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Author: Tom G Richardson

Rankings

  • All-time downloads: 24,358 (rank: 7,062 )
  • Categories:
    • bioinformatics: 1,065 (rank: 13,879 (tie) )
    • cardiovascular medicine: 1,176 (rank: 344 (tie) )
    • epidemiology: 4,133 (rank: 2,901 )
    • genetic and genomic medicine: 2,051 (rank: 815 )
    • genetics: 15,086 (rank: 943 )
    • genomics: 847 (rank: 25,484 (tie) )

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Preprints

Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases

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    • Site-wide: 2,981
    • In genetics: 112
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An atlas of polygenic risk score associations to highlight putative causal relationships across the human phenome

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    • Site-wide: 8,464
    • In genetics: 384
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    • Site-wide: 52,524
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A transcriptome-wide Mendelian randomization study to uncover tissue-dependent regulatory mechanisms across the human phenome

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  • Downloaded 1,625 times
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    • Site-wide: 10,602
    • In genetics: 505
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Systematic Mendelian randomization framework elucidates hundreds of genetic loci which may influence disease through changes in DNA methylation levels

genetics more details view paper
  • Downloaded 1,269 times
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    • Site-wide: 15,363
    • In genetics: 743
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Genome-wide association studies identify 137 loci for DNA methylation biomarkers of ageing

genetics more details view paper
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    • Site-wide: 15,862
    • In genetics: 772
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Causal epigenome-wide association study identifies CpG sites that influence cardiovascular disease risk

epidemiology more details view paper
  • Downloaded 1,218 times
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    • Site-wide: 16,299
    • In epidemiology: 1,039
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PhenoSpD: an integrated toolkit for phenotypic correlation estimation and multiple testing correction using GWAS summary statistics

bioinformatics more details view paper
  • Downloaded 1,065 times
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    • Site-wide: 19,883
    • In bioinformatics: 2,345
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Apolipoprotein B underlies the causal relationship of circulating blood lipids with coronary heart disease

cardiovascular medicine more details view paper
  • Downloaded 917 times
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    • Site-wide: 24,791
    • In cardiovascular medicine: 35
  • Year to date:
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Identification of loci where DNA methylation potentially mediates genetic risk of type 1 diabetes

genomics more details view paper
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    • In genomics: 2,552
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Genomic and phenomic insights from an atlas of genetic effects on DNA methylation

genetic and genomic medicine more details view paper
  • Downloaded 770 times
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    • Site-wide: 31,629
    • In genetic and genomic medicine: 103
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Integrating Mendelian randomization and multiple-trait colocalization to uncover cell-specific inflammatory drivers of autoimmune and atopic disease

genetics more details view paper
  • Downloaded 749 times
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    • Site-wide: 32,803
    • In genetics: 1,568
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    • Site-wide: 100,977
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    • Site-wide: 108,091

Can the impact of childhood adiposity on disease risk be reversed? A Mendelian randomization study

epidemiology more details view paper
  • Downloaded 739 times
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    • Site-wide: 33,415
    • In epidemiology: 1,685
  • Year to date:
    • Site-wide: 74,714
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    • Site-wide: 73,162

Using Y chromosomal haplogroups in genetic association studies and suggested implications

genetics more details view paper
  • Downloaded 719 times
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    • Site-wide: 34,712
    • In genetics: 1,654
  • Year to date:
    • Site-wide: 116,745
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    • Site-wide: 88,119

Investigating causality between liability to ADHD and substance use, and liability to substance use and ADHD risk, using Mendelian randomization

genetics more details view paper
  • Downloaded 705 times
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    • Site-wide: 35,703
    • In genetics: 1,695
  • Year to date:
    • Site-wide: 77,673
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    • Site-wide: 46,414

Prioritizing putative influential genes in early life cardiovascular disease susceptibility by applying tissue-specific Mendelian randomization

genetics more details view paper
  • Downloaded 678 times
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    • Site-wide: 37,622
    • In genetics: 1,771
  • Year to date:
    • Site-wide: 129,121
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    • Site-wide: 121,498

Genetic predictors of participation in optional components of UK Biobank

genetics more details view paper
  • Downloaded 645 times
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    • Site-wide: 40,179
    • In genetics: 1,885
  • Year to date:
    • Site-wide: 53,986
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    • Site-wide: 80,585

Conditioning on a collider may induce spurious associations: Do the results of Gale et al. (2017) support a protective effect of neuroticism in population sub-groups?

epidemiology more details view paper
  • Downloaded 537 times
  • Download rankings, all-time:
    • Site-wide: 50,315
    • In epidemiology: 2,275
  • Year to date:
    • Site-wide: 135,339
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    • Site-wide: 129,053

DNA methylation links prenatal smoking exposure to later life health outcomes in offspring

epidemiology more details view paper
  • Downloaded 520 times
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    • Site-wide: 52,343
    • In epidemiology: 2,342
  • Year to date:
    • Site-wide: 102,904
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    • Site-wide: 64,258

The role of gene expression on human sexual dimorphism: too early to call

genetics more details view paper
  • Downloaded 471 times
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    • Site-wide: 58,576
    • In genetics: 2,701
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    • Site-wide: 44,580
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    • Site-wide: 56,814

Leveraging brain cortex-derived molecular data to elucidate epigenetic and transcriptomic drivers of neurological function and disease

genetics more details view paper
  • Downloaded 458 times
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    • Site-wide: 60,360
    • In genetics: 2,764
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The use of negative control outcomes in Mendelian Randomisation to detect potential population stratification or selection bias.

genetics more details view paper
  • Downloaded 401 times
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    • Site-wide: 68,981
    • In genetics: 3,133
  • Year to date:
    • Site-wide: 55,914
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    • Site-wide: 55,673

A factorial Mendelian randomization study to systematically prioritize genetic targets for the treatment of cardiovascular disease

genetic and genomic medicine more details view paper
  • Downloaded 389 times
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    • Site-wide: 70,984
    • In genetic and genomic medicine: 253
  • Year to date:
    • Site-wide: 67,502
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    • Site-wide: 47,934

Effects of apolipoprotein B on the lifespan and risks of major disease including type 2 diabetes: a Mendelian randomization analysis using outcomes in first-degree relatives

epidemiology more details view paper
  • Downloaded 366 times
  • Download rankings, all-time:
    • Site-wide: 75,136
    • In epidemiology: 3,154
  • Year to date:
    • Site-wide: 45,801
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    • Site-wide: 62,521

Smoking, DNA methylation and lung function: a Mendelian randomization analysis to investigate causal relationships

genetic and genomic medicine more details view paper
  • Downloaded 357 times
  • Download rankings, all-time:
    • Site-wide: 76,875
    • In genetic and genomic medicine: 274
  • Year to date:
    • Site-wide: 99,703
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    • Site-wide: 74,455

DNA methylation mediates genetic liability to non-syndromic cleft lip/palate

genetics more details view paper
  • Downloaded 347 times
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    • Site-wide: 78,744
    • In genetics: 3,558
  • Year to date:
    • Site-wide: 118,689
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    • Site-wide: 88,303

An integrative multi-omics analysis of 16 autoimmune diseases and cancer outcomes highlights immune-cell regulatory mechanisms and shared genetic architecture

genetic and genomic medicine more details view paper
  • Downloaded 307 times
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    • Site-wide: 86,651
    • In genetic and genomic medicine: 332
  • Year to date:
    • Site-wide: 31,599
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    • Site-wide: 31,783

Evaluating the direct effects of childhood adiposity on adult systemic metabolism: A multivariable Mendelian randomization analysis

cardiovascular medicine more details view paper
  • Downloaded 259 times
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    • Site-wide: 97,096
    • In cardiovascular medicine: 185
  • Year to date:
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    • Site-wide: 52,630

A phenome-wide multi-directional Mendelian randomization analysis of atrial fibrillation

epidemiology more details view paper
  • Downloaded 247 times
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    • Site-wide: 99,810
    • In epidemiology: 4,102
  • Year to date:
    • Site-wide: 38,048
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    • Site-wide: 52,122

Evaluating the effects of cardiometabolic exposures on circulating proteins which may contribute to SARS-CoV-2 severity

epidemiology more details view paper
  • Downloaded 233 times
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    • Site-wide: 103,196
    • In epidemiology: 4,224
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Triangulating molecular evidence to prioritise candidate causal genes at established atopic dermatitis loci

genetic and genomic medicine more details view paper
  • Downloaded 228 times
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    • Site-wide: 104,209
    • In genetic and genomic medicine: 452
  • Year to date:
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Genetically-proxied therapeutic inhibition of antihypertensive drug targets and risk of common cancers

epidemiology more details view paper
  • Downloaded 173 times
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    • Site-wide: 116,832
    • In epidemiology: 4,815
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    • Site-wide: 18,690
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Disentangling the direct and indirect effects of childhood adiposity on type 1 diabetes and immune-associated diseases: a multivariable Mendelian randomization study

epidemiology more details view paper
  • Downloaded 100 times
  • Download rankings, all-time:
    • Site-wide: 131,519
    • In epidemiology: 5,334
  • Year to date:
    • Site-wide: 35,046
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    • Site-wide: 7,199

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