Author: Barney S Graham

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Preprints

Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7

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  • In immunology: 10
• Year to date:
  • Site-wide: 2,008
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  • Site-wide: 2,997

SARS-CoV-2 mRNA Vaccine Development Enabled by Prototype Pathogen Preparedness

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  • Site-wide: 271
  • In immunology: 13
• Year to date:
  • Site-wide: 1,905
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  • Site-wide: 3,586

Cryo-EM Structure of the 2019-nCoV Spike in the Prefusion Conformation

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  • In microbiology: 28
• Year to date:
  • Site-wide: 113,461
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Structural Basis for Potent Neutralization of Betacoronaviruses by Single-domain Camelid Antibodies

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  • Site-wide: 1,164
  • In microbiology: 112
• Year to date:
  • Site-wide: 38,835
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  • Site-wide: 98,609

Validation of a SARS-CoV-2 spike ELISA for use in contact investigations and serosurveillance

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  • Site-wide: 1,689
  • In immunology: 69
• Year to date:
  • Site-wide: 1,434
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  • Site-wide: 3,388

Variant SARS-CoV-2 mRNA vaccines confer broad neutralization as primary or booster series in mice

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  • Site-wide: 2,356
  • In microbiology: 202
• Year to date:
  • Site-wide: 1,130
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  • Site-wide: 2,928

The functions of SARS-CoV-2 neutralizing and infection-enhancing antibodies in vitro and in mice and nonhuman primates

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  • Site-wide: 2,385
  • In immunology: 95
• Year to date:
  • Site-wide: 10,300
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  • Site-wide: 16,756

Durability of mRNA-1273-induced antibodies against SARS-CoV-2 variants

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  • Site-wide: 2,449
  • In immunology: 103
• Year to date:
  • Site-wide: 17,338
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Immune Correlates of Protection by mRNA-1273 Immunization against SARS-CoV-2 Infection in Nonhuman Primates

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  • Site-wide: 3,416
  • In immunology: 138
• Year to date:
  • Site-wide: 4,702
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  • Site-wide: 5,735

Serologic cross-reactivity of SARS-CoV-2 with endemic and seasonal Betacoronaviruses

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  • Site-wide: 5,735
  • In infectious diseases: 1,134
• Year to date:
  • Site-wide: 26,211
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  • Site-wide: 39,205

Protection from SARS-CoV-2 Delta one year after mRNA-1273 vaccination in nonhuman primates is coincident with an anamnestic antibody response in the lower airway

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  • Site-wide: 6,752
  • In immunology: 272
• Year to date:
  • Site-wide: 23,796
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  • Site-wide: 49,170

Protection against SARS-CoV-2 Beta Variant in mRNA-1273 Boosted Nonhuman Primates

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  • Site-wide: 8,087
  • In immunology: 317
• Year to date:
  • Site-wide: 39,491
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  • Site-wide: 57,071

Broad sarbecovirus neutralizing antibodies define a key site of vulnerability on the SARS-CoV-2 spike protein

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  • Site-wide: 8,369
  • In immunology: 325
• Year to date:
  • Site-wide: 76,089
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  • Site-wide: 45,372

Evaluation of mRNA-1273 against SARS-CoV-2 B.1.351 Infection in Nonhuman Primates

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  • Site-wide: 9,527
  • In immunology: 374
• Year to date:
  • Site-wide: 19,875
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  • Site-wide: 10,076

Trypsin treatment unlocks barrier for zoonotic coronaviruses infection

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  • Site-wide: 11,373
  • In microbiology: 675
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  • Site-wide: None
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  • Site-wide: 54,977

Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B.1.1.529

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  • Site-wide: 11,815
  • In immunology: 456
• Year to date:
  • Site-wide: 24,058
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  • Site-wide: 113,898

A broadly neutralizing antibody protects against SARS-CoV, pre-emergent bat CoVs, and SARS-CoV-2 variants in mice

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  • Site-wide: 12,942
  • In microbiology: 776
• Year to date:
  • Site-wide: 23,133
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  • Site-wide: 27,914

Elicitation of broadly protective immunity to influenza by multivalent hemagglutinin nanoparticle vaccines

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  • Site-wide: 14,076
  • In immunology: 535
• Year to date:
  • Site-wide: 24,357
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  • Site-wide: 101,135

Cross-reactive coronavirus antibodies with diverse epitope specificities and extra-neutralization functions

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  • Site-wide: 17,235
  • In immunology: 636
• Year to date:
  • Site-wide: 61,765
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  • Site-wide: 71,694

Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes

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  • Site-wide: 20,550
  • In immunology: 756
• Year to date:
  • Site-wide: 54,947
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  • Site-wide: 80,006

Receptor binding and proteolysis do not induce large conformational changes in the SARS-CoV spike

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  • Site-wide: 32,099
  • In biochemistry: 722
• Year to date:
  • Site-wide: 163,022
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  • Site-wide: 150,757

Human antibody immune responses are personalized by selective removal of MHC-II peptide epitopes

• Downloaded 1,082 times
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  • Site-wide: 35,331
  • In immunology: 1,298
• Year to date:
  • Site-wide: 12,669
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  • Site-wide: 72,316

Structure-based design of stabilized recombinant influenza neuraminidase tetramers

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  • Site-wide: 38,353
  • In microbiology: 2,217
• Year to date:
  • Site-wide: 80,999
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  • Site-wide: 136,465

A comprehensive influenza reporter virus panel for high-throughput deep profiling of neutralizing antibodies

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  • Site-wide: 55,206
  • In immunology: 1,885
• Year to date:
  • Site-wide: 113,889
• Since beginning of last month:
  • Site-wide: 65,462

Design of nanoparticulate group 2 influenza hemagglutinin stem antigens that activate unmutated ancestor B cell receptors of broadly neutralizing antibody lineages

• Downloaded 479 times
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  • Site-wide: 109,441
  • In immunology: 3,508
• Year to date:
  • Site-wide: 167,180
• Since beginning of last month:
  • Site-wide: 143,975

An optimized messenger RNA vaccine candidate protects non-human primates from Zika virus infection

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  • Site-wide: 186,794
  • In immunology: 6,232
• Year to date:
  • Site-wide: 10,789
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  • Site-wide: 15,537

A Multivalent Polyomavirus Vaccine Elicits Durable Neutralizing Antibody Responses in Macaques

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  • Site-wide: 200,258
  • In immunology: 6,676
• Year to date:
  • Site-wide: 9,295
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  • Site-wide: 13,862