Author: Todd Lencz

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Preprints

Evidence for Cytokine Dysregulation in Schizophrenia Spectrum Disorders: A Comparison of Cerebrospinal Fluid and Blood Samples

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GWAS meta-analysis (N=279,930) identifies new genes and functional links to intelligence

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Genome-wide data from medieval German Jews show that the Ashkenazi founder event pre-dated the 14th century

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Screening human embryos for polygenic traits has limited utility

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Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

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Sex-Dependent Shared and Non-Shared Genetic Architecture Across Mood and Psychotic Disorders

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The Time and Place of European Admixture in the Ashkenazi Jewish History

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Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

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Novel ultra-Rare exonic variants identified in a founder population implicate cadherins in schizophrenia

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Utility of polygenic embryo screening for disease depends on the selection strategy

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Whole exome sequencing in the UK Biobank reveals risk gene SLC2A1 and biological insights for major depressive disorder

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Large-Scale Evaluation of the Positive and Negative Syndrome Scale (PANSS) Symptom Architecture in Schizophrenia

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The impact of rare protein coding genetic variation on adult cognitive function

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Rare schizophrenia risk variant burden is conserved in diverse human populations

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Striatal functional connectivity in psychosis relapse: A comparison between antipsychotic adherent and non-adherent patients at the time of relapse

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Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways

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Large-Scale cognitive GWAS Meta-analysis Reveals Tissue-Specific Neural Expression and Potential Nootopic Drug Targets

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Identifying Nootropic Drug Targets via Large-Scale Cognitive GWAS and Transcriptomics

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Schizophrenia Polygenic Risk Score and 20-Year Course of Illness in Psychotic Disorders

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Shared Polygenicity detection using Elastic Nets: SHARPEN

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High-depth whole genome sequencing of a large population-specific reference panel: Enhancing sensitivity, accuracy, and imputation

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Elucidating the Joint Genetic Architecture of Mood Disorder and Schizophrenia

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Leveraging correlations between polygenic risk score predictors to detect heterogeneity in GWAS cohorts

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Dissecting Biological Pathways of Psychopathology using Cognitive Genomics

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Striatal volume and functional connectivity predict weight gain in early-phase psychosis

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Frontal lobe fALFF measured from resting-state fMRI at baseline predicts acute treatment response in first episode psychosis

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