Author: Laura D Howe

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Preprints

Within-family studies for Mendelian randomization: avoiding dynastic, assortative mating, and population stratification biases

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Mendelian randomisation for mediation analysis: current methods and challenges for implementation

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  • Site-wide: 8,313
  • In genetics: 364
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The causes and consequences of Alzheimer's disease: A Mendelian randomization analysis

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  • Site-wide: 20,267
  • In genetic and genomic medicine: 80
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Education, intelligence and Alzheimer's disease: Evidence from a multivariable two-sample Mendelian randomization study

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  • Site-wide: 22,159
  • In genetics: 1,014
• Year to date:
  • Site-wide: 110,765
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The Causal Effect Of Educational Attainment On Alzheimer's Disease: A Two-Sample Mendelian Randomization Study

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  • Site-wide: 33,223
  • In epidemiology: 1,715
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Using genetic instruments to estimate interactions in Mendelian Randomization studies

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  • Site-wide: 40,954
  • In epidemiology: 2,017
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Assessing the causal role of body mass index on cardiovascular health in young adults: Mendelian randomization and recall-by-genotype analyses

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  • Site-wide: 44,502
  • In epidemiology: 2,155
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Is disrupted sleep a risk factor for Alzheimers disease? Evidence from a two-sample Mendelian randomization analysis

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  • Site-wide: 50,338
  • In epidemiology: 2,345
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What explains the effect of education on cardiovascular disease? Applying Mendelian randomization to identify the consequences of education inequality

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  • In epidemiology: 2,657
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Is genetic liability to ADHD and ASD causally linked to educational attainment?

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  • Site-wide: 62,270
  • In genetics: 2,752
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The Causal Effects of Health Conditions and Risk Factors on Social and Socioeconomic Outcomes: Mendelian Randomization in UK Biobank

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  • Site-wide: 65,771
  • In public and global health: 905
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  • Site-wide: 93,692
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Effects of body mass index on relationship status, social contact, and socioeconomic position: Mendelian Randomization study in UK Biobank

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  • Site-wide: 66,114
  • In epidemiology: 2,893
• Year to date:
  • Site-wide: 134,210
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  • Site-wide: 83,063

Adverse childhood experiences: associations with educational attainment and adolescent health, and the role of family and socioeconomic factors. Analysis of a prospective cohort study.

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  • Site-wide: 77,413
  • In epidemiology: 3,300
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  • Site-wide: 102,860
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Sex differences in cardiometabolic traits at four life stages: cohort study with repeated metabolomics

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  • Site-wide: 78,437
  • In epidemiology: 3,340
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Educational inequalities in statin treatment for preventing cardiovascular disease: cross-sectional analysis of UK Biobank

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  • In epidemiology: 3,729
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Common health conditions in childhood and adolescence, school absence, and educational attainment: Mendelian randomization study

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  • Site-wide: 91,805
  • In epidemiology: 3,845
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  • Site-wide: 84,582
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The role of school enjoyment in the association between externalising and depressive symptoms and academic attainment: findings from a UK prospective cohort study

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  • Site-wide: 98,540
  • In epidemiology: 4,150
• Year to date:
  • Site-wide: 55,389
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Puberty timing and adiposity change across childhood and adolescence: disentangling cause and consequence

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  • Site-wide: 99,676
  • In epidemiology: 4,185
• Year to date:
  • Site-wide: 135,036
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Joint modelling of individual trajectories, within-individual variability and a later outcome: systolic blood pressure through childhood and left ventricular mass in early adulthood

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  • Site-wide: 99,914
  • In epidemiology: 4,192
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  • Site-wide: 107,215
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Interrogating structural inequalities in COVID-19 Mortality in England and Wales

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  • Site-wide: 104,329
  • In epidemiology: 4,357
• Year to date:
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Exploring the causal effects of genetic liability to ADHD and Autism on Alzheimer's disease

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  • Site-wide: 105,591
  • In genetics: 4,498
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  • Site-wide: 90,610
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Robust causal inference for long-term policy decisions: cost effectiveness of interventions for obesity using Mendelian randomization

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  • Site-wide: 107,342
  • In epidemiology: 4,473
• Year to date:
  • Site-wide: 67,647
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  • Site-wide: 112,219

The UK Coronavirus Job Retention Scheme and changes in diet, physical activity and sleep during the COVID-19 pandemic: Evidence from eight longitudinal studies

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  • Site-wide: 107,890
  • In epidemiology: 4,491
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  • Site-wide: 21,861
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  • Site-wide: 15,909

How does childhood maltreatment influence cardiovascular disease? A sequential causal mediation analysis

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  • Site-wide: 107,706
  • In epidemiology: 4,484
• Year to date:
  • Site-wide: 42,231
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Age at period cessation and trajectories of cardiovascular risk factors across mid and later life: a prospective cohort study

• Downloaded 255 times
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  • Site-wide: 108,220
  • In epidemiology: 4,516
• Year to date:
  • Site-wide: 140,904
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Epigenetic gestational age and trajectories of weight and height during childhood: a prospective cohort study

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  • Site-wide: 110,067
  • In genomics: 6,361
• Year to date:
  • Site-wide: 147,952
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Polygenic risk score for Alzheimer's disease and trajectories of cardiometabolic risk factors in children

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  • Site-wide: 111,852
  • In epidemiology: 4,658
• Year to date:
  • Site-wide: 134,516
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Causal effects of circulating cytokine concentrations on risk of Alzheimers disease: A bidirectional two-sample Mendelian randomization study

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  • Site-wide: 113,733
  • In genetic and genomic medicine: 577
• Year to date:
  • Site-wide: 45,193
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  • Site-wide: 40,712

The role of the metabolic profile in mediating the relationship between body mass index and left ventricular mass in adolescents: analysis of a prospective cohort study

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  • Site-wide: 119,324
  • In epidemiology: 4,991
• Year to date:
  • Site-wide: 115,024
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The bidirectional causal effects of brain morphology across the life course and risk of Alzheimers disease: A cross-cohort comparison and Mendelian randomization meta-analysis

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  • Site-wide: 124,952
  • In genetic and genomic medicine: 659
• Year to date:
  • Site-wide: 32,564
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  • Site-wide: 111,888

Testosterone and socioeconomic position: Mendelian Randomization in 306,248 men and women participants of UK Biobank

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  • Site-wide: 125,402
  • In epidemiology: 5,244
• Year to date:
  • Site-wide: 76,446
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Cross-sectional association of blood pressure variability and night-time dipping with cardiac structure in adolescents

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  • Site-wide: 133,052
  • In epidemiology: 5,514
• Year to date:
  • Site-wide: 69,717
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  • Site-wide: 49,000

Maternal prenatal anxiety and depression and trajectories of cardiometabolic risk factors across childhood and adolescence: a prospective cohort study

• Downloaded 146 times
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  • Site-wide: 134,548
  • In pediatrics: 234
• Year to date:
  • Site-wide: 43,449
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  • Site-wide: 49,455

Associations of socioeconomic position and adverse childhood experiences with health-related behaviour changes and changes to employment during the first COVID-19 lockdown in the UK

• Downloaded 146 times
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  • Site-wide: 134,601
  • In epidemiology: 5,566
• Year to date:
  • Site-wide: 43,523
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  • Site-wide: 112,330

Educational attainment as a modifier of the effect of polygenic scores for cardiovascular risk factors: cross-sectional and prospective analysis of UK Biobank

• Downloaded 121 times
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  • Site-wide: 139,948
  • In genetic and genomic medicine: 773
• Year to date:
  • Site-wide: 52,949
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  • Site-wide: 101,599

Mitochondrial DNA haplogroups and trajectories of cardiometabolic risk factors during childhood and adolescence: a prospective cohort study

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  • Site-wide: 140,503
  • In epidemiology: 5,790
• Year to date:
  • Site-wide: 89,481
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  • Site-wide: 105,646

Puberty Timing and Markers of Cardiovascular Structure and Function at 25 Years: A Prospective Cohort Study

• Downloaded 108 times
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  • Site-wide: 142,297
  • In epidemiology: 5,863
• Year to date:
  • Site-wide: 98,606
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  • Site-wide: 115,475

Establishing the causal role of intimate partner violence and abuse on depressive symptoms in young adults: a population-based cohort study

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  • Site-wide: 146,945
  • In epidemiology: 6,040
• Year to date:
  • Site-wide: 76,317
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  • Site-wide: 101,519

Categories of intimate partner violence and abuse (IPVA) among young women and men: Latent Class Analysis of psychological, physical, and sexual victimisation and perpetration in a UK birth cohort

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  • Site-wide: 154,087
  • In epidemiology: 6,351
• Year to date:
  • Site-wide: 154,022
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  • Site-wide: 32,796