Author: John C Chambers

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Preprints

Genetic analysis of over one million people identifies 535 novel loci for blood pressure.

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Identification of type 2 diabetes loci in 433,540 East Asian individuals

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Genetic discovery and translational decision support from exome sequencing of 20,791 type 2 diabetes cases and 24,440 controls from five ancestries

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PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

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Novel blood pressure locus and gene discovery using GWAS and expression datasets from blood and the kidney

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Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation

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Trans-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

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Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes

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The Trans-Ancestral Genomic Architecture of Glycaemic Traits

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Proof of concept for quantitative urine NMR metabolomics pipeline for large-scale epidemiology and genetics

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Alcohol consumption is associated with widespread changes in blood DNA methylation: analysis of cross-sectional and longitudinal data

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Data Resource Profile: Understanding the patterns and determinants of health in South Asians - South Asia Biobank

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Low uptake of COVID-19 prevention behaviours and high socioeconomic impact of lockdown measures in South Asia: evidence from a large-scale multi-country surveillance programme

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The iHealth-T2D study: Statistical analysis plan for a cluster randomised controlled trial with intensive family based lifestyle modification programme to reduce type 2 diabetes risk amongst South Asians.

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The iHealth-T2D study: rationale and design of a cluster randomised trial for prevention of Type 2 Diabetes amongst South Asians with central obesity and prediabetes

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