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Author: Patrick E MacDonald

  • ORCiD: http://orcid.org/0000-0002-5439-6288
  • Most recently observed institution: Alberta Diabetes Institute and Department of Pharmacology, University of Alberta, Edmonton, Canada

Rankings

  • All-time downloads: 12,368 (rank: 20,408 (tie) )
  • Categories:
    • cell biology: 2,189 (rank: 3,564 (tie) )
    • genetics: 1,772 (rank: 11,718 (tie) )
    • genomics: 5,163 (rank: 5,318 )
    • physiology: 3,244 (rank: 65 )

Downloads per author, site-wide

Preprints

Pancreas patch-seq links physiologic dysfunction in diabetes to single-cell transcriptomic phenotypes

genomics more details view paper
  • Downloaded 2,756 times
  • Download rankings, all-time:
    • Site-wide: 6,195
    • In genomics: 622
  • Year to date:
    • Site-wide: 48,348
  • Since beginning of last month:
    • Site-wide: 133,981

Influence of genetic variants on gene expression in human pancreatic islets – implications for type 2 diabetes

genomics more details view paper
  • Downloaded 1,718 times
  • Download rankings, all-time:
    • Site-wide: 12,490
    • In genomics: 1,248
  • Year to date:
    • Site-wide: 52,704
  • Since beginning of last month:
    • Site-wide: 63,589

Aging of human endocrine pancreatic cell types is heterogeneous and sex-specific

physiology more details view paper
  • Downloaded 1,264 times
  • Download rankings, all-time:
    • Site-wide: 19,977
    • In physiology: 53
  • Year to date:
    • Site-wide: 28,308
  • Since beginning of last month:
    • Site-wide: 40,262

Beta-cell specific Insr deletion promotes insulin hypersecretion and improves glucose tolerance prior to global insulin resistance

physiology more details view paper
  • Downloaded 1,244 times
  • Download rankings, all-time:
    • Site-wide: 20,470
    • In physiology: 55
  • Year to date:
    • Site-wide: 7,719
  • Since beginning of last month:
    • Site-wide: 7,093

Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation

genetics more details view paper
  • Downloaded 1,079 times
  • Download rankings, all-time:
    • Site-wide: 25,438
    • In genetics: 1,118
  • Year to date:
    • Site-wide: 29,738
  • Since beginning of last month:
    • Site-wide: 60,741

Type 2 Diabetes Risk Alleles Reveal a Role for Peptidylglycine Alpha-amidating Monooxygenase in Beta Cell Function

genetics more details view paper
  • Downloaded 693 times
  • Download rankings, all-time:
    • Site-wide: 48,344
    • In genetics: 2,076
  • Year to date:
    • Site-wide: 115,225
  • Since beginning of last month:
    • Site-wide: 108,745

Combinatorial transcription factor profiles predict mature and functional human islet α and β cells

genomics more details view paper
  • Downloaded 689 times
  • Download rankings, all-time:
    • Site-wide: 48,679
    • In genomics: 3,726
  • Year to date:
    • Site-wide: 9,567
  • Since beginning of last month:
    • Site-wide: 18,722

A glucose-dependent spatial patterning of exocytosis in human β-cells is disrupted in type 2 diabetes

cell biology more details view paper
  • Downloaded 687 times
  • Download rankings, all-time:
    • Site-wide: 48,913
    • In cell biology: 2,057
  • Year to date:
    • Site-wide: 140,564
  • Since beginning of last month:
    • Site-wide: 145,241

Heterogenous impairment of α-cell function in type 2 diabetes is linked to cell maturation state

cell biology more details view paper
  • Downloaded 670 times
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    • Site-wide: 50,672
    • In cell biology: 2,142
  • Year to date:
    • Site-wide: 9,994
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    • Site-wide: 8,913

Vitamin D-binding protein is required for the maintenance of α-cell function and glucagon secretion

physiology more details view paper
  • Downloaded 464 times
  • Download rankings, all-time:
    • Site-wide: 79,198
    • In physiology: 587
  • Year to date:
    • Site-wide: 119,303
  • Since beginning of last month:
    • Site-wide: 84,299

NFIA regulates granule recruitment and exocytosis in the adult pancreas

cell biology more details view paper
  • Downloaded 428 times
  • Download rankings, all-time:
    • Site-wide: 86,162
    • In cell biology: 3,964
  • Year to date:
    • Site-wide: 113,150
  • Since beginning of last month:
    • Site-wide: 93,074

A new hypothesis for type 1 diabetes risk: The at-risk allele at rs3842753 associates with increased beta cell INS mRNA in a meta-analysis of single cell RNA sequencing data

cell biology more details view paper
  • Downloaded 404 times
  • Download rankings, all-time:
    • Site-wide: 91,248
    • In cell biology: 4,211
  • Year to date:
    • Site-wide: 42,190
  • Since beginning of last month:
    • Site-wide: 72,077

β-cell SENP1 facilitates responsiveness to incretins and limits oral glucose intolerance in high fat fed mice

physiology more details view paper
  • Downloaded 272 times
  • Download rankings, all-time:
    • Site-wide: 123,676
    • In physiology: 1,244
  • Year to date:
    • Site-wide: 69,903
  • Since beginning of last month:
    • Site-wide: 120,125

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