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Author: Michael V. Holmes

Rankings

  • All-time downloads: 22,825 (rank: 7,282 (tie) )
  • Categories:
    • cardiovascular medicine: 1,528 (rank: 212 )
    • endocrinology: 143 (rank: 926 (tie) )
    • epidemiology: 8,374 (rank: 1,521 )
    • genetics: 11,206 (rank: 1,357 )
    • genomics: 909 (rank: 23,562 (tie) )
    • infectious diseases: 476 (rank: 29,367 (tie) )
    • pharmacology and therapeutics: 189 (rank: 698 (tie) )

Downloads per author, site-wide

Preprints

Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases

genetics more details view paper
  • Downloaded 3,834 times
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    • Site-wide: 2,908
    • In genetics: 113
  • Year to date:
    • Site-wide: 9,168
  • Since beginning of last month:
    • Site-wide: 8,930

Cannabis use and risk of schizophrenia: a Mendelian randomization study

epidemiology more details view paper
  • Downloaded 2,393 times
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    • Site-wide: 5,733
    • In epidemiology: 485
  • Year to date:
    • Site-wide: 52,735
  • Since beginning of last month:
    • Site-wide: 52,517

Genomic evaluation of circulating proteins for drug target characterisation and precision medicine

genetics more details view paper
  • Downloaded 2,292 times
  • Download rankings, all-time:
    • Site-wide: 6,127
    • In genetics: 290
  • Year to date:
    • Site-wide: 7,670
  • Since beginning of last month:
    • Site-wide: 10,567

Genome-wide association study provides new insights into the genetic architecture and pathogenesis of heart failure

genetics more details view paper
  • Downloaded 1,475 times
  • Download rankings, all-time:
    • Site-wide: 11,693
    • In genetics: 568
  • Year to date:
    • Site-wide: 80,284
  • Since beginning of last month:
    • Site-wide: 77,870

Lifelong genetically lowered sclerostin and risk of cardiovascular disease.

genetics more details view paper
  • Downloaded 1,225 times
  • Download rankings, all-time:
    • Site-wide: 15,557
    • In genetics: 767
  • Year to date:
    • Site-wide: 57,251
  • Since beginning of last month:
    • Site-wide: 71,916

Causal relationships between obesity and the leading causes of death in women and men

epidemiology more details view paper
  • Downloaded 971 times
  • Download rankings, all-time:
    • Site-wide: 21,840
    • In epidemiology: 1,256
  • Year to date:
    • Site-wide: 87,637
  • Since beginning of last month:
    • Site-wide: 106,630

GWAS identifies novel risk locus for erectile dysfunction and implicates hypothalamic neurobiology and diabetes in etiology

genomics more details view paper
  • Downloaded 909 times
  • Download rankings, all-time:
    • Site-wide: 24,069
    • In genomics: 2,312
  • Year to date:
    • Site-wide: 121,321
  • Since beginning of last month:
    • Site-wide: 118,379

Apolipoprotein B underlies the causal relationship of circulating blood lipids with coronary heart disease

cardiovascular medicine more details view paper
  • Downloaded 908 times
  • Download rankings, all-time:
    • Site-wide: 24,139
    • In cardiovascular medicine: 34
  • Year to date:
    • Site-wide: 70,561
  • Since beginning of last month:
    • Site-wide: 58,300

Metabolomic consequences of genetic inhibition of PCSK9 compared with statin treatment

epidemiology more details view paper
  • Downloaded 652 times
  • Download rankings, all-time:
    • Site-wide: 38,088
    • In epidemiology: 1,836
  • Year to date:
    • Site-wide: 120,770
  • Since beginning of last month:
    • Site-wide: 129,293

Education and coronary heart disease: a Mendelian randomization study

epidemiology more details view paper
  • Downloaded 644 times
  • Download rankings, all-time:
    • Site-wide: 38,701
    • In epidemiology: 1,860
  • Year to date:
    • Site-wide: 120,909
  • Since beginning of last month:
    • Site-wide: 119,490

Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9

genetics more details view paper
  • Downloaded 574 times
  • Download rankings, all-time:
    • Site-wide: 44,687
    • In genetics: 2,094
  • Year to date:
    • Site-wide: 69,473
  • Since beginning of last month:
    • Site-wide: 113,560

Proof of concept for quantitative urine NMR metabolomics pipeline for large-scale epidemiology and genetics

epidemiology more details view paper
  • Downloaded 568 times
  • Download rankings, all-time:
    • Site-wide: 45,269
    • In epidemiology: 2,102
  • Year to date:
    • Site-wide: 110,486
  • Since beginning of last month:
    • Site-wide: 90,129

Genome-wide study identifies association between HLA-B*55:01 and penicillin allergy

genetics more details view paper
  • Downloaded 567 times
  • Download rankings, all-time:
    • Site-wide: 45,386
    • In genetics: 2,136
  • Year to date:
    • Site-wide: 52,826
  • Since beginning of last month:
    • Site-wide: 56,368

What explains the effect of education on cardiovascular disease? Applying Mendelian randomization to identify the consequences of education inequality

epidemiology more details view paper
  • Downloaded 505 times
  • Download rankings, all-time:
    • Site-wide: 52,132
    • In epidemiology: 2,304
  • Year to date:
    • Site-wide: 119,574
  • Since beginning of last month:
    • Site-wide: 106,287

Genetic inhibition of interleukin-6 receptor signaling and Covid-19

infectious diseases more details view paper
  • Downloaded 476 times
  • Download rankings, all-time:
    • Site-wide: 55,842
    • In infectious diseases: 2,787
  • Year to date:
    • Site-wide: 73,609
  • Since beginning of last month:
    • Site-wide: 58,894

Direct estimation of HDL-mediated cholesterol efflux capacity from serum

epidemiology more details view paper
  • Downloaded 469 times
  • Download rankings, all-time:
    • Site-wide: 56,660
    • In epidemiology: 2,453
  • Year to date:
    • Site-wide: 105,429
  • Since beginning of last month:
    • Site-wide: 97,698

PCSK9 genetic variants, life-long lowering of LDL-cholesterol and cognition: a large-scale Mendelian randomization study

epidemiology more details view paper
  • Downloaded 450 times
  • Download rankings, all-time:
    • Site-wide: 59,222
    • In epidemiology: 2,561
  • Year to date:
    • Site-wide: 66,576
  • Since beginning of last month:
    • Site-wide: 60,691

Colocalization highlights genes in hypothalamic–pituitary–gonadal axis as potentially mediating polycystic ovary syndrome risk

genetics more details view paper
  • Downloaded 444 times
  • Download rankings, all-time:
    • Site-wide: 60,034
    • In genetics: 2,788
  • Year to date:
    • Site-wide: 50,276
  • Since beginning of last month:
    • Site-wide: 46,436

CETP inhibition and ADCY9 genotype: evidence of a qualitative pharmacogenetic interaction in cardiovascular disease?

genetics more details view paper
  • Downloaded 428 times
  • Download rankings, all-time:
    • Site-wide: 62,353
    • In genetics: 2,885
  • Year to date:
    • Site-wide: 66,994
  • Since beginning of last month:
    • Site-wide: 45,366

Lipoprotein Signatures of Cholesteryl Ester Transfer Protein and HMG-CoA Reductase Inhibition

genetics more details view paper
  • Downloaded 367 times
  • Download rankings, all-time:
    • Site-wide: 72,194
    • In genetics: 3,295
  • Year to date:
    • Site-wide: 103,164
  • Since beginning of last month:
    • Site-wide: 89,148

Effects of apolipoprotein B on the lifespan and risks of major disease including type 2 diabetes: a Mendelian randomization analysis using outcomes in first-degree relatives

epidemiology more details view paper
  • Downloaded 357 times
  • Download rankings, all-time:
    • Site-wide: 74,019
    • In epidemiology: 3,103
  • Year to date:
    • Site-wide: 39,167
  • Since beginning of last month:
    • Site-wide: 32,362

Genetic variation in apolipoprotein A-I concentrations and risk of coronary artery disease

epidemiology more details view paper
  • Downloaded 324 times
  • Download rankings, all-time:
    • Site-wide: 80,353
    • In epidemiology: 3,331
  • Year to date:
    • Site-wide: 115,095
  • Since beginning of last month:
    • Site-wide: 118,366

Assessing the efficacy and safety of angiotensinogen inhibition using human genetics

cardiovascular medicine more details view paper
  • Downloaded 315 times
  • Download rankings, all-time:
    • Site-wide: 82,053
    • In cardiovascular medicine: 126
  • Year to date:
    • Site-wide: 38,413
  • Since beginning of last month:
    • Site-wide: 33,769

Body mass index and heart failure risk: a cohort study in 1.5 million individuals and Mendelian randomisation analysis

cardiovascular medicine more details view paper
  • Downloaded 305 times
  • Download rankings, all-time:
    • Site-wide: 84,143
    • In cardiovascular medicine: 134
  • Year to date:
    • Site-wide: 55,299
  • Since beginning of last month:
    • Site-wide: 70,231

Metabolic biomarkers for peripheral artery disease compared with coronary artery disease: Lipoprotein and metabolite profiling of 31,657 individuals from five prospective cohorts

epidemiology more details view paper
  • Downloaded 236 times
  • Download rankings, all-time:
    • Site-wide: 99,105
    • In epidemiology: 4,068
  • Year to date:
    • Site-wide: 78,969
  • Since beginning of last month:
    • Site-wide: 83,639

A phenome-wide multi-directional Mendelian randomization analysis of atrial fibrillation

epidemiology more details view paper
  • Downloaded 234 times
  • Download rankings, all-time:
    • Site-wide: 99,548
    • In epidemiology: 4,080
  • Year to date:
    • Site-wide: 32,738
  • Since beginning of last month:
    • Site-wide: 29,407

Evaluating the effects of cardiometabolic exposures on circulating proteins which may contribute to SARS-CoV-2 severity

epidemiology more details view paper
  • Downloaded 219 times
  • Download rankings, all-time:
    • Site-wide: 102,875
    • In epidemiology: 4,225
  • Year to date:
    • Site-wide: 49,692
  • Since beginning of last month:
    • Site-wide: 32,202

Circulating insulin-like growth factor-I, total and free testosterone concentrations and prostate cancer risk in 200,000 men in UK Biobank

epidemiology more details view paper
  • Downloaded 211 times
  • Download rankings, all-time:
    • Site-wide: 104,666
    • In epidemiology: 4,319
  • Year to date:
    • Site-wide: 85,258
  • Since beginning of last month:
    • Site-wide: 92,788

A proteome-wide genetic investigation identifies several SARS-CoV-2-exploited host targets of clinical relevance

pharmacology and therapeutics more details view paper
  • Downloaded 189 times
  • Download rankings, all-time:
    • Site-wide: 109,533
    • In pharmacology and therapeutics: 94
  • Year to date:
    • Site-wide: 11,710
  • Since beginning of last month:
    • Site-wide: 3,295

Obesity as a cause of kidney disease - insights from Mendelian randomisation studies

endocrinology more details view paper
  • Downloaded 143 times
  • Download rankings, all-time:
    • Site-wide: 119,243
    • In endocrinology: 102
  • Year to date:
    • Site-wide: 55,235
  • Since beginning of last month:
    • Site-wide: 54,500

Body muscle gain and markers of cardiovascular disease susceptibility in young adulthood: prospective cohort study

epidemiology more details view paper
  • Downloaded 141 times
  • Download rankings, all-time:
    • Site-wide: 119,493
    • In epidemiology: 4,890
  • Year to date:
    • Site-wide: 113,303
  • Since beginning of last month:
    • Site-wide: 101,415

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