Author: Victor Nizet

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Preprints

Chemical Impacts of the Microbiome Across Scales Reveal Novel Conjugated Bile Acids

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  • Site-wide: 12,826
  • In microbiology: 724
• Year to date:
  • Site-wide: 91,820
• Since beginning of last month:
  • Site-wide: 100,392

Evidence that recurrent Group A streptococcus tonsillitis is an immunosusceptibility disease involving antibody deficiency and aberrant Tfh cells

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  • Site-wide: 22,901
  • In immunology: 670
• Year to date:
  • Site-wide: 75,577
• Since beginning of last month:
  • Site-wide: 70,060

Exploration of bacterial bottlenecks and Streptococcus pneumoniae pathogenesis by CRISPRi-seq

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  • Site-wide: 29,633
  • In microbiology: 1,752
• Year to date:
  • Site-wide: 23,982
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  • Site-wide: 18,025

Streptococcal Lancefield polysaccharides are critical cell wall determinants for human group IIA secreted phospholipase A2 to exert its bactericidal effects

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  • Site-wide: 56,282
  • In microbiology: 3,654
• Year to date:
  • Site-wide: 88,170
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  • Site-wide: 65,201

Revealing 29 sets of independently modulated genes in Staphylococcus aureus, their regulators and role in key physiological responses

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  • Site-wide: 70,624
  • In microbiology: 4,806
• Year to date:
  • Site-wide: 125,577
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  • Site-wide: 120,432

Repurposed Drugs Block Toxin-Driven Platelet Clearance by the Hepatic Ashwell-Morell Receptor to Clear Staphylococcus aureus Bacteremia

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  • Site-wide: 80,006
  • In microbiology: 5,576
• Year to date:
  • Site-wide: 36,332
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  • Site-wide: 23,655

TLR4 signaling and macrophage inflammatory responses are dampened by GIV/Girdin

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  • Site-wide: 84,041
  • In immunology: 2,332
• Year to date:
  • Site-wide: 33,441
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  • Site-wide: 24,766

Decomposition of transcriptional responses provides insights into differential antibiotic susceptibility

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  • Site-wide: 88,728
  • In microbiology: 6,298
• Year to date:
  • Site-wide: 74,452
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  • Site-wide: 74,054

Upon microbial challenge human neutrophils undergo rapid changes in nuclear architecture to orchestrate an immediate inflammatory gene program

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  • Site-wide: 90,249
  • In genomics: 5,646
• Year to date:
  • Site-wide: 116,799
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  • Site-wide: 93,704

Characterizing the response of Acinetobacter baumannii ATCC 17978 to azithromycin in multiple in vitro growth conditions

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  • Site-wide: 92,907
  • In microbiology: 6,690
• Year to date:
  • Site-wide: 31,501
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  • Site-wide: 23,600

Role of Inflammasome-independent Activation of IL-1β by the Pseudomonas aeruginosa Protease LasB

• Downloaded 252 times
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  • Site-wide: 94,971
  • In microbiology: 6,867
• Year to date:
  • Site-wide: 80,560
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  • Site-wide: 95,404

Prophage exotoxins enhance colonization fitness in epidemic scarlet fever-causing Streptococcus pyogenes

• Downloaded 208 times
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  • Site-wide: 104,835
  • In microbiology: 7,724
• Year to date:
  • Site-wide: 131,368
• Since beginning of last month:
  • Site-wide: 131,043

Identifying the effect of vancomycin on HA-MRSA strains using bacteriological and physiological media

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  • Site-wide: 104,854
  • In microbiology: 7,722
• Year to date:
  • Site-wide: 25,345
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  • Site-wide: 119,207

PHLPP1 Counter-regulates STAT1-mediated Inflammatory Signaling

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  • Site-wide: 105,788
  • In biochemistry: 3,091
• Year to date:
  • Site-wide: 132,815
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  • Site-wide: 125,040

Environmental conditions dictate differential evolution of vancomycin resistance in Staphylococcus aureus

• Downloaded 192 times
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  • Site-wide: 108,169
  • In microbiology: 8,035
• Year to date:
  • Site-wide: 95,061
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  • Site-wide: 75,762

CCL28 modulates neutrophil responses and impacts the trajectory of mucosal infections

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  • Site-wide: 121,036
  • In immunology: 3,441
• Year to date:
  • Site-wide: 17,729
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  • Site-wide: 4,550

Profiling the effect of nafcillin on HA-MRSA D592 using bacteriological and physiological media

• Downloaded 128 times
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  • Site-wide: 121,523
  • In microbiology: 9,251
• Year to date:
  • Site-wide: 103,911
• Since beginning of last month:
  • Site-wide: 92,653