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Author: Eleanor Sanderson

Rankings

  • All-time downloads: 19,933 (rank: 11,694 (tie) )
  • Categories:
    • bioinformatics: 894 (rank: 19,800 (tie) )
    • cardiovascular medicine: 1,453 (rank: 364 )
    • endocrinology: 253 (rank: 1,275 (tie) )
    • epidemiology: 7,318 (rank: 2,367 )
    • genetic and genomic medicine: 357 (rank: 10,217 (tie) )
    • genetics: 9,127 (rank: 2,095 )
    • oncology: 217 (rank: 5,224 (tie) )
    • rheumatology: 314 (rank: 1,130 (tie) )

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Preprints

Interpretation of mendelian randomization using one measure of an exposure that varies over time.

epidemiology more details view paper

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Cross-platform genetic discovery of small molecule products of metabolism and application to clinical outcomes

genetics more details view paper
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    • Site-wide: 5,458
    • In genetics: 216
  • Year to date:
    • Site-wide: 7,848
  • Since beginning of last month:
    • Site-wide: 13,788

Within-family studies for Mendelian randomization: avoiding dynastic, assortative mating, and population stratification biases

genetics more details view paper
  • Downloaded 2,362 times
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    • Site-wide: 7,781
    • In genetics: 332
  • Year to date:
    • Site-wide: 31,894
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    • Site-wide: 49,150

Mendelian randomisation for mediation analysis: current methods and challenges for implementation

genetics more details view paper
  • Downloaded 2,133 times
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    • Site-wide: 9,030
    • In genetics: 373
  • Year to date:
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An examination of multivariable Mendelian randomization in the single sample and two-sample summary data settings.

epidemiology more details view paper
  • Downloaded 1,633 times
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    • Site-wide: 13,429
    • In epidemiology: 972
  • Year to date:
    • Site-wide: 81,976
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Testing and Correcting for Weak and Pleiotropic Instruments in Two-Sample Multivariable Mendelian Randomisation

genetics more details view paper
  • Downloaded 1,135 times
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    • Site-wide: 23,444
    • In genetics: 1,027
  • Year to date:
    • Site-wide: 13,450
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    • Site-wide: 13,437

Apolipoprotein B underlies the causal relationship of circulating blood lipids with coronary heart disease

cardiovascular medicine more details view paper
  • Downloaded 989 times
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    • Site-wide: 28,862
    • In cardiovascular medicine: 46
  • Year to date:
    • Site-wide: 101,920
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    • Site-wide: 136,588

MR-TRYX: A Mendelian randomization framework that exploits horizontal pleiotropy to infer novel causal pathways

bioinformatics more details view paper
  • Downloaded 894 times
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    • Site-wide: 33,508
    • In bioinformatics: 3,648
  • Year to date:
    • Site-wide: 82,925
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    • Site-wide: 79,248

Using genetic instruments to estimate interactions in Mendelian Randomization studies

epidemiology more details view paper
  • Downloaded 846 times
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    • Site-wide: 36,282
    • In epidemiology: 1,907
  • Year to date:
    • Site-wide: 34,407
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Can the impact of childhood adiposity on disease risk be reversed? A Mendelian randomization study

epidemiology more details view paper
  • Downloaded 810 times
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    • Site-wide: 38,702
    • In epidemiology: 1,996
  • Year to date:
    • Site-wide: 103,337
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    • Site-wide: 116,616

Exploring and mitigating potential bias when genetic instrumental variables are associated with multiple non-exposure traits in Mendelian randomization

epidemiology more details view paper
  • Downloaded 652 times
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    • Site-wide: 52,384
    • In epidemiology: 2,508
  • Year to date:
    • Site-wide: 42,748
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    • Site-wide: 30,962

Mendelian randomisation analysis of the effect of educational attainment and cognitive ability on smoking behaviour

epidemiology more details view paper
  • Downloaded 613 times
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    • Site-wide: 56,968
    • In epidemiology: 2,665
  • Year to date:
    • Site-wide: 145,928
  • Since beginning of last month:
    • Site-wide: 143,277

Interaction-based Mendelian randomization with measured and unmeasured gene-by-covariate interactions

epidemiology more details view paper
  • Downloaded 502 times
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    • Site-wide: 72,503
    • In epidemiology: 3,219
  • Year to date:
    • Site-wide: 39,595
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    • Site-wide: 42,388

The use of negative control outcomes in Mendelian Randomisation to detect potential population stratification or selection bias.

genetics more details view paper
  • Downloaded 491 times
  • Download rankings, all-time:
    • Site-wide: 74,264
    • In genetics: 3,150
  • Year to date:
    • Site-wide: 78,818
  • Since beginning of last month:
    • Site-wide: 93,695

Effects of apolipoprotein B on the lifespan and risks of major disease including type 2 diabetes: a Mendelian randomization analysis using outcomes in first-degree relatives

epidemiology more details view paper
  • Downloaded 475 times
  • Download rankings, all-time:
    • Site-wide: 77,101
    • In epidemiology: 3,388
  • Year to date:
    • Site-wide: 63,012
  • Since beginning of last month:
    • Site-wide: 131,416

Risk factors mediating the effect of body-mass index and waist-to-hip ratio on cardiovascular outcomes: Mendelian randomization analysis

cardiovascular medicine more details view paper
  • Downloaded 464 times
  • Download rankings, all-time:
    • Site-wide: 79,033
    • In cardiovascular medicine: 154
  • Year to date:
    • Site-wide: 69,396
  • Since beginning of last month:
    • Site-wide: 129,201

Adiposity, metabolites, and colorectal cancer risk: Mendelian randomization study

epidemiology more details view paper
  • Downloaded 409 times
  • Download rankings, all-time:
    • Site-wide: 89,968
    • In epidemiology: 3,850
  • Year to date:
    • Site-wide: 121,863
  • Since beginning of last month:
    • Site-wide: 142,201

A phenome-wide multi-directional Mendelian randomization analysis of atrial fibrillation

epidemiology more details view paper
  • Downloaded 372 times
  • Download rankings, all-time:
    • Site-wide: 98,222
    • In epidemiology: 4,195
  • Year to date:
    • Site-wide: 51,668
  • Since beginning of last month:
    • Site-wide: 112,566

Dominant role of abdominal adiposity in circulating lipoprotein, lipid, and metabolite levels in UK Biobank: Mendelian randomization study

epidemiology more details view paper
  • Downloaded 331 times
  • Download rankings, all-time:
    • Site-wide: 108,063
    • In epidemiology: 4,580
  • Year to date:
    • Site-wide: 29,409
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    • Site-wide: 54,115

The impact of education inequality on rheumatoid arthritis risk is mediated by smoking and body mass index: mendelian randomization study

rheumatology more details view paper
  • Downloaded 314 times
  • Download rankings, all-time:
    • Site-wide: 112,550
    • In rheumatology: 110
  • Year to date:
    • Site-wide: 31,770
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    • Site-wide: 65,171

Obesity as a cause of kidney disease - insights from Mendelian randomisation studies

endocrinology more details view paper
  • Downloaded 253 times
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    • Site-wide: 128,426
    • In endocrinology: 130
  • Year to date:
    • Site-wide: 76,055
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    • Site-wide: 91,351

Deciphering how early life adiposity influences breast cancer risk using Mendelian randomization

epidemiology more details view paper
  • Downloaded 248 times
  • Download rankings, all-time:
    • Site-wide: 129,908
    • In epidemiology: 5,452
  • Year to date:
    • Site-wide: 43,803
  • Since beginning of last month:
    • Site-wide: 32,335

A multivariable Mendelian randomisation study exploring the direct effects of nicotine on health compared with the other constituents of tobacco smoke: Implications for e-cigarette use

epidemiology more details view paper
  • Downloaded 226 times
  • Download rankings, all-time:
    • Site-wide: 135,465
    • In epidemiology: 5,653
  • Year to date:
    • Site-wide: 49,231
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    • Site-wide: 77,126

Estimating the effect of lipids on IGF axis and subsequent breast cancer risk

oncology more details view paper
  • Downloaded 217 times
  • Download rankings, all-time:
    • Site-wide: 137,829
    • In oncology: 431
  • Year to date:
    • Site-wide: 124,536
  • Since beginning of last month:
    • Site-wide: 112,314

Using multivariable Mendelian randomization to estimate the causal effect of bone mineral density on osteoarthritis risk, independent of body mass index

genetic and genomic medicine more details view paper
  • Downloaded 179 times
  • Download rankings, all-time:
    • Site-wide: 146,738
    • In genetic and genomic medicine: 892
  • Year to date:
    • Site-wide: 65,525
  • Since beginning of last month:
    • Site-wide: 58,527

Exploring the relationship between schizophrenia and cardiovascular disease: A genetic correlation and multivariable Mendelian randomization study

genetic and genomic medicine more details view paper
  • Downloaded 178 times
  • Download rankings, all-time:
    • Site-wide: 146,837
    • In genetic and genomic medicine: 893
  • Year to date:
    • Site-wide: 65,669
  • Since beginning of last month:
    • Site-wide: 54,024

Navigating sample overlap, winner's curse and weak instrument bias in Mendelian randomization studies using the UK Biobank

epidemiology more details view paper
  • Downloaded 126 times
  • Download rankings, all-time:
    • Site-wide: 156,469
    • In epidemiology: 6,464
  • Year to date:
    • Site-wide: 93,725
  • Since beginning of last month:
    • Site-wide: 82,447

Associations of insomnia on pregnancy and perinatal outcomes: Findings from Mendelian randomization and conventional observational studies in up to 356,069 women

epidemiology more details view paper
  • Downloaded 75 times
  • Download rankings, all-time:
    • Site-wide: 162,148
    • In epidemiology: 6,667
  • Year to date:
    • Site-wide: 135,604
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    • Site-wide: 25,431

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