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Author: Yan Wu

Rankings

  • All-time downloads: 48,420 (rank: 4,961 )
  • Categories:
    • biochemistry: 2,297 (rank: 2,435 )
    • bioinformatics: 5,078 (rank: 3,012 )
    • biophysics: 1,687 (rank: 3,921 (tie) )
    • cancer biology: 133 (rank: 44,406 (tie) )
    • cell biology: 824 (rank: 15,925 (tie) )
    • epidemiology: 933 (rank: 14,141 (tie) )
    • genetics: 598 (rank: 27,567 (tie) )
    • genomics: 3,025 (rank: 9,629 (tie) )
    • immunology: 460 (rank: 28,447 (tie) )
    • infectious diseases: 3,212 (rank: 16,355 (tie) )
    • microbiology: 7,187 (rank: 2,757 )
    • molecular biology: 5,071 (rank: 815 (tie) )
    • neuroscience: 941 (rank: 34,601 (tie) )
    • pathology: 6,477 (rank: 295 (tie) )
    • pharmacology and toxicology: 3,088 (rank: 390 )
    • plant biology: 1,120 (rank: 4,872 (tie) )
    • synthetic biology: 615 (rank: 4,287 (tie) )
    • systems biology: 389 (rank: 12,517 (tie) )
    • zoology: 295 (rank: 2,598 (tie) )

Downloads per author, site-wide

Preprints

Calcium channel blocker amlodipine besylate is associated with reduced case fatality rate of COVID-19 patients with hypertension

pathology more details view paper
  • Downloaded 6,598 times
  • Download rankings, all-time:
    • Site-wide: 2,181
    • In pathology: 19
  • Year to date:
    • Site-wide: 24,761
  • Since beginning of last month:
    • Site-wide: 34,646

Novel and potent inhibitors targeting DHODH, a rate-limiting enzyme in de novo pyrimidine biosynthesis, are broad-spectrum antiviral against RNA viruses including newly emerged coronavirus SARS-CoV-2

microbiology more details view paper
  • Downloaded 5,615 times
  • Download rankings, all-time:
    • Site-wide: 2,706
    • In microbiology: 207
  • Year to date:
    • Site-wide: 22,594
  • Since beginning of last month:
    • Site-wide: 24,317

Discovery of baicalin and baicalein as novel, natural product inhibitors of SARS-CoV-2 3CL protease in vitro

molecular biology more details view paper
  • Downloaded 5,327 times
  • Download rankings, all-time:
    • Site-wide: 2,920
    • In molecular biology: 54
  • Year to date:
    • Site-wide: 6,566
  • Since beginning of last month:
    • Site-wide: 8,177

Visualizing and interpreting single-cell gene expression datasets with Similarity Weighted Nonnegative Embedding

bioinformatics more details view paper
  • Downloaded 4,740 times
  • Download rankings, all-time:
    • Site-wide: 3,403
    • In bioinformatics: 241
  • Year to date:
    • Site-wide: 69,587
  • Since beginning of last month:
    • Site-wide: 94,097

An atlas of healthy and injured cell states and niches in the human kidney

genomics more details view paper
  • Downloaded 3,271 times
  • Download rankings, all-time:
    • Site-wide: 5,753
    • In genomics: 844
  • Year to date:
    • Site-wide: 1,189
  • Since beginning of last month:
    • Site-wide: 996

A non-competing pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2

infectious diseases more details view paper
  • Downloaded 3,263 times
  • Download rankings, all-time:
    • Site-wide: 5,772
    • In infectious diseases: 1,083
  • Year to date:
    • Site-wide: 62,977
  • Since beginning of last month:
    • Site-wide: 65,965

Immunoglobulin fragment F(ab')2 against RBD potently neutralizes SARS-CoV-2 in vitro

pharmacology and toxicology more details view paper
  • Downloaded 2,238 times
  • Download rankings, all-time:
    • Site-wide: 9,987
    • In pharmacology and toxicology: 54
  • Year to date:
    • Site-wide: 103,407
  • Since beginning of last month:
    • Site-wide: 103,405

Structural basis for the inhibition of SARS-CoV-2 main protease by antineoplastic drug Carmofur

biochemistry more details view paper
  • Downloaded 1,786 times
  • Download rankings, all-time:
    • Site-wide: 14,011
    • In biochemistry: 271
  • Year to date:
    • Site-wide: 78,295
  • Since beginning of last month:
    • Site-wide: 70,880

Cryo-EM Structure of the Human Mitochondrial Translocase TIM22 Complex

biophysics more details view paper
  • Downloaded 1,707 times
  • Download rankings, all-time:
    • Site-wide: 14,984
    • In biophysics: 319
  • Year to date:
    • Site-wide: 122,710
  • Since beginning of last month:
    • Site-wide: 121,054

Omicron-specific mRNA vaccine elicits potent immune responses in mice, hamsters, and nonhuman primates

microbiology more details view paper
  • Downloaded 1,090 times
  • Download rankings, all-time:
    • Site-wide: 29,898
    • In microbiology: None
  • Year to date:
    • Site-wide: 1,475
  • Since beginning of last month:
    • Site-wide: 1,391

SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damage and constitutes an antiviral target

microbiology more details view paper
  • Downloaded 1,041 times
  • Download rankings, all-time:
    • Site-wide: 32,008
    • In microbiology: 1,762
  • Year to date:
    • Site-wide: 106,711
  • Since beginning of last month:
    • Site-wide: 96,558

Transmission dynamics of SARS-COV-2 in China: impact of public health interventions

epidemiology more details view paper
  • Downloaded 951 times
  • Download rankings, all-time:
    • Site-wide: 36,667
    • In epidemiology: 1,865
  • Year to date:
    • Site-wide: 145,284
  • Since beginning of last month:
    • Site-wide: 138,110

A Polybasic Domain in aPKC Mediates Par-6-Dependent Control of Plasma Membrane Targeting and Kinase Activity

cell biology more details view paper
  • Downloaded 842 times
  • Download rankings, all-time:
    • Site-wide: 43,911
    • In cell biology: 1,607
  • Year to date:
    • Site-wide: 121,571
  • Since beginning of last month:
    • Site-wide: 144,771

Revealing the transcription factor regulatory context of human specific cortical development using single-cell multi-omics

genomics more details view paper
  • Downloaded 784 times
  • Download rankings, all-time:
    • Site-wide: 48,717
    • In genomics: 4,012
  • Year to date:
    • Site-wide: 31,728
  • Since beginning of last month:
    • Site-wide: 13,807

A novel platform of RNA 2-O-methylation high-throughput and site-specific quantification tools revealed its broad distribution

biochemistry more details view paper
  • Downloaded 742 times
  • Download rankings, all-time:
    • Site-wide: 52,777
    • In biochemistry: 1,910
  • Year to date:
    • Site-wide: 19,821
  • Since beginning of last month:
    • Site-wide: 15,179

An rpw8 quadruple mutant of Arabidopsis Col-0 is partially compromised in bacterial and fungal resistance

plant biology more details view paper
  • Downloaded 660 times
  • Download rankings, all-time:
    • Site-wide: 62,092
    • In plant biology: 1,426
  • Year to date:
    • Site-wide: 62,986
  • Since beginning of last month:
    • Site-wide: 57,244

Modular Thermal Control of Protein Dimerization

synthetic biology more details view paper
  • Downloaded 633 times
  • Download rankings, all-time:
    • Site-wide: 65,628
    • In synthetic biology: 742
  • Year to date:
    • Site-wide: 156,895
  • Since beginning of last month:
    • Site-wide: 145,467

Cell signaling coordinates global Polycomb Repressive Complex 2 recruitment and gene expression in murine embryonic stem cells

genetics more details view paper
  • Downloaded 628 times
  • Download rankings, all-time:
    • Site-wide: 66,265
    • In genetics: 2,635
  • Year to date:
    • Site-wide: 104,859
  • Since beginning of last month:
    • Site-wide: 93,431

Single-dose AAV-based vaccine induces a high level of neutralizing antibodies against SARS-CoV-2 in rhesus macaques

immunology more details view paper
  • Downloaded 621 times
  • Download rankings, all-time:
    • Site-wide: 67,291
    • In immunology: 2,477
  • Year to date:
    • Site-wide: 26,100
  • Since beginning of last month:
    • Site-wide: 8,283

Broad-spectrum antivirals of protoporphyrins inhibit the entry of highly pathogenic emerging viruses

pharmacology and toxicology more details view paper
  • Downloaded 478 times
  • Download rankings, all-time:
    • Site-wide: 92,274
    • In pharmacology and toxicology: 557
  • Year to date:
    • Site-wide: 176,589
  • Since beginning of last month:
    • Site-wide: 158,585

Charting oncogenicity of genes and variants across lineages via multiplexed screens in teratomas

systems biology more details view paper
  • Downloaded 451 times
  • Download rankings, all-time:
    • Site-wide: 98,210
    • In systems biology: 2,193
  • Year to date:
    • Site-wide: 68,932
  • Since beginning of last month:
    • Site-wide: 22,807

Structural insight into the mechanism of neuraminidase inhibitor-resistant mutations in human-infecting H10N8 Influenza A virus

microbiology more details view paper
  • Downloaded 446 times
  • Download rankings, all-time:
    • Site-wide: 99,341
    • In microbiology: 6,249
  • Year to date:
    • Site-wide: 137,988
  • Since beginning of last month:
    • Site-wide: 104,687

A cocktail containing two synergetic antibodies broadly neutralizes SARS-CoV-2 and its variants including Omicron BA.1 and BA.2

immunology more details view paper
  • Downloaded 441 times
  • Download rankings, all-time:
    • Site-wide: 100,642
    • In immunology: None
  • Year to date:
    • Site-wide: 6,023
  • Since beginning of last month:
    • Site-wide: 2,771

Optimization of Spectral Library Size Improves DIA-MS Proteome Coverage

bioinformatics more details view paper
  • Downloaded 424 times
  • Download rankings, all-time:
    • Site-wide: 104,580
    • In bioinformatics: 8,800
  • Year to date:
    • Site-wide: 85,266
  • Since beginning of last month:
    • Site-wide: 84,890

Loss of ASH1L in developing brains causes autistic-like behaviors in a mouse model

neuroscience more details view paper
  • Downloaded 423 times
  • Download rankings, all-time:
    • Site-wide: 104,615
    • In neuroscience: 14,940
  • Year to date:
    • Site-wide: 123,365
  • Since beginning of last month:
    • Site-wide: 153,683

Loss of O-GlcNAcylation on MeCP2 Thr 203 Leads to Neurodevelopmental Disorders

neuroscience more details view paper
  • Downloaded 405 times
  • Download rankings, all-time:
    • Site-wide: 109,079
    • In neuroscience: 15,146
  • Year to date:
    • Site-wide: 115,340
  • Since beginning of last month:
    • Site-wide: 152,112

Co-Expression Network-based Analysis associated with potato initial resistance

plant biology more details view paper
  • Downloaded 371 times
  • Download rankings, all-time:
    • Site-wide: 117,895
    • In plant biology: 3,141
  • Year to date:
    • Site-wide: 93,998
  • Since beginning of last month:
    • Site-wide: 67,103

Investigation of novel functions of three genes in oriental river prawn, Macrobrachium nipponense: Molecular Cloning, Expression, and In situ Hybridization Analysis

zoology more details view paper
  • Downloaded 314 times
  • Download rankings, all-time:
    • Site-wide: 134,050
    • In zoology: 497
  • Year to date:
    • Site-wide: 147,899
  • Since beginning of last month:
    • Site-wide: 162,576

A-to-I mRNA editing in a ferric siderophore receptor improves competition for iron in Xanthomonas oryzae

microbiology more details view paper
  • Downloaded 310 times
  • Download rankings, all-time:
    • Site-wide: 135,325
    • In microbiology: 9,627
  • Year to date:
    • Site-wide: 97,539
  • Since beginning of last month:
    • Site-wide: 75,477

Structure selected RBM immunogens prime polyclonal memory responses that neutralize SARS-CoV-2 variants of concern

immunology more details view paper
  • Downloaded 300 times
  • Download rankings, all-time:
    • Site-wide: 138,503
    • In immunology: 4,066
  • Year to date:
    • Site-wide: 80,535
  • Since beginning of last month:
    • Site-wide: 90,399

Harringtonine has the effects of double blocking SARS-CoV-2 membrane fusion

pharmacology and toxicology more details view paper
  • Downloaded 279 times
  • Download rankings, all-time:
    • Site-wide: 144,739
    • In pharmacology and toxicology: 1,201
  • Year to date:
    • Site-wide: 12,094
  • Since beginning of last month:
    • Site-wide: 47,996

Hetero-bivalent Nanobodies Provide Broad-spectrum Protection against SARS-CoV-2 Variants of Concern including Omicron

immunology more details view paper
  • Downloaded 249 times
  • Download rankings, all-time:
    • Site-wide: 153,639
    • In immunology: None
  • Year to date:
    • Site-wide: 14,343
  • Since beginning of last month:
    • Site-wide: 38,068

CD47 cross-dressing by extracellular vesicles expressing CD47 inhibits phagocytosis without transmitting cell death signals

immunology more details view paper
  • Downloaded 244 times
  • Download rankings, all-time:
    • Site-wide: 154,877
    • In immunology: 4,823
  • Year to date:
    • Site-wide: 50,703
  • Since beginning of last month:
    • Site-wide: 50,216

Rice LEAFY COTYLEDON1 hinders photosynthesis in the embryo development to promote seed dormancy

plant biology more details view paper
  • Downloaded 209 times
  • Download rankings, all-time:
    • Site-wide: 164,591
    • In plant biology: 4,486
  • Year to date:
    • Site-wide: 62,788
  • Since beginning of last month:
    • Site-wide: 65,096

An in silico exploration of combining Interleukin-12 with Oxaliplatin to treat liver-metastatic colorectal cancer

pharmacology and toxicology more details view paper
  • Downloaded 206 times
  • Download rankings, all-time:
    • Site-wide: 165,183
    • In pharmacology and toxicology: 1,290
  • Year to date:
    • Site-wide: 166,265
  • Since beginning of last month:
    • Site-wide: 147,183

BMSCs differentiated into neurons, astrocytes and oligodendrocytesalleviatedthe inflammation and demyelination of EAE mice models

neuroscience more details view paper
  • Downloaded 175 times
  • Download rankings, all-time:
    • Site-wide: 172,940
    • In neuroscience: 24,177
  • Year to date:
    • Site-wide: 135,964
  • Since beginning of last month:
    • Site-wide: 182,639

Histone H3K36me2-specific methyltransferase ASH1L is required for the MLL-AF9-induced leukemogenesis

cancer biology more details view paper
  • Downloaded 158 times
  • Download rankings, all-time:
    • Site-wide: 176,640
    • In cancer biology: 5,193
  • Year to date:
    • Site-wide: 102,609
  • Since beginning of last month:
    • Site-wide: 133,392

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