Author: Guillaume Lettre

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Preprints

Trans-ethnic and ancestry-specific blood-cell genetics in 746,667 individuals from 5 global populations

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  • Site-wide: 5,814
  • In genetics: 273
• Year to date:
  • Site-wide: 5,595
• Since beginning of last month:
  • Site-wide: 6,833

The Polygenic and Monogenic Basis of Blood Traits and Diseases

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  • Site-wide: 7,390
  • In genetic and genomic medicine: 25
• Year to date:
  • Site-wide: 22,065
• Since beginning of last month:
  • Site-wide: 18,456

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

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  • Site-wide: 9,851
  • In genetics: 469
• Year to date:
  • Site-wide: 63,035
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  • Site-wide: 42,507

Validation of genome-wide polygenic risk scores for coronary artery disease in French Canadians

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  • Site-wide: 16,286
  • In genetics: 801
• Year to date:
  • Site-wide: 64,869
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  • Site-wide: 69,728

Exome chip meta-analysis elucidates the genetic architecture of rare coding variants in smoking and drinking behavior

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  • Site-wide: 44,316
  • In genetics: 2,080
• Year to date:
  • Site-wide: 114,457
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  • Site-wide: 91,899

Whole genome sequencing association analysis of quantitative red blood cell phenotypes: the NHLBI TOPMed program

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  • Site-wide: 56,853
  • In hematology: 34
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  • Site-wide: 6,336
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  • Site-wide: 11,234

Pleiotropic effects for Parkin and LRRK2 in leprosy type-1 reactions and Parkinson's disease

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  • Site-wide: 73,094
  • In genetics: 3,346
• Year to date:
  • Site-wide: 112,941
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  • Site-wide: 115,249

Causal role of L-glutamine in sickle cell disease painful crises: a Mendelian randomization analysis

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  • Site-wide: 81,172
  • In genetics: 3,695
• Year to date:
  • Site-wide: 58,829
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  • Site-wide: 41,850

From GWAS Variant to Function: a Study of ~148,000 Variants for Blood Cell Traits.

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  • Site-wide: 104,998
  • In genetics: 4,633
• Year to date:
  • Site-wide: 9,975
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  • Site-wide: 5,372

find-tfbs: a tool to identify functional non-coding variants associated with complex human traits using open chromatin maps and phased whole-genome sequences

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  • Site-wide: 116,623
  • In genomics: 6,472
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  • Site-wide: 55,463
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  • Site-wide: 53,865

Transcriptomic profiling of atrial fibrillation canine models at disease onset

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  • Site-wide: 118,174
  • In genomics: 6,519
• Year to date:
  • Site-wide: 15,689
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  • Site-wide: 48,317

CRISPR perturbations at many coronary artery disease loci impair vascular endothelial cell functions

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  • Site-wide: 120,830
  • In genomics: 6,593
• Year to date:
  • Site-wide: 17,830
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  • Site-wide: 13,933