Author: André G. Uitterlinden

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Preprints

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

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  • Site-wide: 868
  • In genetics: 26
• Year to date:
  • Site-wide: 31,048
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  • Site-wide: 32,877

Genetic analysis of over one million people identifies 535 novel loci for blood pressure.

• Downloaded 3,082 times
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  • Site-wide: 3,975
  • In genetics: 168
• Year to date:
  • Site-wide: 54,308
• Since beginning of last month:
  • Site-wide: 72,291

Genome-wide association study identifies 48 common genetic variants associated with handedness

• Downloaded 2,567 times
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  • Site-wide: 5,158
  • In genetics: 235
• Year to date:
  • Site-wide: 22,289
• Since beginning of last month:
  • Site-wide: 26,556

Cell specific eQTL analysis without sorting cells

• Downloaded 2,004 times
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  • Site-wide: 7,430
  • In genetics: 350
• Year to date:
  • Site-wide: 102,684
• Since beginning of last month:
  • Site-wide: 86,803

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

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  • Site-wide: 8,388
  • In genetics: 393
• Year to date:
  • Site-wide: 87,764
• Since beginning of last month:
  • Site-wide: 88,900

Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

• Downloaded 1,717 times
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  • Site-wide: 9,405
  • In genetics: 450
• Year to date:
  • Site-wide: 83,091
• Since beginning of last month:
  • Site-wide: 88,598

Genetic Associations with Subjective Well-Being Also Implicate Depression and Neuroticism

• Downloaded 1,713 times
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  • Site-wide: 9,441
  • In genetics: 453
• Year to date:
  • Site-wide: 75,488
• Since beginning of last month:
  • Site-wide: 78,472

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

• Downloaded 1,660 times
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  • Site-wide: 9,872
  • In genetics: 469
• Year to date:
  • Site-wide: 64,880
• Since beginning of last month:
  • Site-wide: 45,358

Genetic Determinants of Cortical Structure (Thickness, Surface Area and Volumes) among Disease Free Adults in the CHARGE Consortium

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  • Site-wide: 11,920
  • In genetics: 580
• Year to date:
  • Site-wide: 26,077
• Since beginning of last month:
  • Site-wide: 18,277

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

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  • Site-wide: 12,517
  • In genetics: 616
• Year to date:
  • Site-wide: 86,829
• Since beginning of last month:
  • Site-wide: 65,768

Epigenome-wide association meta-analysis of DNA methylation with coffee and tea consumption

• Downloaded 1,334 times
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  • Site-wide: 13,659
  • In genomics: 1,451
• Year to date:
  • Site-wide: 20,083
• Since beginning of last month:
  • Site-wide: 20,426

A high-quality reference panel reveals the complexity and distribution of structural genome changes in a human population

• Downloaded 1,293 times
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  • Site-wide: 14,342
  • In genetics: 706
• Year to date:
  • Site-wide: 64,778
• Since beginning of last month:
  • Site-wide: 48,021

Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility

• Downloaded 1,243 times
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  • Site-wide: 15,227
  • In genomics: 1,578
• Year to date:
  • Site-wide: 87,318
• Since beginning of last month:
  • Site-wide: 120,296

Large-Scale Genome-Wide Meta Analysis of Polycystic Ovary Syndrome Suggests Shared Genetic Architecture for Different Diagnosis Criteria.

• Downloaded 1,064 times
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  • Site-wide: 19,165
  • In genetics: 930
• Year to date:
  • Site-wide: 81,376
• Since beginning of last month:
  • Site-wide: 74,051

An epigenome-wide association study of educational attainment (n = 10,767)

• Downloaded 996 times
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  • Site-wide: 21,077
  • In genetics: 1,012
• Year to date:
  • Site-wide: 62,438
• Since beginning of last month:
  • Site-wide: 61,290

Meta-GWAS Accuracy and Power (MetaGAP) calculator shows that hiding heritability is partially due to imperfect genetic correlations across studies

• Downloaded 964 times
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  • Site-wide: 22,071
  • In genetics: 1,064
• Year to date:
  • Site-wide: 95,417
• Since beginning of last month:
  • Site-wide: 112,372

Genetic Association Study of Childhood Aggression across raters, instruments and age

• Downloaded 898 times
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  • Site-wide: 24,513
  • In genomics: 2,340
• Year to date:
  • Site-wide: 17,202
• Since beginning of last month:
  • Site-wide: 11,120

Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways

• Downloaded 781 times
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  • Site-wide: 29,796
  • In genetics: 1,444
• Year to date:
  • Site-wide: 69,599
• Since beginning of last month:
  • Site-wide: 86,985

Novel blood pressure locus and gene discovery using GWAS and expression datasets from blood and the kidney

• Downloaded 751 times
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  • Site-wide: 31,472
  • In genomics: 2,814
• Year to date:
  • Site-wide: 94,111
• Since beginning of last month:
  • Site-wide: 108,316

Genomic and phenomic insights from an atlas of genetic effects on DNA methylation

• Downloaded 689 times
• Download rankings, all-time:
  • Site-wide: 35,394
  • In genetic and genomic medicine: 109
• Year to date:
  • Site-wide: 9,641
• Since beginning of last month:
  • Site-wide: 10,244

Novel genetic loci affecting facial shape variation in humans

• Downloaded 679 times
• Download rankings, all-time:
  • Site-wide: 36,113
  • In genomics: 3,104
• Year to date:
  • Site-wide: 87,182
• Since beginning of last month:
  • Site-wide: 88,872

Multiethnic Meta-analysis Identifies New Loci for Pulmonary Function

• Downloaded 607 times
• Download rankings, all-time:
  • Site-wide: 41,736
  • In genetics: 1,980
• Year to date:
  • Site-wide: 110,040
• Since beginning of last month:
  • Site-wide: 88,710

Multi-ancestry analysis of gene-sleep interactions in 126,926 individuals identifies multiple novel blood lipid loci that contribute to our understanding of sleep-associated adverse blood lipid profile

• Downloaded 506 times
• Download rankings, all-time:
  • Site-wide: 52,036
  • In genomics: 4,036
• Year to date:
  • Site-wide: 120,060
• Since beginning of last month:
  • Site-wide: 116,900

Meta-analysis of exome array data identifies six novel genetic loci for lung function

• Downloaded 476 times
• Download rankings, all-time:
  • Site-wide: 55,735
  • In genetics: 2,588
• Year to date:
  • Site-wide: 118,304
• Since beginning of last month:
  • Site-wide: 130,812

Novel DNA methylation sites of glucose and insulin homeostasis: an integrative cross-omics analysis

• Downloaded 352 times
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  • Site-wide: 74,880
  • In genomics: 5,076
• Year to date:
  • Site-wide: 127,494
• Since beginning of last month:
  • Site-wide: 125,877

Evaluation of the causal effect of fibrinogen on incident coronary heart disease via Mendelian randomization

• Downloaded 268 times
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  • Site-wide: 92,035
  • In genetics: 4,141
• Year to date:
  • Site-wide: 123,272
• Since beginning of last month:
  • Site-wide: 112,705

Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure

• Downloaded 210 times
• Download rankings, all-time:
  • Site-wide: 104,866
  • In genomics: 6,130
• Year to date:
  • Site-wide: 98,746
• Since beginning of last month:
  • Site-wide: 75,307