Author: Ching-Ti Liu

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Preprints

Recovery of trait heritability from whole genome sequence data

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  • Site-wide: 623
  • In genetics: 17
• Year to date:
  • Site-wide: 1,907
• Since beginning of last month:
  • Site-wide: 1,423

Fine-mapping of an expanded set of type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

• Downloaded 3,223 times
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  • Site-wide: 3,504
  • In genomics: 398
• Year to date:
  • Site-wide: 69,480
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  • Site-wide: 51,373

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

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  • Site-wide: 7,969
  • In genetics: 387
• Year to date:
  • Site-wide: None
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  • Site-wide: None

Genetic discovery and translational decision support from exome sequencing of 20,791 type 2 diabetes cases and 24,440 controls from five ancestries

• Downloaded 1,640 times
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  • Site-wide: 9,419
  • In genetics: 461
• Year to date:
  • Site-wide: 65,230
• Since beginning of last month:
  • Site-wide: 63,704

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

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  • Site-wide: 9,448
  • In genetics: 464
• Year to date:
  • Site-wide: 80,032
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  • Site-wide: 77,425

Trans-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

• Downloaded 980 times
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  • Site-wide: 20,279
  • In genetic and genomic medicine: 61
• Year to date:
  • Site-wide: 6,816
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  • Site-wide: 7,252

A genome-wide association study for nonalcoholic fatty liver disease identifies novel genetic loci and trait-relevant candidate genes in the Million Veteran Program.

• Downloaded 807 times
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  • Site-wide: 26,694
  • In genetic and genomic medicine: 77
• Year to date:
  • Site-wide: 662
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  • Site-wide: 2,085

Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation

• Downloaded 798 times
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  • Site-wide: 27,100
  • In genetics: 1,350
• Year to date:
  • Site-wide: 26,541
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  • Site-wide: 45,487

The Trans-Ancestral Genomic Architecture of Glycaemic Traits

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  • Site-wide: 31,900
  • In genetics: 1,583
• Year to date:
  • Site-wide: 15,168
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  • Site-wide: 11,650

Multi-ancestry analysis of gene-sleep interactions in 126,926 individuals identifies multiple novel blood lipid loci that contribute to our understanding of sleep-associated adverse blood lipid profile

• Downloaded 501 times
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  • Site-wide: 49,640
  • In genomics: 3,928
• Year to date:
  • Site-wide: 109,166
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  • Site-wide: 98,130

Methylome-Wide Association Study Of Central Adiposity Implicates Genes Involved In Immune And Endocrine Systems

• Downloaded 391 times
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  • Site-wide: 64,428
  • In genomics: 4,641
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  • Site-wide: 82,159
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  • Site-wide: 64,336

Impact of rare and common genetic variants on diabetes diagnosis by hemoglobin A1c in multi-ancestry cohorts: The Trans-Omics for Precision Medicine Program.

• Downloaded 374 times
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  • Site-wide: 67,205
  • In genetics: 3,141
• Year to date:
  • Site-wide: 68,774
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  • Site-wide: 84,554

A unified method for rare variant analysis of gene-environment interactions

• Downloaded 334 times
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  • Site-wide: 74,145
  • In genetics: 3,449
• Year to date:
  • Site-wide: 63,972
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  • Site-wide: 39,029

Role of Rare and Low Frequency Variants in Gene-Alcohol Interactions on Plasma Lipid Levels

• Downloaded 290 times
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  • Site-wide: 82,544
  • In epidemiology: 3,379
• Year to date:
  • Site-wide: 63,929
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  • Site-wide: 51,613

Rare Non-coding Variation Identified by Large Scale Whole Genome Sequencing Reveals Unexplained Heritability of Type 2 Diabetes: Trans-Omics for Precision Medicine (TOPMed) Program

• Downloaded 271 times
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  • Site-wide: 86,658
  • In genetic and genomic medicine: 291
• Year to date:
  • Site-wide: 21,874
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  • Site-wide: 20,003

Efficient gene-environment interaction tests for large biobank-scale sequencing studies

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  • Site-wide: 88,674
  • In genetics: 4,052
• Year to date:
  • Site-wide: 81,035
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  • Site-wide: None

Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure

• Downloaded 199 times
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  • Site-wide: 102,161
  • In genomics: 6,025
• Year to date:
  • Site-wide: 101,479
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  • Site-wide: 103,362

Whole Genome Sequence Association Analysis of Fasting Glucose and Fasting Insulin Levels in Diverse Cohorts from the NHLBI TOPMed Program

• Downloaded 148 times
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  • Site-wide: 112,579
  • In genetic and genomic medicine: 489
• Year to date:
  • Site-wide: 7,117
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  • Site-wide: 13,954

Lifestyle Risk Score for aggregating multiple lifestyle factors: Handling missingness of individual lifestyle components in meta-analysis of gene-by-lifestyle interactions

• Downloaded 107 times
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  • Site-wide: 120,107
  • In genetics: 5,154
• Year to date:
  • Site-wide: 93,191
• Since beginning of last month:
  • Site-wide: 60,342

Metabolomics insights into osteoporosis through association with bone mineral density

• Downloaded 35 times
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  • Site-wide: 127,708
  • In epidemiology: 5,130
• Year to date:
  • Site-wide: 36,587
• Since beginning of last month:
  • Site-wide: 74,708