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Author: Chia-Yen Chen

Rankings

  • All-time downloads: 38,753 (rank: 4,707 )
  • Categories:
    • biochemistry: 701 (rank: 8,989 (tie) )
    • genetic and genomic medicine: 4,294 (rank: 374 )
    • genetics: 29,058 (rank: 226 )
    • genomics: 4,236 (rank: 6,183 )
    • psychiatry and clinical psychology: 464 (rank: 2,801 (tie) )

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Preprints

Validation of a Trans-Ancestry Polygenic Risk Score for Type 2 Diabetes in Diverse Populations

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Phenome-wide Heritability Analysis of the UK Biobank

genetics more details view paper
  • Downloaded 4,034 times
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    • Site-wide: 3,233
    • In genetics: 108
  • Year to date:
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  • Since beginning of last month:
    • Site-wide: 107,209

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

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  • Downloaded 3,604 times
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    • Site-wide: 3,791
    • In genetics: 133
  • Year to date:
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  • Since beginning of last month:
    • Site-wide: 107,866

Comparative genetic architectures of schizophrenia in East Asian and European populations

genetics more details view paper
  • Downloaded 2,355 times
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    • Site-wide: 6,973
    • In genetics: 305
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    • Site-wide: 89,729

The Shared Genetic Basis of Educational Attainment and Cerebral Cortical Morphology

genetics more details view paper
  • Downloaded 2,316 times
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    • Site-wide: 7,140
    • In genetics: 314
  • Year to date:
    • Site-wide: 34,061
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Largest genome-wide association study for PTSD identifies genetic risk loci in European and African ancestries and implicates novel biological pathways

genetics more details view paper
  • Downloaded 1,849 times
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    • Site-wide: 9,939
    • In genetics: 436
  • Year to date:
    • Site-wide: 22,603
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Widespread pleiotropy confounds causal relationships between complex traits and diseases inferred from Mendelian randomization

genomics more details view paper
  • Downloaded 1,592 times
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    • Site-wide: 12,371
    • In genomics: 1,273
  • Year to date:
    • Site-wide: 70,502
  • Since beginning of last month:
    • Site-wide: 94,483

Penetrance and pleiotropy of polygenic risk scores for schizophrenia in 106,160 patients across four healthcare systems

genetics more details view paper
  • Downloaded 1,504 times
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    • Site-wide: 13,431
    • In genetics: 607
  • Year to date:
    • Site-wide: 125,016
  • Since beginning of last month:
    • Site-wide: 111,466

Polygenic Prediction via Bayesian Regression and Continuous Shrinkage Priors

genetics more details view paper
  • Downloaded 1,475 times
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    • Site-wide: 13,839
    • In genetics: 636
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    • Site-wide: 76,637
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Improving Polygenic Prediction in Ancestrally Diverse Populations

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  • Downloaded 1,454 times
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    • Site-wide: 14,164
    • In genetic and genomic medicine: 62
  • Year to date:
    • Site-wide: 1,956
  • Since beginning of last month:
    • Site-wide: 2,164

Sex-Dependent Shared and Non-Shared Genetic Architecture Across Mood and Psychotic Disorders

genetics more details view paper
  • Downloaded 1,339 times
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    • Site-wide: 16,063
    • In genetics: 740
  • Year to date:
    • Site-wide: 5,588
  • Since beginning of last month:
    • Site-wide: 33,047

Analysis across Taiwan Biobank, Biobank Japan and UK Biobank identifies hundreds of novel loci for 36 quantitative traits

genetic and genomic medicine more details view paper
  • Downloaded 1,333 times
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    • Site-wide: 16,180
    • In genetic and genomic medicine: 70
  • Year to date:
    • Site-wide: 2,220
  • Since beginning of last month:
    • Site-wide: 33,618

Brain expression quantitative trait locus and network analysis reveals downstream effects and putative drivers for brain-related diseases

genomics more details view paper
  • Downloaded 1,326 times
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    • Site-wide: 16,302
    • In genomics: 1,614
  • Year to date:
    • Site-wide: 2,239
  • Since beginning of last month:
    • Site-wide: 65,829

Lifelong genetically lowered sclerostin and risk of cardiovascular disease.

genetics more details view paper
  • Downloaded 1,300 times
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    • Site-wide: 16,818
    • In genetics: 780
  • Year to date:
    • Site-wide: 57,253
  • Since beginning of last month:
    • Site-wide: 16,099

The genetic architecture of sporadic and recurrent miscarriage

genetics more details view paper
  • Downloaded 1,197 times
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    • Site-wide: 18,978
    • In genetics: 881
  • Year to date:
    • Site-wide: 60,927
  • Since beginning of last month:
    • Site-wide: 38,219

Testing Causal Bidirectional Influences between Physical Activity and Depression using Mendelian Randomization

genetics more details view paper
  • Downloaded 1,141 times
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    • Site-wide: 20,391
    • In genetics: 939
  • Year to date:
    • Site-wide: 99,140
  • Since beginning of last month:
    • Site-wide: 109,197

The burden of rare protein-truncating genetic variants on human lifespan

genetics more details view paper
  • Downloaded 1,050 times
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    • Site-wide: 23,016
    • In genetics: 1,056
  • Year to date:
    • Site-wide: 43,996
  • Since beginning of last month:
    • Site-wide: 87,362

The causal role of circulating vitamin D concentrations in human complex traits and diseases: a large-scale Mendelian randomization study

genetics more details view paper
  • Downloaded 964 times
  • Download rankings, all-time:
    • Site-wide: 26,112
    • In genetics: 1,192
  • Year to date:
    • Site-wide: 74,656
  • Since beginning of last month:
    • Site-wide: None

GWAS identifies novel risk locus for erectile dysfunction and implicates hypothalamic neurobiology and diabetes in etiology

genomics more details view paper
  • Downloaded 925 times
  • Download rankings, all-time:
    • Site-wide: 27,674
    • In genomics: 2,505
  • Year to date:
    • Site-wide: 140,941
  • Since beginning of last month:
    • Site-wide: 94,660

Exome sequencing in bipolar disorder reveals shared risk gene AKAP11 with schizophrenia

genetic and genomic medicine more details view paper
  • Downloaded 751 times
  • Download rankings, all-time:
    • Site-wide: 37,105
    • In genetic and genomic medicine: 145
  • Year to date:
    • Site-wide: 4,983
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    • Site-wide: 2,713

A two-stage approach to identifying and validating modifiable factors for the prevention of depression

genetics more details view paper
  • Downloaded 734 times
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    • Site-wide: 38,248
    • In genetics: 1,719
  • Year to date:
    • Site-wide: 109,889
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The schizophrenia risk locus in SLC39A8 alters brain metal transport and plasma glycosylation

biochemistry more details view paper
  • Downloaded 701 times
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    • Site-wide: 40,684
    • In biochemistry: 1,020
  • Year to date:
    • Site-wide: 100,780
  • Since beginning of last month:
    • Site-wide: 30,177

Prospective Study of Polygenic Risk, Protective Factors, and Incident Depression Following Combat Deployment in US Army Soldiers

genetics more details view paper
  • Downloaded 642 times
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    • Site-wide: 45,679
    • In genetics: 2,032
  • Year to date:
    • Site-wide: 60,310
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    • Site-wide: None

Analysis of Genetically Regulated Gene Expression identifies a trauma type specific PTSD gene, SNRNP35

genetics more details view paper
  • Downloaded 637 times
  • Download rankings, all-time:
    • Site-wide: 46,110
    • In genetics: 2,055
  • Year to date:
    • Site-wide: 129,441
  • Since beginning of last month:
    • Site-wide: 63,342

GWAS meta-analysis highlights the hypothalamic-pituitary-gonadal axis (HPG axis) in the genetic regulation of menstrual cycle length

genetics more details view paper
  • Downloaded 623 times
  • Download rankings, all-time:
    • Site-wide: 47,480
    • In genetics: 2,117
  • Year to date:
    • Site-wide: 109,035
  • Since beginning of last month:
    • Site-wide: 52,783

Explicit modeling of ancestry improves polygenic risk scores and BLUP prediction

genetics more details view paper
  • Downloaded 571 times
  • Download rankings, all-time:
    • Site-wide: 52,916
    • In genetics: 2,338
  • Year to date:
    • Site-wide: 144,163
  • Since beginning of last month:
    • Site-wide: 106,996

Genomewide Analyses of Psychological Resilience in US Army Soldiers

genetics more details view paper
  • Downloaded 552 times
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    • Site-wide: 55,203
    • In genetics: 2,430
  • Year to date:
    • Site-wide: 141,318
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    • Site-wide: 106,637

Contribution of rare copy number variants to bipolar disorder risk is limited to schizoaffective cases

genetics more details view paper
  • Downloaded 545 times
  • Download rankings, all-time:
    • Site-wide: 56,040
    • In genetics: 2,471
  • Year to date:
    • Site-wide: 123,782
  • Since beginning of last month:
    • Site-wide: 30,303

Elucidating the Joint Genetic Architecture of Mood Disorder and Schizophrenia

genetic and genomic medicine more details view paper
  • Downloaded 402 times
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    • Site-wide: 77,770
    • In genetic and genomic medicine: 335
  • Year to date:
    • Site-wide: 38,164
  • Since beginning of last month:
    • Site-wide: 42,846

Genomic Influences on Self-Reported Childhood Maltreatment

genomics more details view paper
  • Downloaded 393 times
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    • Site-wide: 79,406
    • In genomics: 5,249
  • Year to date:
    • Site-wide: 140,987
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Causal influence of dietary habits on the risk of major depressive disorder: a diet-wide Mendelian randomization analysis

psychiatry and clinical psychology more details view paper
  • Downloaded 369 times
  • Download rankings, all-time:
    • Site-wide: 83,984
    • In psychiatry and clinical psychology: 312
  • Year to date:
    • Site-wide: 43,861
  • Since beginning of last month:
    • Site-wide: 31,993

Genetic validation of bipolar disorder identified by automated phenotyping using electronic health records

genetics more details view paper
  • Downloaded 360 times
  • Download rankings, all-time:
    • Site-wide: 85,910
    • In genetics: 3,737
  • Year to date:
    • Site-wide: 153,042
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    • Site-wide: None

Whole exome sequencing in the UK Biobank reveals risk gene SLC2A1 and biological insights for major depressive disorder

genetic and genomic medicine more details view paper
  • Downloaded 354 times
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    • Site-wide: 87,120
    • In genetic and genomic medicine: 383
  • Year to date:
    • Site-wide: 14,903
  • Since beginning of last month:
    • Site-wide: 64,384

Pairwise genetic interactions modulate lipid plasma levels and cellular uptake

genetics more details view paper
  • Downloaded 266 times
  • Download rankings, all-time:
    • Site-wide: 107,036
    • In genetics: 4,537
  • Year to date:
    • Site-wide: 88,417
  • Since beginning of last month:
    • Site-wide: 122,865

Dissecting Biological Pathways of Psychopathology using Cognitive Genomics

psychiatry and clinical psychology more details view paper
  • Downloaded 95 times
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    • Site-wide: 146,216
    • In psychiatry and clinical psychology: 867
  • Year to date:
    • Site-wide: 70,241
  • Since beginning of last month:
    • Site-wide: 64,279

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