Author: Tõnu Esko

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Preprints

Unraveling the polygenic architecture of complex traits using blood eQTL meta-analysis

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  • Site-wide: 812
  • In genomics: 60
• Year to date:
  • Site-wide: 1,210
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  • Site-wide: 1,130

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

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  • Site-wide: 3,662
  • In genetics: 128
• Year to date:
  • Site-wide: 41,273
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  • Site-wide: 40,179

Genome-wide association study of over 40,000 bipolar disorder cases provides new insights into the underlying biology

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  • Site-wide: 5,154
  • In psychiatry and clinical psychology: 20
• Year to date:
  • Site-wide: 1,503
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  • Site-wide: 5,424

Trans-ethnic and ancestry-specific blood-cell genetics in 746,667 individuals from 5 global populations

• Downloaded 2,686 times
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  • Site-wide: 5,525
  • In genetics: 238
• Year to date:
  • Site-wide: 5,344
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  • Site-wide: 7,868

Ultra-rare disruptive and damaging mutations influence educational attainment in the general population

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  • Site-wide: 6,834
  • In genetics: 306
• Year to date:
  • Site-wide: 103,386
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  • Site-wide: 74,095

Cell specific eQTL analysis without sorting cells

• Downloaded 2,013 times
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  • Site-wide: 8,431
  • In genetics: 368
• Year to date:
  • Site-wide: 128,985
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  • Site-wide: 132,349

A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

• Downloaded 1,823 times
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  • Site-wide: 9,781
  • In genetics: 441
• Year to date:
  • Site-wide: 64,228
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  • Site-wide: 105,036

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

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  • Site-wide: 10,678
  • In genetics: 482
• Year to date:
  • Site-wide: 59,622
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  • Site-wide: 51,600

Genome-wide association study provides new insights into the genetic architecture and pathogenesis of heart failure

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  • Site-wide: 13,089
  • In genetics: 606
• Year to date:
  • Site-wide: 100,102
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  • Site-wide: 95,638

Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility

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  • Site-wide: 16,978
  • In genomics: 1,682
• Year to date:
  • Site-wide: 110,362
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  • Site-wide: 137,213

Haplotype sharing provides insights into fine-scale population history and disease in Finland

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  • Site-wide: 19,466
  • In genetics: 914
• Year to date:
  • Site-wide: 80,230
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  • Site-wide: 106,178

Mega-analysis of 31,396 individuals from 6 countries uncovers strong gene-environment interaction for human fertility

• Downloaded 1,051 times
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  • Site-wide: 22,131
  • In genomics: 2,121
• Year to date:
  • Site-wide: 105,437
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  • Site-wide: 118,533

An epigenome-wide association study of educational attainment (n = 10,767)

• Downloaded 1,008 times
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  • Site-wide: 23,525
  • In genetics: 1,093
• Year to date:
  • Site-wide: 96,058
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  • Site-wide: 112,127

Shared Genetic Risk between Eating Disorder- and Substance-Use-Related Phenotypes: Evidence from Genome-Wide Association Studies

• Downloaded 771 times
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  • Site-wide: 34,361
  • In genetics: 1,584
• Year to date:
  • Site-wide: 23,517
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  • Site-wide: 74,236

Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms

• Downloaded 770 times
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  • Site-wide: 34,389
  • In genetics: 1,586
• Year to date:
  • Site-wide: 140,481
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  • Site-wide: 136,983

Functional and evolutionary impact of polymorphic inversions in the human genome

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  • Site-wide: 35,228
  • In genomics: 2,987
• Year to date:
  • Site-wide: 114,146
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  • Site-wide: 146,399

Genome-wide Association Study of Clinical Features in the Schizophrenia Psychiatric Genomics Consortium: Confirmation of Polygenic Effect on Negative Symptoms

• Downloaded 725 times
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  • Site-wide: 37,394
  • In genetics: 1,716
• Year to date:
  • Site-wide: 105,455
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  • Site-wide: 116,926

Mendelian randomisation identifies alternative splicing of the FAS death receptor as a mediator of severe COVID-19

• Downloaded 539 times
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  • Site-wide: 54,592
  • In infectious diseases: 3,083
• Year to date:
  • Site-wide: 6,755
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  • Site-wide: 5,383

Polygenic prediction of breast cancer: comparison of genetic predictors and implications for screening

• Downloaded 526 times
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  • Site-wide: 56,117
  • In genetics: 2,502
• Year to date:
  • Site-wide: 121,131
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  • Site-wide: 112,794

Multi-ancestry analysis of gene-sleep interactions in 126,926 individuals identifies multiple novel blood lipid loci that contribute to our understanding of sleep-associated adverse blood lipid profile

• Downloaded 514 times
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  • Site-wide: 57,685
  • In genomics: 4,287
• Year to date:
  • Site-wide: 140,389
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  • Site-wide: 141,958

Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure

• Downloaded 257 times
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  • Site-wide: 105,319
  • In genomics: 6,204
• Year to date:
  • Site-wide: 78,298
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  • Site-wide: 41,096