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Author: Seth A. Darst

Rankings

  • All-time downloads: 8,113 (rank: 37,949 (tie) )
  • Categories:
    • biochemistry: 819 (rank: 9,669 (tie) )
    • biophysics: 7,070 (rank: 370 )

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Preprints

Structural basis for substrate selection by the SARS-CoV-2 replicase

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Eliminating effects of particle adsorption to the air/water interface in single-particle cryo-electron microscopy: Bacterial RNA polymerase and CHAPSO

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  • Downloaded 1,955 times
  • Download rankings, all-time:
    • Site-wide: 11,912
    • In biophysics: 240
  • Year to date:
    • Site-wide: 91,910
  • Since beginning of last month:
    • Site-wide: 89,050

Structural basis for helicase-polymerase coupling in the SARS-CoV-2 replication-transcription complex

biophysics more details view paper
  • Downloaded 1,883 times
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    • Site-wide: 12,588
    • In biophysics: 269
  • Year to date:
    • Site-wide: 44,125
  • Since beginning of last month:
    • Site-wide: 28,603

Structural basis for backtracking by the SARS-CoV-2 replication-transcription complex

biochemistry more details view paper
  • Downloaded 861 times
  • Download rankings, all-time:
    • Site-wide: 40,712
    • In biochemistry: 1,025
  • Year to date:
    • Site-wide: 42,610
  • Since beginning of last month:
    • Site-wide: 54,296

Ensemble cryo-electron microscopy reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex

biophysics more details view paper
  • Downloaded 797 times
  • Download rankings, all-time:
    • Site-wide: 45,683
    • In biophysics: 1,579
  • Year to date:
    • Site-wide: 10,301
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    • Site-wide: 36,591

Fidaxomicin jams M. tuberculosis RNA polymerase motions needed for initiation via RbpA contacts

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  • Downloaded 566 times
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    • Site-wide: 72,402
    • In biophysics: 2,421
  • Year to date:
    • Site-wide: 139,687
  • Since beginning of last month:
    • Site-wide: 162,363

Structural basis for transcription complex disruption by the Mfd translocase

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  • Downloaded 557 times
  • Download rankings, all-time:
    • Site-wide: 73,792
    • In biophysics: 2,450
  • Year to date:
    • Site-wide: 175,760
  • Since beginning of last month:
    • Site-wide: 174,004

Structural basis for transcript elongation control by NusG/RfaH universal regulators

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  • Downloaded 518 times
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    • Site-wide: 80,480
    • In biophysics: 2,809
  • Year to date:
    • Site-wide: 112,255
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    • Site-wide: 113,898

E. coli TraR allosterically regulates transcription initiation by altering RNA polymerase conformation and dynamics

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  • Downloaded 452 times
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    • Site-wide: 93,717
    • In biophysics: 3,273
  • Year to date:
    • Site-wide: 131,131
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    • Site-wide: 174,404

Structural origins of Escherichia coli RNA polymerase open promoter complex stability

biophysics more details view paper
  • Downloaded 279 times
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    • Site-wide: 139,057
    • In biophysics: 5,243
  • Year to date:
    • Site-wide: 72,527
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    • Site-wide: 57,610

Structural basis for transcription activation by Crl through tethering of σS and RNA polymerase

biophysics more details view paper
  • Downloaded 245 times
  • Download rankings, all-time:
    • Site-wide: 149,074
    • In biophysics: 5,416
  • Year to date:
    • Site-wide: 184,618
  • Since beginning of last month:
    • Site-wide: 178,432

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