Author: Ching-Ti Liu

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Preprints

Recovery of trait heritability from whole genome sequence data

• Downloaded 12,829 times
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  • Site-wide: 678
  • In genetics: 15
• Year to date:
  • Site-wide: 1,413
• Since beginning of last month:
  • Site-wide: 4,125

Fine-mapping of an expanded set of type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

• Downloaded 3,277 times
• Download rankings, all-time:
  • Site-wide: 4,265
  • In genomics: 440
• Year to date:
  • Site-wide: 83,079
• Since beginning of last month:
  • Site-wide: 58,254

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

• Downloaded 1,881 times
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  • Site-wide: 9,587
  • In genetics: 417
• Year to date:
  • Site-wide: 100,017
• Since beginning of last month:
  • Site-wide: 61,447

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

• Downloaded 1,726 times
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  • Site-wide: 10,867
  • In genetics: 481
• Year to date:
  • Site-wide: 61,148
• Since beginning of last month:
  • Site-wide: None

A trans-ancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation.

• Downloaded 1,716 times
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  • Site-wide: 10,975
  • In genetic and genomic medicine: 45
• Year to date:
  • Site-wide: 1,499
• Since beginning of last month:
  • Site-wide: 2,853

Genetic discovery and translational decision support from exome sequencing of 20,791 type 2 diabetes cases and 24,440 controls from five ancestries

• Downloaded 1,690 times
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  • Site-wide: 11,204
  • In genetics: 499
• Year to date:
  • Site-wide: 85,582
• Since beginning of last month:
  • Site-wide: 22,864

Trans-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

• Downloaded 1,440 times
• Download rankings, all-time:
  • Site-wide: 14,198
  • In genetic and genomic medicine: 60
• Year to date:
  • Site-wide: 6,285
• Since beginning of last month:
  • Site-wide: 13,265

The Trans-Ancestral Genomic Architecture of Glycaemic Traits

• Downloaded 1,074 times
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  • Site-wide: 22,003
  • In genetics: 1,004
• Year to date:
  • Site-wide: 10,170
• Since beginning of last month:
  • Site-wide: 44,082

Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation

• Downloaded 993 times
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  • Site-wide: 24,645
  • In genetics: 1,126
• Year to date:
  • Site-wide: 23,411
• Since beginning of last month:
  • Site-wide: 90,580

Multi-ancestry analysis of gene-sleep interactions in 126,926 individuals identifies multiple novel blood lipid loci that contribute to our understanding of sleep-associated adverse blood lipid profile

• Downloaded 518 times
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  • Site-wide: 58,728
  • In genomics: 4,325
• Year to date:
  • Site-wide: 141,409
• Since beginning of last month:
  • Site-wide: None

Methylome-Wide Association Study Of Central Adiposity Implicates Genes Involved In Immune And Endocrine Systems

• Downloaded 494 times
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  • Site-wide: 61,924
  • In genomics: 4,475
• Year to date:
  • Site-wide: 54,634
• Since beginning of last month:
  • Site-wide: 58,911

Rare Non-coding Variation Identified by Large Scale Whole Genome Sequencing Reveals Unexplained Heritability of Type 2 Diabetes: Trans-Omics for Precision Medicine (TOPMed) Program

• Downloaded 451 times
• Download rankings, all-time:
  • Site-wide: 68,333
  • In genetic and genomic medicine: 277
• Year to date:
  • Site-wide: 24,109
• Since beginning of last month:
  • Site-wide: 26,053

Impact of rare and common genetic variants on diabetes diagnosis by hemoglobin A1c in multi-ancestry cohorts: The Trans-Omics for Precision Medicine Program.

• Downloaded 412 times
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  • Site-wide: 74,726
  • In genetics: 3,272
• Year to date:
  • Site-wide: 99,947
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  • Site-wide: 56,001

A unified method for rare variant analysis of gene-environment interactions

• Downloaded 365 times
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  • Site-wide: 83,632
  • In genetics: 3,656
• Year to date:
  • Site-wide: 107,019
• Since beginning of last month:
  • Site-wide: 64,754

Efficient gene-environment interaction tests for large biobank-scale sequencing studies

• Downloaded 338 times
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  • Site-wide: 89,106
  • In genetics: 3,864
• Year to date:
  • Site-wide: 68,645
• Since beginning of last month:
  • Site-wide: 66,447

Role of Rare and Low Frequency Variants in Gene-Alcohol Interactions on Plasma Lipid Levels

• Downloaded 324 times
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  • Site-wide: 92,260
  • In epidemiology: 3,870
• Year to date:
  • Site-wide: 103,266
• Since beginning of last month:
  • Site-wide: None

Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure

• Downloaded 289 times
• Download rankings, all-time:
  • Site-wide: 100,202
  • In genomics: 6,065
• Year to date:
  • Site-wide: 63,162
• Since beginning of last month:
  • Site-wide: 23,775

Whole Genome Sequence Association Analysis of Fasting Glucose and Fasting Insulin Levels in Diverse Cohorts from the NHLBI TOPMed Program

• Downloaded 281 times
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  • Site-wide: 101,944
  • In genetic and genomic medicine: 478
• Year to date:
  • Site-wide: 19,390
• Since beginning of last month:
  • Site-wide: None

Metabolomics insights into osteoporosis through association with bone mineral density

• Downloaded 133 times
• Download rankings, all-time:
  • Site-wide: 137,287
  • In epidemiology: 5,663
• Year to date:
  • Site-wide: 48,139
• Since beginning of last month:
  • Site-wide: 112,992

Lifestyle Risk Score for aggregating multiple lifestyle factors: Handling missingness of individual lifestyle components in meta-analysis of gene-by-lifestyle interactions

• Downloaded 127 times
• Download rankings, all-time:
  • Site-wide: 138,703
  • In genetics: 5,578
• Year to date:
  • Site-wide: 133,393
• Since beginning of last month:
  • Site-wide: 70,113