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Author: Rodolfo G Goya

Rankings

  • All-time downloads: 202,883 (rank: 639 )
  • Categories:
    • bioinformatics: 2,357 (rank: 8,941 )
    • cell biology: 9,775 (rank: 535 )
    • developmental biology: 122,732 (rank: 1 )
    • epidemiology: 11,659 (rank: 1,927 )
    • evolutionary biology: 5,889 (rank: 908 )
    • genetic and genomic medicine: 385 (rank: 13,820 (tie) )
    • genetics: 5,523 (rank: 4,307 )
    • genomics: 11,950 (rank: 2,055 )
    • molecular biology: 20,698 (rank: 61 )
    • neuroscience: 1,796 (rank: 20,481 (tie) )
    • physiology: 1,337 (rank: 1,012 (tie) )
    • public and global health: 79 (rank: 20,065 (tie) )
    • systems biology: 976 (rank: 6,561 (tie) )

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Preprints

YOUNG PLASMA REJUVENATES BLOOD DNA METHYLATION PROFILE, PROLONGS MEAN LIFESPAN AND IMPROVES HEALTH IN OLD RATS

bioinformatics more details view paper

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Reversing age: dual species measurement of epigenetic age with a single clock

developmental biology more details view paper
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    • Site-wide: 69
    • In developmental biology: 1
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    • Site-wide: 407
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Reversal of ageing- and injury-induced vision loss by Tet-dependent epigenetic reprogramming

molecular biology more details view paper
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    • Site-wide: 573
    • In molecular biology: 6
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Phenotypic Age: a novel signature of mortality and morbidity risk

epidemiology more details view paper
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Universal DNA methylation age across mammalian tissues

developmental biology more details view paper
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An epigenetic biomarker of aging for lifespan and healthspan

epidemiology more details view paper
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Transient non-integrative nuclear reprogramming promotes multifaceted reversal of aging in human cells

cell biology more details view paper
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    • Site-wide: 6,880
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Global changes in patterning, splicing and primate specific lncRNAs in autism brain

genomics more details view paper
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Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap

genomics more details view paper
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Multi-omic rejuvenation and lifespan extension upon exposure to youthful circulation

cell biology more details view paper
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    • Site-wide: 8,832
    • In cell biology: 199
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Epigenetic predictors of maximum lifespan and other life history traits in mammals

evolutionary biology more details view paper
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    • Site-wide: 10,343
    • In evolutionary biology: 277
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A mammalian methylation array for profiling methylation levels at conserved sequences

bioinformatics more details view paper
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    • Site-wide: 15,542
    • In bioinformatics: 1,680
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Genome-wide association studies identify 137 loci for DNA methylation biomarkers of ageing

genetics more details view paper
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    • Site-wide: 16,798
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OxPhos Dysfunction Causes Hypermetabolism and Reduces Lifespan in Cells and in Patients with Mitochondrial Diseases

cell biology more details view paper
  • Downloaded 1,553 times
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    • Site-wide: 19,251
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Small extracellular vesicles from young mice prevent frailty, improve healthspan and decrease epigenetic age in old mice.

physiology more details view paper
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    • Site-wide: 21,678
    • In physiology: 61
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A Multi-Omics and Bioenergetics Longitudinal Aging Dataset in Primary Human Fibroblasts with Mitochondrial Perturbations

cell biology more details view paper
  • Downloaded 1,385 times
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    • Site-wide: 23,118
    • In cell biology: 1,016
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Rapamycin treatment during development extends lifespan and healthspan

developmental biology more details view paper
  • Downloaded 1,382 times
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    • Site-wide: 23,197
    • In developmental biology: 524
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    • Site-wide: 2,059
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Incorporation of a nucleoside analog maps genome repair sites in post-mitotic human neurons

neuroscience more details view paper
  • Downloaded 1,373 times
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    • In neuroscience: 2,629
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Human Aging DNA Methylation Signatures are Conserved but Accelerated in Cultured Fibroblasts

cell biology more details view paper
  • Downloaded 1,350 times
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    • Site-wide: 24,058
    • In cell biology: 751
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    • Site-wide: 101,969
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Genome Methylation Predicts Age and Longevity of Bats

genomics more details view paper
  • Downloaded 1,308 times
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DNA Methylation Networks Underlying Mammalian Traits

evolutionary biology more details view paper
  • Downloaded 1,223 times
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    • Site-wide: 28,146
    • In evolutionary biology: 1,046
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Biological age is increased by stress and restored upon recovery

systems biology more details view paper
  • Downloaded 1,207 times
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    • Site-wide: 28,716
    • In systems biology: 709
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    • Site-wide: 3,475

Schizophrenia is characterized by age- and sex-specific effects on epigenetic aging

genomics more details view paper
  • Downloaded 1,162 times
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    • Site-wide: 30,513
    • In genomics: 2,702
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    • Site-wide: 6,455

An epigenome-wide association study of educational attainment (n = 10,767)

genetics more details view paper
  • Downloaded 1,098 times
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    • Site-wide: 33,375
    • In genetics: 1,303
  • Year to date:
    • Site-wide: 177,022
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    • Site-wide: 100,848

PRC2 clock: a universal biomarker of aging and rejuvenation

genomics more details view paper
  • Downloaded 949 times
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    • Site-wide: 41,688
    • In genomics: 4,593
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    • Site-wide: 3,764
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    • Site-wide: 4,317

Epigenetic clocks predict prevalence and incidence of leading causes of death and disease burden

genomics more details view paper
  • Downloaded 927 times
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    • Site-wide: 43,170
    • In genomics: 3,252
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    • Site-wide: 132,948
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    • Site-wide: 159,368

GWAS of epigenetic ageing rates in blood reveals a critical role for TERT

genetics more details view paper
  • Downloaded 904 times
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    • Site-wide: 44,869
    • In genetics: 1,721
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    • Site-wide: 207,765
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Hibernation slows epigenetic aging in yellow-bellied marmots

evolutionary biology more details view paper
  • Downloaded 904 times
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    • Site-wide: 44,819
    • In evolutionary biology: 1,779
  • Year to date:
    • Site-wide: 30,151
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    • Site-wide: 121,100

Epigenetic clock and methylation studies in dogs

developmental biology more details view paper
  • Downloaded 868 times
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    • Site-wide: 47,725
    • In developmental biology: 1,093
  • Year to date:
    • Site-wide: 23,776
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    • Site-wide: 24,464

Causal Epigenetic Age Uncouples Damage and Adaptation

genetics more details view paper
  • Downloaded 844 times
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    • Site-wide: 49,853
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  • Year to date:
    • Site-wide: 4,542
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    • Site-wide: 1,205

Divergent age-related methylation patterns in long and short-lived mammals

evolutionary biology more details view paper
  • Downloaded 777 times
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    • Site-wide: 56,274
    • In evolutionary biology: 2,740
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    • Site-wide: 5,185
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Genetic Loci and Metabolic States Associated With Murine Epigenetic Aging

genomics more details view paper
  • Downloaded 740 times
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    • In genomics: 4,349
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DNA methylation clocks show slower progression of aging in naked mole-rat queens

developmental biology more details view paper
  • Downloaded 720 times
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    • Site-wide: 62,962
    • In developmental biology: 1,499
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Epigenetic clock and methylation studies in cats

developmental biology more details view paper
  • Downloaded 715 times
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    • Site-wide: 63,571
    • In developmental biology: 1,444
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    • Site-wide: 151,547
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Aging the Brain: Multi-Region Methylation Principal Component Based Clock in the Context of Alzheimer's Disease

bioinformatics more details view paper
  • Downloaded 704 times
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    • In bioinformatics: 6,447
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A meta-analysis of genome-wide association studies of epigenetic age acceleration

genetics more details view paper
  • Downloaded 661 times
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    • Site-wide: 71,060
    • In genetics: 2,709
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Meta-analysis of genome-wide DNA methylation and integrative OMICs in human skeletal muscle

genetics more details view paper
  • Downloaded 635 times
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    • Site-wide: 74,908
    • In genetics: 2,895
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Association of 4 epigenetic clocks with measures of functional health, cognition, and all-cause mortality in The Irish Longitudinal Study on Ageing (TILDA)

genomics more details view paper
  • Downloaded 627 times
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    • Site-wide: 76,154
    • In genomics: 5,138
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    • Site-wide: 165,200

Pan-primate DNA methylation clocks

developmental biology more details view paper
  • Downloaded 615 times
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    • Site-wide: 78,058
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    • Site-wide: 41,925
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Castration delays epigenetic aging and feminises DNA methylation at androgen-regulated loci

developmental biology more details view paper
  • Downloaded 596 times
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    • Site-wide: 81,097
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A systematic evaluation of 41 DNA methylation predictors across 101 data preprocessing and normalization strategies highlights considerable variation in algorithm performance

genomics more details view paper
  • Downloaded 595 times
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    • Site-wide: 81,284
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Chronic Glucocorticoid Stress Reveals Increased Energy Expenditure and Accelerated Aging as Cellular Features of Allostatic Load

cell biology more details view paper
  • Downloaded 519 times
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    • Site-wide: 96,211
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Epigenetic clock and methylation study of oocytes from a bovine model of reproductive aging

developmental biology more details view paper
  • Downloaded 500 times
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    • Site-wide: 100,292
    • In developmental biology: 2,542
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    • Site-wide: 171,639
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    • Site-wide: 142,254

Epigenetic age provides insight into tissue origin in endometriosis

genetics more details view paper
  • Downloaded 494 times
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    • Site-wide: 101,694
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DNAmFitAge: Biological Age Indicator Incorporating Physical Fitness

genetic and genomic medicine more details view paper
  • Downloaded 484 times
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    • Site-wide: 104,109
    • In genetic and genomic medicine: 796
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Epigenetic clock and methylation studies in the rhesus macaque

developmental biology more details view paper
  • Downloaded 477 times
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    • Site-wide: 105,681
    • In developmental biology: 2,638
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Epigenomic signature of the progeroid Cockayne syndrome exposes distinct and common features with physiological ageing

molecular biology more details view paper
  • Downloaded 468 times
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    • Site-wide: 107,942
    • In molecular biology: 3,142
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The analysis of epigenomic evolution

evolutionary biology more details view paper
  • Downloaded 467 times
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    • Site-wide: 108,174
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    • Site-wide: 116,551

An epigenetic predictor of death captures multi-modal measures of brain health

neuroscience more details view paper
  • Downloaded 447 times
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    • Site-wide: 112,691
    • In neuroscience: 15,909
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    • Site-wide: 123,079

Development of epigenetic clocks for New Zealand livestock

genomics more details view paper
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    • Site-wide: 124,983
    • In genomics: 7,006
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Epigenetic clock and DNA methylation studies of roe deer in the wild

evolutionary biology more details view paper
  • Downloaded 384 times
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    • Site-wide: 129,858
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Epigenetic clock and methylation studies in vervet monkeys

developmental biology more details view paper
  • Downloaded 384 times
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    • Site-wide: 129,824
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    • Site-wide: 164,252
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    • Site-wide: 159,480

Assessing the causal role of epigenetic clocks in the development of multiple cancers: a Mendelian randomization study

epidemiology more details view paper
  • Downloaded 351 times
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    • Site-wide: 139,482
    • In epidemiology: 5,910
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    • Site-wide: 120,667

DNA methylation age analysis of rapamycin in common marmosets

developmental biology more details view paper
  • Downloaded 349 times
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    • Site-wide: 140,052
    • In developmental biology: 3,597
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Refining epigenetic prediction of chronological and biological age

genomics more details view paper
  • Downloaded 347 times
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    • Site-wide: 140,441
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    • Site-wide: 19,822
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Epigenetic models predict age and aging in plains zebras and other equids

developmental biology more details view paper
  • Downloaded 341 times
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    • Site-wide: 142,484
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    • Site-wide: 102,412
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    • Site-wide: 116,660

An epigenetic clock to estimate the age of living beluga whales

developmental biology more details view paper
  • Downloaded 328 times
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    • Site-wide: 146,378
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    • Site-wide: 162,670

Epigenetic clock and DNA methylation analysis of porcine models of aging and obesity

developmental biology more details view paper
  • Downloaded 323 times
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    • Site-wide: 147,790
    • In developmental biology: 3,909
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    • Site-wide: 136,061
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    • Site-wide: 105,993

Multi-tissue methylation clocks for age estimation in the common bottlenose dolphin

developmental biology more details view paper
  • Downloaded 305 times
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    • Site-wide: 153,285
    • In developmental biology: 4,142
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    • Site-wide: 103,499
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    • Site-wide: 51,898

The influence of biological and statistical properties of CpGs on epigenetic predictions of eighteen traits

genomics more details view paper
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    • Site-wide: 159,391
    • In genomics: 8,005
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Methylation studies in Peromyscus: aging, altitude adaptation, and monogamy

developmental biology more details view paper
  • Downloaded 280 times
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    • Site-wide: 160,590
    • In developmental biology: 4,145
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    • Site-wide: 150,326

Genome-wide DNA methylation and multi-omics study of human chondrocyte ontogeny and an epigenetic clock analysis of adult chondrocytes

molecular biology more details view paper
  • Downloaded 277 times
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    • Site-wide: 161,422
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    • Site-wide: 78,459
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Epigenetic profiling and incidence of disrupted development point to gastrulation as aging ground zero in Xenopus laevis

genetics more details view paper
  • Downloaded 270 times
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    • Site-wide: 163,707
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    • Site-wide: 29,504
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    • Site-wide: 7,925

DNA methylation clocks for clawed frogs reveal evolutionary conservation of epigenetic ageing

developmental biology more details view paper
  • Downloaded 244 times
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    • Site-wide: 170,964
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    • Site-wide: 34,287
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    • Site-wide: 13,016

Epigenetics and island-mainland divergence in an insectivorous small mammal

genomics more details view paper
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    • Site-wide: 175,356
    • In genomics: 8,851
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Epigenetic clock and methylation studies in gray short-tailed opossums

evolutionary biology more details view paper
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    • Site-wide: 181,240
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HIV, Pathology and epigenetic age acceleration in different human tissues

molecular biology more details view paper
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    • Site-wide: 187,354
    • In molecular biology: 5,481
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DNA methylation clock DNAmFitAge shows regular exercise is associated with slower aging and systemic adaptation

public and global health more details view paper
  • Downloaded 168 times
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    • Site-wide: 189,220
    • In public and global health: 3,043
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    • Site-wide: 93,917

Epigenome-wide meta-analysis of BMI in nine population-based cohorts: examining the utility of methylation as a biomarker of BMI

genetics more details view paper
  • Downloaded 119 times
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    • Site-wide: 198,239
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    • Site-wide: 81,318
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    • Site-wide: 26,214

DNA methylation age studies of humpback whales

developmental biology more details view paper
  • Downloaded 104 times
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    • Site-wide: 200,728
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