Author: Ludmil B Alexandrov

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Preprints

Mutational signatures in esophageal squamous cell carcinoma from eight countries of varying incidence

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The Repertoire of Mutational Signatures in Human Cancer

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Germline determinants of the somatic mutation landscape in 2,642 cancer genomes

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Mutational signatures associated with tobacco smoking in human cancer

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The genomic and epigenomic evolutionary history of papillary renal cell carcinomas

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Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation

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SigProfilerMatrixGenerator: a tool for visualizing and exploring patterns of small mutational events

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Somatic mutational profiles and germline polygenic risk scores in human cancer

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Novel syngeneic animal model of tobacco-associated oral cancer reveals the activity of in situ anti-CTLA-4

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Uncovering novel mutational signatures by de novo extraction with SigProfilerExtractor

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Genomic evidence supports a clonal diaspora model for metastases of esophageal adenocarcinoma

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Generating realistic null hypothesis of cancer mutational landscapes using SigProfilerSimulator

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The APOBEC3A deaminase drives episodic mutagenesis in cancer cells

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Signatures of copy number alterations in human cancer

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