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Author: Matthieu Schapira

  • ORCiD: http://orcid.org/0000-0002-1047-3309
  • Most recently observed institution: Structural Genomics Consortium, University of Toronto, 101 College Street, MaRS South Tower, Suite 700, Toronto, Ontario M5G 1L7, Canada

Rankings

  • All-time downloads: 11,078 (rank: 23,206 (tie) )
  • Categories:
    • biochemistry: 3,764 (rank: 1,037 )
    • bioinformatics: 1,187 (rank: 15,382 (tie) )
    • biophysics: 2,943 (rank: 1,505 (tie) )
    • cell biology: 581 (rank: 21,995 (tie) )
    • pharmacology and toxicology: 2,603 (rank: 423 )

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Preprints

A Systematic Analysis Of Atomic Protein-Ligand Interactions In The PDB

biophysics more details view paper
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The Druggable Genome as Seen from the Protein Data Bank

bioinformatics more details view paper
  • Downloaded 1,187 times
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    • Site-wide: 22,043
    • In bioinformatics: 2,487
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A Chemical Biology Toolbox for the Study of Protein Methyltransferases and Epigenetic Signaling

biochemistry more details view paper
  • Downloaded 1,183 times
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    • Site-wide: 22,154
    • In biochemistry: 477
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Identification and Structure-Activity Relationship of HDAC6 Zinc-finger Ubiquitin Binding Domain Inhibitors

biophysics more details view paper
  • Downloaded 939 times
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    • In biophysics: 920
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Structure, Mechanism and Crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase

biochemistry more details view paper
  • Downloaded 782 times
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    • Site-wide: 40,823
    • In biochemistry: 1,014
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    • Site-wide: 7,922
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Discovery of small molecule antagonists of the USP5 zinc finger ubiquitin-binding domain

pharmacology and toxicology more details view paper
  • Downloaded 756 times
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    • Site-wide: 42,876
    • In pharmacology and toxicology: 243
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Identification and Characterization of the First Fragment Hits for SETDB1 Tudor Domain

pharmacology and toxicology more details view paper
  • Downloaded 608 times
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    • In pharmacology and toxicology: 348
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Probing the SAM Binding Site of SARS-CoV-2 nsp14 in vitro Using SAM Competitive Inhibitors Guides Developing Selective bi-substrate Inhibitors

biochemistry more details view paper
  • Downloaded 602 times
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    • In biochemistry: 1,547
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Pharmacological targeting of a PWWP domain demonstrates cooperative control of NSD2 localization

cell biology more details view paper
  • Downloaded 581 times
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    • In cell biology: 2,695
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HAP40 orchestrates huntingtin structure for differential interaction with polyglutamine expanded exon 1

biochemistry more details view paper
  • Downloaded 547 times
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    • In biochemistry: 1,764
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Discovery of Small-Molecule Antagonists of the PWWP Domain of NSD2

pharmacology and toxicology more details view paper
  • Downloaded 536 times
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    • In pharmacology and toxicology: 422
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The SARS-CoV-2 replication-transcription complex is a priority target for broad-spectrum pan-coronavirus drugs

pharmacology and toxicology more details view paper
  • Downloaded 481 times
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    • Site-wide: 76,454
    • In pharmacology and toxicology: 499
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A First-in-class, Highly Selective and Cell-active AllostericInhibitor of Protein Arginine Methyltransferase 6 (PRMT6)

biochemistry more details view paper
  • Downloaded 385 times
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    • Site-wide: 95,769
    • In biochemistry: 2,764
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Structure Activity Relationship of USP5 Allosteric Inhibitors

biochemistry more details view paper
  • Downloaded 265 times
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    • Site-wide: 125,938
    • In biochemistry: 3,773
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    • Site-wide: 40,773
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Negative controls of chemical probes can be misleading

pharmacology and toxicology more details view paper
  • Downloaded 222 times
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    • Site-wide: 136,977
    • In pharmacology and toxicology: 1,107
  • Year to date:
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