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Author: Eric Vallabh Minikel

Rankings

  • All-time downloads: 69,706 (rank: 2,868 )
  • Categories:
    • biochemistry: 1,346 (rank: 4,936 (tie) )
    • genetics: 2,110 (rank: 9,927 (tie) )
    • genomics: 55,784 (rank: 188 )
    • neurology: 8,017 (rank: 136 )
    • neuroscience: 2,449 (rank: 11,832 (tie) )

Downloads per author, site-wide

Preprints

The mutational constraint spectrum quantified from variation in 141,456 humans

genomics more details view paper
  • Downloaded 25,376 times
  • Download rankings, all-time:
    • Site-wide: 375
    • In genomics: 11
  • Year to date:
    • Site-wide: 5,393
  • Since beginning of last month:
    • Site-wide: 5,084

Analysis of protein-coding genetic variation in 60,706 humans

genomics more details view paper
  • Downloaded 22,239 times
  • Download rankings, all-time:
    • Site-wide: 428
    • In genomics: 13
  • Year to date:
    • Site-wide: 53,075
  • Since beginning of last month:
    • Site-wide: 27,657

Autoantibodies against the prion protein in individuals with PRNP mutations

neurology more details view paper
  • Downloaded 7,301 times
  • Download rankings, all-time:
    • Site-wide: 1,685
    • In neurology: 5
  • Year to date:
    • Site-wide: 19,218
  • Since beginning of last month:
    • Site-wide: 2,857

Evaluating potential drug targets through human loss-of-function genetic variation

genomics more details view paper
  • Downloaded 5,304 times
  • Download rankings, all-time:
    • Site-wide: 2,591
    • In genomics: 223
  • Year to date:
    • Site-wide: 28,821
  • Since beginning of last month:
    • Site-wide: 60,171

Reassessment of Mendelian gene pathogenicity using 7,855 cardiomyopathy cases and 60,706 reference samples

genetics more details view paper
  • Downloaded 2,110 times
  • Download rankings, all-time:
    • Site-wide: 9,553
    • In genetics: 385
  • Year to date:
    • Site-wide: 74,486
  • Since beginning of last month:
    • Site-wide: 99,112

Human loss-of-function variants suggest that partial LRRK2 inhibition is a safe therapeutic strategy for Parkinson’s disease

genomics more details view paper
  • Downloaded 2,100 times
  • Download rankings, all-time:
    • Site-wide: 9,627
    • In genomics: 942
  • Year to date:
    • Site-wide: None
  • Since beginning of last month:
    • Site-wide: 39,972

Age of onset in genetic prion disease and the design of preventive clinical trials

neuroscience more details view paper
  • Downloaded 1,008 times
  • Download rankings, all-time:
    • Site-wide: 29,230
    • In neuroscience: 3,652
  • Year to date:
    • Site-wide: 131,380
  • Since beginning of last month:
    • Site-wide: 154,315

Prion protein lowering is a disease-modifying therapy across prion strains, disease stages, and endpoints

neuroscience more details view paper
  • Downloaded 772 times
  • Download rankings, all-time:
    • Site-wide: 43,101
    • In neuroscience: 5,837
  • Year to date:
    • Site-wide: None
  • Since beginning of last month:
    • Site-wide: 129,250

Response to Shah et al: Using high-resolution variant frequencies empowers clinical genome interpretation and enables investigation of genetic architecture

genomics more details view paper
  • Downloaded 765 times
  • Download rankings, all-time:
    • Site-wide: 43,719
    • In genomics: 3,417
  • Year to date:
    • Site-wide: None
  • Since beginning of last month:
    • Site-wide: 149,997

Multimodal small-molecule screening for human prion protein binders

biochemistry more details view paper
  • Downloaded 674 times
  • Download rankings, all-time:
    • Site-wide: 52,173
    • In biochemistry: 1,352
  • Year to date:
    • Site-wide: 88,988
  • Since beginning of last month:
    • Site-wide: 131,594

Domain-specific quantification of prion protein in cerebrospinal fluid by targeted mass spectrometry

neuroscience more details view paper
  • Downloaded 669 times
  • Download rankings, all-time:
    • Site-wide: 52,641
    • In neuroscience: 7,374
  • Year to date:
    • Site-wide: None
  • Since beginning of last month:
    • Site-wide: 69,160

Cerebrospinal fluid and plasma biomarkers in individuals at risk for genetic prion disease

neurology more details view paper
  • Downloaded 548 times
  • Download rankings, all-time:
    • Site-wide: 67,955
    • In neurology: 203
  • Year to date:
    • Site-wide: 67,332
  • Since beginning of last month:
    • Site-wide: 49,869

Characterization of the prion protein binding properties of antisense oligonucleotides

biochemistry more details view paper
  • Downloaded 347 times
  • Download rankings, all-time:
    • Site-wide: 108,069
    • In biochemistry: 3,179
  • Year to date:
    • Site-wide: 125,515
  • Since beginning of last month:
    • Site-wide: 128,472

Novel quaternary structures of the human prion protein globular domain

biochemistry more details view paper
  • Downloaded 325 times
  • Download rankings, all-time:
    • Site-wide: 113,913
    • In biochemistry: 3,350
  • Year to date:
    • Site-wide: None
  • Since beginning of last month:
    • Site-wide: 62,773

Regional variability, genotypic effects, and pharmacodynamic impact on prion protein concentration in the central nervous system

neurology more details view paper
  • Downloaded 168 times
  • Download rankings, all-time:
    • Site-wide: 154,253
    • In neurology: 898
  • Year to date:
    • Site-wide: 21,051
  • Since beginning of last month:
    • Site-wide: 12,177

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