Author: Yi Liu

Downloads per author, site-wide

Preprints

Unbalanced dietary patterns contribute to the pathogenesis of precocious puberty by affecting gut microbiota and host metabolites

No download data for this paper yet.

Complete genome characterisation of a novel coronavirus associated with severe human respiratory disease in Wuhan, China

• Downloaded 13,756 times
• Download rankings, all-time:
  • Site-wide: 505
  • In pathology: 4
• Year to date:
  • Site-wide: 1,956
• Since beginning of last month:
  • Site-wide: 2,894

Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases

• Downloaded 3,819 times
• Download rankings, all-time:
  • Site-wide: 2,904
  • In genetics: 113
• Year to date:
  • Site-wide: 9,343
• Since beginning of last month:
  • Site-wide: 9,317

Ultra-fast and onsite interrogation of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in environmental specimens via surface enhanced Raman scattering (SERS)

• Downloaded 3,679 times
• Download rankings, all-time:
  • Site-wide: 3,062
  • In infectious diseases: 595
• Year to date:
  • Site-wide: 1,871
• Since beginning of last month:
  • Site-wide: 2,289

Direct preparation of Cas9 ribonucleoprotein from E. coli for PCR-free seamless DNA assembly

• Downloaded 3,167 times
• Download rankings, all-time:
  • Site-wide: 3,806
  • In synthetic biology: 36
• Year to date:
  • Site-wide: 13,590
• Since beginning of last month:
  • Site-wide: 13,032

Mitochondrial dysfunction is signaled to the integrated stress response by OMA1, DELE1 and HRI

• Downloaded 1,958 times
• Download rankings, all-time:
  • Site-wide: 7,641
  • In cell biology: 174
• Year to date:
  • Site-wide: 36,014
• Since beginning of last month:
  • Site-wide: 63,797

Direct purification of CRISPR/Cas ribonucleoprotein from E. coli in a single step

• Downloaded 1,639 times
• Download rankings, all-time:
  • Site-wide: 9,985
  • In synthetic biology: 106
• Year to date:
  • Site-wide: 17,272
• Since beginning of last month:
  • Site-wide: 13,881

Fully Interpretable Deep Learning Model of Transcriptional Control

• Downloaded 1,347 times
• Download rankings, all-time:
  • Site-wide: 13,381
  • In systems biology: 264
• Year to date:
  • Site-wide: 89,418
• Since beginning of last month:
  • Site-wide: 77,688

Systematic quantification of health parameters from UK Biobank abdominal MRI using deep learning

• Downloaded 1,335 times
• Download rankings, all-time:
  • Site-wide: 13,546
  • In genetics: 664
• Year to date:
  • Site-wide: 5,443
• Since beginning of last month:
  • Site-wide: 8,704

Potential spreading risks and disinfection challenges of medical wastewater by the presence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) viral RNA in septic tanks of fangcang hospital

• Downloaded 1,237 times
• Download rankings, all-time:
  • Site-wide: 15,227
  • In public and global health: 297
• Year to date:
  • Site-wide: 20,137
• Since beginning of last month:
  • Site-wide: 21,658

Distributions and risks of SARS-CoV-2 in hospital outdoor environment

• Downloaded 1,206 times
• Download rankings, all-time:
  • Site-wide: 15,813
  • In infectious diseases: 1,507
• Year to date:
  • Site-wide: 10,672
• Since beginning of last month:
  • Site-wide: 7,725

Multi-omics study revealing tissue-dependent putative mechanisms of SARS-CoV-2 drug targets on viral infections and complex diseases

• Downloaded 1,191 times
• Download rankings, all-time:
  • Site-wide: 16,109
  • In genetic and genomic medicine: 55
• Year to date:
  • Site-wide: 29,632
• Since beginning of last month:
  • Site-wide: 25,808

Pleotropic effects of PPARD accelerate colorectal tumor progression and invasion

• Downloaded 994 times
• Download rankings, all-time:
  • Site-wide: 20,984
  • In cancer biology: 506
• Year to date:
  • Site-wide: 31,405
• Since beginning of last month:
  • Site-wide: 34,697

The MRC IEU OpenGWAS data infrastructure

• Downloaded 530 times
• Download rankings, all-time:
  • Site-wide: 48,969
  • In genetics: 2,288
• Year to date:
  • Site-wide: 11,612
• Since beginning of last month:
  • Site-wide: 16,072

A NOVEL MECHANISM FOR NF-κB-ACTIVATION VIA IκB-AGGREGATION: IMPLICATIONS FOR HEPATIC MALLORY-DENK-BODY INDUCED INFLAMMATION

• Downloaded 514 times
• Download rankings, all-time:
  • Site-wide: 50,692
  • In cell biology: 2,193
• Year to date:
  • Site-wide: 43,381
• Since beginning of last month:
  • Site-wide: 52,465

H+- and Na+- elicited swift changes of the microtubule system in the biflagellated green alga Chlamydomonas

• Downloaded 393 times
• Download rankings, all-time:
  • Site-wide: 67,482
  • In cell biology: 3,054
• Year to date:
  • Site-wide: 104,892
• Since beginning of last month:
  • Site-wide: 96,399

Suppression of membranous LRP5 recycling, WNT/β-catenin signaling, and colorectal tumorigenesis by 15-LOX-1 peroxidation of PI3P_linoleic acid

• Downloaded 366 times
• Download rankings, all-time:
  • Site-wide: 72,117
  • In cancer biology: 2,106
• Year to date:
  • Site-wide: 63,135
• Since beginning of last month:
  • Site-wide: 57,236

Assessment of the aging of the brown adipose tissue by 18F-FDG PET/CT imaging in the progeria mouse model LmnaG609G/G609G

• Downloaded 359 times
• Download rankings, all-time:
  • Site-wide: 73,182
  • In cell biology: 3,336
• Year to date:
  • Site-wide: 128,920
• Since beginning of last month:
  • Site-wide: 132,414

Robust bidirectional communication between electronics and an engineered multi-functional microbial community

• Downloaded 339 times
• Download rankings, all-time:
  • Site-wide: 76,842
  • In synthetic biology: 849
• Year to date:
  • Site-wide: 43,515
• Since beginning of last month:
  • Site-wide: 50,323

Electron transport chain biogenesis activated by a JNK-insulin-Myc relay primes mitochondrial inheritance in Drosophila

• Downloaded 315 times
• Download rankings, all-time:
  • Site-wide: 81,605
  • In developmental biology: 2,178
• Year to date:
  • Site-wide: 118,311
• Since beginning of last month:
  • Site-wide: 105,722

Identification and physiological significance of temporal NFκB signaling codewords deployed by macrophages to classify immune threats

• Downloaded 311 times
• Download rankings, all-time:
  • Site-wide: 82,345
  • In immunology: 2,291
• Year to date:
  • Site-wide: 40,738
• Since beginning of last month:
  • Site-wide: 55,385

Induction via Functional Protein Stabilization of Hepatic Cytochromes P450 upon gp78/ Autocrine Motility Factor Receptor (AMFR) Ubiquitin E3-ligase Genetic Ablation in Mice: Therapeutic and Toxicological Relevance.

• Downloaded 296 times
• Download rankings, all-time:
  • Site-wide: 85,441
  • In pharmacology and toxicology: 581
• Year to date:
  • Site-wide: 106,425
• Since beginning of last month:
  • Site-wide: 81,359

Shared B cell memory to coronaviruses and other pathogens varies in human age groups and tissues

• Downloaded 271 times
• Download rankings, all-time:
  • Site-wide: 90,742
  • In immunology: 2,555
• Year to date:
  • Site-wide: 32,928
• Since beginning of last month:
  • Site-wide: 56,317

Modulation of the cAMP levels with a conserved actinobacteria phosphodiesterase enzyme reduces antimicrobial tolerance in mycobacteria

• Downloaded 257 times
• Download rankings, all-time:
  • Site-wide: 94,011
  • In microbiology: 6,791
• Year to date:
  • Site-wide: 40,890
• Since beginning of last month:
  • Site-wide: 43,046

EpiGraphDB: a database and data mining platform for health data science

• Downloaded 236 times
• Download rankings, all-time:
  • Site-wide: 98,539
  • In bioinformatics: 8,486
• Year to date:
  • Site-wide: 98,817
• Since beginning of last month:
  • Site-wide: 109,464

Development of rice conidiation media for Ustilaginoidea virens

• Downloaded 233 times
• Download rankings, all-time:
  • Site-wide: 99,177
  • In microbiology: 7,229
• Year to date:
  • Site-wide: 127,571
• Since beginning of last month:
  • Site-wide: 124,927

Clinical Course And Risk Factors For In-hospital Death In Critical COVID-19 In Wuhan, China

• Downloaded 226 times
• Download rankings, all-time:
  • Site-wide: 100,585
  • In public and global health: 1,113
• Year to date:
  • Site-wide: 37,599
• Since beginning of last month:
  • Site-wide: 38,706

Effects of Diabetes and Blood Glucose on COVID-19 Mortality: A Retrospective Observational Study

• Downloaded 220 times
• Download rankings, all-time:
  • Site-wide: 101,971
  • In public and global health: 1,130
• Year to date:
  • Site-wide: 8,874
• Since beginning of last month:
  • Site-wide: 24,020

PPARD regulation in gastric progenitor cells drives gastric tumorigenesis in mice

• Downloaded 200 times
• Download rankings, all-time:
  • Site-wide: 106,457
  • In cancer biology: 3,252
• Year to date:
  • Site-wide: 132,451
• Since beginning of last month:
  • Site-wide: 123,571

Human hepatic tryptophan 2,3-dioxygenase ubiquitin-dependent protein degradation: The critical role of its exosite as the molecular lynchpin of its substrate-mediated protein stabilization

• Downloaded 198 times
• Download rankings, all-time:
  • Site-wide: 106,955
  • In biochemistry: 3,131
• Year to date:
  • Site-wide: 107,728
• Since beginning of last month:
  • Site-wide: 92,528

Ppard is Essential in Acceleration of Pancreatic Ductal Adenocarcinoma Development by High-Fat Diet in Mutant Kras Mice

• Downloaded 150 times
• Download rankings, all-time:
  • Site-wide: 117,252
  • In cancer biology: 3,611
• Year to date:
  • Site-wide: 58,389
• Since beginning of last month:
  • Site-wide: 76,645

Reengineering the Specificity of the Highly Selective Clostridium botulinum Protease via Directed Evolution

• Downloaded 138 times
• Download rankings, all-time:
  • Site-wide: 119,453
  • In biochemistry: 3,575
• Year to date:
  • Site-wide: 61,008
• Since beginning of last month:
  • Site-wide: 109,692

Requirement and functional redundancy of two large ribonucleotide reductase subunit genes for cell cycle, chloroplast biogenesis in tomato

• Downloaded 133 times
• Download rankings, all-time:
  • Site-wide: 120,496
  • In developmental biology: 3,222
• Year to date:
  • Site-wide: 114,117
• Since beginning of last month:
  • Site-wide: 66,925

Phagocytosis by stroma confounds co-culture studies

• Downloaded 128 times
• Download rankings, all-time:
  • Site-wide: 121,423
  • In cancer biology: 3,778
• Year to date:
  • Site-wide: 69,335
• Since beginning of last month:
  • Site-wide: 44,511

Methylomic alteration in peripheral blood lymphocytes of prodromal stage and first-episode Chinese Han schizophrenia patients

• Downloaded 110 times
• Download rankings, all-time:
  • Site-wide: 124,745
  • In genetics: 5,264
• Year to date:
  • Site-wide: 21,501
• Since beginning of last month:
  • Site-wide: 26,136

Deficiency of gluconeogenic enzyme PCK1 promotes non-alcoholic steatohepatitis progression by activation of PI3K/AKT/PDGF axis

• Downloaded 103 times
• Download rankings, all-time:
  • Site-wide: 126,014
  • In molecular biology: 3,784
• Year to date:
  • Site-wide: 23,423
• Since beginning of last month:
  • Site-wide: 56,469

Non-optimal codon usage is critical for protein structure and function of the master general amino acid control regulator CPC-1

• Downloaded 99 times
• Download rankings, all-time:
  • Site-wide: 126,678
  • In molecular biology: 3,813
• Year to date:
  • Site-wide: 131,689
• Since beginning of last month:
  • Site-wide: 131,205

Is there a need for preoperative α-blocker in patients missed preoperative diagnosis of extra-adrenal retroperitoneal paraganglioma undergoing paraganglioma resection? A retrospective study of 167 cases at a single center

• Downloaded 97 times
• Download rankings, all-time:
  • Site-wide: 127,006
  • In physiology: 1,529
• Year to date:
  • Site-wide: 122,379
• Since beginning of last month:
  • Site-wide: 109,728