Author: Richa Saxena

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Preprints

Selection into shift work is influenced by educational attainment and body mass index: A Mendelian randomization study

• Downloaded 62,221 times
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  • Site-wide: 142
  • In epidemiology: 32
• Year to date:
  • Site-wide: 42,647
• Since beginning of last month:
  • Site-wide: 140,975

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

• Downloaded 9,791 times
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  • Site-wide: 1,376
  • In genetics: 27
• Year to date:
  • Site-wide: 39,559
• Since beginning of last month:
  • Site-wide: 24,495

A Saturated Map of Common Genetic Variants Associated with Human Height from 5.4 Million Individuals of Diverse Ancestries

• Downloaded 6,160 times
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  • Site-wide: 2,573
  • In genetics: 83
• Year to date:
  • Site-wide: 244
• Since beginning of last month:
  • Site-wide: 641

Biological and clinical insights from genetics of insomnia symptoms

• Downloaded 3,112 times
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  • Site-wide: 6,754
  • In genomics: 690
• Year to date:
  • Site-wide: 6,335
• Since beginning of last month:
  • Site-wide: 3,812

Genome-wide association analyses of chronotype in 697,828 individuals provides new insights into circadian rhythms in humans and links to disease

• Downloaded 2,707 times
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  • Site-wide: 8,237
  • In genetics: 309
• Year to date:
  • Site-wide: 63,351
• Since beginning of last month:
  • Site-wide: 69,387

Investigating causal relationships between sleep traits and risk of breast cancer: a Mendelian randomization study

• Downloaded 2,131 times
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  • Site-wide: 11,840
  • In epidemiology: 900
• Year to date:
  • Site-wide: 107,250
• Since beginning of last month:
  • Site-wide: 107,493

Operating Characteristics of the Rank-Based Inverse Normal Transformation for Quantitative Trait Analysis in Genome-Wide Association Studies

• Downloaded 2,021 times
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  • Site-wide: 12,775
  • In genetics: 494
• Year to date:
  • Site-wide: 26,194
• Since beginning of last month:
  • Site-wide: 37,002

Genome-wide association analysis identifies novel loci for chronotype in 100,420 individuals from the UKBiobank

• Downloaded 1,933 times
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  • Site-wide: 13,686
  • In genetics: 520
• Year to date:
  • Site-wide: 153,955
• Since beginning of last month:
  • Site-wide: 150,780

GWAS in 446,118 European adults identifies 78 genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates

• Downloaded 1,658 times
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  • Site-wide: 17,328
  • In genetics: 692
• Year to date:
  • Site-wide: 107,468
• Since beginning of last month:
  • Site-wide: 53,539

Genetic studies of accelerometer-based sleep measures in 85,670 individuals yield new insights into human sleep behaviour

• Downloaded 1,485 times
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  • Site-wide: 20,628
  • In genetics: 825
• Year to date:
  • Site-wide: 105,780
• Since beginning of last month:
  • Site-wide: 69,386

Genome-wide association analyses of sleep disturbance traits identify new loci and highlight shared genetics with neuropsychiatric and metabolic traits

• Downloaded 1,479 times
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  • Site-wide: 20,772
  • In genetics: 827
• Year to date:
  • Site-wide: 167,264
• Since beginning of last month:
  • Site-wide: 129,363

The Trans-Ancestral Genomic Architecture of Glycaemic Traits

• Downloaded 1,280 times
• Download rankings, all-time:
  • Site-wide: 26,133
  • In genetics: 1,018
• Year to date:
  • Site-wide: 109,558
• Since beginning of last month:
  • Site-wide: 142,335

Large-Scale Genome-Wide Meta Analysis of Polycystic Ovary Syndrome Suggests Shared Genetic Architecture for Different Diagnosis Criteria.

• Downloaded 1,197 times
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  • Site-wide: 29,007
  • In genetics: 1,130
• Year to date:
  • Site-wide: 158,712
• Since beginning of last month:
  • Site-wide: 149,635

Trans-ancestry genome-wide association study identifies novel genetic mechanisms in rheumatoid arthritis

• Downloaded 1,154 times
• Download rankings, all-time:
  • Site-wide: 30,699
  • In genetic and genomic medicine: 240
• Year to date:
  • Site-wide: 5,156
• Since beginning of last month:
  • Site-wide: 4,057

Variant Curation Expert Panel Recommendations for RYR1 Pathogenicity Assertions in Malignant Hyperthermia Susceptibility

• Downloaded 704 times
• Download rankings, all-time:
  • Site-wide: 64,750
  • In genetics: 2,488
• Year to date:
  • Site-wide: 115,952
• Since beginning of last month:
  • Site-wide: 135,167

Genetic determinants of daytime napping and effects on cardiometabolic health

• Downloaded 688 times
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  • Site-wide: 66,947
  • In genetic and genomic medicine: 390
• Year to date:
  • Site-wide: 143,180
• Since beginning of last month:
  • Site-wide: 162,207

Night Shift Work Increases the Risk of Asthma

• Downloaded 663 times
• Download rankings, all-time:
  • Site-wide: 70,379
  • In epidemiology: 3,192
• Year to date:
  • Site-wide: 129,764
• Since beginning of last month:
  • Site-wide: 118,782

Genome-wide association analysis of excessive daytime sleepiness identifies 42 loci that suggest phenotypic subgroups

• Downloaded 658 times
• Download rankings, all-time:
  • Site-wide: 71,105
  • In genomics: 4,681
• Year to date:
  • Site-wide: 185,712
• Since beginning of last month:
  • Site-wide: 122,513

Is disrupted sleep a risk factor for Alzheimers disease? Evidence from a two-sample Mendelian randomization analysis

• Downloaded 644 times
• Download rankings, all-time:
  • Site-wide: 73,284
  • In epidemiology: 3,265
• Year to date:
  • Site-wide: 204,691
• Since beginning of last month:
  • Site-wide: 170,420

Shared heritability and functional enrichment across six solid cancers

• Downloaded 638 times
• Download rankings, all-time:
  • Site-wide: 74,232
  • In genomics: 4,896
• Year to date:
  • Site-wide: 153,602
• Since beginning of last month:
  • Site-wide: 44,319

The public health impact of poor sleep on severe COVID-19, influenza and upper respiratory infections

• Downloaded 631 times
• Download rankings, all-time:
  • Site-wide: 75,307
  • In public and global health: 1,378
• Year to date:
  • Site-wide: 7,257
• Since beginning of last month:
  • Site-wide: 11,330

Multi-trait genome-wide association meta-analysis of dietary intake identifies new loci and genetic and functional links with metabolic traits

• Downloaded 612 times
• Download rankings, all-time:
  • Site-wide: 78,255
  • In genetics: 2,940
• Year to date:
  • Site-wide: 155,923
• Since beginning of last month:
  • Site-wide: 168,726

Pathway-specific Polygenic Risk Scores (PRS) identify OSA-related pathways differentially moderating genetic susceptibility to CAD

• Downloaded 588 times
• Download rankings, all-time:
  • Site-wide: 82,163
  • In cardiovascular medicine: 184
• Year to date:
  • Site-wide: 29,320
• Since beginning of last month:
  • Site-wide: 35,754

Whole-Genome Association Analyses of Sleep-disordered Breathing Phenotypes in the NHLBI TOPMed Program

• Downloaded 582 times
• Download rankings, all-time:
  • Site-wide: 83,380
  • In genetics: 3,170
• Year to date:
  • Site-wide: 179,599
• Since beginning of last month:
  • Site-wide: 110,261

Nightmares share strong genetic risk with sleep and psychiatric disorders

• Downloaded 556 times
• Download rankings, all-time:
  • Site-wide: 88,173
  • In genetics: 3,411
• Year to date:
  • Site-wide: 89,989
• Since beginning of last month:
  • Site-wide: 119,101

Assessing the causal role of sleep traits on glycated haemoglobin: a Mendelian randomization study

• Downloaded 413 times
• Download rankings, all-time:
  • Site-wide: 121,145
  • In epidemiology: 5,048
• Year to date:
  • Site-wide: 99,205
• Since beginning of last month:
  • Site-wide: 134,430

Low daytime light and bright night-time light are associated with psychiatric disorders: an objective light study in >85,000 UK Biobank participants

• Downloaded 412 times
• Download rankings, all-time:
  • Site-wide: 121,479
  • In psychiatry and clinical psychology: None
• Year to date:
  • Site-wide: 14,736
• Since beginning of last month:
  • Site-wide: 514

Epigenome-wide association analysis of daytime sleepiness in the Multi-Ethnic Study of Atherosclerosis reveals African-American specific associations

• Downloaded 410 times
• Download rankings, all-time:
  • Site-wide: 122,061
  • In genomics: 6,750
• Year to date:
  • Site-wide: 179,103
• Since beginning of last month:
  • Site-wide: 122,372

The impact of Mendelian sleep and circadian genetic variants in a population setting

• Downloaded 315 times
• Download rankings, all-time:
  • Site-wide: 149,865
  • In genetic and genomic medicine: 1,038
• Year to date:
  • Site-wide: 22,717
• Since beginning of last month:
  • Site-wide: 84,933

Risk of preeclampsia in patients with genetic predisposition to common medical conditions: a case-control study

• Downloaded 314 times
• Download rankings, all-time:
  • Site-wide: 149,949
  • In genetics: 5,501
• Year to date:
  • Site-wide: 185,426
• Since beginning of last month:
  • Site-wide: 143,156

A Novel Home-Based Study of Circadian Rhythms: Design, Rationale, and Methods for the Circadia Study.

• Downloaded 219 times
• Download rankings, all-time:
  • Site-wide: 177,043
  • In genetic and genomic medicine: 1,304
• Year to date:
  • Site-wide: 39,192
• Since beginning of last month:
  • Site-wide: 55,405

Multi-ancestry genome-wide analysis identifies common genetic variants for self-reported sleep duration and shared genetic effects

• Downloaded 209 times
• Download rankings, all-time:
  • Site-wide: 179,434
  • In genomics: 8,608
• Year to date:
  • Site-wide: 41,791
• Since beginning of last month:
  • Site-wide: 85,320

Genome-wide gene by environment study of time spent in daylight and chronotype identifies emerging genetic architecture underlying light sensitivity

• Downloaded 137 times
• Download rankings, all-time:
  • Site-wide: 194,631
  • In genetic and genomic medicine: 1,465
• Year to date:
  • Site-wide: 69,894
• Since beginning of last month:
  • Site-wide: 96,079

Updated Variant Curation Expert Panel Criteria and Pathogenicity Classifications for 251 Variants for RYR1-related Malignant Hyperthermia Susceptibility

• Downloaded 119 times
• Download rankings, all-time:
  • Site-wide: 197,610
  • In genetics: 6,916
• Year to date:
  • Site-wide: 80,088
• Since beginning of last month:
  • Site-wide: 17,689

A transformer model for predicting cognitive impairment from sleep

• Downloaded 116 times
• Download rankings, all-time:
  • Site-wide: 198,130
  • In neuroscience: None
• Year to date:
  • Site-wide: 81,868
• Since beginning of last month:
  • Site-wide: 105,028

The causal role of accelerometer-derived sleep traits on glycated haemoglobin: a Mendelian randomization study

• Downloaded 62 times
• Download rankings, all-time:
  • Site-wide: 206,379
  • In epidemiology: None
• Year to date:
  • Site-wide: 140,692
• Since beginning of last month:
  • Site-wide: 10,506