Author: Tim B. Bigdeli

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Preprints

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

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  • Site-wide: 1,393
  • In genetics: 27
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  • Site-wide: 21,548

Exome sequencing identifies rare coding variants in 10 genes which confer substantial risk for schizophrenia

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  • Site-wide: 1,510
  • In genetic and genomic medicine: 8
• Year to date:
  • Site-wide: 1,998
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  • Site-wide: 1,197

Genome-wide association study of over 40,000 bipolar disorder cases provides new insights into the underlying biology

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  • Site-wide: 5,348
  • In psychiatry and clinical psychology: 20
• Year to date:
  • Site-wide: 9,333
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  • Site-wide: 18,379

Trans-ancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

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  • Site-wide: 12,615
  • In genetics: 466
• Year to date:
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  • Site-wide: 141,476

A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

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  • Site-wide: 13,665
  • In genetics: 525
• Year to date:
  • Site-wide: 41,150
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  • Site-wide: 198,181

Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

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  • Site-wide: 18,558
  • In genomics: 1,676
• Year to date:
  • Site-wide: 112,578
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  • Site-wide: 51,987

Shared Genetic Risk between Eating Disorder- and Substance-Use-Related Phenotypes: Evidence from Genome-Wide Association Studies

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  • Site-wide: 31,482
  • In genetics: 1,278
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Genome-wide association study identifies new locus associated with OCD

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  • Site-wide: 34,613
  • In psychiatry and clinical psychology: 149
• Year to date:
  • Site-wide: 12,720
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  • Site-wide: 10,804

Leveraging genome-wide data to investigate differences between opioid use vs. opioid dependence in 41,176 individuals from the Psychiatric Genomics Consortium

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  • Site-wide: 36,477
  • In genetics: 1,443
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  • Site-wide: 97,443
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  • Site-wide: 184,095

Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores

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  • Site-wide: 41,248
  • In genetics: 1,628
• Year to date:
  • Site-wide: 135,961
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  • Site-wide: 201,487

Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders and known risk factors

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  • Site-wide: 44,052
  • In genetic and genomic medicine: 273
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  • Site-wide: 83,879
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  • Site-wide: 112,490

Genome-wide Association Study of Clinical Features in the Schizophrenia Psychiatric Genomics Consortium: Confirmation of Polygenic Effect on Negative Symptoms

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  • Site-wide: 47,589
  • In genetics: 1,866
• Year to date:
  • Site-wide: 93,611
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  • Site-wide: 74,916

Characterization of Age and Polarity at Onset in Bipolar Disorder

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  • Site-wide: 86,064
  • In psychiatry and clinical psychology: 418
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  • Site-wide: 145,071
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  • Site-wide: 56,559

FIQT: a simple, powerful method to accurately estimate effect sizes in genome scans

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  • Site-wide: 90,564
  • In genetics: 3,456
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  • Site-wide: 175,348

Investigation of convergent and divergent genetic influences underlying schizophrenia and alcohol use disorder

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  • Site-wide: 91,665
  • In genetic and genomic medicine: 590
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  • Site-wide: 125,967
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  • Site-wide: 85,961

History of suicide attempts and COVID-19 infection in Veterans with schizophrenia or schizoaffective disorder: effect modification by age and obesity

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  • Site-wide: 95,033
  • In psychiatry and clinical psychology: 476
• Year to date:
  • Site-wide: 107,762
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  • Site-wide: 72,498

Polygenic risk scores lack prognostic value for adults with severe mental illness

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  • Site-wide: 104,101
  • In genetic and genomic medicine: 676
• Year to date:
  • Site-wide: 100,361
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  • Site-wide: 82,838

Distinctive cross-ancestry genetic architecture for age-related macular degeneration

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  • Site-wide: 153,522
  • In genetic and genomic medicine: 1,152
• Year to date:
  • Site-wide: 7,306
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Penetrance and Pleiotropy of Polygenic Risk Scores for Schizophrenia, Bipolar Disorder, and Depression in the VA Health Care System

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  • Site-wide: 155,704
  • In genetic and genomic medicine: 1,120
• Year to date:
  • Site-wide: 42,843
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  • Site-wide: 104,786