Author: Hyejung Won

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Preprints

Discovery Of The First Genome-Wide Significant Risk Loci For ADHD

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  • Site-wide: 1,009
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  • Site-wide: 5,978
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  • Site-wide: 10,741

Common risk variants identified in autism spectrum disorder

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  • Site-wide: 1,500
  • In genetics: 31
• Year to date:
  • Site-wide: 7,814
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  • Site-wide: 20,117

Genome wide meta-analysis identifies genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders.

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  • Site-wide: 3,272
  • In genomics: 280
• Year to date:
  • Site-wide: 13,869
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  • Site-wide: 32,839

De novo mutations in regulatory elements cause neurodevelopmental disorders

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  • Site-wide: 11,454
  • In genetics: 429
• Year to date:
  • Site-wide: 93,489
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  • Site-wide: 208,743

Widespread allelic heterogeneity in complex traits

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  • In genetics: 526
• Year to date:
  • Site-wide: 166,730
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Temporal analysis suggests a reciprocal relationship between 3D chromatin structure and transcription

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  • Site-wide: 23,134
  • In genomics: 2,031
• Year to date:
  • Site-wide: 43,318
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  • Site-wide: 25,806

A genome-wide association study for shared risk across major psychiatric disorders in a nation-wide birth cohort implicates fetal neurodevelopment as a key mediator

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  • Site-wide: 26,587
  • In genetics: 1,062
• Year to date:
  • Site-wide: 93,776
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  • Site-wide: 152,005

Neuronal and glial 3D chromatin architecture illustrates cellular etiology of brain disorders

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  • Site-wide: 26,581
  • In neuroscience: 3,205
• Year to date:
  • Site-wide: 153,067
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  • Site-wide: 102,036

Connecting gene regulatory relationships to neurobiological mechanisms of brain disorders

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  • Site-wide: 34,034
  • In neuroscience: 4,249
• Year to date:
  • Site-wide: 171,823
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  • Site-wide: 206,275

Integrative genomics identifies a convergent molecular subtype that links epigenomic with transcriptomic differences in autism

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  • Site-wide: 36,691
  • In genomics: 2,895
• Year to date:
  • Site-wide: 193,778
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  • Site-wide: 200,035

Social and non-social autism symptom and trait domains are genetically dissociable

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  • Site-wide: 37,900
  • In genetics: 1,505
• Year to date:
  • Site-wide: 118,969
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  • Site-wide: 43,513

Common genetic risk variants identified in the SPARK cohort implicate DDHD2 as a novel autism risk gene

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  • Site-wide: 46,892
  • In psychiatry and clinical psychology: 205
• Year to date:
  • Site-wide: 124,414
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  • Site-wide: 78,579

Schizophrenia-linked protein tSNARE1 regulates endolysosomal trafficking in cortical neurons

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  • Site-wide: 47,907
  • In neuroscience: 6,387
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  • Site-wide: 83,338
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  • Site-wide: 63,065

Expanding the Genetic Architecture of Nicotine Dependence and its Shared Genetics with Multiple Traits: Findings from the Nicotine Dependence GenOmics (iNDiGO) Consortium

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  • Site-wide: 63,952
  • In genomics: 4,425
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  • Site-wide: 119,814
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A response to Yurko et al: H-MAGMA, inheriting a shaky statistical foundation, yields excess false positives

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  • Site-wide: 71,977
  • In genomics: 4,812
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  • Site-wide: 149,147
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  • Site-wide: 103,566

FIREcaller: Detecting Frequently Interacting Regions from Hi-C Data

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  • Site-wide: 73,134
  • In bioinformatics: 6,827
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  • Site-wide: 118,715
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  • Site-wide: 143,014

Systematic investigation of allelic regulatory activity of schizophrenia-associated common variants

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  • Site-wide: 90,986
  • In genetic and genomic medicine: 678
• Year to date:
  • Site-wide: 2,199
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  • Site-wide: 6,209

The genetics of cortical organisation and development: a study of 2,347 neuroimaging phenotypes

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  • Site-wide: 93,428
  • In neuroscience: 14,880
• Year to date:
  • Site-wide: 4,970
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Chromatin architecture in addiction circuitry elucidates biological mechanisms underlying cigarette smoking and alcohol use traits.

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  • Site-wide: 101,638
  • In neuroscience: 14,888
• Year to date:
  • Site-wide: 146,247
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  • Site-wide: 56,611

Synthetic amyloid beta does not induce a robust transcriptional response in innate immune cell culture systems

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  • Site-wide: 115,558
  • In neuroscience: 16,895
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  • Site-wide: 58,296
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  • Site-wide: 36,932

Illuminating links between cis-regulators and trans-acting variants in the human prefrontal cortex

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  • Site-wide: 121,399
  • In genomics: 6,851
• Year to date:
  • Site-wide: 100,111
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  • Site-wide: 110,220

Multi-ancestry Genome-wide Association Study of Varicose Veins Reveals Polygenic Architecture, Genetic Overlap with Arterial and Venous Disease, and Novel Therapeutic Opportunities

• Downloaded 377 times
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  • Site-wide: 136,793
  • In cardiovascular medicine: 430
• Year to date:
  • Site-wide: 11,320
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  • Site-wide: 67,156

HIV integration in the human brain is linked to microglial activation and 3D genome remodeling

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  • Site-wide: 145,277
  • In neuroscience: 23,244
• Year to date:
  • Site-wide: 8,334
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  • Site-wide: 16,830

Chromatin loop dynamics during cellular differentiation are associated with changes to both anchor and internal regulatory features

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  • Site-wide: 181,257
  • In genomics: 9,012
• Year to date:
  • Site-wide: 7,911
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  • Site-wide: 19,172