Author: the 23andMe Research Team

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Preprints

Genome-wide association analysis of lifetime cannabis use (N=184,765) identifies new risk loci, genetic overlap with mental health, and a causal influence of schizophrenia on cannabis use

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Phenome-wide association studies (PheWAS) across large "real-world data" population cohorts support drug target validation

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  • In genetics: 113 out of 4,628
• Year to date:
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  • Site-wide: 28,887 out of 89,572

Genome-wide association analyses of chronotype in 697,828 individuals provides new insights into circadian rhythms in humans and links to disease

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  • In genetics: 251 out of 4,628
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GWAS Meta-Analysis of Neuroticism (N=449,484) Identifies Novel Genetic Loci and Pathways

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  • In genetics: 267 out of 4,628
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Genome-wide analyses of self-reported empathy: correlations with autism, schizophrenia, and anorexia nervosa

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  • In genomics: 715 out of 5,703
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Human loss-of-function variants suggest that partial LRRK2 inhibition is a safe therapeutic strategy for Parkinson’s disease

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  • Site-wide: 9,980 out of 89,572

Large-scale genome-wide association meta-analysis of endometriosis reveals 13 novel loci and genetically-associated comorbidity with other pain conditions

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  • In genomics: 1,170 out of 5,703
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  • Site-wide: 13,288 out of 89,572

Genome-wide association study of delay discounting in 23,217 adult research participants of European ancestry

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  • In genetics: 662 out of 4,628
• Year to date:
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Genome-wide association studies of impulsive personality traits (BIS-11 and UPPSP) and drug experimentation in up to 22,861 adult research participants

• Downloaded 687 times
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  • In genetics: 1,297 out of 4,628
• Year to date:
  • Site-wide: 53,681 out of 89,572
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  • Site-wide: 76,730 out of 89,572

Genome-wide association study of social relationship satisfaction: significant loci and correlations with psychiatric conditions

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  • In genomics: 2,452 out of 5,703
• Year to date:
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  • Site-wide: 25,640 out of 89,572

Social and non-social autism symptom and trait domains are genetically dissociable

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Replication and characterization of CADM2 and MSRA genes on human behavior

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  • In genetics: 1,518 out of 4,628
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  • Site-wide: 86,962 out of 89,572

Genome-wide association studies on endometriosis and endometriosis-related infertility

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  • In genetics: 1,533 out of 4,628
• Year to date:
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The Latent Genetic Structure of Impulsivity and its Relation to Internalizing Psychopathology

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  • In genetics: 3,134 out of 4,628
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  • Site-wide: 30,522 out of 89,572

A Comprehensive Genome-wide and Phenome-wide Examination of BMI and Obesity in a Northern Nevadan Cohort

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  • In genetics: 3,716 out of 4,628
• Year to date:
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  • Site-wide: 46,858 out of 89,572