Author: Jennifer A. Smith

Downloads per author, site-wide

Preprints

Test performance evaluation of SARS-CoV-2 serological assays

• Downloaded 40,332 times
• Download rankings, all-time:
  • Site-wide: 174
  • In infectious diseases: 68
• Year to date:
  • Site-wide: 747
• Since beginning of last month:
  • Site-wide: 24,476

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

• Downloaded 8,465 times
• Download rankings, all-time:
  • Site-wide: 1,202
  • In genomics: 97
• Year to date:
  • Site-wide: 3,936
• Since beginning of last month:
  • Site-wide: 57,857

Heterogeneity in polygenic scores for common human traits

• Downloaded 3,935 times
• Download rankings, all-time:
  • Site-wide: 3,368
  • In genetics: 115
• Year to date:
  • Site-wide: 13,056
• Since beginning of last month:
  • Site-wide: 3,566

Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

• Downloaded 3,352 times
• Download rankings, all-time:
  • Site-wide: 4,200
  • In genetics: 154
• Year to date:
  • Site-wide: 44,104
• Since beginning of last month:
  • Site-wide: 19,454

Inherited Causes of Clonal Hematopoiesis of Indeterminate Potential in TOPMed Whole Genomes

• Downloaded 3,094 times
• Download rankings, all-time:
  • Site-wide: 4,719
  • In genomics: 488
• Year to date:
  • Site-wide: 10,255
• Since beginning of last month:
  • Site-wide: 88,996

Genetic insights into the biological mechanisms governing human ovarian ageing

• Downloaded 1,818 times
• Download rankings, all-time:
  • Site-wide: 10,237
  • In sexual and reproductive health: 10
• Year to date:
  • Site-wide: 1,515
• Since beginning of last month:
  • Site-wide: 256

Genetic Associations with Subjective Well-Being Also Implicate Depression and Neuroticism

• Downloaded 1,755 times
• Download rankings, all-time:
  • Site-wide: 10,794
  • In genetics: 477
• Year to date:
  • Site-wide: 89,166
• Since beginning of last month:
  • Site-wide: 40,395

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

• Downloaded 1,750 times
• Download rankings, all-time:
  • Site-wide: 10,834
  • In genetics: 478
• Year to date:
  • Site-wide: 54,153
• Since beginning of last month:
  • Site-wide: 19,806

Trans-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

• Downloaded 1,478 times
• Download rankings, all-time:
  • Site-wide: 13,875
  • In genetic and genomic medicine: 62
• Year to date:
  • Site-wide: 6,258
• Since beginning of last month:
  • Site-wide: 9,608

Genome-wide association studies identify 137 loci for DNA methylation biomarkers of ageing

• Downloaded 1,443 times
• Download rankings, all-time:
  • Site-wide: 14,420
  • In genetics: 657
• Year to date:
  • Site-wide: 7,515
• Since beginning of last month:
  • Site-wide: 124,932

Population sequencing data reveal a compendium of mutational processes in human germline

• Downloaded 1,430 times
• Download rankings, all-time:
  • Site-wide: 14,627
  • In genetics: 668
• Year to date:
  • Site-wide: 23,491
• Since beginning of last month:
  • Site-wide: 51,204

Genome-wide association and functional studies identify 46 novel loci for alcohol consumption and suggest common genetic mechanisms with neuropsychiatric disorders

• Downloaded 1,256 times
• Download rankings, all-time:
  • Site-wide: 17,750
  • In genetics: 821
• Year to date:
  • Site-wide: 65,187
• Since beginning of last month:
  • Site-wide: 23,267

Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation

• Downloaded 993 times
• Download rankings, all-time:
  • Site-wide: 25,110
  • In genetics: 1,140
• Year to date:
  • Site-wide: 25,488
• Since beginning of last month:
  • Site-wide: 119,413

Efficient variant set mixed model association tests for continuous and binary traits in large-scale whole genome sequencing studies

• Downloaded 858 times
• Download rankings, all-time:
  • Site-wide: 30,945
  • In genetics: 1,420
• Year to date:
  • Site-wide: 125,838
• Since beginning of last month:
  • Site-wide: 114,212

The Potential Impact of Interruptions to HIV Services: A Modelling Case Study for South Africa

• Downloaded 818 times
• Download rankings, all-time:
  • Site-wide: 32,977
  • In epidemiology: 1,723
• Year to date:
  • Site-wide: 62,684
• Since beginning of last month:
  • Site-wide: 95,682

Loss-of-function genomic variants with impact on liver-related blood traits highlight potential therapeutic targets for cardiovascular disease

• Downloaded 799 times
• Download rankings, all-time:
  • Site-wide: 34,147
  • In genomics: 2,910
• Year to date:
  • Site-wide: 79,007
• Since beginning of last month:
  • Site-wide: 38,986

Single cell transcriptome analysis defines heterogeneity of the adult murine pancreatic ductal tree

• Downloaded 759 times
• Download rankings, all-time:
  • Site-wide: 36,770
  • In bioinformatics: 3,973
• Year to date:
  • Site-wide: 14,006
• Since beginning of last month:
  • Site-wide: 95,024

Leveraging Gene Co-expression Patterns to Infer Trait-Relevant Tissues in Genome-wide Association Studies

• Downloaded 717 times
• Download rankings, all-time:
  • Site-wide: 39,715
  • In genetics: 1,783
• Year to date:
  • Site-wide: 127,642
• Since beginning of last month:
  • Site-wide: None

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

• Downloaded 692 times
• Download rankings, all-time:
  • Site-wide: 41,605
  • In genomics: 3,358
• Year to date:
  • Site-wide: 107,152
• Since beginning of last month:
  • Site-wide: 57,718

Bayesian Shrinkage Estimation of High Dimensional Causal Mediation Effects in Omics Studies

• Downloaded 662 times
• Download rankings, all-time:
  • Site-wide: 44,112
  • In epidemiology: 2,161
• Year to date:
  • Site-wide: 92,406
• Since beginning of last month:
  • Site-wide: 27,062

Exome chip meta-analysis elucidates the genetic architecture of rare coding variants in smoking and drinking behavior

• Downloaded 589 times
• Download rankings, all-time:
  • Site-wide: 51,215
  • In genetics: 2,259
• Year to date:
  • Site-wide: 144,178
• Since beginning of last month:
  • Site-wide: None

A system for phenotype harmonization in the NHLBI Trans-Omics for Precision Medicine (TOPMed) Program

• Downloaded 499 times
• Download rankings, all-time:
  • Site-wide: 62,408
  • In genetics: 2,758
• Year to date:
  • Site-wide: 23,513
• Since beginning of last month:
  • Site-wide: 44,323

A non-APOE polygenic score for Alzheimer's disease and APOE-ε4 have independent associations with dementia in the Health and Retirement Study

• Downloaded 494 times
• Download rankings, all-time:
  • Site-wide: 63,046
  • In epidemiology: 2,824
• Year to date:
  • Site-wide: 71,392
• Since beginning of last month:
  • Site-wide: 120,936

Robust, flexible, and scalable tests for Hardy-Weinberg Equilibrium across diverse ancestries

• Downloaded 369 times
• Download rankings, all-time:
  • Site-wide: 84,481
  • In bioinformatics: 7,586
• Year to date:
  • Site-wide: 73,204
• Since beginning of last month:
  • Site-wide: 125,111

Novel DNA methylation sites of glucose and insulin homeostasis: an integrative cross-omics analysis

• Downloaded 357 times
• Download rankings, all-time:
  • Site-wide: 86,807
  • In genomics: 5,563
• Year to date:
  • Site-wide: 152,880
• Since beginning of last month:
  • Site-wide: None

Association of mitochondrial DNA copy number with cardiometabolic diseases in a large cross-sectional study of multiple ancestries

• Downloaded 334 times
• Download rankings, all-time:
  • Site-wide: 91,832
  • In epidemiology: 3,876
• Year to date:
  • Site-wide: 64,303
• Since beginning of last month:
  • Site-wide: 120,547

Role of Rare and Low Frequency Variants in Gene-Alcohol Interactions on Plasma Lipid Levels

• Downloaded 332 times
• Download rankings, all-time:
  • Site-wide: 92,294
  • In epidemiology: 3,893
• Year to date:
  • Site-wide: 101,640
• Since beginning of last month:
  • Site-wide: 56,968

Whole Genome Sequence Association Analysis of Fasting Glucose and Fasting Insulin Levels in Diverse Cohorts from the NHLBI TOPMed Program

• Downloaded 290 times
• Download rankings, all-time:
  • Site-wide: 101,913
  • In genetic and genomic medicine: 488
• Year to date:
  • Site-wide: 20,255
• Since beginning of last month:
  • Site-wide: 53,124

Evaluation of the causal effect of fibrinogen on incident coronary heart disease via Mendelian randomization

• Downloaded 275 times
• Download rankings, all-time:
  • Site-wide: 105,487
  • In genetics: 4,475
• Year to date:
  • Site-wide: 151,606
• Since beginning of last month:
  • Site-wide: None

Stabilization of p53 by microRNAs in HPV-positive cervical cancer cells

• Downloaded 144 times
• Download rankings, all-time:
  • Site-wide: 137,063
  • In cancer biology: 4,214
• Year to date:
  • Site-wide: 96,090
• Since beginning of last month:
  • Site-wide: 84,648