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Author: Karl Mechtler

Rankings

  • All-time downloads: 21,278 (rank: 8,755 )
  • Categories:
    • biochemistry: 8,148 (rank: 225 )
    • bioinformatics: 533 (rank: 25,184 (tie) )
    • cancer biology: 1,089 (rank: 7,711 (tie) )
    • cell biology: 6,197 (rank: 566 )
    • developmental biology: 712 (rank: 6,573 (tie) )
    • molecular biology: 1,889 (rank: 2,730 )
    • plant biology: 2,281 (rank: 1,141 )
    • synthetic biology: 429 (rank: 4,155 (tie) )

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Preprints

A cross-kingdom conserved ER-phagy receptor maintains endoplasmic reticulum homeostasis during stress

cell biology more details view paper
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    • Site-wide: 8,247
    • In cell biology: 187
  • Year to date:
    • Site-wide: 29,729
  • Since beginning of last month:
    • Site-wide: 32,654

An automated workflow for label-free and multiplexed single cell proteomics sample preparation at unprecedented sensitivity.

biochemistry more details view paper
  • Downloaded 1,563 times
  • Download rankings, all-time:
    • Site-wide: 11,779
    • In biochemistry: 226
  • Year to date:
    • Site-wide: 1,200
  • Since beginning of last month:
    • Site-wide: 1,716

Cross-linking/Mass Spectrometry: A Community-Wide, Comparative Study Towards Establishing Best Practice Guidelines

biochemistry more details view paper
  • Downloaded 1,471 times
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    • Site-wide: 12,869
    • In biochemistry: 251
  • Year to date:
    • Site-wide: 49,771
  • Since beginning of last month:
    • Site-wide: 67,129

Optimized fragmentation improves the identification of peptides cross-linked using MS-cleavable reagents

biochemistry more details view paper
  • Downloaded 1,407 times
  • Download rankings, all-time:
    • Site-wide: 13,788
    • In biochemistry: 273
  • Year to date:
    • Site-wide: 37,024
  • Since beginning of last month:
    • Site-wide: 33,262

Absolute quantification of cohesin, CTCF and their regulators in human cells

cell biology more details view paper
  • Downloaded 1,327 times
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    • Site-wide: 15,024
    • In cell biology: 441
  • Year to date:
    • Site-wide: 108,108
  • Since beginning of last month:
    • Site-wide: 66,248

N-terminal β-strand underpins biochemical specialization of an ATG8 isoform

plant biology more details view paper
  • Downloaded 1,270 times
  • Download rankings, all-time:
    • Site-wide: 16,066
    • In plant biology: 210
  • Year to date:
    • Site-wide: 95,902
  • Since beginning of last month:
    • Site-wide: 106,180

ESCO1 and CTCF enable formation of long chromatin loops by protecting cohesinSTAG1 from WAPL

cell biology more details view paper
  • Downloaded 1,122 times
  • Download rankings, all-time:
    • Site-wide: 19,341
    • In cell biology: 640
  • Year to date:
    • Site-wide: 96,391
  • Since beginning of last month:
    • Site-wide: 84,424

MTHFD1 is a genetic interactor of BRD4 and links folate metabolism to transcriptional regulation

cancer biology more details view paper
  • Downloaded 1,089 times
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    • Site-wide: 20,187
    • In cancer biology: 482
  • Year to date:
    • Site-wide: 97,900
  • Since beginning of last month:
    • Site-wide: 78,719

The linear ubiquitin chain assembly complex generates heterotypic ubiquitin chains

biochemistry more details view paper
  • Downloaded 1,072 times
  • Download rankings, all-time:
    • Site-wide: 20,645
    • In biochemistry: 441
  • Year to date:
    • Site-wide: 17,696
  • Since beginning of last month:
    • Site-wide: 29,773

The nascent RNA binding complex SFiNX licenses piRNA-guided heterochromatin formation

molecular biology more details view paper
  • Downloaded 905 times
  • Download rankings, all-time:
    • Site-wide: 26,426
    • In molecular biology: 722
  • Year to date:
    • Site-wide: 78,478
  • Since beginning of last month:
    • Site-wide: 110,575

Ultra-sensitive nanoLC-MS of sub nanogram protein samples using second generation micro pillar array LC technology with Orbitrap Exploris 480 and FAIMS PRO

cell biology more details view paper
  • Downloaded 898 times
  • Download rankings, all-time:
    • Site-wide: 26,730
    • In cell biology: 980
  • Year to date:
    • Site-wide: 2,536
  • Since beginning of last month:
    • Site-wide: 2,489

The molecular principles of Piwi-mediated co-transcriptional silencing through the dimeric SFiNX complex

molecular biology more details view paper
  • Downloaded 830 times
  • Download rankings, all-time:
    • Site-wide: 29,877
    • In molecular biology: 831
  • Year to date:
    • Site-wide: 2,852
  • Since beginning of last month:
    • Site-wide: 33,696

Autophagy mediates temporary reprogramming and dedifferentiation in plant somatic cells

plant biology more details view paper
  • Downloaded 809 times
  • Download rankings, all-time:
    • Site-wide: 30,903
    • In plant biology: 566
  • Year to date:
    • Site-wide: 52,741
  • Since beginning of last month:
    • Site-wide: 53,150

Improved Sensitivity in Low-Input Proteomics using Micro-Pillar Array-based Chromatography

biochemistry more details view paper
  • Downloaded 789 times
  • Download rankings, all-time:
    • Site-wide: 31,984
    • In biochemistry: 762
  • Year to date:
    • Site-wide: 105,498
  • Since beginning of last month:
    • Site-wide: 98,109

PHF3 regulates neuronal gene expression through the new Pol II CTD reader domain SPOC

biochemistry more details view paper
  • Downloaded 779 times
  • Download rankings, all-time:
    • Site-wide: 32,595
    • In biochemistry: 777
  • Year to date:
    • Site-wide: 18,181
  • Since beginning of last month:
    • Site-wide: 12,326

Zebrafish Ski7 tunes RNA levels during the oocyte-to-embryo transition

developmental biology more details view paper
  • Downloaded 712 times
  • Download rankings, all-time:
    • Site-wide: 36,884
    • In developmental biology: 780
  • Year to date:
    • Site-wide: 58,809
  • Since beginning of last month:
    • Site-wide: 122,986

Site-specific ubiquitination of the E3 ligase HOIP regulates cell death and immune signaling

cell biology more details view paper
  • Downloaded 578 times
  • Download rankings, all-time:
    • Site-wide: 48,207
    • In cell biology: 2,051
  • Year to date:
    • Site-wide: 41,799
  • Since beginning of last month:
    • Site-wide: 36,755

Fast and highly efficient affinity enrichment of Azide-A-DSBSO cross-linked peptides

biochemistry more details view paper
  • Downloaded 569 times
  • Download rankings, all-time:
    • Site-wide: 49,180
    • In biochemistry: 1,270
  • Year to date:
    • Site-wide: 35,482
  • Since beginning of last month:
    • Site-wide: 47,955

A synthetic peptide library for benchmarking crosslinking mass spectrometry search engines

bioinformatics more details view paper
  • Downloaded 533 times
  • Download rankings, all-time:
    • Site-wide: 53,150
    • In bioinformatics: 5,401
  • Year to date:
    • Site-wide: 96,480
  • Since beginning of last month:
    • Site-wide: 99,127

Comparative proteome signatures of trace samples by multiplexed Data-Independent Acquisition

biochemistry more details view paper
  • Downloaded 498 times
  • Download rankings, all-time:
    • Site-wide: 57,565
    • In biochemistry: 1,524
  • Year to date:
    • Site-wide: 5,928
  • Since beginning of last month:
    • Site-wide: 5,328

Crosstalk between H2A variant-specific modifications impacts vital cell functions

synthetic biology more details view paper
  • Downloaded 429 times
  • Download rankings, all-time:
    • Site-wide: 67,570
    • In synthetic biology: 788
  • Year to date:
    • Site-wide: 7,426
  • Since beginning of last month:
    • Site-wide: 28,000

Differentially accessible Cdc4 phospho-degrons regulate Ctf19CCAN kinetochore subunit stability in mitosis

cell biology more details view paper
  • Downloaded 286 times
  • Download rankings, all-time:
    • Site-wide: 94,995
    • In cell biology: 4,383
  • Year to date:
    • Site-wide: 13,131
  • Since beginning of last month:
    • Site-wide: 58,402

Bacterial-type plant ferroxidases tune local phosphate sensing in root development

plant biology more details view paper
  • Downloaded 202 times
  • Download rankings, all-time:
    • Site-wide: 114,723
    • In plant biology: 3,176
  • Year to date:
    • Site-wide: 21,039
  • Since beginning of last month:
    • Site-wide: 26,791

MSX2 safeguards syncytiotrophoblast fate of human trophoblast stem cells

molecular biology more details view paper
  • Downloaded 154 times
  • Download rankings, all-time:
    • Site-wide: 125,657
    • In molecular biology: 3,743
  • Year to date:
    • Site-wide: 29,173
  • Since beginning of last month:
    • Site-wide: 44,220

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