Author: Paul Shinn

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Preprints

The SARS-CoV-2 cytopathic effect is blocked with autophagy modulators

• Downloaded 3,334 times
• Download rankings, all-time:
  • Site-wide: 6,287
  • In pharmacology and toxicology: 38
• Year to date:
  • Site-wide: 28,318
• Since beginning of last month:
  • Site-wide: 30,316

Discovery of Synergistic and Antagonistic Drug Combinations against SARS-CoV-2 In Vitro

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• Download rankings, all-time:
  • Site-wide: 7,023
  • In microbiology: 441
• Year to date:
  • Site-wide: 29,790
• Since beginning of last month:
  • Site-wide: 103,023

Small Molecule Inhibitors of the Human Histone Lysine Methyltransferase NSD2 / WHSC1 / MMSET Identified from a Quantitative High-Throughput Screen with Nucleosome Substrate

• Downloaded 2,778 times
• Download rankings, all-time:
  • Site-wide: 8,179
  • In cancer biology: 129
• Year to date:
  • Site-wide: 91,701
• Since beginning of last month:
  • Site-wide: 33,019

An OpenData portal to share COVID-19 drug repurposing data in real time

• Downloaded 1,802 times
• Download rankings, all-time:
  • Site-wide: 15,797
  • In microbiology: 907
• Year to date:
  • Site-wide: 65,095
• Since beginning of last month:
  • Site-wide: 34,375

Identification of SARS-CoV-2 3CL Protease Inhibitors by a Quantitative High-throughput Screening

• Downloaded 1,592 times
• Download rankings, all-time:
  • Site-wide: 19,153
  • In pharmacology and toxicology: 115
• Year to date:
  • Site-wide: 122,459
• Since beginning of last month:
  • Site-wide: 54,217

Targeting ACE2-RBD interaction as a platform for COVID19 therapeutics: Development and drug repurposing screen of an AlphaLISA proximity assay

• Downloaded 1,522 times
• Download rankings, all-time:
  • Site-wide: 20,570
  • In biochemistry: 441
• Year to date:
  • Site-wide: 82,999
• Since beginning of last month:
  • Site-wide: 30,449

Identifying SARS-CoV-2 entry inhibitors through drug repurposing screens of SARS-S and MERS-S pseudotyped particles

• Downloaded 1,354 times
• Download rankings, all-time:
  • Site-wide: 24,863
  • In pharmacology and toxicology: 147
• Year to date:
  • Site-wide: 46,568
• Since beginning of last month:
  • Site-wide: 101,004

Drug Repurposing Screen for Compounds Inhibiting the Cytopathic Effect of SARS-CoV-2

• Downloaded 1,258 times
• Download rankings, all-time:
  • Site-wide: 27,925
  • In microbiology: 1,614
• Year to date:
  • Site-wide: 46,207
• Since beginning of last month:
  • Site-wide: 52,958

Discovery of TMPRSS2 inhibitors from virtual screening

• Downloaded 1,205 times
• Download rankings, all-time:
  • Site-wide: 29,838
  • In bioinformatics: 3,188
• Year to date:
  • Site-wide: 86,470
• Since beginning of last month:
  • Site-wide: 95,357

A Suite of TMPRSS2 Assays for Screening Drug Repurposing Candidates as Potential Treatments of COVID-19

• Downloaded 437 times
• Download rankings, all-time:
  • Site-wide: 119,776
  • In biochemistry: 3,518
• Year to date:
  • Site-wide: 99,333
• Since beginning of last month:
  • Site-wide: 194,448

Retro Drug Design: From Target Properties to Molecular Structures

• Downloaded 432 times
• Download rankings, all-time:
  • Site-wide: 121,039
  • In bioinformatics: 10,031
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 159,667

Quantitative bioactivity signatures of dietary supplements and natural products

• Downloaded 67 times
• Download rankings, all-time:
  • Site-wide: 213,509
  • In pharmacology and toxicology: 1,848
• Year to date:
  • Site-wide: 129,793
• Since beginning of last month:
  • Site-wide: 107,932