Author: Howard J. Edenberg

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Preprints

Genomewide association study identifies 30 loci associated with bipolar disorder

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Genome wide meta-analysis identifies genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders.

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  • Site-wide: 2,128
  • In genomics: 223
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Psychiatric Genomics: An Update and an Agenda

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Genome-wide association study of over 40,000 bipolar disorder cases provides new insights into the underlying biology

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  • Site-wide: 6,812
  • In psychiatry and clinical psychology: 23
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  • Site-wide: 1,288
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  • Site-wide: 650

Trans-ancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

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  • Site-wide: 8,122
  • In genetics: 373
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Genome-wide association study meta-analysis of the Alcohol Use Disorder Identification Test (AUDIT) in two population-based cohorts (N=141,932)

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Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder

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  • In genetics: 699
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Meta-analysis of problematic alcohol use in 435,563 individuals identifies 29 risk variants and yields insights into biology, pleiotropy and causality

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Genetic Data Can Lead to Medical Discrimination: Opioid Use Disorder as a Cautionary Tale

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  • Site-wide: 28,210
  • In addiction medicine: 6
• Year to date:
  • Site-wide: 7,380
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Leveraging genome-wide data to investigate differences between opioid use vs. opioid dependence in 41,176 individuals from the Psychiatric Genomics Consortium

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  • Site-wide: 31,065
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Shared Genetic Risk between Eating Disorder- and Substance-Use-Related Phenotypes: Evidence from Genome-Wide Association Studies

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  • Site-wide: 32,400
  • In genetics: 1,571
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Evidence of causal effect of major depression on alcohol dependence: Findings from the Psychiatric Genomics Consortium

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Examining sex-differentiated genetic effects across neuropsychiatric and behavioral traits

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Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders and known risk factors

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  • Site-wide: 52,188
  • In genetic and genomic medicine: 166
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  • Site-wide: 10,437
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  • Site-wide: 8,567

Multivariate GWAS elucidates the genetic architecture of alcohol consumption and misuse, corrects biases, and reveals novel associations with disease

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  • Site-wide: 69,273
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Analysis of whole genome-transcriptomic organization in brain to identify genes associated with alcoholism

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  • In neuroscience: 12,197
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Polygenic Prediction of Substance Use Disorders in Clinical and Population Samples

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The Addiction Genetic Factor a(g): A Unitary Genetic Vulnerability Characterizes Substance Use Disorders and Their Associations with Common Correlates

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  • Site-wide: 83,172
  • In addiction medicine: 43
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Allele-Specific Expression and High-Throughput Reporter Assay Reveal Functional Variants in Human Brains with Alcohol Use Disorders

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  • Site-wide: 89,424
  • In neuroscience: 13,826
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Multi-omics integration analysis identifies novel genes for alcoholism with potential link to neurodegenerative diseases

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  • Site-wide: 94,468
  • In genomics: 5,799
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  • Site-wide: 41,773

Investigation of convergent and divergent genetic influences underlying schizophrenia and alcohol use disorder

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  • Site-wide: 99,406
  • In genetic and genomic medicine: 399
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Genes identified in rodent studies of alcohol intake are enriched for heritability of human substance use

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  • Site-wide: 133,588
  • In genetics: 5,473
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