Author: Ian G. Goodfellow

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Preprints

Improvements to the ARTIC multiplex PCR method for SARS-CoV-2 genome sequencing using nanopore

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  • Site-wide: 4,518
  • In genomics: 504
• Year to date:
  • Site-wide: 806
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  • Site-wide: 1,338

Delayed bystander CD8 T cell activation, early immune pathology and persistent dysregulation characterise severe COVID-19

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  • Site-wide: 4,961
  • In infectious diseases: 819
• Year to date:
  • Site-wide: 366
• Since beginning of last month:
  • Site-wide: 1,058

Rapid implementation of real-time SARS-CoV-2 sequencing to investigate healthcare-associated COVID-19 infections

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  • Site-wide: 5,162
  • In infectious diseases: 841
• Year to date:
  • Site-wide: 13,672
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  • Site-wide: 15,797

Virus genomes reveal the factors that spread and sustained the West African Ebola epidemic.

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  • Site-wide: 5,667
  • In epidemiology: 482
• Year to date:
  • Site-wide: 62,367
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  • Site-wide: 98,017

Combined point of care nucleic acid and antibody testing for SARS-CoV-2: a prospective cohort study in suspected moderate to severe COVID-19 disease.

• Downloaded 2,035 times
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  • Site-wide: 7,340
  • In infectious diseases: 1,018
• Year to date:
  • Site-wide: 20,746
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  • Site-wide: 37,491

A blueprint for the implementation of a validated approach for the detection of SARS-Cov2 in clinical samples in academic facilities

• Downloaded 1,953 times
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  • Site-wide: 7,816
  • In molecular biology: 189
• Year to date:
  • Site-wide: 23,097
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  • Site-wide: 20,780

A thermostable, closed, SARS-CoV-2 spike protein trimer.

• Downloaded 1,902 times
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  • Site-wide: 8,134
  • In biochemistry: 157
• Year to date:
  • Site-wide: 13,809
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  • Site-wide: 14,025

The short- and long-range RNA-RNA Interactome of SARS-CoV-2

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  • Site-wide: 10,852
  • In molecular biology: 296
• Year to date:
  • Site-wide: 36,911
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  • Site-wide: 37,379

The translational landscape of Zika virus during infection of mammalian and insect cells

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  • Site-wide: 18,633
  • In microbiology: 1,052
• Year to date:
  • Site-wide: 75,023
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  • Site-wide: 86,047

Calicivirus VP2 forms a portal to mediate endosome escape

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  • Site-wide: 19,095
  • In microbiology: 1,075
• Year to date:
  • Site-wide: 49,063
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  • Site-wide: 55,520

Screening of healthcare workers for SARS-CoV-2 highlights the role of asymptomatic carriage in COVID-19 transmission

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  • Site-wide: 21,829
  • In infectious diseases: 1,759
• Year to date:
  • Site-wide: 50,911
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  • Site-wide: 51,200

A robust human norovirus replication model in zebrafish larvae

• Downloaded 934 times
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  • Site-wide: 23,351
  • In microbiology: 1,339
• Year to date:
  • Site-wide: 125,933
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  • Site-wide: 117,981

Norovirus replication in human intestinal epithelial cells is restricted by the interferon-induced JAK/STAT signalling pathway and RNA Polymerase II mediated transcriptional responses.

• Downloaded 754 times
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  • Site-wide: 31,589
  • In microbiology: 1,870
• Year to date:
  • Site-wide: 104,034
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  • Site-wide: 101,546

Noroviruses subvert the core stress granule component G3BP1 to promote viral VPg-dependent translation.

• Downloaded 745 times
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  • Site-wide: 32,137
  • In microbiology: 1,905
• Year to date:
  • Site-wide: 103,810
• Since beginning of last month:
  • Site-wide: 73,478

A2B-COVID: A method for evaluating potential SARS-CoV-2 transmission events

• Downloaded 663 times
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  • Site-wide: 37,554
  • In epidemiology: 1,826
• Year to date:
  • Site-wide: 13,602
• Since beginning of last month:
  • Site-wide: 25,057

Norovirus-mediated modification of the translational landscape via virus and host-induced cleavage of translation initiation factors.

• Downloaded 655 times
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  • Site-wide: 38,174
  • In microbiology: 2,290
• Year to date:
  • Site-wide: 100,479
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  • Site-wide: 112,010

Epigenetic suppression of interferon lambda receptor expression leads to enhanced HuNoV replication in vitro

• Downloaded 588 times
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  • Site-wide: 43,783
  • In microbiology: 2,709
• Year to date:
  • Site-wide: 111,019
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  • Site-wide: 117,840

A prospective study of risk factors associated with seroprevalence of SARS-CoV-2 antibodies in healthcare workers at a large UK teaching hospital

• Downloaded 399 times
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  • Site-wide: 67,524
  • In infectious diseases: 3,079
• Year to date:
  • Site-wide: 34,509
• Since beginning of last month:
  • Site-wide: 27,846

Central carbon metabolism is an intrinsic factor for optimal replication of a norovirus

• Downloaded 386 times
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  • Site-wide: 69,501
  • In microbiology: 4,706
• Year to date:
  • Site-wide: 80,296
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  • Site-wide: 102,593

Spatial and temporal control of norovirus protease activity is determined by polyprotein processing and intermolecular interactions within the viral replication complex.

• Downloaded 335 times
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  • Site-wide: 78,793
  • In microbiology: 5,452
• Year to date:
  • Site-wide: 103,391
• Since beginning of last month:
  • Site-wide: 122,983

Murine norovirus virulence factor 1 (VF1) protein contributes to viral fitness during persistent infection

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  • Site-wide: 96,165
  • In microbiology: 6,937
• Year to date:
  • Site-wide: 103,908
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  • Site-wide: 115,993

The cryo-EM structure of vesivirus 2117 highlights functional variations in entry pathways for viruses in different clades of the vesivirus genus.

• Downloaded 156 times
• Download rankings, all-time:
  • Site-wide: 117,476
  • In microbiology: 8,842
• Year to date:
  • Site-wide: 16,572
• Since beginning of last month:
  • Site-wide: 15,215