Rxivist logo

Author: Ralph S Baric

Rankings

  • All-time downloads: 353,919 (rank: 112 )
  • Categories:
    • allergy and immunology: 729 (rank: 1,957 (tie) )
    • biochemistry: 8,420 (rank: 348 (tie) )
    • cell biology: 5,677 (rank: 960 )
    • epidemiology: 480 (rank: 22,795 (tie) )
    • evolutionary biology: 390 (rank: 20,766 (tie) )
    • genetics: 979 (rank: 19,049 (tie) )
    • immunology: 71,631 (rank: 195 )
    • infectious diseases: 53,047 (rank: 1,351 )
    • microbiology: 196,907 (rank: 63 )
    • pharmacology and toxicology: 766 (rank: 2,500 (tie) )

Downloads per author, site-wide

Preprints

A Multitrait Locus Regulates Sarbecovirus Pathogenesis

microbiology more details view paper

No download data for this paper yet.

Severe acute respiratory syndrome-related coronavirus – The species and its viruses, a statement of the Coronavirus Study Group

microbiology more details view paper
  • Downloaded 124,773 times
  • Download rankings, all-time:
    • Site-wide: 49
    • In microbiology: 3
  • Year to date:
    • Site-wide: 201
  • Since beginning of last month:
    • Site-wide: 244

SARS-CoV-2 mRNA Vaccine Development Enabled by Prototype Pathogen Preparedness

immunology more details view paper
  • Downloaded 37,218 times
  • Download rankings, all-time:
    • Site-wide: 263
    • In immunology: 12
  • Year to date:
    • Site-wide: 1,113
  • Since beginning of last month:
    • Site-wide: 1,652

Molnupiravir, an Oral Antiviral Treatment for COVID-19

infectious diseases more details view paper
  • Downloaded 31,067 times
  • Download rankings, all-time:
    • Site-wide: 320
    • In infectious diseases: 127
  • Year to date:
    • Site-wide: 224
  • Since beginning of last month:
    • Site-wide: 376

An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 and multiple endemic, epidemic and bat coronavirus

microbiology more details view paper
  • Downloaded 20,142 times
  • Download rankings, all-time:
    • Site-wide: 539
    • In microbiology: 53
  • Year to date:
    • Site-wide: 18,440
  • Since beginning of last month:
    • Site-wide: 24,343

Homologous and Heterologous Vaccine Boost Strategies for Humoral and Cellular Immunologic Coverage of the SARS-CoV-2 Omicron Variant

infectious diseases more details view paper
  • Downloaded 18,839 times
  • Download rankings, all-time:
    • Site-wide: 572
    • In infectious diseases: 220
  • Year to date:
    • Site-wide: 280
  • Since beginning of last month:
    • Site-wide: 2,052

A mouse-adapted SARS-CoV-2 model for the evaluation of COVID-19 medical countermeasures

microbiology more details view paper
  • Downloaded 9,809 times
  • Download rankings, all-time:
    • Site-wide: 1,309
    • In microbiology: 117
  • Year to date:
    • Site-wide: 17,801
  • Since beginning of last month:
    • Site-wide: 22,473

LY-CoV555, a rapidly isolated potent neutralizing antibody, provides protection in a non-human primate model of SARS-CoV-2 infection

immunology more details view paper
  • Downloaded 8,315 times
  • Download rankings, all-time:
    • Site-wide: 1,605
    • In immunology: 56
  • Year to date:
    • Site-wide: 4,471
  • Since beginning of last month:
    • Site-wide: 4,037

Progenitor identification and SARS-CoV-2 infection in long-term human distal lung organoid cultures

cell biology more details view paper
  • Downloaded 5,422 times
  • Download rankings, all-time:
    • Site-wide: 2,842
    • In cell biology: 42
  • Year to date:
    • Site-wide: 9,860
  • Since beginning of last month:
    • Site-wide: 7,496

Remdesivir potently inhibits SARS-CoV-2 in human lung cells and chimeric SARS-CoV expressing the SARS-CoV-2 RNA polymerase in mice.

microbiology more details view paper
  • Downloaded 5,404 times
  • Download rankings, all-time:
    • Site-wide: 2,851
    • In microbiology: 213
  • Year to date:
    • Site-wide: 29,841
  • Since beginning of last month:
    • Site-wide: 43,893

Newcastle disease virus (NDV) expressing the spike protein of SARS-CoV-2 as vaccine candidate

microbiology more details view paper
  • Downloaded 5,091 times
  • Download rankings, all-time:
    • Site-wide: 3,112
    • In microbiology: 224
  • Year to date:
    • Site-wide: 32,365
  • Since beginning of last month:
    • Site-wide: 27,123

Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein

immunology more details view paper
  • Downloaded 5,055 times
  • Download rankings, all-time:
    • Site-wide: 3,122
    • In immunology: 120
  • Year to date:
    • Site-wide: 43,221
  • Since beginning of last month:
    • Site-wide: 41,457

Specific viral RNA drives the SARS CoV-2 nucleocapsid to phase separate

biochemistry more details view paper
  • Downloaded 4,715 times
  • Download rankings, all-time:
    • Site-wide: 3,422
    • In biochemistry: 53
  • Year to date:
    • Site-wide: 18,433
  • Since beginning of last month:
    • Site-wide: 14,729

SARS-CoV-2 D614G Variant Exhibits Enhanced Replication ex vivo and Earlier Transmission in vivo

microbiology more details view paper
  • Downloaded 4,301 times
  • Download rankings, all-time:
    • Site-wide: 3,866
    • In microbiology: 262
  • Year to date:
    • Site-wide: 33,266
  • Since beginning of last month:
    • Site-wide: 28,375

Potently neutralizing human antibodies that block SARS-CoV-2 receptor binding and protect animals

immunology more details view paper
  • Downloaded 4,300 times
  • Download rankings, all-time:
    • Site-wide: 3,867
    • In immunology: 150
  • Year to date:
    • Site-wide: 22,423
  • Since beginning of last month:
    • Site-wide: 25,027

Elicitation of potent neutralizing antibody responses by designed protein nanoparticle vaccines for SARS-CoV-2

immunology more details view paper
  • Downloaded 4,074 times
  • Download rankings, all-time:
    • Site-wide: 4,188
    • In immunology: 156
  • Year to date:
    • Site-wide: 52,647
  • Since beginning of last month:
    • Site-wide: 54,205

Cryo-electron Microscopy and Exploratory Antisense Targeting of the 28-kDa Frameshift Stimulation Element from the SARS-CoV-2 RNA Genome

biochemistry more details view paper
  • Downloaded 3,982 times
  • Download rankings, all-time:
    • Site-wide: 4,326
    • In biochemistry: 64
  • Year to date:
    • Site-wide: 11,581
  • Since beginning of last month:
    • Site-wide: 12,855

Rapid selection of a human monoclonal antibody that potently neutralizes SARS-CoV-2 in two animal models

microbiology more details view paper
  • Downloaded 3,543 times
  • Download rankings, all-time:
    • Site-wide: 5,104
    • In microbiology: 332
  • Year to date:
    • Site-wide: 38,854
  • Since beginning of last month:
    • Site-wide: 34,788

Chimeric spike mRNA vaccines protect against Sarbecovirus challenge in mice

microbiology more details view paper
  • Downloaded 3,413 times
  • Download rankings, all-time:
    • Site-wide: 5,408
    • In microbiology: 359
  • Year to date:
    • Site-wide: 14,436
  • Since beginning of last month:
    • Site-wide: 39,393

The RBD Of The Spike Protein Of SARS-Group Coronaviruses Is A Highly Specific Target Of SARS-CoV-2 Antibodies But Not Other Pathogenic Human and Animal Coronavirus Antibodies

infectious diseases more details view paper
  • Downloaded 3,151 times
  • Download rankings, all-time:
    • Site-wide: 6,057
    • In infectious diseases: 1,137
  • Year to date:
    • Site-wide: 28,345
  • Since beginning of last month:
    • Site-wide: 38,777

Therapeutic efficacy of an oral nucleoside analog of remdesivir against SARS-CoV-2 pathogenesis in mice.

microbiology more details view paper
  • Downloaded 2,720 times
  • Download rankings, all-time:
    • Site-wide: 7,506
    • In microbiology: 477
  • Year to date:
    • Site-wide: 6,141
  • Since beginning of last month:
    • Site-wide: 10,512

Broad sarbecovirus neutralizing antibodies define a key site of vulnerability on the SARS-CoV-2 spike protein

immunology more details view paper
  • Downloaded 2,648 times
  • Download rankings, all-time:
    • Site-wide: 7,819
    • In immunology: 278
  • Year to date:
    • Site-wide: 58,596
  • Since beginning of last month:
    • Site-wide: 84,604

Mucin 4 Protects Female Mice from Coronavirus Pathogenesis

microbiology more details view paper
  • Downloaded 2,478 times
  • Download rankings, all-time:
    • Site-wide: 8,620
    • In microbiology: 498
  • Year to date:
    • Site-wide: 54,413
  • Since beginning of last month:
    • Site-wide: 29,814

Combination attenuation offers strategy for live-attenuated coronavirus vaccines

microbiology more details view paper
  • Downloaded 2,429 times
  • Download rankings, all-time:
    • Site-wide: 8,880
    • In microbiology: 501
  • Year to date:
    • Site-wide: 106,923
  • Since beginning of last month:
    • Site-wide: 117,133

Evaluation of SARS-CoV-2 neutralization assays for antibody monitoring in natural infection and vaccine trials

infectious diseases more details view paper
  • Downloaded 2,265 times
  • Download rankings, all-time:
    • Site-wide: 9,833
    • In infectious diseases: 1,569
  • Year to date:
    • Site-wide: 11,857
  • Since beginning of last month:
    • Site-wide: 17,744

Trypsin treatment unlocks barrier for zoonotic coronaviruses infection

microbiology more details view paper
  • Downloaded 2,167 times
  • Download rankings, all-time:
    • Site-wide: 10,494
    • In microbiology: 593
  • Year to date:
    • Site-wide: 34,196
  • Since beginning of last month:
    • Site-wide: 48,759

An Engineered Antibody with Broad Protective Efficacy in Murine Models of SARS and COVID-19

immunology more details view paper
  • Downloaded 2,140 times
  • Download rankings, all-time:
    • Site-wide: 10,696
    • In immunology: 387
  • Year to date:
    • Site-wide: 24,174
  • Since beginning of last month:
    • Site-wide: 19,853

A Newcastle disease virus (NDV) expressing membrane-anchored spike as a cost-effective inactivated SARS-CoV-2 vaccine

microbiology more details view paper
  • Downloaded 2,111 times
  • Download rankings, all-time:
    • Site-wide: 10,940
    • In microbiology: 623
  • Year to date:
    • Site-wide: 59,290
  • Since beginning of last month:
    • Site-wide: 67,846

High-density amplicon sequencing identifies community spread and ongoing evolution of SARS-CoV-2 in the Southern United States

microbiology more details view paper
  • Downloaded 1,958 times
  • Download rankings, all-time:
    • Site-wide: 12,263
    • In microbiology: 697
  • Year to date:
    • Site-wide: 54,416
  • Since beginning of last month:
    • Site-wide: 33,470

A broadly neutralizing antibody protects against SARS-CoV, pre-emergent bat CoVs, and SARS-CoV-2 variants in mice

microbiology more details view paper
  • Downloaded 1,883 times
  • Download rankings, all-time:
    • Site-wide: 12,982
    • In microbiology: 802
  • Year to date:
    • Site-wide: 13,350
  • Since beginning of last month:
    • Site-wide: 12,958

Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes in COVID-19 convalescent plasma

immunology more details view paper
  • Downloaded 1,830 times
  • Download rankings, all-time:
    • Site-wide: 13,506
    • In immunology: 467
  • Year to date:
    • Site-wide: 33,526
  • Since beginning of last month:
    • Site-wide: 52,728

Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines

immunology more details view paper
  • Downloaded 1,820 times
  • Download rankings, all-time:
    • Site-wide: 13,615
    • In immunology: 500
  • Year to date:
    • Site-wide: 21,775
  • Since beginning of last month:
    • Site-wide: 44,299

Prevention and therapy of SARS-CoV-2 and the B.1.351 variant in mice

microbiology more details view paper
  • Downloaded 1,795 times
  • Download rankings, all-time:
    • Site-wide: 13,911
    • In microbiology: 772
  • Year to date:
    • Site-wide: 74,163
  • Since beginning of last month:
    • Site-wide: 65,114

Antibody potency, effector function and combinations in protection from SARS-CoV-2 infection in vivo

microbiology more details view paper
  • Downloaded 1,733 times
  • Download rankings, all-time:
    • Site-wide: 14,662
    • In microbiology: 820
  • Year to date:
    • Site-wide: 64,009
  • Since beginning of last month:
    • Site-wide: 57,254

Cross-reactive coronavirus antibodies with diverse epitope specificities and extra-neutralization functions

immunology more details view paper
  • Downloaded 1,619 times
  • Download rankings, all-time:
    • Site-wide: 16,207
    • In immunology: 584
  • Year to date:
    • Site-wide: 29,594
  • Since beginning of last month:
    • Site-wide: 47,694

Comparative analysis of coronavirus genomic RNA structure reveals conservation in SARS-like coronaviruses

microbiology more details view paper
  • Downloaded 1,475 times
  • Download rankings, all-time:
    • Site-wide: 18,734
    • In microbiology: 1,087
  • Year to date:
    • Site-wide: 37,714
  • Since beginning of last month:
    • Site-wide: 29,316

Breadth of SARS-CoV-2 Neutralization and Protection Induced by a Nanoparticle Vaccine

immunology more details view paper
  • Downloaded 1,204 times
  • Download rankings, all-time:
    • Site-wide: 25,719
    • In immunology: 1,497
  • Year to date:
    • Site-wide: 1,276
  • Since beginning of last month:
    • Site-wide: 6,368

SARS-CoV-2 mRNA Vaccine Induces Robust Specific and Cross-reactive IgG and Unequal Strain-specific Neutralizing Antibodies in Naïve and Previously Infected Recipients

immunology more details view paper
  • Downloaded 1,113 times
  • Download rankings, all-time:
    • Site-wide: 29,000
    • In immunology: 958
  • Year to date:
    • Site-wide: 72,812
  • Since beginning of last month:
    • Site-wide: 87,029

Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause severe disease

immunology more details view paper
  • Downloaded 1,106 times
  • Download rankings, all-time:
    • Site-wide: 29,254
    • In immunology: None
  • Year to date:
    • Site-wide: 1,442
  • Since beginning of last month:
    • Site-wide: 3,162

Targeted isolation of panels of diverse human protective broadly neutralizing antibodies against SARS-like viruses

immunology more details view paper
  • Downloaded 1,084 times
  • Download rankings, all-time:
    • Site-wide: 30,195
    • In immunology: 1,249
  • Year to date:
    • Site-wide: 4,859
  • Since beginning of last month:
    • Site-wide: 13,906

A model of persistent post SARS-CoV-2 induced lung disease for target identification and testing of therapeutic strategies

microbiology more details view paper
  • Downloaded 1,016 times
  • Download rankings, all-time:
    • Site-wide: 33,206
    • In microbiology: None
  • Year to date:
    • Site-wide: 1,647
  • Since beginning of last month:
    • Site-wide: 2,627

Common Mechanism of SARS-CoV and SARS-CoV-2 Pathogenesis across Species

microbiology more details view paper
  • Downloaded 1,012 times
  • Download rankings, all-time:
    • Site-wide: 33,429
    • In microbiology: 2,139
  • Year to date:
    • Site-wide: 28,251
  • Since beginning of last month:
    • Site-wide: 26,653

Sex disparities and neutralizing antibody durability to SARS-CoV-2 infection in convalescent individuals

allergy and immunology more details view paper
  • Downloaded 849 times
  • Download rankings, all-time:
    • Site-wide: 43,329
    • In allergy and immunology: 126
  • Year to date:
    • Site-wide: 27,490
  • Since beginning of last month:
    • Site-wide: 8,088

Infectious SARS-CoV-2 Virus in Symptomatic COVID-19 Outpatients: Host, Disease, and Viral Correlates

infectious diseases more details view paper
  • Downloaded 844 times
  • Download rankings, all-time:
    • Site-wide: 43,793
    • In infectious diseases: 3,456
  • Year to date:
    • Site-wide: 30,884
  • Since beginning of last month:
    • Site-wide: 40,787

MERS-CoV NSP16 necessary for IFN resistance and viral pathogenesis

microbiology more details view paper
  • Downloaded 816 times
  • Download rankings, all-time:
    • Site-wide: 45,941
    • In microbiology: 2,574
  • Year to date:
    • Site-wide: 121,126
  • Since beginning of last month:
    • Site-wide: 148,832

Repurposing the Ebola and Marburg Virus Inhibitors Tilorone, Quinacrine and Pyronaridine: In vitro Activity Against SARS-CoV-2 and Potential Mechanisms

pharmacology and toxicology more details view paper
  • Downloaded 804 times
  • Download rankings, all-time:
    • Site-wide: 46,935
    • In pharmacology and toxicology: 270
  • Year to date:
    • Site-wide: 75,546
  • Since beginning of last month:
    • Site-wide: 64,139

Baseline T cell immune phenotypes predict virologic and disease control upon SARS-CoV infection

immunology more details view paper
  • Downloaded 763 times
  • Download rankings, all-time:
    • Site-wide: 50,697
    • In immunology: 1,541
  • Year to date:
    • Site-wide: 131,987
  • Since beginning of last month:
    • Site-wide: 119,732

Distinct genetic determinants and mechanisms of SARS-CoV-2 resistance to remdesivir

microbiology more details view paper
  • Downloaded 726 times
  • Download rankings, all-time:
    • Site-wide: 54,352
    • In microbiology: 4,873
  • Year to date:
    • Site-wide: 2,814
  • Since beginning of last month:
    • Site-wide: 22,364

Protective efficacy of rhesus adenovirus COVID-19 vaccines against mouse-adapted SARS-CoV-2

microbiology more details view paper
  • Downloaded 641 times
  • Download rankings, all-time:
    • Site-wide: 64,574
    • In microbiology: 4,382
  • Year to date:
    • Site-wide: 44,162
  • Since beginning of last month:
    • Site-wide: 32,830

Host kinase CSNK2 is a target for inhibition of pathogenic β-coronaviruses including SARS-CoV-2

cell biology more details view paper
  • Downloaded 609 times
  • Download rankings, all-time:
    • Site-wide: 69,008
    • In cell biology: 4,098
  • Year to date:
    • Site-wide: 3,705
  • Since beginning of last month:
    • Site-wide: 18,355

CD300lf is the primary physiologic receptor of murine norovirus but not human norovirus

microbiology more details view paper
  • Downloaded 574 times
  • Download rankings, all-time:
    • Site-wide: 74,374
    • In microbiology: 4,590
  • Year to date:
    • Site-wide: 97,939
  • Since beginning of last month:
    • Site-wide: 77,049

Potent Neutralization of Omicron and other SARS-CoV-2 Variants of Concern by Biparatopic Human VH Domains

immunology more details view paper
  • Downloaded 560 times
  • Download rankings, all-time:
    • Site-wide: 76,541
    • In immunology: 3,236
  • Year to date:
    • Site-wide: 4,205
  • Since beginning of last month:
    • Site-wide: 20,060

Predicted Norovirus Resurgence in 2021-2022 Due to the Relaxation of Nonpharmaceutical Interventions Associated with COVID-19 Restrictions in England: A Mathematical Modelling Study

epidemiology more details view paper
  • Downloaded 547 times
  • Download rankings, all-time:
    • Site-wide: 78,728
    • In epidemiology: 3,649
  • Year to date:
    • Site-wide: 44,801
  • Since beginning of last month:
    • Site-wide: 37,777

Vandetanib Reduces Inflammatory Cytokines and Ameliorates COVID-19 in Infected Mice

immunology more details view paper
  • Downloaded 504 times
  • Download rankings, all-time:
    • Site-wide: 86,981
    • In immunology: 3,558
  • Year to date:
    • Site-wide: 7,141
  • Since beginning of last month:
    • Site-wide: 16,003

Thiol-based mucolytics exhibit antiviral activity against SARS-CoV-2 through allosteric disulfide disruption in the spike glycoprotein

microbiology more details view paper
  • Downloaded 484 times
  • Download rankings, all-time:
    • Site-wide: 90,779
    • In microbiology: 6,401
  • Year to date:
    • Site-wide: 52,459
  • Since beginning of last month:
    • Site-wide: 55,623

Content and performance of the MiniMUGA genotyping array, a new tool to improve rigor and reproducibility in mouse research

genetics more details view paper
  • Downloaded 453 times
  • Download rankings, all-time:
    • Site-wide: 97,640
    • In genetics: 3,687
  • Year to date:
    • Site-wide: 151,302
  • Since beginning of last month:
    • Site-wide: 154,179

Preadaptation of pandemic GII.4 noroviruses in hidden virus reservoirs years before emergence

evolutionary biology more details view paper
  • Downloaded 403 times
  • Download rankings, all-time:
    • Site-wide: 109,578
    • In evolutionary biology: 4,995
  • Year to date:
    • Site-wide: 159,491
  • Since beginning of last month:
    • Site-wide: 129,428

Zika virus infection in Collaborative Cross mice

microbiology more details view paper
  • Downloaded 402 times
  • Download rankings, all-time:
    • Site-wide: 109,879
    • In microbiology: 7,079
  • Year to date:
    • Site-wide: 167,681
  • Since beginning of last month:
    • Site-wide: 116,830

Diallel analysis reveals Mx1-dependent and Mx1-independent effects on response to influenza A virus in mice

genetics more details view paper
  • Downloaded 315 times
  • Download rankings, all-time:
    • Site-wide: 133,789
    • In genetics: 4,894
  • Year to date:
    • Site-wide: 184,920
  • Since beginning of last month:
    • Site-wide: 160,532

Genetic regulation of homeostatic immune architecture in the lungs of Collaborative Cross mice

genetics more details view paper
  • Downloaded 287 times
  • Download rankings, all-time:
    • Site-wide: 142,358
    • In genetics: 5,585
  • Year to date:
    • Site-wide: 64,976
  • Since beginning of last month:
    • Site-wide: 49,578

STAT5: A Target of Antagonism by Neurotropic Flaviviruses

microbiology more details view paper
  • Downloaded 270 times
  • Download rankings, all-time:
    • Site-wide: 147,246
    • In microbiology: 9,900
  • Year to date:
    • Site-wide: 178,272
  • Since beginning of last month:
    • Site-wide: 187,686

Genetically Engineered DENV Produces Antigenically Distinct Mature Particles

microbiology more details view paper
  • Downloaded 251 times
  • Download rankings, all-time:
    • Site-wide: 153,059
    • In microbiology: 10,911
  • Year to date:
    • Site-wide: 97,354
  • Since beginning of last month:
    • Site-wide: 109,967

A global map of the Zika virus phosphoproteome reveals host-driven regulation of viral budding

microbiology more details view paper
  • Downloaded 213 times
  • Download rankings, all-time:
    • Site-wide: 163,462
    • In microbiology: 12,480
  • Year to date:
    • Site-wide: 37,981
  • Since beginning of last month:
    • Site-wide: 60,584

Defining levels of dengue virus serotype-specific neutralizing antibodies induced by a live attenuated tetravalent dengue vaccine (TAK-003)

immunology more details view paper
  • Downloaded 196 times
  • Download rankings, all-time:
    • Site-wide: 167,907
    • In immunology: 4,910
  • Year to date:
    • Site-wide: 150,522
  • Since beginning of last month:
    • Site-wide: 101,732

Outcomes of convalescent plasma with defined high- versus lower-neutralizing antibody titers against SARS-CoV-2 among hospitalized patients: CoronaVirus Inactivating Plasma (CoVIP), double-blind phase 2 study.

infectious diseases more details view paper
  • Downloaded 188 times
  • Download rankings, all-time:
    • Site-wide: 169,781
    • In infectious diseases: None
  • Year to date:
    • Site-wide: 21,580
  • Since beginning of last month:
    • Site-wide: 3,020

PanLingua

News