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Author: Jack Bowden

Rankings

  • All-time downloads: 41,606 (rank: 6,267 )
  • Categories:
    • endocrinology: 152 (rank: 2,581 (tie) )
    • epidemiology: 23,527 (rank: 1,049 )
    • genetic and genomic medicine: 992 (rank: 6,684 )
    • genetics: 11,664 (rank: 1,698 )
    • genomics: 3,482 (rank: 9,157 (tie) )
    • neurology: 118 (rank: 12,051 (tie) )

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Preprints

Automating Mendelian randomization through machine learning to construct a putative causal map of the human phenome

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MR-Base: a platform for systematic causal inference across the phenome using billions of genetic associations

epidemiology more details view paper
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    • In epidemiology: 420
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Biological and clinical insights from genetics of insomnia symptoms

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    • In genomics: 690
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Genome-wide association analyses of chronotype in 697,828 individuals provides new insights into circadian rhythms in humans and links to disease

genetics more details view paper
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Improving the accuracy of two-sample summary data Mendelian randomization: moving beyond the NOME assumption

epidemiology more details view paper
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    • In epidemiology: 867
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The use of two-sample methods for Mendelian randomization analyses on single large datasets

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    • In genetics: 513
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An examination of multivariable Mendelian randomization in the single sample and two-sample summary data settings.

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Causal Inference for Heritable Phenotypic Risk Factors Using Heterogeneous Genetic Instruments

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GWAS in 446,118 European adults identifies 78 genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates

genetics more details view paper
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Genome-wide association analyses of sleep disturbance traits identify new loci and highlight shared genetics with neuropsychiatric and metabolic traits

genetics more details view paper
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Testing and Correcting for Weak and Pleiotropic Instruments in Two-Sample Multivariable Mendelian Randomisation

genetics more details view paper
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    • In genetics: 988
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Investigating the role of insulin in increased adiposity: Bi-directional Mendelian randomization study

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    • Site-wide: 30,958
    • In epidemiology: 1,747
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Detecting and correcting for bias in Mendelian randomization analyses using gene-by-environment interactions

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    • Site-wide: 31,363
    • In epidemiology: 1,761
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Robust inference in summary data Mendelian randomisation via the zero modal pleiotropy assumption

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    • Site-wide: 34,094
    • In epidemiology: 1,845
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The Causal Effect Of Educational Attainment On Alzheimer's Disease: A Two-Sample Mendelian Randomization Study

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    • Site-wide: 40,788
    • In epidemiology: 2,109
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Profile-likelihood Bayesian model averaging for two-sample summary data Mendelian randomization in the presence of horizontal pleiotropy

genetics more details view paper
  • Downloaded 811 times
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    • Site-wide: 52,738
    • In genetics: 2,169
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    • Site-wide: 52,172
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Mendelian randomisation with coarsened exposures

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  • Downloaded 788 times
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    • Site-wide: 54,925
    • In epidemiology: 2,700
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Education and coronary heart disease: a Mendelian randomization study

epidemiology more details view paper
  • Downloaded 708 times
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    • Site-wide: 64,206
    • In epidemiology: 2,971
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Interaction-based Mendelian randomization with measured and unmeasured gene-by-covariate interactions

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    • Site-wide: 67,950
    • In epidemiology: 3,155
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Mendelian randomisation analysis of the effect of educational attainment and cognitive ability on smoking behaviour

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    • Site-wide: 69,720
    • In epidemiology: 3,138
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Exploiting collider bias to apply two-sample summary data Mendelian randomization methods to one-sample individual level data

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  • Downloaded 660 times
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    • Site-wide: 70,810
    • In epidemiology: 3,221
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Genome-wide association analysis of excessive daytime sleepiness identifies 42 loci that suggest phenotypic subgroups

genomics more details view paper
  • Downloaded 658 times
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    • Site-wide: 71,105
    • In genomics: 4,681
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    • Site-wide: 185,712
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The median and the mode as robust meta-analysis methods in the presence of small study effects

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  • Downloaded 644 times
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    • Site-wide: 73,272
    • In epidemiology: 3,307
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    • Site-wide: 169,825
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Investigating causality in associations between education and smoking: A two-sample Mendelian randomization study

epidemiology more details view paper
  • Downloaded 597 times
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    • Site-wide: 80,734
    • In epidemiology: 3,531
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    • Site-wide: 176,533
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Navigating sample overlap, winner's curse and weak instrument bias in Mendelian randomization studies using the UK Biobank

epidemiology more details view paper
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    • Site-wide: 84,623
    • In epidemiology: 4,350
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The Triangulation WIthin A STudy (TWIST) framework for causal inference within Pharmacogenetic research

genetic and genomic medicine more details view paper
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    • Site-wide: 88,301
    • In genetic and genomic medicine: 533
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Association Between Genetically Elevated Levels Of Inflammatory Biomarkers And Risk Of Schizophrenia: A Two-Sample Mendelian Randomisation Study

epidemiology more details view paper
  • Downloaded 549 times
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    • Site-wide: 89,601
    • In epidemiology: 3,880
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    • Site-wide: 79,912

Assessing the causal role of sleep traits on glycated haemoglobin: a Mendelian randomization study

epidemiology more details view paper
  • Downloaded 413 times
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    • Site-wide: 121,145
    • In epidemiology: 5,048
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Sensitivity to missing not at random dropout in clinical trials: use and interpretation of the Trimmed Means Estimator

epidemiology more details view paper
  • Downloaded 412 times
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Genetic variation in activating clopidogrel: longer-term outcomes in a large community cohort

genetic and genomic medicine more details view paper
  • Downloaded 403 times
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    • Site-wide: 123,972
    • In genetic and genomic medicine: 813
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Evaluation of the causal effect of fibrinogen on incident coronary heart disease via Mendelian randomization

genetics more details view paper
  • Downloaded 356 times
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    • In genetics: 5,071
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Statin treatment effectiveness and the SLCO1B1*5 reduced function genotype: long-term outcomes in women and men

epidemiology more details view paper
  • Downloaded 185 times
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    • In epidemiology: 7,272
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Calcium Channel Blockers: clinical outcome associations with reported pharmacogenetics variants in 32,000 patients

epidemiology more details view paper
  • Downloaded 184 times
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    • Site-wide: 185,222
    • In epidemiology: 7,304
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Islet autoantibody level distributions in type 1 diabetes and their association with genetic and clinical characteristics

endocrinology more details view paper
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    • In endocrinology: 295
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Mid-life leukocyte telomere length and dementia risk: a prospective cohort study of 435,046 UK Biobank participants

neurology more details view paper
  • Downloaded 149 times
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    • Site-wide: 192,425
    • In neurology: 1,320
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Investigating a possible causal relationship between maternal serum urate concentrations and offspring birthweight: A Mendelian randomization study

genetic and genomic medicine more details view paper
  • Downloaded 100 times
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    • Site-wide: 200,707
    • In genetic and genomic medicine: 1,501
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Sparse Dimensionality Reduction Approaches in Mendelian Randomization with highly correlated exposures

epidemiology more details view paper
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    • In epidemiology: 7,816
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The causal role of accelerometer-derived sleep traits on glycated haemoglobin: a Mendelian randomization study

epidemiology more details view paper
  • Downloaded 62 times
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    • Site-wide: 206,379
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Dirichlet process mixture models to estimate outcomes for individuals with missing predictor data: application to predict optimal type 2 diabetes therapy in electronic health record data

epidemiology more details view paper
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