Author: David Hougaard

Downloads per author, site-wide

Preprints

Long-term storage has minor effects on biobanked neonatal dried blood spot metabolome

No download data for this paper yet.

The genetic and phenotypic correlates of neonatal Complement Component 3 and 4 protein concentrations with a focus on psychiatric and autoimmune disorders

No download data for this paper yet.

Discovery Of The First Genome-Wide Significant Risk Loci For ADHD

• Downloaded 12,665 times
• Download rankings, all-time:
  • Site-wide: 1,001
  • In genetics: 18
• Year to date:
  • Site-wide: 7,783
• Since beginning of last month:
  • Site-wide: 7,849

Large-scale exome sequencing study implicates both developmental and functional changes in the neurobiology of autism

• Downloaded 11,044 times
• Download rankings, all-time:
  • Site-wide: 1,206
  • In genetics: 24
• Year to date:
  • Site-wide: 13,710
• Since beginning of last month:
  • Site-wide: 14,904

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

• Downloaded 9,791 times
• Download rankings, all-time:
  • Site-wide: 1,376
  • In genetics: 27
• Year to date:
  • Site-wide: 39,559
• Since beginning of last month:
  • Site-wide: 24,495

Common risk variants identified in autism spectrum disorder

• Downloaded 9,268 times
• Download rankings, all-time:
  • Site-wide: 1,483
  • In genetics: 31
• Year to date:
  • Site-wide: 28,137
• Since beginning of last month:
  • Site-wide: 19,801

Exome sequencing identifies rare coding variants in 10 genes which confer substantial risk for schizophrenia

• Downloaded 8,928 times
• Download rankings, all-time:
  • Site-wide: 1,555
  • In genetic and genomic medicine: 9
• Year to date:
  • Site-wide: 694
• Since beginning of last month:
  • Site-wide: 758

Genomewide association study identifies 30 loci associated with bipolar disorder

• Downloaded 7,684 times
• Download rankings, all-time:
  • Site-wide: 1,902
  • In genetics: 42
• Year to date:
  • Site-wide: 60,791
• Since beginning of last month:
  • Site-wide: 36,968

Genome-wide association study of over 40,000 bipolar disorder cases provides new insights into the underlying biology

• Downloaded 3,654 times
• Download rankings, all-time:
  • Site-wide: 5,318
  • In psychiatry and clinical psychology: 20
• Year to date:
  • Site-wide: 11,693
• Since beginning of last month:
  • Site-wide: 16,884

Sex-Dependent Shared and Non-Shared Genetic Architecture Across Mood and Psychotic Disorders

• Downloaded 2,855 times
• Download rankings, all-time:
  • Site-wide: 7,606
  • In genetics: 281
• Year to date:
  • Site-wide: 4,265
• Since beginning of last month:
  • Site-wide: 20,350

Quantifying the impact of rare and ultra-rare coding variation across the phenotypic spectrum

• Downloaded 2,851 times
• Download rankings, all-time:
  • Site-wide: 7,620
  • In genetics: 280
• Year to date:
  • Site-wide: 95,818
• Since beginning of last month:
  • Site-wide: 32,069

Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders

• Downloaded 2,527 times
• Download rankings, all-time:
  • Site-wide: 9,111
  • In genetics: 346
• Year to date:
  • Site-wide: 114,227
• Since beginning of last month:
  • Site-wide: 79,804

ASD and ADHD have a similar burden of rare protein-truncating variants

• Downloaded 2,073 times
• Download rankings, all-time:
  • Site-wide: 12,319
  • In genetics: 455
• Year to date:
  • Site-wide: 72,655
• Since beginning of last month:
  • Site-wide: 29,978

Genome-wide association study implicates CHRNA2 in cannabis use disorder

• Downloaded 1,998 times
• Download rankings, all-time:
  • Site-wide: 13,008
  • In genomics: 1,172
• Year to date:
  • Site-wide: 78,582
• Since beginning of last month:
  • Site-wide: 67,956

A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

• Downloaded 1,956 times
• Download rankings, all-time:
  • Site-wide: 13,451
  • In genetics: 504
• Year to date:
  • Site-wide: 166,173
• Since beginning of last month:
  • Site-wide: 203,583

The female protective effect against autism spectrum disorder

• Downloaded 1,860 times
• Download rankings, all-time:
  • Site-wide: 14,500
  • In genetic and genomic medicine: 92
• Year to date:
  • Site-wide: 4,810
• Since beginning of last month:
  • Site-wide: 15,851

Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains

• Downloaded 1,759 times
• Download rankings, all-time:
  • Site-wide: 15,817
  • In psychiatry and clinical psychology: 103
• Year to date:
  • Site-wide: 1,388
• Since beginning of last month:
  • Site-wide: 974

Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population

• Downloaded 1,745 times
• Download rankings, all-time:
  • Site-wide: 16,003
  • In genetics: 622
• Year to date:
  • Site-wide: 181,300
• Since beginning of last month:
  • Site-wide: 165,707

Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

• Downloaded 1,606 times
• Download rankings, all-time:
  • Site-wide: 18,203
  • In genomics: 1,618
• Year to date:
  • Site-wide: 109,237
• Since beginning of last month:
  • Site-wide: 91,987

Genome-wide association study of school grades identifies a genetic overlap between language ability, psychopathology and creativity

• Downloaded 1,585 times
• Download rankings, all-time:
  • Site-wide: 18,575
  • In genomics: 1,806
• Year to date:
  • Site-wide: 23,658
• Since beginning of last month:
  • Site-wide: 7,151

Identification of shared and differentiating genetic risk for autism spectrum disorder, attention deficit hyperactivity disorder and case subgroups.

• Downloaded 1,583 times
• Download rankings, all-time:
  • Site-wide: 18,613
  • In psychiatry and clinical psychology: 192
• Year to date:
  • Site-wide: 4,159
• Since beginning of last month:
  • Site-wide: 283

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

• Downloaded 1,520 times
• Download rankings, all-time:
  • Site-wide: 19,833
  • In genetics: 795
• Year to date:
  • Site-wide: 159,251
• Since beginning of last month:
  • Site-wide: 166,823

A genetic investigation of sex bias in the prevalence of attention deficit hyperactivity disorder

• Downloaded 1,511 times
• Download rankings, all-time:
  • Site-wide: 20,041
  • In genetics: 791
• Year to date:
  • Site-wide: 165,956
• Since beginning of last month:
  • Site-wide: 196,362

Genome-wide Association Study of Anxiety and Stress-related Disorders in the iPSYCH Cohort

• Downloaded 1,472 times
• Download rankings, all-time:
  • Site-wide: 20,922
  • In genetics: 842
• Year to date:
  • Site-wide: 110,905
• Since beginning of last month:
  • Site-wide: 66,941

Mitochondrial DNA SNPs associated with Schizophrenia exhibit Highly Variable Inter-allelic Haplogroup Affiliation and Nuclear Genogeographic Affinity: Bi-Genomic Linkage Disequilibrium raises Major Concerns for Link to Disease

• Downloaded 1,315 times
• Download rankings, all-time:
  • Site-wide: 25,028
  • In genomics: 2,117
• Year to date:
  • Site-wide: 110,871
• Since beginning of last month:
  • Site-wide: 69,233

The genetic architecture of sporadic and recurrent miscarriage

• Downloaded 1,307 times
• Download rankings, all-time:
  • Site-wide: 25,292
  • In genetics: 993
• Year to date:
  • Site-wide: 131,738
• Since beginning of last month:
  • Site-wide: 78,927

A genome-wide association study for shared risk across major psychiatric disorders in a nation-wide birth cohort implicates fetal neurodevelopment as a key mediator

• Downloaded 1,286 times
• Download rankings, all-time:
  • Site-wide: 25,934
  • In genetics: 1,015
• Year to date:
  • Site-wide: 169,016
• Since beginning of last month:
  • Site-wide: 92,120

Complex spatio-temporal distribution and genogeographic affinity of mitochondrial DNA haplogroups in 24,216 Danes

• Downloaded 1,102 times
• Download rankings, all-time:
  • Site-wide: 32,992
  • In genomics: 2,708
• Year to date:
  • Site-wide: 107,431
• Since beginning of last month:
  • Site-wide: 40,624

Untargeted metabolomic study of autism in newborn screening samples: a pilot study

• Downloaded 1,074 times
• Download rankings, all-time:
  • Site-wide: 34,326
  • In psychiatry and clinical psychology: 143
• Year to date:
  • Site-wide: 45,385
• Since beginning of last month:
  • Site-wide: 27,531

Genome-wide association study identifies new locus associated with OCD

• Downloaded 1,027 times
• Download rankings, all-time:
  • Site-wide: 36,733
  • In psychiatry and clinical psychology: 188
• Year to date:
  • Site-wide: 8,891
• Since beginning of last month:
  • Site-wide: 7,690

Gestational-age-dependent development of the neonatal metabolome

• Downloaded 884 times
• Download rankings, all-time:
  • Site-wide: 46,285
  • In pediatrics: 92
• Year to date:
  • Site-wide: 44,499
• Since beginning of last month:
  • Site-wide: 36,572

The iPSYCH2012 case-cohort sample: New directions for unravelling genetic and environmental architectures of severe mental disorders

• Downloaded 843 times
• Download rankings, all-time:
  • Site-wide: 49,692
  • In genetics: 1,903
• Year to date:
  • Site-wide: 199,590
• Since beginning of last month:
  • Site-wide: 129,437

Multi-PGS enhances polygenic prediction: weighting 937 polygenic scores

• Downloaded 761 times
• Download rankings, all-time:
  • Site-wide: 57,837
  • In genetic and genomic medicine: None
• Year to date:
  • Site-wide: 5,273
• Since beginning of last month:
  • Site-wide: 1,789

Meta-analysis of Scandinavian Schizophrenia Exomes

• Downloaded 752 times
• Download rankings, all-time:
  • Site-wide: 58,803
  • In genetics: 2,364
• Year to date:
  • Site-wide: 78,034
• Since beginning of last month:
  • Site-wide: 46,969

Identification of risk variants and characterization of the polygenic architecture of disruptive behavior disorders in the context of ADHD

• Downloaded 751 times
• Download rankings, all-time:
  • Site-wide: 58,954
  • In genomics: 4,097
• Year to date:
  • Site-wide: 137,574
• Since beginning of last month:
  • Site-wide: 160,584

The iPSYCH2015 Case-Cohort sample: updated directions for unravelling genetic and environmental architectures of severe mental disorders

• Downloaded 729 times
• Download rankings, all-time:
  • Site-wide: 61,531
  • In epidemiology: 3,127
• Year to date:
  • Site-wide: 32,948
• Since beginning of last month:
  • Site-wide: 21,278

Statistical and functional convergence of common and rare variant risk for autism spectrum disorders at chromosome 16p

• Downloaded 636 times
• Download rankings, all-time:
  • Site-wide: 74,558
  • In psychiatry and clinical psychology: 403
• Year to date:
  • Site-wide: 7,162
• Since beginning of last month:
  • Site-wide: 28,118

Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 are associated with gestational duration

• Downloaded 621 times
• Download rankings, all-time:
  • Site-wide: 76,851
  • In genetics: 2,893
• Year to date:
  • Site-wide: 194,069
• Since beginning of last month:
  • Site-wide: 150,132

Genetic factors underlying the bidirectional relationship between autoimmune and mental disorders – findings from a Danish population-based study

• Downloaded 614 times
• Download rankings, all-time:
  • Site-wide: 77,982
  • In bioinformatics: 7,413
• Year to date:
  • Site-wide: 69,608
• Since beginning of last month:
  • Site-wide: 44,752

Accounting for age-of-onset and family history improves power in genome-wide association studies

• Downloaded 589 times
• Download rankings, all-time:
  • Site-wide: 82,101
  • In bioinformatics: 7,356
• Year to date:
  • Site-wide: 80,244
• Since beginning of last month:
  • Site-wide: 157,584

Identification of 64 new risk loci for major depression, refinement of the genetic architecture and risk prediction of recurrence and comorbidities

• Downloaded 520 times
• Download rankings, all-time:
  • Site-wide: 95,557
  • In genetic and genomic medicine: None
• Year to date:
  • Site-wide: 9,896
• Since beginning of last month:
  • Site-wide: 11,077

Polygenic prediction of school performance in children with and without psychiatric disorders

• Downloaded 506 times
• Download rankings, all-time:
  • Site-wide: 98,489
  • In genetics: 3,753
• Year to date:
  • Site-wide: 148,538
• Since beginning of last month:
  • Site-wide: 139,588

Differences in the genetic architecture of common and rare variants in childhood, persistent and late-diagnosed attention deficit hyperactivity disorder

• Downloaded 505 times
• Download rankings, all-time:
  • Site-wide: 98,879
  • In psychiatry and clinical psychology: 647
• Year to date:
  • Site-wide: 38,035
• Since beginning of last month:
  • Site-wide: 15,952

Genome-wide association study of febrile seizures identifies seven new loci implicating fever response and neuronal excitability genes

• Downloaded 472 times
• Download rankings, all-time:
  • Site-wide: 106,413
  • In genetic and genomic medicine: 658
• Year to date:
  • Site-wide: 90,135
• Since beginning of last month:
  • Site-wide: 144,987

Polygenic profiles define aspects of clinical heterogeneity in ADHD

• Downloaded 469 times
• Download rankings, all-time:
  • Site-wide: 107,287
  • In psychiatry and clinical psychology: 589
• Year to date:
  • Site-wide: 50,153
• Since beginning of last month:
  • Site-wide: 50,685

Preterm birth, stillbirth, and early neonatal mortality during the Danish COVID-19 lockdown

• Downloaded 405 times
• Download rankings, all-time:
  • Site-wide: 123,254
  • In pediatrics: 227
• Year to date:
  • Site-wide: 111,734
• Since beginning of last month:
  • Site-wide: 159,407

ADuLT: An efficient and robust time-to-event GWAS

• Downloaded 400 times
• Download rankings, all-time:
  • Site-wide: 124,735
  • In genetic and genomic medicine: None
• Year to date:
  • Site-wide: 15,496
• Since beginning of last month:
  • Site-wide: 10,592

Comprehensive genome-wide association study of different forms of hernia identifies more than 80 associated loci

• Downloaded 367 times
• Download rankings, all-time:
  • Site-wide: 134,331
  • In genetic and genomic medicine: 898
• Year to date:
  • Site-wide: 68,559
• Since beginning of last month:
  • Site-wide: 82,405

Polygenic heterogeneity across obsessive-compulsive disorder subgroups defined by a comorbid diagnosis

• Downloaded 265 times
• Download rankings, all-time:
  • Site-wide: 164,523
  • In psychiatry and clinical psychology: 990
• Year to date:
  • Site-wide: 123,468
• Since beginning of last month:
  • Site-wide: 155,475

Interplay of ADHD polygenic liability with birth-related, somatic and psychosocial factors in ADHD - a nationwide study

• Downloaded 248 times
• Download rankings, all-time:
  • Site-wide: 169,402
  • In psychiatry and clinical psychology: 1,089
• Year to date:
  • Site-wide: 84,911
• Since beginning of last month:
  • Site-wide: 63,686

Mendelian randomization study of spermine oxidase and cancer risk

• Downloaded 213 times
• Download rankings, all-time:
  • Site-wide: 178,447
  • In genetic and genomic medicine: 1,249
• Year to date:
  • Site-wide: 175,377
• Since beginning of last month:
  • Site-wide: 191,164

Genome-wide by environment interaction study of stressful life events and hospital-treated depression in the iPSYCH2012 sample

• Downloaded 202 times
• Download rankings, all-time:
  • Site-wide: 181,188
  • In genetic and genomic medicine: 1,277
• Year to date:
  • Site-wide: 113,779
• Since beginning of last month:
  • Site-wide: 156,125

Genetic correlates of vitamin D-binding protein and 25 hydroxyvitamin D in neonatal dried blood spots

• Downloaded 196 times
• Download rankings, all-time:
  • Site-wide: 182,549
  • In genetic and genomic medicine: 1,347
• Year to date:
  • Site-wide: 45,855
• Since beginning of last month:
  • Site-wide: 77,797

The genetic background of hydrocephalus in a population-based cohort: implication of ciliary involvement

• Downloaded 159 times
• Download rankings, all-time:
  • Site-wide: 190,479
  • In genetic and genomic medicine: 1,435
• Year to date:
  • Site-wide: 60,048
• Since beginning of last month:
  • Site-wide: 38,115

THE IMPACT OF THE COVID-19 LOCKDOWN ON BIRTH WEIGHT AMONG SINGLETON TERM BIRTHS IN DENMARK

• Downloaded 107 times
• Download rankings, all-time:
  • Site-wide: 199,631
  • In pediatrics: None
• Year to date:
  • Site-wide: 88,127
• Since beginning of last month:
  • Site-wide: 4,597

Mitochondrial DNA haplogroup variation in hydrocephalus

• Downloaded 83 times
• Download rankings, all-time:
  • Site-wide: 203,343
  • In genetic and genomic medicine: None
• Year to date:
  • Site-wide: 110,204
• Since beginning of last month:
  • Site-wide: 105,716

Brief report: Preterm birth rates among twins during the Danish COVID-19 lockdown and mitigation period.

• Downloaded 64 times
• Download rankings, all-time:
  • Site-wide: 206,042
  • In pediatrics: None
• Year to date:
  • Site-wide: 137,197
• Since beginning of last month:
  • Site-wide: 145,386