Author: Jin Wang

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Preprints

Beyond the circuit architecture: attractor dynamics reveals the mechanism of improved performance in decision-making and working memory

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Elemental diet enriched in amino acids alters gut microbial community and prevents colonic mucus degradation in mice with colitis

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CRISPR-Cas12b-assisted nucleic acid detection platform

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Enhancing Intracellular Accumulation and Target Engagement of PROTACs with Reversible Covalent Chemistry

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Room-temperature-storable PCR Mixes for SARS-CoV-2 Detection

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Transmission and clinical characteristics of coronavirus disease 2019 in 104 outside-Wuhan patients, China

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Tertiary Lymphoid Structure and CD8 T Cell Exclusion in Minimally Invasive Adenocarcinoma

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Lysosome Lipid Signaling from the Periphery to Neurons Regulates Longevity

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Quantifying the RNA cap epitranscriptome reveals novel caps in cellular and viral RNA

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TISCH: a comprehensive web resource enabling interactive single-cell transcriptome visualization of tumor microenvironment

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Conformational state switching and pathways of chromosome dynamics in cell cycle

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A CRISPR-Cas12a-based specific enhancer for more sensitive detection of SARS-CoV-2 infection

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Systematic Chromosome Rearrangement Induced by CRISPR-Cas9 Reshapes the Genome and Transcriptome of Human Cells

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  • In genomics: 4,623
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Quantitative Real-Time Imaging of Glutathione with Sub-Cellular Resolution

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  • In cell biology: 2,832
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New Cell Fate Potentials and Switching Kinetics Uncovered in a Classic Bistable Genetic Switch

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  • In biophysics: 2,177
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Changes in the Physicochemical Properties and Microbial Communities of Rhizospheric Soil after Cassava/Peanut Intercropping

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Cryo-EM structure of the MgtE Mg2+ channel pore domain in Mg2+-free conditions reveals cytoplasmic pore opening

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SELINA: Single-cell Assignment using Multiple-Adversarial Domain Adaptation Network with Large-scale References

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In vitro pancreatic islet cluster expansion facilitated by hormones and chemicals

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  • In cell biology: 4,495
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miR-200c Suppresses Stemness And Increases Cellular Sensitivity To Trastuzumab In HER2+ Breast Cancer

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  • In cancer biology: 2,990
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Disease Spectrum of Breast Cancer Susceptibility Genes

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  • In genetic and genomic medicine: 626
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Deciphering the molecular mechanism of the cancer formation by chromosome structural dynamics

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  • Site-wide: 114,111
  • In biophysics: 4,664
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Data-driven discovery of targets for bipotent anticancer drugs identifies Estrogen Related Receptor Alpha

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Megakaryocyte derived immune-stimulating cells regulate host-defense immunity against bacterial pathogens

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The wide distribution and horizontal transfers of beta satellite DNA in eukaryotes

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  • In evolutionary biology: 5,445
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The C-terminal non-catalytic domain of Mkp-1 phosphatase harbors a complex signal for rapid proteasome degradation in enterocytes

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  • Site-wide: 132,459
  • In immunology: 3,749
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Therapeutic inhibition of keratinocyte TRPV3 sensory channel by local anesthetic dyclonine

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  • Site-wide: 150,711
  • In biochemistry: 4,428
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Effects of artificially introduced Enterococcus faecalis strains in experimental necrotizing enterocolitis

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  • Site-wide: 151,676
  • In microbiology: 10,306
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Structural insights into the ion selectivity of the MgtE channel for Mg2+ over Ca2+

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  • In biophysics: 5,688
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Stochastic Epigenetic Dynamics of Gene Switching

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  • In biophysics: 5,777
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Reversible regulation of Cas12a activities by AcrVA5-mediated acetylation and CobB-mediated deacetylation

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  • In molecular biology: 4,821
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Investigations of the Underlying Mechanisms of HIF-1α and CITED2 Binding to TAZ1

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  • Site-wide: 167,313
  • In biophysics: 5,982
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Microscopic Chromosomal Structural and Dynamical Origin of Cell Differentiation and Reprogramming

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  • In biophysics: 6,018
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IKBIP is a novel EMT-related biomarker and predicts poor survival in glioma

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  • Site-wide: 171,974
  • In cancer biology: 4,973
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Calumenin contributes to epithelial-mesenchymal transition and predicts poor survival in glioma

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Acid-Base Homeostasis and Implications to the Phenotypic Behaviors of Cancer

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The trifecta of disease avoidance, silique shattering resistance and flowering period elongation achieved by the BnaIDA editing in Brassica napus

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Transcriptome profile and clinical characterization of ICOS expression in brain gliomas

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The Gene Knockout of Angiotensin II Type 1a Receptor Improves High-fat Diet-Induced Obesity in rat via Promoting Adipose Lipolysis

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  • Site-wide: 189,674
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Comprehensive RNA-Seq Reveals Molecular Changes in Kidney Malignancy Among People Living with HIV

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  • Site-wide: 189,824
  • In cancer biology: 5,437
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