Author: Jennifer A. Smith

Downloads per author, site-wide

Preprints

Test performance evaluation of SARS-CoV-2 serological assays

• Downloaded 38,986 times
• Download rankings, all-time:
  • Site-wide: 147
  • In infectious diseases: 61
• Year to date:
  • Site-wide: 569
• Since beginning of last month:
  • Site-wide: 560

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

• Downloaded 8,181 times
• Download rankings, all-time:
  • Site-wide: 1,049
  • In genomics: 95
• Year to date:
  • Site-wide: 2,365
• Since beginning of last month:
  • Site-wide: 5,829

Heterogeneity in polygenic scores for common human traits

• Downloaded 3,673 times
• Download rankings, all-time:
  • Site-wide: 3,125
  • In genetics: 120
• Year to date:
  • Site-wide: 19,853
• Since beginning of last month:
  • Site-wide: 21,650

Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

• Downloaded 3,261 times
• Download rankings, all-time:
  • Site-wide: 3,708
  • In genetics: 152
• Year to date:
  • Site-wide: 43,073
• Since beginning of last month:
  • Site-wide: 89,134

Inherited Causes of Clonal Hematopoiesis of Indeterminate Potential in TOPMed Whole Genomes

• Downloaded 2,917 times
• Download rankings, all-time:
  • Site-wide: 4,319
  • In genomics: 478
• Year to date:
  • Site-wide: 7,020
• Since beginning of last month:
  • Site-wide: 7,556

Genetic Associations with Subjective Well-Being Also Implicate Depression and Neuroticism

• Downloaded 1,713 times
• Download rankings, all-time:
  • Site-wide: 9,507
  • In genetics: 453
• Year to date:
  • Site-wide: 78,666
• Since beginning of last month:
  • Site-wide: 85,472

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

• Downloaded 1,660 times
• Download rankings, all-time:
  • Site-wide: 9,936
  • In genetics: 472
• Year to date:
  • Site-wide: 66,595
• Since beginning of last month:
  • Site-wide: 48,818

Population sequencing data reveal a compendium of mutational processes in human germline

• Downloaded 1,303 times
• Download rankings, all-time:
  • Site-wide: 14,248
  • In genetics: 697
• Year to date:
  • Site-wide: 19,909
• Since beginning of last month:
  • Site-wide: 15,502

Genome-wide association studies identify 137 loci for DNA methylation biomarkers of ageing

• Downloaded 1,206 times
• Download rankings, all-time:
  • Site-wide: 16,014
  • In genetics: 790
• Year to date:
  • Site-wide: 5,625
• Since beginning of last month:
  • Site-wide: 5,004

Genome-wide association and functional studies identify 46 novel loci for alcohol consumption and suggest common genetic mechanisms with neuropsychiatric disorders

• Downloaded 1,198 times
• Download rankings, all-time:
  • Site-wide: 16,175
  • In genetics: 795
• Year to date:
  • Site-wide: 54,761
• Since beginning of last month:
  • Site-wide: 75,315

Trans-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

• Downloaded 1,083 times
• Download rankings, all-time:
  • Site-wide: 18,782
  • In genetic and genomic medicine: 69
• Year to date:
  • Site-wide: 8,359
• Since beginning of last month:
  • Site-wide: 11,151

Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation

• Downloaded 877 times
• Download rankings, all-time:
  • Site-wide: 25,528
  • In genetics: 1,229
• Year to date:
  • Site-wide: 20,712
• Since beginning of last month:
  • Site-wide: 12,997

Efficient variant set mixed model association tests for continuous and binary traits in large-scale whole genome sequencing studies

• Downloaded 840 times
• Download rankings, all-time:
  • Site-wide: 27,072
  • In genetics: 1,306
• Year to date:
  • Site-wide: 95,012
• Since beginning of last month:
  • Site-wide: 103,243

The Potential Impact of Interruptions to HIV Services: A Modelling Case Study for South Africa

• Downloaded 754 times
• Download rankings, all-time:
  • Site-wide: 31,515
  • In epidemiology: 1,608
• Year to date:
  • Site-wide: 56,667
• Since beginning of last month:
  • Site-wide: 52,328

Loss-of-function genomic variants with impact on liver-related blood traits highlight potential therapeutic targets for cardiovascular disease

• Downloaded 747 times
• Download rankings, all-time:
  • Site-wide: 31,905
  • In genomics: 2,831
• Year to date:
  • Site-wide: 73,808
• Since beginning of last month:
  • Site-wide: 89,423

Leveraging Gene Co-expression Patterns to Infer Trait-Relevant Tissues in Genome-wide Association Studies

• Downloaded 707 times
• Download rankings, all-time:
  • Site-wide: 34,419
  • In genetics: 1,650
• Year to date:
  • Site-wide: 79,381
• Since beginning of last month:
  • Site-wide: 79,669

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

• Downloaded 667 times
• Download rankings, all-time:
  • Site-wide: 37,193
  • In genomics: 3,164
• Year to date:
  • Site-wide: 78,283
• Since beginning of last month:
  • Site-wide: 108,611

Single cell transcriptome analysis defines heterogeneity of the adult murine pancreatic ductal tree

• Downloaded 638 times
• Download rankings, all-time:
  • Site-wide: 39,455
  • In bioinformatics: 4,298
• Year to date:
  • Site-wide: 8,445
• Since beginning of last month:
  • Site-wide: 9,054

Bayesian Shrinkage Estimation of High Dimensional Causal Mediation Effects in Omics Studies

• Downloaded 614 times
• Download rankings, all-time:
  • Site-wide: 41,335
  • In epidemiology: 1,963
• Year to date:
  • Site-wide: 100,323
• Since beginning of last month:
  • Site-wide: 87,540

Genetic insights into the biological mechanisms governing human ovarian ageing

• Downloaded 587 times
• Download rankings, all-time:
  • Site-wide: 43,827
  • In sexual and reproductive health: 19
• Year to date:
  • Site-wide: 2,523
• Since beginning of last month:
  • Site-wide: 8,602

Exome chip meta-analysis elucidates the genetic architecture of rare coding variants in smoking and drinking behavior

• Downloaded 577 times
• Download rankings, all-time:
  • Site-wide: 44,661
  • In genetics: 2,090
• Year to date:
  • Site-wide: 117,030
• Since beginning of last month:
  • Site-wide: 101,691

A non-APOE polygenic score for Alzheimer's disease and APOE-ε4 have independent associations with dementia in the Health and Retirement Study

• Downloaded 448 times
• Download rankings, all-time:
  • Site-wide: 59,915
  • In epidemiology: 2,592
• Year to date:
  • Site-wide: 53,313
• Since beginning of last month:
  • Site-wide: 49,590

Novel DNA methylation sites of glucose and insulin homeostasis: an integrative cross-omics analysis

• Downloaded 352 times
• Download rankings, all-time:
  • Site-wide: 75,383
  • In genomics: 5,094
• Year to date:
  • Site-wide: 127,227
• Since beginning of last month:
  • Site-wide: 127,212

Robust, flexible, and scalable tests for Hardy-Weinberg Equilibrium across diverse ancestries

• Downloaded 321 times
• Download rankings, all-time:
  • Site-wide: 81,371
  • In bioinformatics: 7,433
• Year to date:
  • Site-wide: 58,349
• Since beginning of last month:
  • Site-wide: 44,066

Role of Rare and Low Frequency Variants in Gene-Alcohol Interactions on Plasma Lipid Levels

• Downloaded 301 times
• Download rankings, all-time:
  • Site-wide: 85,475
  • In epidemiology: 3,519
• Year to date:
  • Site-wide: 79,724
• Since beginning of last month:
  • Site-wide: 86,258

Association of mitochondrial DNA copy number with cardiometabolic diseases in a large cross-sectional study of multiple ancestries

• Downloaded 293 times
• Download rankings, all-time:
  • Site-wide: 87,174
  • In epidemiology: 3,580
• Year to date:
  • Site-wide: 41,606
• Since beginning of last month:
  • Site-wide: 59,777

A system for phenotype harmonization in the NHLBI Trans-Omics for Precision Medicine (TOPMed) Program

• Downloaded 292 times
• Download rankings, all-time:
  • Site-wide: 87,458
  • In genetics: 3,944
• Year to date:
  • Site-wide: 51,222
• Since beginning of last month:
  • Site-wide: None

Evaluation of the causal effect of fibrinogen on incident coronary heart disease via Mendelian randomization

• Downloaded 269 times
• Download rankings, all-time:
  • Site-wide: 92,293
  • In genetics: 4,142
• Year to date:
  • Site-wide: 123,207
• Since beginning of last month:
  • Site-wide: 106,960

Whole Genome Sequence Association Analysis of Fasting Glucose and Fasting Insulin Levels in Diverse Cohorts from the NHLBI TOPMed Program

• Downloaded 184 times
• Download rankings, all-time:
  • Site-wide: 111,138
  • In genetic and genomic medicine: 490
• Year to date:
  • Site-wide: 13,079
• Since beginning of last month:
  • Site-wide: 33,800

Stabilization of p53 by microRNAs in HPV-positive cervical cancer cells

• Downloaded 113 times
• Download rankings, all-time:
  • Site-wide: 125,760
  • In cancer biology: 3,904
• Year to date:
  • Site-wide: 71,736
• Since beginning of last month:
  • Site-wide: 55,858