Author: Leslie A Lange

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Preprints

Recovery of trait heritability from whole genome sequence data

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  • Site-wide: 623
  • In genetics: 17
• Year to date:
  • Site-wide: 1,907
• Since beginning of last month:
  • Site-wide: 1,423

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

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  • Site-wide: 993
  • In genomics: 93
• Year to date:
  • Site-wide: 1,422
• Since beginning of last month:
  • Site-wide: 1,398

Trans-ethnic and ancestry-specific blood-cell genetics in 746,667 individuals from 5 global populations

• Downloaded 2,264 times
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  • Site-wide: 5,836
  • In genetics: 279
• Year to date:
  • Site-wide: 4,386
• Since beginning of last month:
  • Site-wide: 2,861

The Polygenic and Monogenic Basis of Blood Traits and Diseases

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  • Site-wide: 7,240
  • In genetic and genomic medicine: 20
• Year to date:
  • Site-wide: 23,527
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  • Site-wide: 18,715

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

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  • Site-wide: 7,969
  • In genetics: 387
• Year to date:
  • Site-wide: None
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PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

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  • Site-wide: 9,448
  • In genetics: 464
• Year to date:
  • Site-wide: 80,032
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  • Site-wide: 77,425

Trans-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

• Downloaded 980 times
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  • Site-wide: 20,279
  • In genetic and genomic medicine: 61
• Year to date:
  • Site-wide: 6,816
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  • Site-wide: 7,252

Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation

• Downloaded 798 times
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  • Site-wide: 27,100
  • In genetics: 1,350
• Year to date:
  • Site-wide: 26,541
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  • Site-wide: 45,487

The Trans-Ancestral Genomic Architecture of Glycaemic Traits

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  • Site-wide: 31,900
  • In genetics: 1,583
• Year to date:
  • Site-wide: 15,168
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  • Site-wide: 11,650

Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9

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  • Site-wide: 43,327
  • In genetics: 2,088
• Year to date:
  • Site-wide: 59,941
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  • Site-wide: None

Rare coding variants in 35 genes associate with circulating lipid levels: a multi-ancestry analysis of 170,000 exomes

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  • Site-wide: 49,209
  • In genetics: 2,351
• Year to date:
  • Site-wide: 3,768
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  • Site-wide: None

Meta-analysis of exome array data identifies six novel genetic loci for lung function

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  • Site-wide: 52,664
  • In genetics: 2,505
• Year to date:
  • Site-wide: 85,583
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  • Site-wide: 66,940

Whole genome sequencing association analysis of quantitative red blood cell phenotypes: the NHLBI TOPMed program

• Downloaded 378 times
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  • Site-wide: 66,491
  • In hematology: 40
• Year to date:
  • Site-wide: 4,762
• Since beginning of last month:
  • Site-wide: 4,829

find-tfbs: a tool to identify functional non-coding variants associated with complex human traits using open chromatin maps and phased whole-genome sequences

• Downloaded 138 times
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  • Site-wide: 114,447
  • In genomics: 6,394
• Year to date:
  • Site-wide: 46,684
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  • Site-wide: 57,696

Presence and Transmission of Mitochondrial Heteroplasmic Mutations in Human Populations of European and African Ancestry

• Downloaded 118 times
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  • Site-wide: 118,188
  • In genetics: 5,098
• Year to date:
  • Site-wide: 77,888
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  • Site-wide: 92,344

Genetic Underpinnings of Regional Adiposity Distribution in African Americans: Assessments from the Jackson Heart Study

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  • Site-wide: 125,876
  • In genetic and genomic medicine: 584
• Year to date:
  • Site-wide: 90,155
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  • Site-wide: 102,984