Author: Christopher P Nelson

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Preprints

Genomic risk prediction of coronary artery disease in nearly 500,000 adults: implications for early screening and primary prevention

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  • Site-wide: 3,119
  • In genetics: 103
• Year to date:
  • Site-wide: 58,891
• Since beginning of last month:
  • Site-wide: 56,062

Genetic analysis of over one million people identifies 535 novel loci for blood pressure.

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  • Site-wide: 4,477
  • In genetics: 171
• Year to date:
  • Site-wide: 37,030
• Since beginning of last month:
  • Site-wide: 103,740

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

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  • Site-wide: 10,834
  • In genetics: 478
• Year to date:
  • Site-wide: 54,153
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  • Site-wide: 19,806

Genome-wide association study provides new insights into the genetic architecture and pathogenesis of heart failure

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  • Site-wide: 13,614
  • In genetics: 620
• Year to date:
  • Site-wide: 114,206
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  • Site-wide: 100,383

Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants.

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  • Site-wide: 15,942
  • In genetic and genomic medicine: 69
• Year to date:
  • Site-wide: 2,231
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  • Site-wide: 714

Genetic predisposition to myeloproliferative neoplasms implicates hematopoietic stem cell biology

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  • Site-wide: 16,030
  • In genetics: 740
• Year to date:
  • Site-wide: 30,159
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  • Site-wide: 11,559

Genome-wide association and functional studies identify 46 novel loci for alcohol consumption and suggest common genetic mechanisms with neuropsychiatric disorders

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  • Site-wide: 17,750
  • In genetics: 821
• Year to date:
  • Site-wide: 65,187
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  • Site-wide: 23,267

Use of polygenic risk scores and other molecular markers to enhance cardiovascular risk prediction: Prospective cohort study and modelling analysis

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  • Site-wide: 20,759
  • In genomics: 1,989
• Year to date:
  • Site-wide: 65,412
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  • Site-wide: 29,672

Novel blood pressure locus and gene discovery using GWAS and expression datasets from blood and the kidney

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  • Site-wide: 35,625
  • In genomics: 2,997
• Year to date:
  • Site-wide: 117,854
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  • Site-wide: 104,863

Polygenic basis and biomedical consequences of telomere length variation

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  • Site-wide: 36,219
  • In epidemiology: 1,849
• Year to date:
  • Site-wide: 4,947
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  • Site-wide: 1,615

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 210 loci underlying cardiac conduction

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  • Site-wide: 45,078
  • In genetics: 2,017
• Year to date:
  • Site-wide: 93,603
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  • Site-wide: 35,853

Cis-epistasis at the LPA locus and risk of coronary artery disease

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  • Site-wide: 58,440
  • In genetics: 2,576
• Year to date:
  • Site-wide: 112,309
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  • Site-wide: None

A major population resource of 474,074 participants in UK Biobank to investigate determinants and biomedical consequences of leukocyte telomere length.

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  • Site-wide: 73,614
  • In genetic and genomic medicine: 312
• Year to date:
  • Site-wide: 11,603
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  • Site-wide: 8,456

Older biological age is associated with adverse COVID-19 outcomes: A cohort study in UK Biobank

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  • Site-wide: 93,980
  • In infectious diseases: 4,244
• Year to date:
  • Site-wide: 17,290
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  • Site-wide: 83,134

KCND3 is a novel susceptibility locus for early repolarization

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  • Site-wide: 107,318
  • In genetics: 4,543
• Year to date:
  • Site-wide: 146,727
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  • Site-wide: None

Association of leucocyte telomere length with frailty: a large-scale cross-sectional analysis in UK Biobank

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  • Site-wide: 137,221
  • In epidemiology: 5,692
• Year to date:
  • Site-wide: 47,849
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  • Site-wide: 132,132

Causal Associations of Self-Reported Walking Pace with Telomere Length in 405,981 middle-aged adults: a UK Biobank study

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  • Site-wide: 149,811
  • In sports medicine: 84
• Year to date:
  • Site-wide: 88,403
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  • Site-wide: 5,099