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Author: Darrell J Irvine

Rankings

  • All-time downloads: 19,273 (rank: 16,174 (tie) )
  • Categories:
    • bioengineering: 1,471 (rank: 3,953 )
    • cancer biology: 893 (rank: 16,908 (tie) )
    • cell biology: 1,649 (rank: 7,505 (tie) )
    • immunology: 12,495 (rank: 1,246 (tie) )
    • molecular biology: 1,418 (rank: 6,107 (tie) )

Downloads per author, site-wide

Preprints

CARPOOL: A library-based platform to rapidly identify next generation chimeric antigen receptors

immunology more details view paper
  • Downloaded 2,451 times
  • Download rankings, all-time:
    • Site-wide: 9,576
    • In immunology: 408
  • Year to date:
    • Site-wide: 3,391
  • Since beginning of last month:
    • Site-wide: 2,993

Long-lasting germinal center responses to a priming immunization with continuous proliferation and somatic mutation

immunology more details view paper
  • Downloaded 1,973 times
  • Download rankings, all-time:
    • Site-wide: 13,299
    • In immunology: 523
  • Year to date:
    • Site-wide: 3,238
  • Since beginning of last month:
    • Site-wide: 10,559

Cytoskeletal tension actively sustains the migratory T cell synaptic contact

cell biology more details view paper
  • Downloaded 1,683 times
  • Download rankings, all-time:
    • Site-wide: 16,953
    • In cell biology: 475
  • Year to date:
    • Site-wide: 109,550
  • Since beginning of last month:
    • Site-wide: 50,121

Engineered SARS-CoV-2 receptor binding domain improves immunogenicity in mice and elicits protective immunity in hamsters

molecular biology more details view paper
  • Downloaded 1,467 times
  • Download rankings, all-time:
    • Site-wide: 21,097
    • In molecular biology: 542
  • Year to date:
    • Site-wide: 31,700
  • Since beginning of last month:
    • Site-wide: 88,946

Spatially regulated protease activity in lymph nodes renders B cell follicles a sanctuary for retention of intact antigens

immunology more details view paper
  • Downloaded 1,409 times
  • Download rankings, all-time:
    • Site-wide: 22,482
    • In immunology: 861
  • Year to date:
    • Site-wide: 7,441
  • Since beginning of last month:
    • Site-wide: 14,198

Role of nanoscale antigen organization on B-cell activation probed using DNA origami

immunology more details view paper
  • Downloaded 1,357 times
  • Download rankings, all-time:
    • Site-wide: 23,862
    • In immunology: 847
  • Year to date:
    • Site-wide: 146,374
  • Since beginning of last month:
    • Site-wide: 41,345

Slow delivery immunization enhances HIV neutralizing antibody and germinal center responses via modulation of immunodominance

immunology more details view paper
  • Downloaded 1,324 times
  • Download rankings, all-time:
    • Site-wide: 24,834
    • In immunology: 874
  • Year to date:
    • Site-wide: 141,900
  • Since beginning of last month:
    • Site-wide: 45,369

The Injury Response to DNA Damage Promotes Anti-Tumor Immunity

cancer biology more details view paper
  • Downloaded 926 times
  • Download rankings, all-time:
    • Site-wide: 43,294
    • In cancer biology: 1,185
  • Year to date:
    • Site-wide: 55,440
  • Since beginning of last month:
    • Site-wide: 54,541

Controlling wireframe DNA origami nuclease degradation with minor groove binders

bioengineering more details view paper
  • Downloaded 780 times
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    • Site-wide: 55,985
    • In bioengineering: 1,113
  • Year to date:
    • Site-wide: 67,513
  • Since beginning of last month:
    • Site-wide: 21,112

Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques

immunology more details view paper
  • Downloaded 759 times
  • Download rankings, all-time:
    • Site-wide: 58,314
    • In immunology: 1,847
  • Year to date:
    • Site-wide: 43,599
  • Since beginning of last month:
    • Site-wide: None

Targeting HIV Env immunogens to B cell follicles in non-human primates through immune complex or protein nanoparticle formulations

immunology more details view paper
  • Downloaded 749 times
  • Download rankings, all-time:
    • Site-wide: 59,387
    • In immunology: 1,889
  • Year to date:
    • Site-wide: 181,077
  • Since beginning of last month:
    • Site-wide: 114,628

An efficient lentiviral CRISPRi approach to silence genes in primary human monocytes

immunology more details view paper
  • Downloaded 740 times
  • Download rankings, all-time:
    • Site-wide: 60,577
    • In immunology: 2,133
  • Year to date:
    • Site-wide: 40,292
  • Since beginning of last month:
    • Site-wide: 54,336

Disassembly of HIV envelope glycoprotein trimer immunogens is driven by antibodies elicited via immunization

immunology more details view paper
  • Downloaded 656 times
  • Download rankings, all-time:
    • Site-wide: 71,822
    • In immunology: 2,202
  • Year to date:
    • Site-wide: 56,499
  • Since beginning of last month:
    • Site-wide: 135,987

Vaccine-induced protection from homologous Tier 2 simian-human immunodeficiency virus challenge in nonhuman primates

immunology more details view paper
  • Downloaded 653 times
  • Download rankings, all-time:
    • Site-wide: 72,209
    • In immunology: 2,258
  • Year to date:
    • Site-wide: 200,301
  • Since beginning of last month:
    • Site-wide: 62,478

DOCK2 sets the threshold for entry into the virtual memory CD8+ T cell compartment by negatively regulating tonic TCR triggering

immunology more details view paper
  • Downloaded 518 times
  • Download rankings, all-time:
    • Site-wide: 96,319
    • In immunology: 3,018
  • Year to date:
    • Site-wide: 170,209
  • Since beginning of last month:
    • Site-wide: 76,388

Reprogramming brain immunosurveillance with engineered cytokines

bioengineering more details view paper
  • Downloaded 459 times
  • Download rankings, all-time:
    • Site-wide: 110,039
    • In bioengineering: 2,569
  • Year to date:
    • Site-wide: 12,455
  • Since beginning of last month:
    • Site-wide: 10,741

Identification of highly cross-reactive mimotopes for a public T cell response in murine melanoma

immunology more details view paper
  • Downloaded 417 times
  • Download rankings, all-time:
    • Site-wide: 120,658
    • In immunology: 3,800
  • Year to date:
    • Site-wide: 14,752
  • Since beginning of last month:
    • Site-wide: 97,304

Erythrocyte-targeted immunomodulatory antigens enabled by in vivo selection of D-peptides

bioengineering more details view paper
  • Downloaded 399 times
  • Download rankings, all-time:
    • Site-wide: 125,437
    • In bioengineering: 2,473
  • Year to date:
    • Site-wide: 110,862
  • Since beginning of last month:
    • Site-wide: 160,470

Eradication of tumors with pre-existing antigenic heterogeneity by vaccine-mediated co-engagement of CAR T and endogenous T-cells

immunology more details view paper
  • Downloaded 310 times
  • Download rankings, all-time:
    • Site-wide: 151,778
    • In immunology: None
  • Year to date:
    • Site-wide: 23,838
  • Since beginning of last month:
    • Site-wide: 5,038

Changes at V2 apex of HIV-1 Clade C trimer enhance elicitation of autologous neutralizing and broad V1V2-scaffold antibodies

immunology more details view paper
  • Downloaded 243 times
  • Download rankings, all-time:
    • Site-wide: 171,182
    • In immunology: 5,209
  • Year to date:
    • Site-wide: 141,524
  • Since beginning of last month:
    • Site-wide: 172,249

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