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Author: Gosia Trynka

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  • All-time downloads: 38,062 (rank: 1,103 out of 404,161)
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    • genetics: 24,443 (rank: 229 out of 36,792)
    • genomics: 4,196 (rank: 4,745 (tie) out of 42,763)
    • immunology: 9,423 (rank: 381 out of 23,479)

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Preprints

Partitioning heritability by functional category using GWAS summary statistics

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Regulatory variants explain much more heritability than coding variants across 11 common diseases

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Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types

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Defining Inflammatory Cell States in Rheumatoid Arthritis Joint Synovial Tissues by Integrating Single-cell Transcriptomics and Mass Cytometry

immunology more details view paper
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Association mapping of inflammatory bowel disease loci to single variant resolution

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Single Cell Transcriptomics And Flow Cytometry Reveal Disease-Associated Fibroblast Subsets In Rheumatoid Arthritis

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Genomic profiling of T cell activation reveals dependency of memory T cells on CD28 costimulation

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Genome-wide association studies suggest limited immune gene enrichment in schizophrenia compared to five autoimmune diseases

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Single-cell transcriptomics identifies an effectorness gradient shaping the response of CD4+ T cells to cytokines

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A positively selected, common, missense variant in FBN1 confers a 2.2 centimeter reduction of height in the Peruvian population

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Immune disease variants modulate gene expression in regulatory CD4+ T cells and inform drug targets

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Chromatin activity at GWAS loci identifies T cell states driving complex immune diseases

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Disentangling effects of colocalizing genomic annotations to functionally prioritize non-coding variants within complex trait loci

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Pathologically distinct fibroblast subsets drive inflammation and tissue damage in arthritis

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High dimensional analyses of cells dissociated from cryopreserved synovial tissue

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Tissue-specific Enrichment of Lymphoma Risk Loci in Regulatory Elements

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Using genetics to differentiate patients with similar symptoms: application to inflammatory arthritis in the rheumatology outpatient clinic

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