Author: Barney S. Graham

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Preprints

Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7

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SARS-CoV-2 mRNA Vaccine Development Enabled by Prototype Pathogen Preparedness

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  • In immunology: 12
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Cryo-EM Structure of the 2019-nCoV Spike in the Prefusion Conformation

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• Year to date:
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Structural Basis for Potent Neutralization of Betacoronaviruses by Single-domain Camelid Antibodies

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  • Site-wide: 860
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  • Site-wide: 95,307

Validation of a SARS-CoV-2 spike ELISA for use in contact investigations and serosurveillance

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  • Site-wide: 1,516
  • In immunology: 47
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Durability of mRNA-1273-induced antibodies against SARS-CoV-2 variants

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  • Site-wide: 2,603
  • In immunology: 91
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The functions of SARS-CoV-2 neutralizing and infection-enhancing antibodies in vitro and in mice and nonhuman primates

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Variant SARS-CoV-2 mRNA vaccines confer broad neutralization as primary or booster series in mice

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  • Site-wide: 3,383
  • In microbiology: 237
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  • Site-wide: 590
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  • Site-wide: 23,881

Immune Correlates of Protection by mRNA-1273 Immunization against SARS-CoV-2 Infection in Nonhuman Primates

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  • In immunology: 123
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  • Site-wide: 592
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  • Site-wide: 459

Serologic cross-reactivity of SARS-CoV-2 with endemic and seasonal Betacoronaviruses

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  • In infectious diseases: 878
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LY-CoV1404 (bebtelovimab) potently neutralizes SARS-CoV-2 variants

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Broad sarbecovirus neutralizing antibodies define a key site of vulnerability on the SARS-CoV-2 spike protein

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Trypsin treatment unlocks barrier for zoonotic coronaviruses infection

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Elicitation of broadly protective immunity to influenza by multivalent hemagglutinin nanoparticle vaccines

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  • In immunology: 395
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  • Site-wide: 10,153

Protection against SARS-CoV-2 Beta Variant in mRNA-1273 Boosted Nonhuman Primates

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  • Site-wide: 15,740
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Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes

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  • Site-wide: 16,139
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Cross-reactive coronavirus antibodies with diverse epitope specificities and extra-neutralization functions

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  • Site-wide: 17,785
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• Year to date:
  • Site-wide: 3,234
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Evaluation of mRNA-1273 against SARS-CoV-2 B.1.351 Infection in Nonhuman Primates

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  • Site-wide: 23,141
  • In immunology: 772
• Year to date:
  • Site-wide: 3,179
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  • Site-wide: 61,101

Receptor binding and proteolysis do not induce large conformational changes in the SARS-CoV spike

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  • Site-wide: 23,573
  • In biochemistry: 511
• Year to date:
  • Site-wide: 94,679
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  • Site-wide: 119,956

A broadly neutralizing antibody protects against SARS-CoV, pre-emergent bat CoVs, and SARS-CoV-2 variants in mice

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  • Site-wide: 24,600
  • In microbiology: 1,451
• Year to date:
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  • Site-wide: 124,352

A comprehensive influenza reporter virus panel for high-throughput deep profiling of neutralizing antibodies

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  • Site-wide: 43,952
  • In immunology: 1,366
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  • Site-wide: 32,779
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Human antibody immune responses are personalized by selective removal of MHC-II peptide epitopes

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  • Site-wide: 44,850
  • In immunology: 1,383
• Year to date:
  • Site-wide: 6,278
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  • Site-wide: 132,432

Design of nanoparticulate group 2 influenza hemagglutinin stem antigens that activate unmutated ancestor B cell receptors of broadly neutralizing antibody lineages

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  • Site-wide: 73,734
  • In immunology: 2,215
• Year to date:
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  • Site-wide: 24,455

Structure-based design of stabilized recombinant influenza neuraminidase tetramers

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  • Site-wide: 74,341
  • In microbiology: 4,998
• Year to date:
  • Site-wide: 11,934
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  • Site-wide: 126,208