Author: Shane Crotty

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Preprints

Immunological memory to SARS-CoV-2 assessed for up to eight months after infection

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  • Site-wide: 119
  • In immunology: 3
• Year to date:
  • Site-wide: 1,153
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  • Site-wide: 1,770

Negligible impact of SARS-CoV-2 variants on CD4+ and CD8+ T cell reactivity in COVID-19 exposed donors and vaccinees.

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  • Site-wide: 338
  • In immunology: 19
• Year to date:
  • Site-wide: 1,216
• Since beginning of last month:
  • Site-wide: 1,836

Humoral and cellular immune memory to four COVID-19 vaccines

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  • Site-wide: 877
  • In immunology: None
• Year to date:
  • Site-wide: 65
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  • Site-wide: 77

Low dose mRNA-1273 COVID-19 vaccine generates durable T cell memory and antibodies enhanced by pre-existing crossreactive T cell memory

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  • Site-wide: 1,705
  • In infectious diseases: 497
• Year to date:
  • Site-wide: 11,657
• Since beginning of last month:
  • Site-wide: 28,341

SARS-CoV-2 vaccination induces immunological memory able to cross-recognize variants from Alpha to Omicron

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  • Site-wide: 1,925
  • In immunology: 76
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  • Site-wide: 277
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  • Site-wide: 6,226

Omicron BA.1 and BA.2 neutralizing activity elicited by a comprehensive panel of human vaccines

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  • Site-wide: 6,312
  • In immunology: None
• Year to date:
  • Site-wide: 371
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  • Site-wide: 529

Comprehensive analysis of T cell immunodominance and immunoprevalence of SARS-CoV-2 epitopes in COVID-19 cases

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  • Site-wide: 6,318
  • In immunology: 234
• Year to date:
  • Site-wide: 30,782
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  • Site-wide: 45,158

CD4+ follicular helper-like T cells are key players in anti-tumor immunity

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  • Site-wide: 8,236
  • In immunology: 309
• Year to date:
  • Site-wide: 16,804
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  • Site-wide: 25,029

Long-lasting germinal center responses to a priming immunization with continuous proliferation and somatic mutation

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  • Site-wide: 14,280
  • In immunology: 645
• Year to date:
  • Site-wide: 2,321
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  • Site-wide: 6,884

Distinguishing COVID-19 infection and vaccination history by T cell reactivity

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  • Site-wide: 15,237
  • In immunology: 538
• Year to date:
  • Site-wide: 9,640
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  • Site-wide: 60,213

Single-cell lineage trajectories and chromatin regulators that initialize antiviral CD8 T cell ontogeny

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  • Site-wide: 17,776
  • In immunology: 722
• Year to date:
  • Site-wide: 9,895
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  • Site-wide: 10,721

AI-guided discovery of the invariant host response to viral pandemics

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  • Site-wide: 19,945
  • In bioinformatics: 2,277
• Year to date:
  • Site-wide: 27,147
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  • Site-wide: 20,583

Slow delivery immunization enhances HIV neutralizing antibody and germinal center responses via modulation of immunodominance

• Downloaded 1,280 times
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  • Site-wide: 23,417
  • In immunology: 778
• Year to date:
  • Site-wide: 164,802
• Since beginning of last month:
  • Site-wide: 157,020

Differential T cell reactivity to seasonal coronaviruses and SARS-CoV-2 in community and health care workers

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  • Site-wide: 27,951
  • In infectious diseases: 2,644
• Year to date:
  • Site-wide: 36,230
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  • Site-wide: 29,225

Evidence that recurrent Group A streptococcus tonsillitis is an immunosusceptibility disease involving antibody deficiency and aberrant Tfh cells

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  • Site-wide: 30,735
  • In immunology: 999
• Year to date:
  • Site-wide: 121,482
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  • Site-wide: 100,338

Mucosal and systemic responses to SARS-CoV-2 vaccination in infection naive and experienced individuals

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  • Site-wide: 31,381
  • In immunology: 1,193
• Year to date:
  • Site-wide: 2,384
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  • Site-wide: 24,565

From Structure to Sequence: Identification of polyclonal antibody families using cryoEM

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  • Site-wide: 33,580
  • In immunology: 1,119
• Year to date:
  • Site-wide: 34,762
• Since beginning of last month:
  • Site-wide: 55,529

Increased peripheral blood neutrophil activation phenotypes and NETosis in critically ill COVID-19 patients

• Downloaded 972 times
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  • Site-wide: 35,543
  • In allergy and immunology: 104
• Year to date:
  • Site-wide: 66,325
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  • Site-wide: 72,081

Normal human lymph node T follicular helper cells and germinal center B cells accessed via fine needle aspirations

• Downloaded 952 times
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  • Site-wide: 36,676
  • In immunology: 1,163
• Year to date:
  • Site-wide: 142,325
• Since beginning of last month:
  • Site-wide: 150,190

Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM

• Downloaded 841 times
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  • Site-wide: 44,148
  • In immunology: 1,496
• Year to date:
  • Site-wide: 43,979
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  • Site-wide: 38,275

NVX-CoV2373 vaccination induces functional SARS-CoV-2-specific CD4+ and CD8+ T cell responses

• Downloaded 764 times
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  • Site-wide: 50,779
  • In immunology: None
• Year to date:
  • Site-wide: 2,657
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  • Site-wide: 5,549

B cells expressing authentic naive human VRC01-class BCRs can be primed and recruited to germinal centers in multiple independent mouse models

• Downloaded 755 times
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  • Site-wide: 51,555
  • In immunology: 1,570
• Year to date:
  • Site-wide: 124,135
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  • Site-wide: 123,013

Targeting HIV Env immunogens to B cell follicles in non-human primates through immune complex or protein nanoparticle formulations

• Downloaded 722 times
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  • Site-wide: 54,977
  • In immunology: 1,636
• Year to date:
  • Site-wide: 172,603
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  • Site-wide: 151,319

Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques

• Downloaded 707 times
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  • Site-wide: 56,641
  • In immunology: 1,934
• Year to date:
  • Site-wide: 28,744
• Since beginning of last month:
  • Site-wide: 30,481

Profiling Transcription Initiation in Peripheral Leukocytes Reveals Severity-Associated Cis-Regulatory Elements in Critical COVID-19

• Downloaded 486 times
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  • Site-wide: 90,808
  • In genomics: 6,116
• Year to date:
  • Site-wide: 32,132
• Since beginning of last month:
  • Site-wide: 38,156

Vaccine genetics of IGHV1-2 VRC01-class broadly neutralizing antibody precursor naive human B cells

• Downloaded 385 times
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  • Site-wide: 114,388
  • In immunology: 3,379
• Year to date:
  • Site-wide: 93,479
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  • Site-wide: 118,297

Design and validation of HIV peptide pools for detection of HIV-specific CD4+ and CD8+ T cells

• Downloaded 100 times
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  • Site-wide: 186,039
  • In hiv aids: None
• Year to date:
  • Site-wide: 47,970
• Since beginning of last month:
  • Site-wide: 9,475