Author: Henning Tiemeier

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Preprints

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

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  • Site-wide: 1,011
  • In genetics: 26
• Year to date:
  • Site-wide: 46,816
• Since beginning of last month:
  • Site-wide: 73,020

Genome-wide Analysis of Insomnia (N=1,331,010) Identifies Novel Loci and Functional Pathways

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  • Site-wide: 2,126
  • In genetics: 67
• Year to date:
  • Site-wide: 22,658
• Since beginning of last month:
  • Site-wide: 23,487

GWAS meta-analysis (N=279,930) identifies new genes and functional links to intelligence

• Downloaded 5,354 times
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  • Site-wide: 2,148
  • In genetics: 69
• Year to date:
  • Site-wide: 20,595
• Since beginning of last month:
  • Site-wide: None

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

• Downloaded 3,604 times
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  • Site-wide: 3,740
  • In genetics: 130
• Year to date:
  • Site-wide: 42,696
• Since beginning of last month:
  • Site-wide: 72,920

Genome-wide association analyses of chronotype in 697,828 individuals provides new insights into circadian rhythms in humans and links to disease

• Downloaded 2,402 times
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  • Site-wide: 6,692
  • In genetics: 293
• Year to date:
  • Site-wide: 40,794
• Since beginning of last month:
  • Site-wide: 44,001

GWAS Meta-Analysis of Neuroticism (N=449,484) Identifies Novel Genetic Loci and Pathways

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  • Site-wide: 6,992
  • In genetics: 310
• Year to date:
  • Site-wide: 44,710
• Since beginning of last month:
  • Site-wide: 38,901

Minimal phenotyping yields GWAS hits of reduced specificity for major depression

• Downloaded 2,111 times
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  • Site-wide: 8,085
  • In genetics: 353
• Year to date:
  • Site-wide: 43,149
• Since beginning of last month:
  • Site-wide: 61,982

Genetic Associations with Subjective Well-Being Also Implicate Depression and Neuroticism

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  • Site-wide: 10,710
  • In genetics: 475
• Year to date:
  • Site-wide: 93,740
• Since beginning of last month:
  • Site-wide: 73,209

Genome-wide association analyses in >119,000 individuals identifies thirteen morningness and two sleep duration loci

• Downloaded 1,659 times
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  • Site-wide: 11,530
  • In genetics: 519
• Year to date:
  • Site-wide: 114,518
• Since beginning of last month:
  • Site-wide: None

GWAS in 446,118 European adults identifies 78 genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates

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  • Site-wide: 13,008
  • In genetics: 589
• Year to date:
  • Site-wide: 98,461
• Since beginning of last month:
  • Site-wide: 72,827

Sex-Dependent Shared and Non-Shared Genetic Architecture Across Mood and Psychotic Disorders

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  • Site-wide: 15,849
  • In genetics: 729
• Year to date:
  • Site-wide: 5,309
• Since beginning of last month:
  • Site-wide: 6,907

Genetic studies of accelerometer-based sleep measures in 85,670 individuals yield new insights into human sleep behaviour

• Downloaded 1,325 times
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  • Site-wide: 16,120
  • In genetics: 739
• Year to date:
  • Site-wide: 84,652
• Since beginning of last month:
  • Site-wide: 72,826

Genetic Association Study of Childhood Aggression across raters, instruments and age

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  • Site-wide: 21,024
  • In genomics: 2,010
• Year to date:
  • Site-wide: 14,349
• Since beginning of last month:
  • Site-wide: 92,408

Genomic and phenomic insights from an atlas of genetic effects on DNA methylation

• Downloaded 970 times
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  • Site-wide: 25,548
  • In genetic and genomic medicine: 102
• Year to date:
  • Site-wide: 8,564
• Since beginning of last month:
  • Site-wide: 26,333

Phenome-wide investigation of health outcomes associated with genetic predisposition to loneliness

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  • Site-wide: 32,801
  • In genetics: 1,511
• Year to date:
  • Site-wide: 140,233
• Since beginning of last month:
  • Site-wide: 81,860

Association between DNA methylation and ADHD symptoms from birth to school age: A prospective meta-analysis

• Downloaded 679 times
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  • Site-wide: 41,890
  • In genetics: 1,882
• Year to date:
  • Site-wide: 55,570
• Since beginning of last month:
  • Site-wide: 90,664

Genetic analysis of mitochondrial DNA copy number and associated traits identifies loci implicated in nucleotide metabolism, platelet activation, and megakaryocyte proliferation, and reveals a causal association of mitochondrial function with mortality

• Downloaded 586 times
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  • Site-wide: 50,494
  • In genetics: 2,242
• Year to date:
  • Site-wide: 6,779
• Since beginning of last month:
  • Site-wide: 19,932

Epigenome-wide change and variation in DNA methylation from birth to late adolescence

• Downloaded 548 times
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  • Site-wide: 54,928
  • In genomics: 4,133
• Year to date:
  • Site-wide: 68,276
• Since beginning of last month:
  • Site-wide: 30,640

Genome-wide association meta-analysis of childhood and adolescent internalising symptoms

• Downloaded 525 times
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  • Site-wide: 57,778
  • In psychiatry and clinical psychology: 198
• Year to date:
  • Site-wide: 25,261
• Since beginning of last month:
  • Site-wide: 27,188

Genetic variation in the Major Histocompatibility Complex and association with depression

• Downloaded 444 times
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  • Site-wide: 69,496
  • In genetics: 3,067
• Year to date:
  • Site-wide: 134,975
• Since beginning of last month:
  • Site-wide: None

Teacher-rated aggression and co-occurring problems and behaviors among schoolchildren: A comparison of four population-based European cohorts

• Downloaded 424 times
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  • Site-wide: 72,797
  • In epidemiology: 3,148
• Year to date:
  • Site-wide: 63,414
• Since beginning of last month:
  • Site-wide: 27,656

Novel DNA methylation sites of glucose and insulin homeostasis: an integrative cross-omics analysis

• Downloaded 357 times
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  • Site-wide: 85,293
  • In genomics: 5,497
• Year to date:
  • Site-wide: 150,514
• Since beginning of last month:
  • Site-wide: None

A genome-wide association study of total child psychiatric problems scores

• Downloaded 354 times
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  • Site-wide: 85,737
  • In psychiatry and clinical psychology: 315
• Year to date:
  • Site-wide: 65,240
• Since beginning of last month:
  • Site-wide: 55,122

Combined polygenic risk scores of different psychiatric traits predict general and specific psychopathology in childhood

• Downloaded 345 times
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  • Site-wide: 87,607
  • In psychiatry and clinical psychology: 326
• Year to date:
  • Site-wide: 33,570
• Since beginning of last month:
  • Site-wide: 47,401

DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan

• Downloaded 267 times
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  • Site-wide: 105,248
  • In genetics: 4,487
• Year to date:
  • Site-wide: 102,721
• Since beginning of last month:
  • Site-wide: 54,211

Meta-analysis of epigenome-wide associations between DNA methylation at birth and childhood cognitive skills.

• Downloaded 227 times
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  • Site-wide: 115,382
  • In developmental biology: 3,091
• Year to date:
  • Site-wide: 44,335
• Since beginning of last month:
  • Site-wide: 46,130

Identifying Causative Mechanisms Linking Early-Life Stress to Psycho-Cardio-Metabolic Multi-Morbidity: The EarlyCause Project

• Downloaded 198 times
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  • Site-wide: 122,464
  • In neuroscience: 18,726
• Year to date:
  • Site-wide: 114,122
• Since beginning of last month:
  • Site-wide: 56,173

The bidirectional causal effects of brain morphology across the life course and risk of Alzheimers disease: A cross-cohort comparison and Mendelian randomization meta-analysis

• Downloaded 188 times
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  • Site-wide: 124,932
  • In genetic and genomic medicine: 659
• Year to date:
  • Site-wide: 32,530
• Since beginning of last month:
  • Site-wide: 109,813

Prenatal and Childhood Adverse Events and Child Brain Morphology: A Population-Based Study

• Downloaded 144 times
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  • Site-wide: 135,044
  • In epidemiology: 5,589
• Year to date:
  • Site-wide: 44,182
• Since beginning of last month:
  • Site-wide: 14,590

Epigenome-wide contributions to individual differences in childhood phenotypes: A GREML approach

• Downloaded 94 times
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  • Site-wide: 144,834
  • In genetic and genomic medicine: 826
• Year to date:
  • Site-wide: 66,777
• Since beginning of last month:
  • Site-wide: 37,638

Long-term association of pregnancy and maternal brain structure: the Rotterdam Study

• Downloaded 93 times
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  • Site-wide: 144,983
  • In neuroscience: 21,914
• Year to date:
  • Site-wide: 67,776
• Since beginning of last month:
  • Site-wide: 29,872

Association between prenatal alcohol exposure and children's facial shape. A prospective population-based cohort study

• Downloaded 45 times
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  • Site-wide: 150,519
  • In pediatrics: 293
• Year to date:
  • Site-wide: 113,893
• Since beginning of last month:
  • Site-wide: 38,081

Internalizing and externalizing behaviors in school-aged children are related to state anxiety during magnetic resonance imaging

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  • Site-wide: 153,947
  • In radiology and imaging: 355
• Year to date:
  • Site-wide: 154,014
• Since beginning of last month:
  • Site-wide: 25,963