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Author: Ralph S. Baric

Rankings

  • All-time downloads: 242,348 (rank: 183 )
  • Categories:
    • allergy and immunology: 384 (rank: 1,521 (tie) )
    • biochemistry: 6,608 (rank: 282 (tie) )
    • cell biology: 4,412 (rank: 972 (tie) )
    • evolutionary biology: 324 (rank: 18,124 (tie) )
    • genetics: 760 (rank: 19,556 (tie) )
    • immunology: 55,522 (rank: 104 )
    • infectious diseases: 3,829 (rank: 9,434 )
    • microbiology: 169,919 (rank: 36 )
    • pharmacology and toxicology: 590 (rank: 2,228 (tie) )

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Preprints

A broadly neutralizing antibody protects against SARS-CoV, pre-emergent bat CoVs, and SARS-CoV-2 variants in mice

microbiology more details view paper

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Common Mechanism of SARS-CoV and SARS-CoV-2 Pathogenesis across Species

microbiology more details view paper

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Severe acute respiratory syndrome-related coronavirus – The species and its viruses, a statement of the Coronavirus Study Group

microbiology more details view paper
  • Downloaded 110,539 times
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    • Site-wide: 37
    • In microbiology: 2
  • Year to date:
    • Site-wide: 149
  • Since beginning of last month:
    • Site-wide: 126

SARS-CoV-2 mRNA Vaccine Development Enabled by Prototype Pathogen Preparedness

immunology more details view paper
  • Downloaded 29,526 times
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    • Site-wide: 222
    • In immunology: 10
  • Year to date:
    • Site-wide: 249
  • Since beginning of last month:
    • Site-wide: 231

An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 and multiple endemic, epidemic and bat coronavirus

microbiology more details view paper
  • Downloaded 19,092 times
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    • Site-wide: 369
    • In microbiology: 41
  • Year to date:
    • Site-wide: 4,912
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A mouse-adapted SARS-CoV-2 model for the evaluation of COVID-19 medical countermeasures

microbiology more details view paper
  • Downloaded 8,999 times
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    • Site-wide: 964
    • In microbiology: 92
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    • Site-wide: 2,710
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LY-CoV555, a rapidly isolated potent neutralizing antibody, provides protection in a non-human primate model of SARS-CoV-2 infection

immunology more details view paper
  • Downloaded 6,567 times
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    • Site-wide: 1,420
    • In immunology: 34
  • Year to date:
    • Site-wide: 448
  • Since beginning of last month:
    • Site-wide: 1,375

Remdesivir potently inhibits SARS-CoV-2 in human lung cells and chimeric SARS-CoV expressing the SARS-CoV-2 RNA polymerase in mice.

microbiology more details view paper
  • Downloaded 4,852 times
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    • Site-wide: 2,170
    • In microbiology: 174
  • Year to date:
    • Site-wide: 8,347
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    • Site-wide: 12,489

Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein

immunology more details view paper
  • Downloaded 4,638 times
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    • Site-wide: 2,313
    • In immunology: 63
  • Year to date:
    • Site-wide: 11,529
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Newcastle disease virus (NDV) expressing the spike protein of SARS-CoV-2 as vaccine candidate

microbiology more details view paper
  • Downloaded 4,455 times
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    • Site-wide: 2,447
    • In microbiology: 184
  • Year to date:
    • Site-wide: 4,131
  • Since beginning of last month:
    • Site-wide: 3,096

Progenitor identification and SARS-CoV-2 infection in long-term human distal lung organoid cultures

cell biology more details view paper
  • Downloaded 4,412 times
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    • Site-wide: 2,480
    • In cell biology: 44
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    • Site-wide: 2,759
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    • Site-wide: 3,032

Specific viral RNA drives the SARS CoV-2 nucleocapsid to phase separate

biochemistry more details view paper
  • Downloaded 3,990 times
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    • Site-wide: 2,870
    • In biochemistry: 49
  • Year to date:
    • Site-wide: 4,012
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SARS-CoV-2 D614G Variant Exhibits Enhanced Replication ex vivo and Earlier Transmission in vivo

microbiology more details view paper
  • Downloaded 3,857 times
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    • Site-wide: 3,012
    • In microbiology: 212
  • Year to date:
    • Site-wide: 7,579
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    • Site-wide: 17,059

Potently neutralizing human antibodies that block SARS-CoV-2 receptor binding and protect animals

immunology more details view paper
  • Downloaded 3,720 times
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    • Site-wide: 3,169
    • In immunology: 93
  • Year to date:
    • Site-wide: 5,845
  • Since beginning of last month:
    • Site-wide: 7,183

Elicitation of potent neutralizing antibody responses by designed protein nanoparticle vaccines for SARS-CoV-2

immunology more details view paper
  • Downloaded 3,650 times
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    • Site-wide: 3,268
    • In immunology: 97
  • Year to date:
    • Site-wide: 8,843
  • Since beginning of last month:
    • Site-wide: 5,384

Rapid selection of a human monoclonal antibody that potently neutralizes SARS-CoV-2 in two animal models

microbiology more details view paper
  • Downloaded 3,036 times
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    • Site-wide: 4,232
    • In microbiology: 270
  • Year to date:
    • Site-wide: 9,451
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    • Site-wide: 12,744

Cryo-electron Microscopy and Exploratory Antisense Targeting of the 28-kDa Frameshift Stimulation Element from the SARS-CoV-2 RNA Genome

biochemistry more details view paper
  • Downloaded 2,618 times
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    • Site-wide: 5,216
    • In biochemistry: 88
  • Year to date:
    • Site-wide: 3,251
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    • Site-wide: 4,595

The RBD Of The Spike Protein Of SARS-Group Coronaviruses Is A Highly Specific Target Of SARS-CoV-2 Antibodies But Not Other Pathogenic Human and Animal Coronavirus Antibodies

infectious diseases more details view paper
  • Downloaded 2,576 times
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    • Site-wide: 5,332
    • In infectious diseases: 875
  • Year to date:
    • Site-wide: 7,289
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    • Site-wide: 6,875

Broad sarbecovirus neutralizing antibodies define a key site of vulnerability on the SARS-CoV-2 spike protein

immunology more details view paper
  • Downloaded 2,307 times
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    • Site-wide: 6,316
    • In immunology: 191
  • Year to date:
    • Site-wide: 18,899
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    • Site-wide: 17,026

Combination attenuation offers strategy for live-attenuated coronavirus vaccines

microbiology more details view paper
  • Downloaded 2,264 times
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    • Site-wide: 6,485
    • In microbiology: 376
  • Year to date:
    • Site-wide: 28,345
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Mucin 4 Protects Female Mice from Coronavirus Pathogenesis

microbiology more details view paper
  • Downloaded 2,202 times
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    • Site-wide: 6,740
    • In microbiology: 392
  • Year to date:
    • Site-wide: 25,350
  • Since beginning of last month:
    • Site-wide: 22,538

A Newcastle disease virus (NDV) expressing membrane-anchored spike as a cost-effective inactivated SARS-CoV-2 vaccine

microbiology more details view paper
  • Downloaded 1,772 times
  • Download rankings, all-time:
    • Site-wide: 9,347
    • In microbiology: 535
  • Year to date:
    • Site-wide: 10,214
  • Since beginning of last month:
    • Site-wide: 5,293

An Engineered Antibody with Broad Protective Efficacy in Murine Models of SARS and COVID-19

immunology more details view paper
  • Downloaded 1,521 times
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    • Site-wide: 11,637
    • In immunology: 338
  • Year to date:
    • Site-wide: 3,358
  • Since beginning of last month:
    • Site-wide: 5,048

Trypsin treatment unlocks barrier for zoonotic coronaviruses infection

microbiology more details view paper
  • Downloaded 1,445 times
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    • Site-wide: 12,587
    • In microbiology: 711
  • Year to date:
    • Site-wide: 36,524
  • Since beginning of last month:
    • Site-wide: 38,600

Antibody potency, effector function and combinations in protection from SARS-CoV-2 infection in vivo

microbiology more details view paper
  • Downloaded 1,416 times
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    • Site-wide: 13,010
    • In microbiology: 738
  • Year to date:
    • Site-wide: 10,009
  • Since beginning of last month:
    • Site-wide: 23,741

Evaluation of SARS-CoV-2 neutralization assays for antibody monitoring in natural infection and vaccine trials

infectious diseases more details view paper
  • Downloaded 1,253 times
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    • Site-wide: 15,681
    • In infectious diseases: 1,560
  • Year to date:
    • Site-wide: 1,812
  • Since beginning of last month:
    • Site-wide: 3,182

Prevention and therapy of SARS-CoV-2 and the B.1.351 variant in mice

microbiology more details view paper
  • Downloaded 1,248 times
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    • Site-wide: 15,753
    • In microbiology: 908
  • Year to date:
    • Site-wide: 1,163
  • Since beginning of last month:
    • Site-wide: 428

High-density amplicon sequencing identifies community spread and ongoing evolution of SARS-CoV-2 in the Southern United States

microbiology more details view paper
  • Downloaded 1,192 times
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    • Site-wide: 16,869
    • In microbiology: 969
  • Year to date:
    • Site-wide: 17,080
  • Since beginning of last month:
    • Site-wide: 9,485

Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes in COVID-19 convalescent plasma

immunology more details view paper
  • Downloaded 1,170 times
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    • Site-wide: 17,340
    • In immunology: 515
  • Year to date:
    • Site-wide: 2,092
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    • Site-wide: 6,655

Comparative analysis of coronavirus genomic RNA structure reveals conservation in SARS-like coronaviruses

microbiology more details view paper
  • Downloaded 1,081 times
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    • Site-wide: 19,480
    • In microbiology: 1,096
  • Year to date:
    • Site-wide: 17,277
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    • Site-wide: 28,350

Cross-reactive coronavirus antibodies with diverse epitope specificities and extra-neutralization functions

immunology more details view paper
  • Downloaded 999 times
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    • Site-wide: 21,811
    • In immunology: 655
  • Year to date:
    • Site-wide: 2,246
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    • Site-wide: 4,610

Chimeric spike mRNA vaccines protect against Sarbecovirus challenge in mice

microbiology more details view paper
  • Downloaded 724 times
  • Download rankings, all-time:
    • Site-wide: 34,379
    • In microbiology: 2,060
  • Year to date:
    • Site-wide: 2,499
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    • Site-wide: None

MERS-CoV NSP16 necessary for IFN resistance and viral pathogenesis

microbiology more details view paper
  • Downloaded 694 times
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    • Site-wide: 36,452
    • In microbiology: 2,178
  • Year to date:
    • Site-wide: 53,563
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    • Site-wide: 76,089

Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines

immunology more details view paper
  • Downloaded 690 times
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    • Site-wide: 36,737
    • In immunology: 1,074
  • Year to date:
    • Site-wide: 2,658
  • Since beginning of last month:
    • Site-wide: 1,743

Baseline T cell immune phenotypes predict virologic and disease control upon SARS-CoV infection

immunology more details view paper
  • Downloaded 613 times
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    • Site-wide: 42,793
    • In immunology: 1,228
  • Year to date:
    • Site-wide: 34,474
  • Since beginning of last month:
    • Site-wide: 33,191

Repurposing the Ebola and Marburg Virus Inhibitors Tilorone, Quinacrine and Pyronaridine: In vitro Activity Against SARS-CoV-2 and Potential Mechanisms

pharmacology and toxicology more details view paper
  • Downloaded 590 times
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    • Site-wide: 44,924
    • In pharmacology and toxicology: 261
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    • Site-wide: 11,905
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    • Site-wide: 31,826

CD300lf is the primary physiologic receptor of murine norovirus but not human norovirus

microbiology more details view paper
  • Downloaded 471 times
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    • Site-wide: 58,581
    • In microbiology: 3,793
  • Year to date:
    • Site-wide: 91,783
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    • Site-wide: 98,795

Sex disparities and neutralizing antibody durability to SARS-CoV-2 infection in convalescent individuals

allergy and immunology more details view paper
  • Downloaded 384 times
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    • Site-wide: 71,982
    • In allergy and immunology: 95
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    • Site-wide: 6,281
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    • Site-wide: 12,559

Content and performance of the MiniMUGA genotyping array, a new tool to improve rigor and reproducibility in mouse research

genetics more details view paper
  • Downloaded 370 times
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    • Site-wide: 74,369
    • In genetics: 3,363
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    • Site-wide: 43,697
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    • Site-wide: 38,556

Preadaptation of pandemic GII.4 noroviruses in hidden virus reservoirs years before emergence

evolutionary biology more details view paper
  • Downloaded 324 times
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    • Site-wide: 83,176
    • In evolutionary biology: 4,472
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    • Site-wide: 95,620

Zika virus infection in Collaborative Cross mice

microbiology more details view paper
  • Downloaded 320 times
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    • Site-wide: 83,988
    • In microbiology: 5,852
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    • Site-wide: 114,963
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    • Site-wide: 107,717

Diallel analysis reveals Mx1-dependent and Mx1-independent effects on response to influenza A virus in mice

genetics more details view paper
  • Downloaded 274 times
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    • Site-wide: 93,965
    • In genetics: 4,176
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    • Site-wide: 129,103
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    • Site-wide: 133,533

STAT5: A Target of Antagonism by Neurotropic Flaviviruses

microbiology more details view paper
  • Downloaded 215 times
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    • Site-wide: 107,313
    • In microbiology: 7,870
  • Year to date:
    • Site-wide: 119,080
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    • Site-wide: 111,186

Defining levels of dengue virus serotype-specific neutralizing antibodies induced by a live attenuated tetravalent dengue vaccine (TAK-003)

immunology more details view paper
  • Downloaded 121 times
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    • Site-wide: 127,570
    • In immunology: 3,711
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    • Site-wide: 72,940
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    • Site-wide: 99,231

Genetic regulation of homeostatic immune architecture in the lungs of Collaborative Cross mice

genetics more details view paper
  • Downloaded 116 times
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    • Site-wide: 128,555
    • In genetics: 5,351
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    • Site-wide: 30,212
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    • Site-wide: 5,903

Genetically Engineered DENV Produces Antigenically Distinct Mature Particles

microbiology more details view paper
  • Downloaded 45 times
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    • Site-wide: 138,043
    • In microbiology: 10,726
  • Year to date:
    • Site-wide: 71,481
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    • Site-wide: 19,114

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