Author: Ville Karhunen

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Preprints

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

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  • In genetics: 160
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  • Site-wide: 28,159
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  • Site-wide: 51,935

Polygenic risk scores applied to a single cohort reveal pleiotropy among hundreds of human phenotypes

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  • Site-wide: 12,594
  • In genetics: 478
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ACE inhibition and cardiometabolic risk factors, lung ACE2 and TMPRSS2 gene expression, and plasma ACE2 levels: a Mendelian randomization study

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  • Site-wide: 14,463
  • In genetic and genomic medicine: 87
• Year to date:
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  • Site-wide: 46,058

Genetic Associations with Subjective Well-Being Also Implicate Depression and Neuroticism

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  • Site-wide: 14,927
  • In genetics: 591
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  • Site-wide: 198,109

Genetic Association Study of Childhood Aggression across raters, instruments and age

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  • Site-wide: 22,931
  • In genomics: 2,000
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  • Site-wide: 46,155
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  • Site-wide: 120,746

Genome-wide association meta-analysis of childhood and adolescent internalising symptoms

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  • Site-wide: 37,465
  • In psychiatry and clinical psychology: 157
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Lower hemoglobin levels associate with lower body mass index and healthier metabolic profile

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  • Site-wide: 38,354
  • In epidemiology: 2,040
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  • Site-wide: 160,562
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  • Site-wide: 116,360

Genetically predicted serum urate, blood pressure and cardiovascular disease: an updated Mendelian randomization investigation

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  • Site-wide: 45,731
  • In cardiovascular medicine: 91
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Genetic architecture of early childhood growth phenotypes gives insights into their link with later obesity

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  • Site-wide: 54,726
  • In genomics: 3,977
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  • Site-wide: 74,980

Genetic study of circulating cytokines offers insight into the determinants, cascades and effects of systemic inflammation

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  • Site-wide: 69,929
  • In epidemiology: 3,211
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Exploring the causal effect of maternal pregnancy adiposity on offspring adiposity: Mendelian randomization using polygenic risk scores

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  • Site-wide: 77,071
  • In epidemiology: 3,534
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  • Site-wide: 104,606
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  • Site-wide: 44,471

A genome-wide association study of total child psychiatric problems scores

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  • Site-wide: 84,262
  • In psychiatry and clinical psychology: 409
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  • Site-wide: 128,474

DNA methylation links prenatal smoking exposure to later life health outcomes in offspring

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  • Site-wide: 84,961
  • In epidemiology: 3,744
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  • Site-wide: 147,519
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Risk factors mediating the effect of body-mass index and waist-to-hip ratio on cardiovascular outcomes: Mendelian randomization analysis

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  • In cardiovascular medicine: 228
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Variants at the ADAMTS13, BGALT5, SSBP2 and TKT Loci are associated with Post-term birth.

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  • Site-wide: 105,729
  • In genetics: 4,012
• Year to date:
  • Site-wide: 84,768
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Trans-ancestry genome-wide association study of gestational diabetes mellitus highlights genetic links with type 2 diabetes

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  • Site-wide: 117,641
  • In endocrinology: 127
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Maternal and fetal genetic contribution to gestational weight gain

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  • Site-wide: 145,384
  • In genetics: 5,433
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  • Site-wide: 144,831
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  • Site-wide: 198,264

Genetic fine-mapping from summary data using a non-local prior improves detection of multiple causal variants

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  • Site-wide: 204,802
  • In bioinformatics: None
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Re-evaluating the robustness of Mendelian randomisation to measurement error

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  • Site-wide: 210,026
  • In epidemiology: 8,163
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  • Site-wide: 109,143