Author: Benjamin F Cravatt

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Preprints

A competitive activity-based protein profiling platform yields cell wall synthesis inhibitors active against replicating and non-replicating Mycobacterium tuberculosis

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An activity-guided map of electrophile-cysteine interactions in primary human immune cells

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Electrophilic PROTACs that degrade nuclear proteins by engaging DCAF16

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ABHD17 enzymes regulate dynamic plasma membrane palmitoylation and N-Ras-dependent cancer growth

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Chemical inhibition of ENL/AF9 YEATS domains in acute leukemia

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Single-cell profiling and SCOPE-seq reveal the lineage dynamics of adult neurogenesis and NOTUM as a key V-SVZ regulator

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Integrative x-ray structure and molecular modeling for the rationalization of procaspase-8 inhibitor potency and selectivity

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Targeting Glioblastoma Signaling and Metabolism with A Re-Purposed Brain-Penetrant Drug

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Translation Attenuation by Minocycline Increases Lifespan and Improves Proteostasis in Old Post-Stress-Responsive Organisms

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ABHD4-dependent developmental anoikis protects the prenatal brain from pathological insults

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