Author: Frank Dudbridge

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Preprints

Genomic risk prediction of coronary artery disease in nearly 500,000 adults: implications for early screening and primary prevention

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  • Site-wide: 2,645
  • In genetics: 101
• Year to date:
  • Site-wide: 42,998
• Since beginning of last month:
  • Site-wide: 56,130

A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

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  • Site-wide: 8,861
  • In genetics: 416
• Year to date:
  • Site-wide: 49,467
• Since beginning of last month:
  • Site-wide: 60,856

New genetic signals for lung function highlight pathways and pleiotropy, and chronic obstructive pulmonary disease associations across multiple ancestries

• Downloaded 1,586 times
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  • Site-wide: 10,598
  • In genomics: 1,147
• Year to date:
  • Site-wide: 65,478
• Since beginning of last month:
  • Site-wide: 65,125

Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

• Downloaded 1,458 times
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  • Site-wide: 11,966
  • In genomics: 1,299
• Year to date:
  • Site-wide: 75,279
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  • Site-wide: 76,635

Causal Analyses, Statistical Efficiency And Phenotypic Precision Through Recall-By-Genotype Study Design

• Downloaded 1,132 times
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  • Site-wide: 17,555
  • In genetics: 855
• Year to date:
  • Site-wide: 51,900
• Since beginning of last month:
  • Site-wide: 77,917

Use of polygenic risk scores and other molecular markers to enhance cardiovascular risk prediction: Prospective cohort study and modelling analysis

• Downloaded 1,082 times
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  • Site-wide: 18,776
  • In genomics: 1,899
• Year to date:
  • Site-wide: 47,103
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  • Site-wide: 43,872

Are Your Covariates Under Control? How Normalization Can Re-introduce Covariate Effects

• Downloaded 807 times
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  • Site-wide: 28,543
  • In epidemiology: 1,508
• Year to date:
  • Site-wide: 65,873
• Since beginning of last month:
  • Site-wide: 78,323

Adjustment for index event bias in genome-wide association studies of subsequent events

• Downloaded 806 times
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  • Site-wide: 28,627
  • In epidemiology: 1,513
• Year to date:
  • Site-wide: 131,962
• Since beginning of last month:
  • Site-wide: 132,785

Genetic sensitivity analysis: adjusting for genetic confounding in epidemiological associations

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  • Site-wide: 35,405
  • In genetics: 1,697
• Year to date:
  • Site-wide: 16,671
• Since beginning of last month:
  • Site-wide: 20,611

Slope-Hunter: A robust method for index-event bias correction in genome-wide association studies of subsequent traits

• Downloaded 667 times
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  • Site-wide: 37,175
  • In genetics: 1,772
• Year to date:
  • Site-wide: 23,910
• Since beginning of last month:
  • Site-wide: 35,132

Are there causal relationships between ADHD and BMI? Evidence from multiple genetically informed designs

• Downloaded 466 times
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  • Site-wide: 57,369
  • In psychiatry and clinical psychology: 175
• Year to date:
  • Site-wide: 51,704
• Since beginning of last month:
  • Site-wide: 48,562

Association of polygenic risk scores for coronary artery disease with subsequent events amongst established cases

• Downloaded 445 times
• Download rankings, all-time:
  • Site-wide: 60,216
  • In genetic and genomic medicine: 192
• Year to date:
  • Site-wide: 63,506
• Since beginning of last month:
  • Site-wide: 62,893

Genome-wide analysis of adolescent psychotic experiences shows genetic overlap with psychiatric disorders

• Downloaded 424 times
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  • Site-wide: 63,194
  • In genetics: 2,933
• Year to date:
  • Site-wide: 104,283
• Since beginning of last month:
  • Site-wide: 87,644

Genetic overlap and causal associations between smoking behaviours and psychiatric traits and disorders in adolescents and adults

• Downloaded 408 times
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  • Site-wide: 65,722
  • In genetic and genomic medicine: 220
• Year to date:
  • Site-wide: 62,520
• Since beginning of last month:
  • Site-wide: 67,252

Genetic nurture effects on education: a systematic review and meta-analysis

• Downloaded 405 times
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  • Site-wide: 66,224
  • In genetics: 3,054
• Year to date:
  • Site-wide: 4,182
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  • Site-wide: 13,866

Exploiting collider bias to apply two-sample summary data Mendelian randomization methods to one-sample individual level data

• Downloaded 311 times
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  • Site-wide: 83,318
  • In epidemiology: 3,432
• Year to date:
  • Site-wide: 19,035
• Since beginning of last month:
  • Site-wide: 21,932

Genetic overlap between psychotic experiences in the community across age and with psychiatric disorders

• Downloaded 241 times
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  • Site-wide: 98,263
  • In genomics: 5,924
• Year to date:
  • Site-wide: 134,940
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  • Site-wide: 134,604

Proportion of idiopathic pulmonary fibrosis risk explained by known genetic loci

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  • Site-wide: 106,384
  • In epidemiology: 4,387
• Year to date:
  • Site-wide: 42,877
• Since beginning of last month:
  • Site-wide: 59,878

Mendelian randomisation analyses of eosinophils and other blood cell types in relation to lung function and disease.

• Downloaded 147 times
• Download rankings, all-time:
  • Site-wide: 118,854
  • In epidemiology: 4,869
• Year to date:
  • Site-wide: 67,983
• Since beginning of last month:
  • Site-wide: 55,379

Relative Contributions of Family History and a Polygenic Risk Score on COPD and Related Outcomes: COPDGene and ECLIPSE studies

• Downloaded 145 times
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  • Site-wide: 119,437
  • In respiratory medicine: 221
• Year to date:
  • Site-wide: 106,350
• Since beginning of last month:
  • Site-wide: 110,929

Smoking Interaction with a Polygenic Risk Score for Reduced Lung Function

• Downloaded 83 times
• Download rankings, all-time:
  • Site-wide: 130,565
  • In genetic and genomic medicine: 646
• Year to date:
  • Site-wide: 33,039
• Since beginning of last month:
  • Site-wide: 11,692