3,884
• Since beginning of last month:
  • Site-wide: 66,562

Deep learning enables genetic analysis of the human thoracic aorta

• Downloaded 1,737 times
• Download rankings, all-time:
  • Site-wide: 10,960
  • In genomics: 1,125
• Year to date:
  • Site-wide: 7,753
• Since beginning of last month:
  • Site-wide: 60,575

Genome-wide association study provides new insights into the genetic architecture and pathogenesis of heart failure

• Downloaded 1,496 times
• Download rankings, all-time:
  • Site-wide: 13,614
  • In genetics: 620
• Year to date:
  • Site-wide: 114,206
• Since beginning of last month:
  • Site-wide: 100,383

Analysis of cardiac magnetic resonance imaging traits in 29,000 individuals reveals shared genetic basis with dilated cardiomyopathy

• Downloaded 893 times
• Download rankings, all-time:
  • Site-wide: 29,278
  • In genomics: 2,593
• Year to date:
  • Site-wide: 56,406
• Since beginning of last month:
  • Site-wide: 19,799

Prevalence and clinical importance of titin truncating variants in adults without known congestive heart failure

• Downloaded 877 times
• Download rankings, all-time:
  • Site-wide: 29,980
  • In cardiovascular medicine: 46
• Year to date:
  • Site-wide: 68,567
• Since beginning of last month:
  • Site-wide: 67,951

Atrial Fibrillation Genetic Risk Differentiates Cardioembolic Stroke from other Stroke Subtypes

• Downloaded 861 times
• Download rankings, all-time:
  • Site-wide: 30,806
  • In genetics: 1,416
• Year to date:
  • Site-wide: 86,936
• Since beginning of last month:
  • Site-wide: 87,471

Rare coding variants in 35 genes associate with circulating lipid levels: a multi-ancestry analysis of 170,000 exomes

• Downloaded 848 times
• Download rankings, all-time:
  • Site-wide: 31,461
  • In genetics: 1,447
• Year to date:
  • Site-wide: 7,471
• Since beginning of last month:
  • Site-wide: 4,474

Loss-of-function genomic variants with impact on liver-related blood traits highlight potential therapeutic targets for cardiovascular disease

• Downloaded 799 times
• Download rankings, all-time:
  • Site-wide: 34,147
  • In genomics: 2,910
• Year to date:
  • Site-wide: 79,007
• Since beginning of last month:
  • Site-wide: 38,986

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

• Downloaded 692 times
• Download rankings, all-time:
  • Site-wide: 41,605
  • In genomics: 3,358
• Year to date:
  • Site-wide: 107,152
• Since beginning of last month:
  • Site-wide: 57,718

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 210 loci underlying cardiac conduction

• Downloaded 651 times
• Download rankings, all-time:
  • Site-wide: 45,078
  • In genetics: 2,017
• Year to date:
  • Site-wide: 93,603
• Since beginning of last month:
  • Site-wide: 35,853

Genetic Analysis of Right Heart Structure and Function in 40,000 People

• Downloaded 622 times
• Download rankings, all-time:
  • Site-wide: 47,757
  • In genetics: 2,131
• Year to date:
  • Site-wide: 6,676
• Since beginning of last month:
  • Site-wide: 81,567

Genome-wide association meta-analysis of PR interval identifies 47 novel loci associated with atrial and atrioventricular electrical activity

• Downloaded 615 times
• Download rankings, all-time:
  • Site-wide: 48,478
  • In genetics: 2,164
• Year to date:
  • Site-wide: 93,851
• Since beginning of last month:
  • Site-wide: 51,815

Rare Non-coding Variation Identified by Large Scale Whole Genome Sequencing Reveals Unexplained Heritability of Type 2 Diabetes: Trans-Omics for Precision Medicine (TOPMed) Program

• Downloaded 460 times
• Download rankings, all-time:
  • Site-wide: 68,185
  • In genetic and genomic medicine: 281
• Year to date:
  • Site-wide: 24,960
• Since beginning of last month:
  • Site-wide: 41,991

Robust, flexible, and scalable tests for Hardy-Weinberg Equilibrium across diverse ancestries

• Downloaded 369 times
• Download rankings, all-time:
  • Site-wide: 84,481
  • In bioinformatics: 7,586
• Year to date:
  • Site-wide: 73,204
• Since beginning of last month:
  • Site-wide: 125,111

Monogenic and Polygenic Contributions to QTc Prolongation in the Population

• Downloaded 244 times
• Download rankings, all-time:
  • Site-wide: 112,925
  • In genetic and genomic medicine: 580
• Year to date:
  • Site-wide: 25,463
• Since beginning of last month:
  • Site-wide: 18,762

Deep Learning to Estimate Cardiac Magnetic Resonance-Derived Left Ventricular Mass

• Downloaded 232 times
• Download rankings, all-time:
  • Site-wide: 116,041
  • In cardiovascular medicine: 273
• Year to date:
  • Site-wide: 45,864
• Since beginning of last month:
  • Site-wide: 54,981

Massachusetts General Hospital Covid-19 Registry reveals two distinct populations of hospitalized patients by race and ethnicity

• Downloaded 232 times
• Download rankings, all-time:
  • Site-wide: 116,023
  • In infectious diseases: 4,833
• Year to date:
  • Site-wide: 120,727
• Since beginning of last month:
  • Site-wide: 121,956

Cohort Design and Natural Language Processing to Reduce Bias in Electronic Health Records Research: The Community Care Cohort Project

• Downloaded 171 times
• Download rankings, all-time:
  • Site-wide: 130,973
  • In epidemiology: 5,480
• Year to date:
  • Site-wide: 39,468
• Since beginning of last month:
  • Site-wide: 91,697

Screening for Atrial Fibrillation in Older Adults at Primary Care Visits: the VITAL-AF Randomized Controlled Trial

• Downloaded 134 times
• Download rankings, all-time:
  • Site-wide: 139,445
  • In cardiovascular medicine: 430
• Year to date:
  • Site-wide: 51,772
• Since beginning of last month:
  • Site-wide: 2,182

Endophenotype Effect Sizes Provide Evidence Supporting Variant Pathogenicity in Monogenic Disease Susceptibility Genes

• Downloaded 57 times
• Download rankings, all-time:
  • Site-wide: 151,627
  • In genetic and genomic medicine: 907
• Year to date:
  • Site-wide: 105,701
• Since beginning of last month:
  • Site-wide: 7,010

Accelerometer-Derived and Genetically Inferred Physical Activity and Human Disease

• Downloaded 5 times
• Download rankings, all-time:
  • Site-wide: 154,883
  • In epidemiology: 6,369
• Year to date:
  • Site-wide: 154,796
• Since beginning of last month:
  • Site-wide: 76,453

Deep Learning of Left Atrial Structure and Function Provides Link to Atrial Fibrillation Risk

• Downloaded 3 times
• Download rankings, all-time:
  • Site-wide: 155,054
  • In cardiovascular medicine: 499
• Year to date:
  • Site-wide: 155,028
• Since beginning of last month:
  • Site-wide: 80,750