Author: Lu Wang

Downloads per author, site-wide

Preprints

Tocilizumab for treatment of mechanically ventilated patients with COVID-19

• Downloaded 6,226 times
• Download rankings, all-time:
  • Site-wide: 2,356
  • In infectious diseases: 625
• Year to date:
  • Site-wide: 27,741
• Since beginning of last month:
  • Site-wide: 23,497

Genetic tool development in marine protists: Emerging model organisms for experimental cell biology

• Downloaded 2,421 times
• Download rankings, all-time:
  • Site-wide: 8,905
  • In ecology: 83
• Year to date:
  • Site-wide: 52,995
• Since beginning of last month:
  • Site-wide: 50,679

A general strategy to develop cell permeable and fluorogenic probes for multi-colour nanoscopy

• Downloaded 2,272 times
• Download rankings, all-time:
  • Site-wide: 9,774
  • In biochemistry: 185
• Year to date:
  • Site-wide: 26,800
• Since beginning of last month:
  • Site-wide: 33,270

Post-transcriptionally impaired de novo mutations contribute to the genetic etiology of four neuropsychiatric disorders

• Downloaded 1,645 times
• Download rankings, all-time:
  • Site-wide: 15,803
  • In genomics: 1,473
• Year to date:
  • Site-wide: 57,941
• Since beginning of last month:
  • Site-wide: 65,201

LonP1 Orchestrates UPRmt and UPRER and Mitochondrial Dynamics to Regulate Heart Function

• Downloaded 1,363 times
• Download rankings, all-time:
  • Site-wide: 21,142
  • In cell biology: 658
• Year to date:
  • Site-wide: 42,095
• Since beginning of last month:
  • Site-wide: 50,672

Genomic analysis of dingoes identifies genomic regions under reversible selection during domestication and feralization

• Downloaded 1,315 times
• Download rankings, all-time:
  • Site-wide: 22,364
  • In genomics: 1,942
• Year to date:
  • Site-wide: 91,866
• Since beginning of last month:
  • Site-wide: 50,298

USP7 cooperates with NOTCH1 to drive the oncogenic transcriptional program in T cell leukemia

• Downloaded 1,219 times
• Download rankings, all-time:
  • Site-wide: 25,206
  • In cancer biology: 558
• Year to date:
  • Site-wide: 170,906
• Since beginning of last month:
  • Site-wide: 171,147

Paired SARS-CoV-2 Spike Protein Mutations Observed During Ongoing SARS-CoV-2 Viral Transfer from Humans to Minks and Back to Humans

• Downloaded 1,120 times
• Download rankings, all-time:
  • Site-wide: 28,667
  • In genetics: 1,238
• Year to date:
  • Site-wide: 50,521
• Since beginning of last month:
  • Site-wide: 21,978

Fructose Metabolism Contributes to the Warburg effect

• Downloaded 1,051 times
• Download rankings, all-time:
  • Site-wide: 31,503
  • In cancer biology: 922
• Year to date:
  • Site-wide: 21,675
• Since beginning of last month:
  • Site-wide: 13,232

Subtype-specific epigenomic landscape and 3D genome structure in bladder cancer

• Downloaded 1,038 times
• Download rankings, all-time:
  • Site-wide: 32,102
  • In genomics: 2,596
• Year to date:
  • Site-wide: 109,855
• Since beginning of last month:
  • Site-wide: 129,192

A Human 3D neural assembloid model for SARS-CoV-2 infection

• Downloaded 900 times
• Download rankings, all-time:
  • Site-wide: 39,728
  • In microbiology: 2,462
• Year to date:
  • Site-wide: 36,056
• Since beginning of last month:
  • Site-wide: 28,968

Developmental retrotransposon activation primes host immunity for future viral-clearance

• Downloaded 878 times
• Download rankings, all-time:
  • Site-wide: 41,152
  • In developmental biology: 911
• Year to date:
  • Site-wide: 43,945
• Since beginning of last month:
  • Site-wide: 83,423

Anti-IL-6 versus Anti-IL-6R Blocking Antibodies to Treat Acute Ebola Infection in BALB/c Mice: Potential Implications for Treating Cytokine Release Syndrome

• Downloaded 865 times
• Download rankings, all-time:
  • Site-wide: 42,060
  • In immunology: 1,376
• Year to date:
  • Site-wide: 69,856
• Since beginning of last month:
  • Site-wide: 71,064

Population sequencing enhances understanding of tea plant evolution

• Downloaded 849 times
• Download rankings, all-time:
  • Site-wide: 43,318
  • In genomics: 3,267
• Year to date:
  • Site-wide: 113,996
• Since beginning of last month:
  • Site-wide: 94,427

Late-life restoration of mitochondrial function reverses cardiac dysfunction in old mice

• Downloaded 842 times
• Download rankings, all-time:
  • Site-wide: 43,841
  • In physiology: 194
• Year to date:
  • Site-wide: 86,907
• Since beginning of last month:
  • Site-wide: 95,207

A synthetic peptide CTL vaccine targeting nucleocapsid confers protection from SARS-CoV-2 challenge in rhesus macaques

• Downloaded 776 times
• Download rankings, all-time:
  • Site-wide: 49,369
  • In immunology: 1,554
• Year to date:
  • Site-wide: 80,233
• Since beginning of last month:
  • Site-wide: 60,604

Systematic Tuning of Rhodamine Spirocyclization for Super-Resolution Microscopy

• Downloaded 759 times
• Download rankings, all-time:
  • Site-wide: 51,004
  • In cell biology: 2,173
• Year to date:
  • Site-wide: 57,156
• Since beginning of last month:
  • Site-wide: 80,743

PDH Mediated Mitochondrial Respiration Controls the Speed of Muscle Stem Cell Activation in Muscle Repair and Aging

• Downloaded 727 times
• Download rankings, all-time:
  • Site-wide: 54,265
  • In cell biology: 2,258
• Year to date:
  • Site-wide: 78,975
• Since beginning of last month:
  • Site-wide: 88,079

YES1 amplification: a mechanism of acquired resistance to EGFR inhibitors identified by transposon mutagenesis and clinical genomics

• Downloaded 698 times
• Download rankings, all-time:
  • Site-wide: 57,337
  • In cancer biology: 1,523
• Year to date:
  • Site-wide: 143,328
• Since beginning of last month:
  • Site-wide: 143,805

Genomic approaches reveal an endemic sub-population of gray wolves in Southern China

• Downloaded 689 times
• Download rankings, all-time:
  • Site-wide: 58,401
  • In evolutionary biology: 2,488
• Year to date:
  • Site-wide: 185,227
• Since beginning of last month:
  • Site-wide: 172,926

Identification of four linear B-cell epitopes on the SARS-CoV-2 spike protein able to elicit neutralizing antibodies

• Downloaded 683 times
• Download rankings, all-time:
  • Site-wide: 59,217
  • In microbiology: 3,531
• Year to date:
  • Site-wide: 82,243
• Since beginning of last month:
  • Site-wide: 67,904

Evaluating transmission heterogeneity and super-spreading event of COVID-19 in a metropolis of China

• Downloaded 674 times
• Download rankings, all-time:
  • Site-wide: 60,339
  • In infectious diseases: 3,790
• Year to date:
  • Site-wide: 109,421
• Since beginning of last month:
  • Site-wide: 120,840

Structural insights into the activation of human calcium-sensing receptor

• Downloaded 660 times
• Download rankings, all-time:
  • Site-wide: 61,983
  • In biophysics: 2,060
• Year to date:
  • Site-wide: 73,856
• Since beginning of last month:
  • Site-wide: 97,039

Mechanisms of self-assembly and fibrillization of the prion-like domains

• Downloaded 613 times
• Download rankings, all-time:
  • Site-wide: 68,305
  • In biophysics: 2,122
• Year to date:
  • Site-wide: 189,006
• Since beginning of last month:
  • Site-wide: 183,828

Assortative mating on ancestry-variant traits in admixed Latin American populations

• Downloaded 598 times
• Download rankings, all-time:
  • Site-wide: 70,526
  • In genomics: 4,584
• Year to date:
  • Site-wide: 176,853
• Since beginning of last month:
  • Site-wide: 147,266

Evolution of Natural Lifespan Variation and Molecular Strategies of Extended Lifespan

• Downloaded 595 times
• Download rankings, all-time:
  • Site-wide: 70,897
  • In genetics: 2,857
• Year to date:
  • Site-wide: 90,762
• Since beginning of last month:
  • Site-wide: 66,744

A single-cell transcriptome atlas during Cashmere goat hair follicle morphogenesis

• Downloaded 558 times
• Download rankings, all-time:
  • Site-wide: 76,776
  • In developmental biology: 1,985
• Year to date:
  • Site-wide: 67,206
• Since beginning of last month:
  • Site-wide: 62,803

Insufficiency in airway interferon activation defines clinical severity to infant RSV infection

• Downloaded 473 times
• Download rankings, all-time:
  • Site-wide: 93,060
  • In genomics: 5,538
• Year to date:
  • Site-wide: 169,540
• Since beginning of last month:
  • Site-wide: 163,547

Synthesis-Free PET Imaging Of Brown Adipose Tissue And TSPO Via Combination Of Disulfiram And 64CuCl2

• Downloaded 459 times
• Download rankings, all-time:
  • Site-wide: 96,264
  • In pharmacology and toxicology: 578
• Year to date:
  • Site-wide: 175,460
• Since beginning of last month:
  • Site-wide: 171,753

Prediction of motor outcome after acute stroke using rich-club organizational analysis

• Downloaded 457 times
• Download rankings, all-time:
  • Site-wide: 96,606
  • In radiology and imaging: 183
• Year to date:
  • Site-wide: 67,220
• Since beginning of last month:
  • Site-wide: 63,039

Recovery and Community Succession of the Zostera marina Rhizobiome After Transplantation

• Downloaded 448 times
• Download rankings, all-time:
  • Site-wide: 98,731
  • In microbiology: 6,218
• Year to date:
  • Site-wide: 138,538
• Since beginning of last month:
  • Site-wide: 179,104

Towards Staining Independent Segmentation of Glomerulus from Histopathological Images of Kidney

• Downloaded 441 times
• Download rankings, all-time:
  • Site-wide: 100,328
  • In pathology: 459
• Year to date:
  • Site-wide: 157,870
• Since beginning of last month:
  • Site-wide: 178,915

Airway Gene-Expression Classifiers for Respiratory Syncytial Virus (RSV) Disease Severity in Infants

• Downloaded 416 times
• Download rankings, all-time:
  • Site-wide: 106,156
  • In immunology: 3,084
• Year to date:
  • Site-wide: 139,850
• Since beginning of last month:
  • Site-wide: 148,924

Measuring aptamer folding energy using a molecular clamp

• Downloaded 415 times
• Download rankings, all-time:
  • Site-wide: 106,345
  • In biophysics: 3,922
• Year to date:
  • Site-wide: 109,481
• Since beginning of last month:
  • Site-wide: 63,453

POU2AF2/C11orf53 functions as a co-activator of POU2F3 by maintaining chromatin accessibility and enhancer activity

• Downloaded 411 times
• Download rankings, all-time:
  • Site-wide: 107,534
  • In cancer biology: None
• Year to date:
  • Site-wide: 6,658
• Since beginning of last month:
  • Site-wide: 6,271

Landscape of glioblastoma niches reveals the prognostic effects of tumor-infiltrating cells

• Downloaded 332 times
• Download rankings, all-time:
  • Site-wide: 128,705
  • In cancer biology: 3,609
• Year to date:
  • Site-wide: 161,458
• Since beginning of last month:
  • Site-wide: 181,190

Multi-omic Characterization of Human Tubular Epithelial Cell Response to Serum

• Downloaded 327 times
• Download rankings, all-time:
  • Site-wide: 129,933
  • In cell biology: 5,839
• Year to date:
  • Site-wide: 108,788
• Since beginning of last month:
  • Site-wide: 168,539

Revision of the genus Dichaetophora Duda (Diptera: Drosophilidae), part I: DNA bar-coding and molecular phylogenetic reconstruction

• Downloaded 308 times
• Download rankings, all-time:
  • Site-wide: 135,819
  • In zoology: 557
• Year to date:
  • Site-wide: 90,564
• Since beginning of last month:
  • Site-wide: 64,293

Genomics-informed insights into microbial degradation of N,N-dimethylformamide

• Downloaded 281 times
• Download rankings, all-time:
  • Site-wide: 143,778
  • In microbiology: 10,924
• Year to date:
  • Site-wide: 62,672
• Since beginning of last month:
  • Site-wide: 21,914

Fusobacterium nucleatum facilitates cetuximab resistance in colorectal cancer via the PI3K/AKT and JAK/STAT3 pathways

• Downloaded 277 times
• Download rankings, all-time:
  • Site-wide: 145,010
  • In cancer biology: 4,336
• Year to date:
  • Site-wide: 93,112
• Since beginning of last month:
  • Site-wide: 59,364

Increased Risk for Cerebral Small Vessel Disease is Associated with Quantitative Susceptibility Mapping in HIV Infected and Uninfected Individuals

• Downloaded 268 times
• Download rankings, all-time:
  • Site-wide: 147,758
  • In pathology: 888
• Year to date:
  • Site-wide: 67,797
• Since beginning of last month:
  • Site-wide: 24,176

Calorie Restriction Prevents Age-Related Changes in the Intestinal Microbiota

• Downloaded 250 times
• Download rankings, all-time:
  • Site-wide: 152,879
  • In molecular biology: 4,364
• Year to date:
  • Site-wide: 137,347
• Since beginning of last month:
  • Site-wide: 88,742

Radiosynthesis and preclinical evaluation of a carbon-11 labeled PDE7 inhibitor for PET neuroimaging

• Downloaded 246 times
• Download rankings, all-time:
  • Site-wide: 154,069
  • In neuroscience: 22,659
• Year to date:
  • Site-wide: 57,286
• Since beginning of last month:
  • Site-wide: 124,848

Learning Clique Subgraphs in Structural Brain Network Classification with Application to Crystallized Cognition

• Downloaded 237 times
• Download rankings, all-time:
  • Site-wide: 156,719
  • In neuroscience: 21,738
• Year to date:
  • Site-wide: 183,018
• Since beginning of last month:
  • Site-wide: 179,912

Risk modelling of single cell populations revealed the heterogeneity of immune infiltration in hepatocellular carcinoma

• Downloaded 230 times
• Download rankings, all-time:
  • Site-wide: 158,743
  • In bioinformatics: 12,673
• Year to date:
  • Site-wide: 34,115
• Since beginning of last month:
  • Site-wide: 28,550

Deactivation of SARS-CoV-2 surrogate porcine epidemic diarrhea virus with electron beam irradiation under the cold chain transportation condition

• Downloaded 208 times
• Download rankings, all-time:
  • Site-wide: 164,650
  • In microbiology: 11,965
• Year to date:
  • Site-wide: 60,299
• Since beginning of last month:
  • Site-wide: 89,853

A systems genomics approach uncovers molecular associates of RSV severity

• Downloaded 191 times
• Download rankings, all-time:
  • Site-wide: 168,916
  • In genomics: 7,897
• Year to date:
  • Site-wide: 171,651
• Since beginning of last month:
  • Site-wide: 180,865

Comprehensive Network Analysis and Experimental Verification of Dedu Safflower's Influence on Ascites Hepatocarcinoma

• Downloaded 187 times
• Download rankings, all-time:
  • Site-wide: 169,800
  • In cancer biology: 4,900
• Year to date:
  • Site-wide: 172,251
• Since beginning of last month:
  • Site-wide: 152,899

Acarbose suppresses symptoms of mitochondrial disease in a mouse model of Leigh Syndrome

• Downloaded 179 times
• Download rankings, all-time:
  • Site-wide: 171,728
  • In biochemistry: 5,394
• Year to date:
  • Site-wide: 22,741
• Since beginning of last month:
  • Site-wide: 20,084

Hexose translocation mediated by SlSWEET5b is required for pollen maturation in Solanum lycopersicum

• Downloaded 171 times
• Download rankings, all-time:
  • Site-wide: 173,580
  • In plant biology: 4,765
• Year to date:
  • Site-wide: 64,381
• Since beginning of last month:
  • Site-wide: 49,426

AMPK mediates early activation of the unfolded protein response through a positive feedback loop in palmitate-treated muscle cells

• Downloaded 151 times
• Download rankings, all-time:
  • Site-wide: 177,867
  • In physiology: 2,171
• Year to date:
  • Site-wide: 54,046
• Since beginning of last month:
  • Site-wide: 52,785

neoDL: A novel neoantigen intrinsic feature-based deep learning model identifies IDH wild-type glioblastomas with the longest survival

• Downloaded 138 times
• Download rankings, all-time:
  • Site-wide: 180,136
  • In bioinformatics: 12,638
• Year to date:
  • Site-wide: 171,787
• Since beginning of last month:
  • Site-wide: 155,172

PIMT suppresses endothelial activation and vascular inflammation through methylation of TRAF6

• Downloaded 96 times
• Download rankings, all-time:
  • Site-wide: 186,163
  • In physiology: 2,275
• Year to date:
  • Site-wide: 48,055
• Since beginning of last month:
  • Site-wide: 79,614

Genetic Variation and Disease Severity of Respiratory Syncytial Viruses

• Downloaded 91 times
• Download rankings, all-time:
  • Site-wide: 186,731
  • In microbiology: None
• Year to date:
  • Site-wide: 50,966
• Since beginning of last month:
  • Site-wide: 121,288

Characterizing brain imaging features associated with ADAS-Cog13 sub-scores with 3D convolutional neural networks

• Downloaded 61 times
• Download rankings, all-time:
  • Site-wide: 189,233
  • In neuroscience: None
• Year to date:
  • Site-wide: 74,329
• Since beginning of last month:
  • Site-wide: 106,255